JP2022550608A5 - - Google Patents
Info
- Publication number
- JP2022550608A5 JP2022550608A5 JP2022520780A JP2022520780A JP2022550608A5 JP 2022550608 A5 JP2022550608 A5 JP 2022550608A5 JP 2022520780 A JP2022520780 A JP 2022520780A JP 2022520780 A JP2022520780 A JP 2022520780A JP 2022550608 A5 JP2022550608 A5 JP 2022550608A5
- Authority
- JP
- Japan
- Prior art keywords
- pharmaceutical composition
- cells
- fusion protein
- disease
- prion disease
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201962909725P | 2019-10-02 | 2019-10-02 | |
| US62/909,725 | 2019-10-02 | ||
| US202063023197P | 2020-05-11 | 2020-05-11 | |
| US63/023,197 | 2020-05-11 | ||
| PCT/US2020/054140 WO2021067864A1 (en) | 2019-10-02 | 2020-10-02 | Zinc finger protein transcription factors for treatment of prion disease |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2022550608A JP2022550608A (ja) | 2022-12-02 |
| JP2022550608A5 true JP2022550608A5 (https=) | 2023-09-29 |
| JP7824873B2 JP7824873B2 (ja) | 2026-03-05 |
Family
ID=73013822
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022520780A Active JP7824873B2 (ja) | 2019-10-02 | 2020-10-02 | プリオン病の治療のためのジンクフィンガータンパク質転写因子 |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US20230002459A1 (https=) |
| EP (1) | EP4041271A1 (https=) |
| JP (1) | JP7824873B2 (https=) |
| CN (1) | CN114728037A (https=) |
| WO (1) | WO2021067864A1 (https=) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20250165443A (ko) | 2023-02-17 | 2025-11-25 | 화이트헤드 인스티튜트 포 바이오메디칼 리서치 | 후성유전학적 변형 제조를 위한 조성물 및 방법 |
| WO2025160155A1 (en) | 2024-01-22 | 2025-07-31 | The Broad Institute, Inc. | Epigenetic targeting of prion diseases |
| WO2025194009A1 (en) * | 2024-03-13 | 2025-09-18 | Sangamo Therapeutics, Inc. | Zinc finger proteins for treating prion disease |
Family Cites Families (29)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5420032A (en) | 1991-12-23 | 1995-05-30 | Universitge Laval | Homing endonuclease which originates from chlamydomonas eugametos and recognizes and cleaves a 15, 17 or 19 degenerate double stranded nucleotide sequence |
| US5792632A (en) | 1992-05-05 | 1998-08-11 | Institut Pasteur | Nucleotide sequence encoding the enzyme I-SceI and the uses thereof |
| DE69534629D1 (de) | 1994-01-18 | 2005-12-29 | Scripps Research Inst | Derivate von zinkfingerproteinen und methoden |
| US6140466A (en) | 1994-01-18 | 2000-10-31 | The Scripps Research Institute | Zinc finger protein derivatives and methods therefor |
| GB9824544D0 (en) | 1998-11-09 | 1999-01-06 | Medical Res Council | Screening system |
| USRE39229E1 (en) | 1994-08-20 | 2006-08-08 | Gendaq Limited | Binding proteins for recognition of DNA |
| US5789538A (en) | 1995-02-03 | 1998-08-04 | Massachusetts Institute Of Technology | Zinc finger proteins with high affinity new DNA binding specificities |
| US5925523A (en) | 1996-08-23 | 1999-07-20 | President & Fellows Of Harvard College | Intraction trap assay, reagents and uses thereof |
| GB9710807D0 (en) | 1997-05-23 | 1997-07-23 | Medical Res Council | Nucleic acid binding proteins |
