JP2022551672A - 乳癌治療法 - Google Patents

乳癌治療法 Download PDF

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Publication number
JP2022551672A
JP2022551672A JP2022522322A JP2022522322A JP2022551672A JP 2022551672 A JP2022551672 A JP 2022551672A JP 2022522322 A JP2022522322 A JP 2022522322A JP 2022522322 A JP2022522322 A JP 2022522322A JP 2022551672 A JP2022551672 A JP 2022551672A
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Prior art keywords
breast cancer
dapanthril
mice
tumor
dapanstril
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JP2022522322A
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Japanese (ja)
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JP2022551672A5 (cg-RX-API-DMAC10.html
Inventor
エー．ディナレロ チャールズ
テンゲスダル アイザック
Original Assignee
オラテック セラピューティクス リミティド ライアビリティ カンパニー
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Publication of JP2022551672A publication Critical patent/JP2022551672A/ja
Publication of JP2022551672A5 publication Critical patent/JP2022551672A5/ja
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/275—Nitriles; Isonitriles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/3955—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C07K16/244—Interleukins [IL]
    • C07K16/245—IL-1
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C07K16/2818—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against CD28 or CD152
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Endocrinology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Peptides Or Proteins (AREA)
JP2022522322A 2019-10-14 2020-10-12 乳癌治療法 Pending JP2022551672A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201962914833P 2019-10-14 2019-10-14
US62/914,833 2019-10-14
PCT/US2020/055219 WO2021076444A1 (en) 2019-10-14 2020-10-12 Methods for treating breast cancer

Publications (2)

Publication Number Publication Date
JP2022551672A true JP2022551672A (ja) 2022-12-12
JP2022551672A5 JP2022551672A5 (cg-RX-API-DMAC10.html) 2023-09-20

Family

ID=75538857

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2022522322A Pending JP2022551672A (ja) 2019-10-14 2020-10-12 乳癌治療法

Country Status (6)

Country Link
US (1) US12582628B2 (cg-RX-API-DMAC10.html)
EP (1) EP4045009A4 (cg-RX-API-DMAC10.html)
JP (1) JP2022551672A (cg-RX-API-DMAC10.html)
CN (1) CN114555053B (cg-RX-API-DMAC10.html)
AU (1) AU2020366300B2 (cg-RX-API-DMAC10.html)
WO (1) WO2021076444A1 (cg-RX-API-DMAC10.html)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2025501657A (ja) * 2022-01-10 2025-01-22 オラテック セラピューティクス， インコーポレイティド 膵臓がんを治療するための方法
EP4487122A4 (en) * 2022-03-02 2026-03-11 Olatec Therapeutics Inc TREATMENT METHODS FOR PATIENTS WITH SOLID CANCER AND CLONAL HEMATOPOIESIS OF UNDETERMINED POTENTIAL
WO2026035767A1 (en) * 2024-08-06 2026-02-12 Olatec Therapeutics, Inc. Methods for treating melanoma metastasis to liver and lungs

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2019182981A1 (en) * 2018-03-21 2019-09-26 Olatec Therapeutics Llc Methods for treating melanoma

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX2013006708A (es) 2010-12-15 2013-09-13 Olatec Ind Llc Composicion de 3-metanosulfonilpropionitrilo para el tratamiento de la inflamacion y el dolor.
CN104768553A (zh) * 2012-11-02 2015-07-08 默克专利股份公司 用于治疗肝细胞癌(hcc)的6-氧代-1,6-二氢-哒嗪衍生物
UA122479C2 (uk) * 2014-01-24 2020-11-25 Дана-Фарбер Кенсер Інстітьют, Інк. Виділена молекула антитіла, яка зв’язується з людським білком програмованої смерті-1 (pd-1)
ES2970485T3 (es) * 2017-01-06 2024-05-29 Olatec Therapeutics Llc Composición farmacéutica para su uso en el tratamiento de enfermedades cardiovasculares
EP3589370A4 (en) * 2017-01-06 2020-11-18 Olatec Therapeutics LLC MULTIPLE SCLEROSIS TREATMENT METHOD
AU2018313164A1 (en) * 2017-08-11 2020-03-19 Olatec Therapeutics Llc Method for treating Schnitzler's syndrome
WO2019152627A1 (en) * 2018-01-31 2019-08-08 Olatec Therapeutics Llc Method for preventing or treating alzheimer's disease

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2019182981A1 (en) * 2018-03-21 2019-09-26 Olatec Therapeutics Llc Methods for treating melanoma

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
NAT. COMMUN., vol. 10:4375, JPN6024034937, September 2019 (2019-09-01), ISSN: 0005519820 *
PROC. NATL. ACAD. SCI., vol. 116, no. 4, JPN6024034935, January 2019 (2019-01-01), pages 1361 - 1369, ISSN: 0005519822 *
PROTEIN CELL, vol. 5(1), JPN6024034936, 2014, pages 12 - 20, ISSN: 0005519821 *

Also Published As

Publication number Publication date
AU2020366300B2 (en) 2026-05-21
EP4045009A4 (en) 2023-11-01
CN114555053A (zh) 2022-05-27
CN114555053B (zh) 2025-09-30
EP4045009A1 (en) 2022-08-24
WO2021076444A1 (en) 2021-04-22
US20220249425A1 (en) 2022-08-11
AU2020366300A1 (en) 2022-06-02
US12582628B2 (en) 2026-03-24

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