JP2022538467A - 生体適合性増粘ポリマーおよびキトサン誘導体を含む生体適合性組成物 - Google Patents

生体適合性増粘ポリマーおよびキトサン誘導体を含む生体適合性組成物 Download PDF

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JP2022538467A
JP2022538467A JP2021578100A JP2021578100A JP2022538467A JP 2022538467 A JP2022538467 A JP 2022538467A JP 2021578100 A JP2021578100 A JP 2021578100A JP 2021578100 A JP2021578100 A JP 2021578100A JP 2022538467 A JP2022538467 A JP 2022538467A
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biocompatible
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biocompatible composition
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chitosan derivative
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JP2022538467A5 (https=
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トラヴァン・アンドレア
ボルゴーニャ・マッシミリアノ・アントニオ
パッラヴィチーニ・マッテオ
デ・ロリス・アンジェロ
シッカルディ・フランチェスコ
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メダクタ・インターナショナル・ソシエテ・アノニム
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/28—Materials for coating prostheses
    • A61L27/34—Macromolecular materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14—Macromolecular materials
    • A61L27/26—Mixtures of macromolecular compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/54—Biologically active materials, e.g. therapeutic substances
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/0006—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid
    • C08B37/0024—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid beta-D-Glucans; (beta-1,3)-D-Glucans, e.g. paramylon, coriolan, sclerotan, pachyman, callose, scleroglucan, schizophyllan, laminaran, lentinan or curdlan; (beta-1,6)-D-Glucans, e.g. pustulan; (beta-1,4)-D-Glucans; (beta-1,3)(beta-1,4)-D-Glucans, e.g. lichenan; Derivatives thereof
    • C08B37/0027—2-Acetamido-2-deoxy-beta-glucans; Derivatives thereof
    • C08B37/003—Chitin, i.e. 2-acetamido-2-deoxy-(beta-1,4)-D-glucan or N-acetyl-beta-1,4-D-glucosamine; Chitosan, i.e. deacetylated product of chitin or (beta-1,4)-D-glucosamine; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L1/00—Compositions of cellulose, modified cellulose or cellulose derivatives
    • C08L1/08—Cellulose derivatives
    • C08L1/26—Cellulose ethers
    • C08L1/28—Alkyl ethers
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L1/00—Compositions of cellulose, modified cellulose or cellulose derivatives
    • C08L1/08—Cellulose derivatives
    • C08L1/26—Cellulose ethers
    • C08L1/28—Alkyl ethers
    • C08L1/284—Alkyl ethers with hydroxylated hydrocarbon radicals
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L5/00—Compositions of polysaccharides or of their derivatives not provided for in groups C08L1/00 or C08L3/00
    • C08L5/08—Chitin; Chondroitin sulfate; Hyaluronic acid; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/10—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing inorganic materials
    • A61L2300/102—Metals or metal compounds, e.g. salts such as bicarbonates, carbonates, oxides, zeolites, silicates
    • A61L2300/104—Silver, e.g. silver sulfadiazine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/404—Biocides, antimicrobial agents, antiseptic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/60—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a special physical form
    • A61L2300/62—Encapsulated active agents, e.g. emulsified droplets
    • A61L2300/624—Nanocapsules
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2420/00—Materials or methods for coatings medical devices
    • A61L2420/02—Methods for coating medical devices
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2430/00—Materials or treatment for tissue regeneration
    • A61L2430/24—Materials or treatment for tissue regeneration for joint reconstruction
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08K—Use of inorganic or non-macromolecular organic substances as compounding ingredients
    • C08K3/00—Use of inorganic substances as compounding ingredients
    • C08K3/02—Elements
    • C08K3/08—Metals
    • C08K2003/0806—Silver
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08K—Use of inorganic or non-macromolecular organic substances as compounding ingredients
    • C08K3/00—Use of inorganic substances as compounding ingredients
    • C08K3/02—Elements
    • C08K3/08—Metals
    • C08K2003/085—Copper
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08K—Use of inorganic or non-macromolecular organic substances as compounding ingredients
    • C08K3/00—Use of inorganic substances as compounding ingredients
    • C08K3/02—Elements
    • C08K3/08—Metals
    • C08K2003/0893—Zinc
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08K—Use of inorganic or non-macromolecular organic substances as compounding ingredients
    • C08K2201/00—Specific properties of additives
    • C08K2201/011—Nanostructured additives

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Dermatology (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Transplantation (AREA)
  • Epidemiology (AREA)
  • Polymers & Plastics (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • Materials Engineering (AREA)
  • Materials For Medical Uses (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
  • Biological Depolymerization Polymers (AREA)
JP2021578100A 2019-07-02 2020-07-02 生体適合性増粘ポリマーおよびキトサン誘導体を含む生体適合性組成物 Pending JP2022538467A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
IT102019000010740A IT201900010740A1 (it) 2019-07-02 2019-07-02 Biocompatible compositions comprising a biocompatible thickening polymer and a chitosan derivative
IT102019000010740 2019-07-02
PCT/EP2020/068733 WO2021001507A1 (en) 2019-07-02 2020-07-02 Biocompatible compositions comprising a biocompatible thickening polymer and a chitosan derivative

