JP2022540768A - 骨髄細胞炎症性表現型を調節するための抗ｃｄ５３組成物及び方法、ならびにその使用 - Google Patents

骨髄細胞炎症性表現型を調節するための抗ｃｄ５３組成物及び方法、ならびにその使用 Download PDF

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JP2022540768A
JP2022540768A JP2021576605A JP2021576605A JP2022540768A JP 2022540768 A JP2022540768 A JP 2022540768A JP 2021576605 A JP2021576605 A JP 2021576605A JP 2021576605 A JP2021576605 A JP 2021576605A JP 2022540768 A JP2022540768 A JP 2022540768A
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cells
macrophages
bone marrow
antigen
agent
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JPWO2020263651A5 (zh
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ノボブランツェバ，タチアナ・アイ
フェルドマン，イゴル
サジンスキー，スティーブン・エル
ワーレ，ジョーセフ・エイ
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ヴェルソー セラピューティクス， インコーポレイテッド
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    • C07—ORGANIC CHEMISTRY
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    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2896—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against molecules with a "CD"-designation, not provided for elsewhere
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K39/461—Cellular immunotherapy characterised by the cell type used
    • A61K39/4614—Monocytes; Macrophages
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    • G01N33/5091—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing the pathological state of an organism
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    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56966—Animal cells
    • G01N33/56972—White blood cells
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    • G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57484—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites
    • G01N33/57488—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites involving compounds identifable in body fluids
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    • C07K2317/565—Complementarity determining region [CDR]
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JP2021576605A 2019-06-27 2020-06-17 骨髄細胞炎症性表現型を調節するための抗ｃｄ５３組成物及び方法、ならびにその使用 Pending JP2022540768A (ja)

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US201962867602P 2019-06-27 2019-06-27
US62/867,602 2019-06-27
PCT/US2020/038116 WO2020263651A1 (en) 2019-06-27 2020-06-17 Anti-cd53 compositions and methods for modulating myeloid cell inflammatory phenotypes and uses thereof

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JP2022540768A true JP2022540768A (ja) 2022-09-20
JPWO2020263651A5 JPWO2020263651A5 (zh) 2023-06-26

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US (1) US20220251233A1 (zh)
EP (1) EP3990015A4 (zh)
JP (1) JP2022540768A (zh)
KR (1) KR20220042128A (zh)
CN (1) CN114728057A (zh)
AU (1) AU2020304415A1 (zh)
BR (1) BR112021026181A2 (zh)
CA (1) CA3142840A1 (zh)
IL (1) IL289171A (zh)
WO (1) WO2020263651A1 (zh)

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KR102616360B1 (ko) * 2021-11-09 2023-12-27 재단법인 아산사회복지재단 염증성 근육병증 진단용 바이오마커 조성물
CN116380755B (zh) * 2023-03-20 2023-11-21 广州市第一人民医院（广州消化疾病中心、广州医科大学附属市一人民医院、华南理工大学附属第二医院） CD127+PMN-MDSCs在诊断支气管肺发育不良中的应用及诊断试剂盒

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WO1992001049A2 (en) * 1990-07-13 1992-01-23 The General Hospital Corporation Cd53 cell surface antigen and use thereof
US7674598B2 (en) * 2004-05-21 2010-03-09 Beckman Coulter, Inc. Method for a fully automated monoclonal antibody-based extended differential
CN101583722A (zh) * 2006-07-14 2009-11-18 阿维瓦生物科学股份有限公司 从生物学样品检测稀有细胞的方法和组合物
KR20190003951A (ko) * 2016-04-04 2019-01-10 바이오버라티브 유에스에이 인코포레이티드 항-보체 인자 bb 항체 및 이의 용도
TW202023629A (zh) * 2018-06-29 2020-07-01 美商維西歐製藥公司 用於調節單核球及巨噬細胞發炎表型之組合物及方法以及其免疫療法用途

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IL289171A (en) 2022-02-01
EP3990015A1 (en) 2022-05-04
AU2020304415A1 (en) 2022-02-17
KR20220042128A (ko) 2022-04-04
BR112021026181A2 (pt) 2022-02-15
EP3990015A4 (en) 2023-04-26
WO2020263651A1 (en) 2020-12-30
CN114728057A (zh) 2022-07-08
US20220251233A1 (en) 2022-08-11
CA3142840A1 (en) 2020-12-30

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