JP2023015159A5 - - Google Patents
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- JP2023015159A5 JP2023015159A5 JP2022172913A JP2022172913A JP2023015159A5 JP 2023015159 A5 JP2023015159 A5 JP 2023015159A5 JP 2022172913 A JP2022172913 A JP 2022172913A JP 2022172913 A JP2022172913 A JP 2022172913A JP 2023015159 A5 JP2023015159 A5 JP 2023015159A5
- Authority
- JP
- Japan
- Prior art keywords
- expression profiles
- targets
- cells
- expression
- target
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- 238000000034 method Methods 0.000 claims 24
- 239000011324 bead Substances 0.000 claims 13
- 238000012163 sequencing technique Methods 0.000 claims 9
- 239000002245 particle Substances 0.000 claims 5
- -1 polydimethylsiloxane Polymers 0.000 claims 3
- 229920000936 Agarose Polymers 0.000 claims 2
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 claims 2
- 239000002131 composite material Substances 0.000 claims 2
- 239000004205 dimethyl polysiloxane Substances 0.000 claims 2
- 238000002372 labelling Methods 0.000 claims 2
- 239000011325 microbead Substances 0.000 claims 2
- 229920000435 poly(dimethylsiloxane) Polymers 0.000 claims 2
- 238000003752 polymerase chain reaction Methods 0.000 claims 2
- 108090000623 proteins and genes Proteins 0.000 claims 2
- 102000004169 proteins and genes Human genes 0.000 claims 2
- JLBJTVDPSNHSKJ-UHFFFAOYSA-N 4-Methylstyrene Chemical compound CC1=CC=C(C=C)C=C1 JLBJTVDPSNHSKJ-UHFFFAOYSA-N 0.000 claims 1
- 108010010803 Gelatin Proteins 0.000 claims 1
- 239000004677 Nylon Substances 0.000 claims 1
- 239000004743 Polypropylene Substances 0.000 claims 1
- 239000004793 Polystyrene Substances 0.000 claims 1
- 229920002684 Sepharose Polymers 0.000 claims 1
- 108010090804 Streptavidin Proteins 0.000 claims 1
- RTAQQCXQSZGOHL-UHFFFAOYSA-N Titanium Chemical compound [Ti] RTAQQCXQSZGOHL-UHFFFAOYSA-N 0.000 claims 1
- 101710120037 Toxin CcdB Proteins 0.000 claims 1
- 230000001745 anti-biotin effect Effects 0.000 claims 1
- 239000001913 cellulose Substances 0.000 claims 1
- 229920002678 cellulose Polymers 0.000 claims 1
- 239000000919 ceramic Substances 0.000 claims 1
- 229920000159 gelatin Polymers 0.000 claims 1
- 239000008273 gelatin Substances 0.000 claims 1
- 235000019322 gelatine Nutrition 0.000 claims 1
- 235000011852 gelatine desserts Nutrition 0.000 claims 1
- 239000011521 glass Substances 0.000 claims 1
- 239000000017 hydrogel Substances 0.000 claims 1
- 239000004816 latex Substances 0.000 claims 1
- 229920000126 latex Polymers 0.000 claims 1
- 108010026228 mRNA guanylyltransferase Proteins 0.000 claims 1
- 230000005291 magnetic effect Effects 0.000 claims 1
- 239000000463 material Substances 0.000 claims 1
- 229920001778 nylon Polymers 0.000 claims 1
- 230000005298 paramagnetic effect Effects 0.000 claims 1
- 239000004033 plastic Substances 0.000 claims 1
- 229920003023 plastic Polymers 0.000 claims 1
- 229920000058 polyacrylate Polymers 0.000 claims 1
- 229920001155 polypropylene Polymers 0.000 claims 1
- 229920001296 polysiloxane Polymers 0.000 claims 1
- 229920002223 polystyrene Polymers 0.000 claims 1
- 239000000377 silicon dioxide Substances 0.000 claims 1
- 229910052719 titanium Inorganic materials 0.000 claims 1
- 239000010936 titanium Substances 0.000 claims 1
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201762476522P | 2017-03-24 | 2017-03-24 | |
| US62/476,522 | 2017-03-24 | ||
| PCT/US2018/023387 WO2018175458A2 (en) | 2017-03-24 | 2018-03-20 | Synthetic multiplets for multiplets determination |
