JP2020513837A5 - - Google Patents
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- JP2020513837A5 JP2020513837A5 JP2019552517A JP2019552517A JP2020513837A5 JP 2020513837 A5 JP2020513837 A5 JP 2020513837A5 JP 2019552517 A JP2019552517 A JP 2019552517A JP 2019552517 A JP2019552517 A JP 2019552517A JP 2020513837 A5 JP2020513837 A5 JP 2020513837A5
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- 230000014509 gene expression Effects 0.000 claims description 463
- 238000000034 method Methods 0.000 claims description 190
- 238000010801 machine learning Methods 0.000 claims description 42
- 238000012163 sequencing technique Methods 0.000 claims description 34
- 108090000623 proteins and genes Proteins 0.000 claims description 15
- 238000002372 labelling Methods 0.000 claims description 10
- 102000004169 proteins and genes Human genes 0.000 claims description 8
- 108020004999 messenger RNA Proteins 0.000 claims description 5
- 238000004422 calculation algorithm Methods 0.000 claims description 4
- 230000002068 genetic effect Effects 0.000 claims description 4
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Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2022172913A JP7615109B2 (ja) | 2017-03-24 | 2022-10-28 | マルチプレットを決定するための合成マルチプレット |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201762476522P | 2017-03-24 | 2017-03-24 | |
| US62/476,522 | 2017-03-24 | ||
| PCT/US2018/023387 WO2018175458A2 (en) | 2017-03-24 | 2018-03-20 | Synthetic multiplets for multiplets determination |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022172913A Division JP7615109B2 (ja) | 2017-03-24 | 2022-10-28 | マルチプレットを決定するための合成マルチプレット |
Publications (4)
| Publication Number | Publication Date |
|---|---|
| JP2020513837A JP2020513837A (ja) | 2020-05-21 |
| JP2020513837A5 true JP2020513837A5 (enExample) | 2021-04-30 |
| JPWO2018175458A5 JPWO2018175458A5 (enExample) | 2022-06-07 |
| JP7169290B2 JP7169290B2 (ja) | 2022-11-10 |
Family
ID=61911724
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019552517A Active JP7169290B2 (ja) | 2017-03-24 | 2018-03-20 | マルチプレットを決定するための合成マルチプレット |
| JP2022172913A Active JP7615109B2 (ja) | 2017-03-24 | 2022-10-28 | マルチプレットを決定するための合成マルチプレット |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022172913A Active JP7615109B2 (ja) | 2017-03-24 | 2022-10-28 | マルチプレットを決定するための合成マルチプレット |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US20180276332A1 (enExample) |
| EP (2) | EP4159871B1 (enExample) |
| JP (2) | JP7169290B2 (enExample) |
| CN (1) | CN110446789A (enExample) |
| WO (1) | WO2018175458A2 (enExample) |
Families Citing this family (38)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8835358B2 (en) | 2009-12-15 | 2014-09-16 | Cellular Research, Inc. | Digital counting of individual molecules by stochastic attachment of diverse labels |
| GB2513024B (en) | 2012-02-27 | 2016-08-31 | Cellular Res Inc | A clonal amplification method |
| GB2546833B (en) | 2013-08-28 | 2018-04-18 | Cellular Res Inc | Microwell for single cell analysis comprising single cell and single bead oligonucleotide capture labels |
| EP3262192B1 (en) | 2015-02-27 | 2020-09-16 | Becton, Dickinson and Company | Spatially addressable molecular barcoding |
| WO2016160844A2 (en) | 2015-03-30 | 2016-10-06 | Cellular Research, Inc. | Methods and compositions for combinatorial barcoding |
| EP3286326B1 (en) | 2015-04-23 | 2025-01-22 | Becton, Dickinson and Company | Method for whole transcriptome amplification |
| EP3347465B1 (en) | 2015-09-11 | 2019-06-26 | Cellular Research, Inc. | Methods and compositions for nucleic acid library normalization |
| US10301677B2 (en) | 2016-05-25 | 2019-05-28 | Cellular Research, Inc. | Normalization of nucleic acid libraries |
| ES2979395T3 (es) | 2016-05-26 | 2024-09-25 | Becton Dickinson Co | Métodos de ajuste del recuento de etiquetas moleculares |
| US10202641B2 (en) | 2016-05-31 | 2019-02-12 | Cellular Research, Inc. | Error correction in amplification of samples |
| US10640763B2 (en) | 2016-05-31 | 2020-05-05 | Cellular Research, Inc. | Molecular indexing of internal sequences |
| CN109791157B (zh) | 2016-09-26 | 2022-06-07 | 贝克顿迪金森公司 | 使用具有条形码化的寡核苷酸序列的试剂测量蛋白质表达 |
| CN109906274B (zh) | 2016-11-08 | 2023-08-25 | 贝克顿迪金森公司 | 用于细胞标记分类的方法 |
| EP3539035B1 (en) | 2016-11-08 | 2024-04-17 | Becton, Dickinson and Company | Methods for expression profile classification |
