JP2022544246A5 - - Google Patents
Info
- Publication number
- JP2022544246A5 JP2022544246A5 JP2022508564A JP2022508564A JP2022544246A5 JP 2022544246 A5 JP2022544246 A5 JP 2022544246A5 JP 2022508564 A JP2022508564 A JP 2022508564A JP 2022508564 A JP2022508564 A JP 2022508564A JP 2022544246 A5 JP2022544246 A5 JP 2022544246A5
- Authority
- JP
- Japan
Links
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201962885947P | 2019-08-13 | 2019-08-13 | |
| US62/885,947 | 2019-08-13 | ||
| GBPCT/GB2020/051831 | 2020-07-30 | ||
| PCT/GB2020/051831 WO2021019246A1 (en) | 2019-07-30 | 2020-07-30 | Heterotandem bicyclic peptide complexes |
| PCT/GB2020/051923 WO2021028686A1 (en) | 2019-08-13 | 2020-08-13 | Modified multimeric bicyclic peptide ligands |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2022544246A JP2022544246A (ja) | 2022-10-17 |
| JPWO2021028686A5 JPWO2021028686A5 (https=) | 2023-08-25 |
| JP2022544246A5 true JP2022544246A5 (https=) | 2023-08-25 |
Family
ID=74570355
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022508564A Pending JP2022544246A (ja) | 2019-08-13 | 2020-08-13 | 修飾された多量体二環式ペプチドリガンド |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US20220275053A1 (https=) |
| EP (1) | EP4013501A1 (https=) |
| JP (1) | JP2022544246A (https=) |
| CN (1) | CN114787197A (https=) |
| WO (1) | WO2021028686A1 (https=) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP6882978B2 (ja) | 2014-10-29 | 2021-06-02 | バイスクルアールディー・リミテッド | Ｍｔ１−ｍｍｐに特異的な二環性ペプチドリガンド |
| JP7301757B2 (ja) | 2017-06-26 | 2023-07-03 | バイスクルアールディー・リミテッド | 検出可能部分を持つ二環式ペプチドリガンドおよびその使用 |
| CN111183147B (zh) | 2017-08-04 | 2024-07-05 | 拜斯科技术开发有限公司 | Cd137特异性的双环肽配体 |
| TWI825046B (zh) | 2017-12-19 | 2023-12-11 | 英商拜西可泰克斯有限公司 | Epha2特用之雙環胜肽配位基 |
| JP2021514953A (ja) | 2018-02-23 | 2021-06-17 | バイスクルテクス・リミテッド | 多量体二環式ペプチドリガンド |
| IL279489B2 (en) | 2018-06-22 | 2025-10-01 | Bicycletx Ltd | Bicyclic peptide ligands specific for nectin-4, a drug conjugate containing the peptide ligands and a pharmaceutical composition containing the drug conjugate |
| GB201820295D0 (en) | 2018-12-13 | 2019-01-30 | Bicyclerd Ltd | Bicyclic peptide ligands specific for MT1-MMP |
| GB201820288D0 (en) | 2018-12-13 | 2019-01-30 | Bicycle Tx Ltd | Bicycle peptide ligaands specific for MT1-MMP |
| GB201820325D0 (en) | 2018-12-13 | 2019-01-30 | Bicyclerd Ltd | Bicyclic peptide ligands specific for psma |
| US12551567B2 (en) | 2018-12-21 | 2026-02-17 | Bicyclerd Limited | Bicyclic peptide ligands specific for PD-L1 |
| JP2022514618A (ja) | 2018-12-21 | 2022-02-14 | バイスクルテクス・リミテッド | Ｐｄ－ｌ１に特異的な二環式ペプチドリガンド |
| GB201900529D0 (en) | 2019-01-15 | 2019-03-06 | Bicycletx Ltd | Bicyclic peptide ligands specific for CD38 |
| TWI860386B (zh) | 2019-07-30 | 2024-11-01 | 英商拜西可泰克斯有限公司 | 異質雙環肽複合物 |
| ES3033517T3 (en) * | 2019-10-03 | 2025-08-05 | Bicycletx Ltd | Heterotandem bicyclic peptide complexes |
| IL300248A (en) | 2020-08-03 | 2023-03-01 | Bicycletx Ltd | peptide-based linkers |
| GB202016331D0 (en) * | 2020-10-15 | 2020-12-02 | Bicyclerd Ltd | Bicyclic peptide ligand drug conjugates |
| US20250186539A2 (en) * | 2021-01-11 | 2025-06-12 | Bicycletx Limited | Methods for treating cancer |
| EP4308586A1 (en) * | 2021-03-19 | 2024-01-24 | BicycleTX Limited | Bicyclic peptide ligands specific for trem2 |
| MX2024003876A (es) | 2021-09-29 | 2024-04-19 | Conjustar Zhuhai Biologics Co Ltd | Conjugado farmaco-polipeptido triciclico y sus aplicaciones. |
| CN114133434B (zh) * | 2021-12-01 | 2022-11-15 | 北京大学第一医院 | 靶向Nectin-4的双环肽核素配体与探针 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1452868A2 (en) | 2003-02-27 | 2004-09-01 | Pepscan Systems B.V. | Method for selecting a candidate drug compound |
| DK1844337T3 (da) | 2005-01-24 | 2013-09-30 | Pepscan Systems Bv | Bindingsforbindelser, immunogene forbindelser og peptidmimetika |
| JP4030067B2 (ja) * | 2005-03-22 | 2008-01-09 | ロート製薬株式会社 | 新規ペプチド |
| AU2009211253B2 (en) | 2008-02-05 | 2014-11-06 | Bicyclerd Limited | Methods and compositions |
| EP3181146A1 (en) * | 2015-12-16 | 2017-06-21 | Ruprecht-Karls-Universität Heidelberg | Cyclic ntcp-targeting peptides and their uses as entry inhibitors |
| TWI825046B (zh) * | 2017-12-19 | 2023-12-11 | 英商拜西可泰克斯有限公司 | Epha2特用之雙環胜肽配位基 |
| JP2021514953A (ja) * | 2018-02-23 | 2021-06-17 | バイスクルテクス・リミテッド | 多量体二環式ペプチドリガンド |
| JP7551500B2 (ja) * | 2018-04-04 | 2024-09-17 | バイスクルテクス・リミテッド | ヘテロタンデム二環式ペプチド複合体 |
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2020
- 2020-08-13 WO PCT/GB2020/051923 patent/WO2021028686A1/en not_active Ceased
- 2020-08-13 JP JP2022508564A patent/JP2022544246A/ja active Pending
- 2020-08-13 EP EP20757655.4A patent/EP4013501A1/en not_active Withdrawn
- 2020-08-13 US US17/630,754 patent/US20220275053A1/en active Pending
- 2020-08-13 CN CN202080064375.8A patent/CN114787197A/zh active Pending