| GB9710809D0 (en) | 1997-05-23 | 1997-07-23 | Medical Res Council | Nucleic acid binding proteins |
| ES2341926T3 (es) | 1998-03-02 | 2010-06-29 | Massachusetts Institute Of Technology | Poliproteinas con dedos de cinc que tienen enlazadores mejorados. |
| US6140081A (en) | 1998-10-16 | 2000-10-31 | The Scripps Research Institute | Zinc finger binding domains for GNN |
| US6453242B1 (en) | 1999-01-12 | 2002-09-17 | Sangamo Biosciences, Inc. | Selection of sites for targeting by zinc finger proteins and methods of designing zinc finger proteins to bind to preselected sites |
| US6534261B1 (en) | 1999-01-12 | 2003-03-18 | Sangamo Biosciences, Inc. | Regulation of endogenous gene expression in cells using zinc finger proteins |
| US20020061512A1 (en) | 2000-02-18 | 2002-05-23 | Kim Jin-Soo | Zinc finger domains and methods of identifying same |
| WO2001073107A1 (en) * | 2000-03-24 | 2001-10-04 | University Of Massachusetts, A Public Institution Of The Commonwealt Of Massachusettes, As Represented By Its Amherst Campus | Prion-free transgenic ungulates |
| AU2001263155A1 (en) | 2000-05-16 | 2001-11-26 | Massachusetts Institute Of Technology | Methods and compositions for interaction trap assays |
| JP2002060786A (ja) | 2000-08-23 | 2002-02-26 | Kao Corp | 硬質表面用殺菌防汚剤 |
| US20050235369A1 (en) * | 2001-03-28 | 2005-10-20 | Yen Choo | Gene regulation II |
| GB0108491D0 (en) | 2001-04-04 | 2001-05-23 | Gendaq Ltd | Engineering zinc fingers |
| WO2003011016A2 (en) * | 2001-07-31 | 2003-02-13 | Stell | Genetically modified cows having reduced susceptibility to mad cow disease |
| JP2005500061A (ja) | 2001-08-20 | 2005-01-06 | ザ スクリップス リサーチ インスティテュート | Ｃｎｎについての亜鉛フィンガー結合ドメイン |
| ES2582091T3 (es) | 2005-10-18 | 2016-09-09 | Precision Biosciences | Meganucleasas diseñadas racionalmente con especificidad de secuencia y afinidad de unión a ADN alteradas |
| US20110023147A1 (en) * | 2008-12-04 | 2011-01-27 | Sigma-Aldrich Co. | Genomic editing of prion disorder-related genes in animals |
| US8586526B2 (en) | 2010-05-17 | 2013-11-19 | Sangamo Biosciences, Inc. | DNA-binding proteins and uses thereof |
| HRP20200254T1 (hr) | 2010-05-03 | 2020-05-29 | Sangamo Therapeutics, Inc. | Pripravci za povezivanje modula cink fingera |
| US20120225922A1 (en) * | 2011-03-04 | 2012-09-06 | Qr Pharma | Effective Amounts of (3aR)-1,3a,8-Trimethyl-1,2,3,3a,8,8a-hexahydropyrrolo [2,3-b]indol-5-yl Phenylcarbamate and Methods of Treating or Preventing Neurodegeneration |
| CN102277356B (zh) * | 2011-07-28 | 2012-10-03 | 扬州大学 | 一种山羊朊病毒基因敲除方法 |
| KR102455249B1 (ko) | 2016-08-24 | 2022-10-17 | 상가모 테라퓨틱스, 인코포레이티드 | 가공된 표적 특이적 뉴클레아제 |
-
2020
- 2020-10-02 JP JP2022520780A patent/JP7824873B2/ja active Active
- 2020-10-02 CN CN202080080713.7A patent/CN114728037A/zh active Pending
- 2020-10-02 WO PCT/US2020/054140 patent/WO2021067864A1/en not_active Ceased
- 2020-10-02 US US17/766,083 patent/US20230002459A1/en active Pending
- 2020-10-02 EP EP20796992.4A patent/EP4041271A1/en active Pending
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