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JP2022538467A true JP2022538467A (ja) 2022-09-02
JP2022538467A5 JP2022538467A5 (https=) 2023-08-21

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JP2021578100A Pending JP2022538467A (ja) 2019-07-02 2020-07-02 生体適合性増粘ポリマーおよびキトサン誘導体を含む生体適合性組成物

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US (1) US12440602B2 (https=)
EP (1) EP3994182A1 (https=)
JP (1) JP2022538467A (https=)
AU (1) AU2020300016B2 (https=)
IT (1) IT201900010740A1 (https=)
WO (1) WO2021001507A1 (https=)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2024214274A1 (ja) * 2023-04-14 2024-10-17 Ｓｍａｒｔ Ｔｉｓｓｕｅｓ株式会社 化学修飾された多糖類を含むポリマー材料

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR102852787B1 (ko) * 2021-12-28 2025-08-28 단국대학교 천안캠퍼스 산학협력단 신규한 화합물을 포함하는 생리 식염수
WO2025073823A1 (en) * 2023-10-03 2025-04-10 Aarhus Universitet Antioxidant microgels for liver diseases

Citations (6)

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JP2007504920A (ja) * 2003-05-16 2007-03-08 ブルー メンブレーンス ゲーエムベーハー 生体適合性コーティングされた医療用インプラント
JP2007537005A (ja) * 2004-05-12 2007-12-20 サーモディクス，インコーポレイティド 医療用具のための天然生分解性多糖コーティング
JP2009517488A (ja) * 2005-11-10 2009-04-30 アレジャンス・コーポレーション 抗菌コーティングを備えたエラストマー製品
JP2009537268A (ja) * 2006-05-22 2009-10-29 ユニヴァーシタ デグリ ステュディ デイ トリエステ 組織工学用で活性化合物のキャリアとしての、多糖類混合物のハイドロゲル
JP2009537597A (ja) * 2006-05-22 2009-10-29 ユニヴァーシタ デグリ ステュディ デイ トリエステ アニオン性及びカチオン性多糖類のポリマー混合物並びにその使用
JP2011528746A (ja) * 2008-07-23 2011-11-24 ユニヴァーシタ デグリ ステュディ デイ トリエステ 多糖マトリックス及び金属ナノ粒子からなる三次元ナノ複合材料、並びにその調製及び使用

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US4424346A (en) 1981-06-04 1984-01-03 Canadian Patents And Development Ltd. Derivatives of chitins, chitosans and other polysaccharides
IT1391668B1 (it) 2008-07-23 2012-01-17 Universita' Degli Studi Di Trieste Materiali nanocompositi basati su nanoparticelle metalliche stabilizzate con polisaccaridi a struttura ramificata.
EP2213315A1 (en) 2009-01-30 2010-08-04 Mero S.r.L. Antibacterial hydrogel and use thereof in orthopedics
CA3027969A1 (en) * 2016-06-16 2017-12-21 Eye Care International, Llc Compositions and methods of treating dry eye syndrome and other traumatized non-keratinized epithelial surfaces
IT201600130342A1 (it) 2016-12-22 2018-06-22 Biopolife S R L Addotti solubili di acido borico o suoi derivati e precursori con derivati oligosaccaridici del chitosano

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2007504920A (ja) * 2003-05-16 2007-03-08 ブルー メンブレーンス ゲーエムベーハー 生体適合性コーティングされた医療用インプラント
JP2007537005A (ja) * 2004-05-12 2007-12-20 サーモディクス，インコーポレイティド 医療用具のための天然生分解性多糖コーティング
JP2009517488A (ja) * 2005-11-10 2009-04-30 アレジャンス・コーポレーション 抗菌コーティングを備えたエラストマー製品
JP2009537268A (ja) * 2006-05-22 2009-10-29 ユニヴァーシタ デグリ ステュディ デイ トリエステ 組織工学用で活性化合物のキャリアとしての、多糖類混合物のハイドロゲル
JP2009537597A (ja) * 2006-05-22 2009-10-29 ユニヴァーシタ デグリ ステュディ デイ トリエステ アニオン性及びカチオン性多糖類のポリマー混合物並びにその使用
JP2011528746A (ja) * 2008-07-23 2011-11-24 ユニヴァーシタ デグリ ステュディ デイ トリエステ 多糖マトリックス及び金属ナノ粒子からなる三次元ナノ複合材料、並びにその調製及び使用

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2024214274A1 (ja) * 2023-04-14 2024-10-17 Ｓｍａｒｔ Ｔｉｓｓｕｅｓ株式会社 化学修飾された多糖類を含むポリマー材料

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Publication number Publication date
IT201900010740A1 (it) 2021-01-02
EP3994182A1 (en) 2022-05-11
AU2020300016B2 (en) 2026-02-05
WO2021001507A1 (en) 2021-01-07
AU2020300016A1 (en) 2022-01-20
US20220313868A1 (en) 2022-10-06
US12440602B2 (en) 2025-10-14

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