| JP2019552517A JP7169290B2 (ja) | 2017-03-24 | 2018-03-20 | マルチプレットを決定するための合成マルチプレット |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019552517A Division JP7169290B2 (ja) | 2017-03-24 | 2018-03-20 | マルチプレットを決定するための合成マルチプレット |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2023015159A JP2023015159A (ja) | 2023-01-31 |
| JP2023015159A5 true JP2023015159A5 (enExample) | 2023-05-26 |
| JP7615109B2 JP7615109B2 (ja) | 2025-01-16 |
Family
ID=61911724
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019552517A Active JP7169290B2 (ja) | 2017-03-24 | 2018-03-20 | マルチプレットを決定するための合成マルチプレット |
| JP2022172913A Active JP7615109B2 (ja) | 2017-03-24 | 2022-10-28 | マルチプレットを決定するための合成マルチプレット |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019552517A Active JP7169290B2 (ja) | 2017-03-24 | 2018-03-20 | マルチプレットを決定するための合成マルチプレット |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US20180276332A1 (enExample) |
| EP (2) | EP3601606A2 (enExample) |
| JP (2) | JP7169290B2 (enExample) |
| CN (1) | CN110446789A (enExample) |
| WO (1) | WO2018175458A2 (enExample) |
Families Citing this family (38)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8835358B2 (en) | 2009-12-15 | 2014-09-16 | Cellular Research, Inc. | Digital counting of individual molecules by stochastic attachment of diverse labels |
| GB2513024B (en) | 2012-02-27 | 2016-08-31 | Cellular Res Inc | A clonal amplification method |
| ES2857908T3 (es) | 2013-08-28 | 2021-09-29 | Becton Dickinson Co | Análisis masivamente paralelo de células individuales |
| ES2836802T3 (es) | 2015-02-27 | 2021-06-28 | Becton Dickinson Co | Códigos de barras moleculares espacialmente direccionables |
| EP4180535A1 (en) | 2015-03-30 | 2023-05-17 | Becton, Dickinson and Company | Methods and compositions for combinatorial barcoding |
| EP4582556A3 (en) | 2015-04-23 | 2025-10-08 | Becton, Dickinson and Company | Methods and compositions for whole transcriptome amplification |
| ES2745694T3 (es) | 2015-09-11 | 2020-03-03 | Cellular Res Inc | Métodos y composiciones para normalización de biblioteca de ácido nucleico |
| US10301677B2 (en) | 2016-05-25 | 2019-05-28 | Cellular Research, Inc. | Normalization of nucleic acid libraries |
| ES2979395T3 (es) | 2016-05-26 | 2024-09-25 | Becton Dickinson Co | Métodos de ajuste del recuento de etiquetas moleculares |
| US10202641B2 (en) | 2016-05-31 | 2019-02-12 | Cellular Research, Inc. | Error correction in amplification of samples |
| US10640763B2 (en) | 2016-05-31 | 2020-05-05 | Cellular Research, Inc. | Molecular indexing of internal sequences |
| KR102522023B1 (ko) | 2016-09-26 | 2023-04-17 | 셀룰러 리서치, 인크. | 바코딩된 올리고뉴클레오티드 서열을 갖는 시약을 이용한 단백질 발현의 측정 |
| WO2018089378A1 (en) | 2016-11-08 | 2018-05-17 | Cellular Research, Inc. | Methods for expression profile classification |
| US11608497B2 (en) | 2016-11-08 | 2023-03-21 | Becton, Dickinson And Company | Methods for cell label classification |
| EP3577232A1 (en) | 2017-02-01 | 2019-12-11 | Cellular Research, Inc. | Selective amplification using blocking oligonucleotides |
| KR102790050B1 (ko) | 2017-06-05 | 2025-04-04 | 백톤 디킨슨 앤드 컴퍼니 | 단일 세포를 위한 샘플 인덱싱 |
| EP4545647A3 (en) | 2018-05-03 | 2025-07-09 | Becton, Dickinson and Company | Molecular barcoding on opposite transcript ends |
| WO2019213294A1 (en) | 2018-05-03 | 2019-11-07 | Becton, Dickinson And Company | High throughput multiomics sample analysis |
| US11615208B2 (en) * | 2018-07-06 | 2023-03-28 | Capital One Services, Llc | Systems and methods for synthetic data generation |
| EP4471156A3 (en) | 2018-10-01 | 2025-02-26 | Becton, Dickinson and Company | Determining 5' transcript sequences |
| JP7618548B2 (ja) | 2018-11-08 | 2025-01-21 | ベクトン・ディキンソン・アンド・カンパニー | ランダムプライミングを使用した単一細胞の全トランスクリプトーム解析 |