| WO2018144240A1 (en) | 2017-02-01 | 2018-08-09 | Cellular Research, Inc. | Selective amplification using blocking oligonucleotides |
| AU2018281745B2 (en) | 2017-06-05 | 2022-05-19 | Becton, Dickinson And Company | Sample indexing for single cells |
| EP3788170B1 (en) | 2018-05-03 | 2025-01-01 | Becton, Dickinson and Company | Molecular barcoding on opposite transcript ends |
| ES2945191T3 (es) | 2018-05-03 | 2023-06-29 | Becton Dickinson Co | Análisis de muestras multiómicas de alto rendimiento |
| US12455778B2 (en) * | 2018-07-06 | 2025-10-28 | Capital One Services, Llc | Systems and methods for data stream simulation |
| EP4471156A3 (en) | 2018-10-01 | 2025-02-26 | Becton, Dickinson and Company | Determining 5' transcript sequences |
| WO2020097315A1 (en) | 2018-11-08 | 2020-05-14 | Cellular Research, Inc. | Whole transcriptome analysis of single cells using random priming |
| CN113195717A (zh) | 2018-12-13 | 2021-07-30 | 贝克顿迪金森公司 | 单细胞全转录组分析中的选择性延伸 |
| WO2020154247A1 (en) | 2019-01-23 | 2020-07-30 | Cellular Research, Inc. | Oligonucleotides associated with antibodies |
| EP3924506A1 (en) * | 2019-02-14 | 2021-12-22 | Becton Dickinson and Company | Hybrid targeted and whole transcriptome amplification |
| US11965208B2 (en) | 2019-04-19 | 2024-04-23 | Becton, Dickinson And Company | Methods of associating phenotypical data and single cell sequencing data |
| CN114051534B (zh) | 2019-07-22 | 2025-02-21 | 贝克顿迪金森公司 | 单细胞染色质免疫沉淀测序测定 |
| EP4407041A3 (en) | 2019-11-08 | 2024-09-25 | Becton Dickinson and Company | Using random priming to obtain full-length v(d)j information for immune repertoire sequencing |
| WO2021146219A1 (en) * | 2020-01-13 | 2021-07-22 | Becton, Dickinson And Company | Cell capture using du-containing oligonucleotides |
| US11649497B2 (en) | 2020-01-13 | 2023-05-16 | Becton, Dickinson And Company | Methods and compositions for quantitation of proteins and RNA |
| EP4471155A3 (en) | 2020-01-29 | 2024-12-18 | Becton, Dickinson and Company | Barcoded wells for spatial mapping of single cells through sequencing |
| CN115151810A (zh) | 2020-02-25 | 2022-10-04 | 贝克顿迪金森公司 | 实现使用单细胞样品作为单色补偿对照的双特异性探针 |
| CN115605614A (zh) | 2020-05-14 | 2023-01-13 | 贝克顿迪金森公司（Us） | 用于免疫组库谱分析的引物 |
| US12157913B2 (en) | 2020-06-02 | 2024-12-03 | Becton, Dickinson And Company | Oligonucleotides and beads for 5 prime gene expression assay |
| US11932901B2 (en) | 2020-07-13 | 2024-03-19 | Becton, Dickinson And Company | Target enrichment using nucleic acid probes for scRNAseq |
| US12391940B2 (en) | 2020-07-31 | 2025-08-19 | Becton, Dickinson And Company | Single cell assay for transposase-accessible chromatin |
| US11739443B2 (en) | 2020-11-20 | 2023-08-29 | Becton, Dickinson And Company | Profiling of highly expressed and lowly expressed proteins |
| US12392771B2 (en) | 2020-12-15 | 2025-08-19 | Becton, Dickinson And Company | Single cell secretome analysis |
| CN117729047B (zh) * | 2023-12-29 | 2024-06-21 | 北京网藤科技有限公司 | 一种用于工控网络流量审计的智能学习引擎方法及系统 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8835358B2 (en) * | 2009-12-15 | 2014-09-16 | Cellular Research, Inc. | Digital counting of individual molecules by stochastic attachment of diverse labels |
| GB2546833B (en) | 2013-08-28 | 2018-04-18 | Cellular Res Inc | Microwell for single cell analysis comprising single cell and single bead oligonucleotide capture labels |
| EP4105337A1 (en) | 2014-09-09 | 2022-12-21 | The Broad Institute, Inc. | A droplet-based method and apparatus for composite single-cell nucleic acid analysis |
| CN107407691B (zh) | 2015-01-22 | 2021-07-27 | 贝克顿迪金森公司 | 用于单细胞中核酸靶标的分子条码化的装置和系统 |
| EP3262192B1 (en) * | 2015-02-27 | 2020-09-16 | Becton, Dickinson and Company | Spatially addressable molecular barcoding |
| AU2018281745B2 (en) | 2017-06-05 | 2022-05-19 | Becton, Dickinson And Company | Sample indexing for single cells |
-
2018
- 2018-03-20 CN CN201880019445.0A patent/CN110446789A/zh active Pending
- 2018-03-20 EP EP22208796.7A patent/EP4159871B1/en active Active
- 2018-03-20 JP JP2019552517A patent/JP7169290B2/ja active Active
- 2018-03-20 WO PCT/US2018/023387 patent/WO2018175458A2/en not_active Ceased
- 2018-03-20 EP EP18716453.8A patent/EP3601606A2/en not_active Withdrawn
- 2018-03-20 US US15/926,977 patent/US20180276332A1/en active Pending
-
2022
- 2022-10-28 JP JP2022172913A patent/JP7615109B2/ja active Active
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