JP2022553328A5 - - Google Patents
Info
- Publication number
- JP2022553328A5 JP2022553328A5 JP2022523593A JP2022523593A JP2022553328A5 JP 2022553328 A5 JP2022553328 A5 JP 2022553328A5 JP 2022523593 A JP2022523593 A JP 2022523593A JP 2022523593 A JP2022523593 A JP 2022523593A JP 2022553328 A5 JP2022553328 A5 JP 2022553328A5
- Authority
- JP
- Japan
- Prior art keywords
- hla
- transgenic pig
- polypeptide
- sla
- derived
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2025080039A JP2025109839A (ja) | 2019-10-22 | 2025-05-12 | トランスジェニックブタ、その作製方法と用途、およびヒト免疫系マウスの作製方法 |
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201962924228P | 2019-10-22 | 2019-10-22 | |
| US62/924,228 | 2019-10-22 | ||
| US201962925859P | 2019-10-25 | 2019-10-25 | |
| US62/925,859 | 2019-10-25 | ||
| PCT/US2020/056771 WO2021081156A1 (en) | 2019-10-22 | 2020-10-22 | Transgenic swine, methods of making and uses thereof, and methods of making human immune system mice |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2025080039A Division JP2025109839A (ja) | 2019-10-22 | 2025-05-12 | トランスジェニックブタ、その作製方法と用途、およびヒト免疫系マウスの作製方法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2022553328A JP2022553328A (ja) | 2022-12-22 |
| JP2022553328A5 true JP2022553328A5 (enExample) | 2023-10-27 |
| JP7685249B2 JP7685249B2 (ja) | 2025-05-29 |
Family
ID=75620265
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022523593A Active JP7685249B2 (ja) | 2019-10-22 | 2020-10-22 | トランスジェニックブタ、その作製方法と用途、およびヒト免疫系マウスの作製方法 |
| JP2025080039A Pending JP2025109839A (ja) | 2019-10-22 | 2025-05-12 | トランスジェニックブタ、その作製方法と用途、およびヒト免疫系マウスの作製方法 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2025080039A Pending JP2025109839A (ja) | 2019-10-22 | 2025-05-12 | トランスジェニックブタ、その作製方法と用途、およびヒト免疫系マウスの作製方法 |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US20220279767A1 (enExample) |
| EP (1) | EP4048802A4 (enExample) |
| JP (2) | JP7685249B2 (enExample) |
| KR (1) | KR20220084296A (enExample) |
| CN (1) | CN114585744A (enExample) |
| AU (1) | AU2020370254B2 (enExample) |
| CA (1) | CA3155234A1 (enExample) |
| IL (1) | IL292406A (enExample) |
| WO (1) | WO2021081156A1 (enExample) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US10883084B2 (en) | 2018-10-05 | 2021-01-05 | Xenotherapeutics, Inc. | Personalized cells, tissues, and organs for transplantation from a humanized, bespoke, designated-pathogen free, (non-human) donor and methods and products relating to same |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2227584A1 (en) * | 1995-08-04 | 1997-02-20 | The General Hospital Corporation | Transgenic swine and swine cells having human hla genes |
| US6639122B1 (en) * | 2000-09-19 | 2003-10-28 | Animal Technology Institute Taiwan | Transgenic swine having HLA-D gene, swine cells thereof and xenografts therefrom |
| CA2822117A1 (en) * | 2010-12-31 | 2012-07-05 | The Trustees Of Columbia University In The City Of New York | Generation of autologous t-cells in mice |
| JP2014513948A (ja) * | 2011-04-20 | 2014-06-19 | ザ ユニバーシティ オブ ワシントン スルー イッツ センター フォー コマーシャライゼーション | β２ミクログロブリン欠損細胞 |
| RS63220B1 (sr) * | 2011-10-28 | 2022-06-30 | Regeneron Pharma | Genetski modifikovani miševi sa ekspresijom himernih molekula klase ii glavnog kompleksa histokompatibilnosti (mhc) |
| WO2015056774A1 (ja) * | 2013-10-18 | 2015-04-23 | 大鵬薬品工業株式会社 | Ｈｌａクラスｉ発現非ヒト動物 |
| EP3229586B1 (en) * | 2014-12-10 | 2025-07-30 | Regents of the University of Minnesota | Genetically modified cells, tissues, and organs for treating disease |
| EP3313176A4 (en) * | 2015-06-26 | 2019-06-26 | Indiana University Research&technology Corporation | TRANSGENIC PIGS WITH GENETIC MODIFICATIONS OF SLA |
| JP7139419B2 (ja) * | 2017-09-29 | 2022-09-20 | リジェネロン・ファーマシューティカルズ・インコーポレイテッド | ヒト化ｔｔｒ遺伝子座を含む非ヒト動物および使用方法 |
| KR20210089659A (ko) * | 2018-10-05 | 2021-07-16 | 제노세라퓨틱스, 인코포레이티드 | 이종이식 생성물 및 방법 |
-
2020
- 2020-10-22 AU AU2020370254A patent/AU2020370254B2/en active Active
- 2020-10-22 CA CA3155234A patent/CA3155234A1/en active Pending
- 2020-10-22 WO PCT/US2020/056771 patent/WO2021081156A1/en not_active Ceased
- 2020-10-22 EP EP20880160.5A patent/EP4048802A4/en active Pending
- 2020-10-22 JP JP2022523593A patent/JP7685249B2/ja active Active
- 2020-10-22 KR KR1020227012957A patent/KR20220084296A/ko active Pending
- 2020-10-22 IL IL292406A patent/IL292406A/en unknown
- 2020-10-22 CN CN202180005989.3A patent/CN114585744A/zh active Pending
-
2022
- 2022-04-18 US US17/722,697 patent/US20220279767A1/en active Pending
-
2025
- 2025-05-12 JP JP2025080039A patent/JP2025109839A/ja active Pending
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