| WO2020123384A1 (en) | 2018-12-13 | 2020-06-18 | Cellular Research, Inc. | Selective extension in single cell whole transcriptome analysis |
| ES2989967T3 (es) | 2019-01-23 | 2024-11-28 | Becton Dickinson Co | Oligonucleótidos asociados con anticuerpos |
| US12071617B2 (en) | 2019-02-14 | 2024-08-27 | Becton, Dickinson And Company | Hybrid targeted and whole transcriptome amplification |
| WO2020214642A1 (en) * | 2019-04-19 | 2020-10-22 | Becton, Dickinson And Company | Methods of associating phenotypical data and single cell sequencing data |
| CN120099137A (zh) | 2019-07-22 | 2025-06-06 | 贝克顿迪金森公司 | 单细胞染色质免疫沉淀测序测定 |
| CN114729350A (zh) | 2019-11-08 | 2022-07-08 | 贝克顿迪金森公司 | 使用随机引发获得用于免疫组库测序的全长v(d)j信息 |
| US11649497B2 (en) | 2020-01-13 | 2023-05-16 | Becton, Dickinson And Company | Methods and compositions for quantitation of proteins and RNA |
| EP4090764A1 (en) * | 2020-01-13 | 2022-11-23 | Becton, Dickinson and Company | Cell capture using du-containing oligonucleotides |
| WO2021155057A1 (en) | 2020-01-29 | 2021-08-05 | Becton, Dickinson And Company | Barcoded wells for spatial mapping of single cells through sequencing |
| WO2021173719A1 (en) | 2020-02-25 | 2021-09-02 | Becton, Dickinson And Company | Bi-specific probes to enable the use of single-cell samples as single color compensation control |
| EP4150118A1 (en) | 2020-05-14 | 2023-03-22 | Becton Dickinson and Company | Primers for immune repertoire profiling |
| EP4158055B1 (en) | 2020-06-02 | 2024-03-27 | Becton, Dickinson and Company | Oligonucleotides and beads for 5 prime gene expression assay |
| US11932901B2 (en) | 2020-07-13 | 2024-03-19 | Becton, Dickinson And Company | Target enrichment using nucleic acid probes for scRNAseq |
| WO2022026909A1 (en) | 2020-07-31 | 2022-02-03 | Becton, Dickinson And Company | Single cell assay for transposase-accessible chromatin |
| US11739443B2 (en) | 2020-11-20 | 2023-08-29 | Becton, Dickinson And Company | Profiling of highly expressed and lowly expressed proteins |
| US12392771B2 (en) | 2020-12-15 | 2025-08-19 | Becton, Dickinson And Company | Single cell secretome analysis |
| CN117729047B (zh) * | 2023-12-29 | 2024-06-21 | 北京网藤科技有限公司 | 一种用于工控网络流量审计的智能学习引擎方法及系统 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8835358B2 (en) * | 2009-12-15 | 2014-09-16 | Cellular Research, Inc. | Digital counting of individual molecules by stochastic attachment of diverse labels |
| ES2857908T3 (es) | 2013-08-28 | 2021-09-29 | Becton Dickinson Co | Análisis masivamente paralelo de células individuales |
| CN107873054B (zh) * | 2014-09-09 | 2022-07-12 | 博德研究所 | 用于复合单细胞核酸分析的基于微滴的方法和设备 |
| EP3248018B1 (en) | 2015-01-22 | 2020-01-08 | Becton, Dickinson and Company | Devices and systems for molecular barcoding of nucleic acid targets in single cells |
| ES2836802T3 (es) * | 2015-02-27 | 2021-06-28 | Becton Dickinson Co | Códigos de barras moleculares espacialmente direccionables |
| KR102790050B1 (ko) | 2017-06-05 | 2025-04-04 | 백톤 디킨슨 앤드 컴퍼니 | 단일 세포를 위한 샘플 인덱싱 |
-
2018
- 2018-03-20 WO PCT/US2018/023387 patent/WO2018175458A2/en not_active Ceased
- 2018-03-20 CN CN201880019445.0A patent/CN110446789A/zh active Pending
- 2018-03-20 EP EP18716453.8A patent/EP3601606A2/en not_active Withdrawn
- 2018-03-20 US US15/926,977 patent/US20180276332A1/en active Pending
- 2018-03-20 JP JP2019552517A patent/JP7169290B2/ja active Active
- 2018-03-20 EP EP22208796.7A patent/EP4159871B1/en active Active
-
2022
- 2022-10-28 JP JP2022172913A patent/JP7615109B2/ja active Active
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