IT201900010740A1 - Biocompatible compositions comprising a biocompatible thickening polymer and a chitosan derivative - Google Patents

Biocompatible compositions comprising a biocompatible thickening polymer and a chitosan derivative Download PDF

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Publication number
IT201900010740A1
IT201900010740A1 IT102019000010740A IT201900010740A IT201900010740A1 IT 201900010740 A1 IT201900010740 A1 IT 201900010740A1 IT 102019000010740 A IT102019000010740 A IT 102019000010740A IT 201900010740 A IT201900010740 A IT 201900010740A IT 201900010740 A1 IT201900010740 A1 IT 201900010740A1
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IT
Italy
Prior art keywords
composition
equal
biocompatible
composition according
weight
Prior art date
Application number
IT102019000010740A
Other languages
English (en)
Italian (it)
Inventor
Andrea Travan
Massimiliano Antonio Borgogna
Matteo Parravicini
Lollis Angelo De
Francesco Siccardi
Original Assignee
Medacta Int Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Medacta Int Sa filed Critical Medacta Int Sa
Priority to IT102019000010740A priority Critical patent/IT201900010740A1/it
Priority to PCT/EP2020/068733 priority patent/WO2021001507A1/en
Priority to EP20735597.5A priority patent/EP3994182A1/en
Priority to US17/597,280 priority patent/US12440602B2/en
Priority to JP2021578100A priority patent/JP2022538467A/ja
Priority to AU2020300016A priority patent/AU2020300016B2/en
Publication of IT201900010740A1 publication Critical patent/IT201900010740A1/it

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/28—Materials for coating prostheses
    • A61L27/34—Macromolecular materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14—Macromolecular materials
    • A61L27/26—Mixtures of macromolecular compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/54—Biologically active materials, e.g. therapeutic substances
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/0006—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid
    • C08B37/0024—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid beta-D-Glucans; (beta-1,3)-D-Glucans, e.g. paramylon, coriolan, sclerotan, pachyman, callose, scleroglucan, schizophyllan, laminaran, lentinan or curdlan; (beta-1,6)-D-Glucans, e.g. pustulan; (beta-1,4)-D-Glucans; (beta-1,3)(beta-1,4)-D-Glucans, e.g. lichenan; Derivatives thereof
    • C08B37/0027—2-Acetamido-2-deoxy-beta-glucans; Derivatives thereof
    • C08B37/003—Chitin, i.e. 2-acetamido-2-deoxy-(beta-1,4)-D-glucan or N-acetyl-beta-1,4-D-glucosamine; Chitosan, i.e. deacetylated product of chitin or (beta-1,4)-D-glucosamine; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L1/00—Compositions of cellulose, modified cellulose or cellulose derivatives
    • C08L1/08—Cellulose derivatives
    • C08L1/26—Cellulose ethers
    • C08L1/28—Alkyl ethers
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L1/00—Compositions of cellulose, modified cellulose or cellulose derivatives
    • C08L1/08—Cellulose derivatives
    • C08L1/26—Cellulose ethers
    • C08L1/28—Alkyl ethers
    • C08L1/284—Alkyl ethers with hydroxylated hydrocarbon radicals
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L5/00—Compositions of polysaccharides or of their derivatives not provided for in groups C08L1/00 or C08L3/00
    • C08L5/08—Chitin; Chondroitin sulfate; Hyaluronic acid; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/10—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing inorganic materials
    • A61L2300/102—Metals or metal compounds, e.g. salts such as bicarbonates, carbonates, oxides, zeolites, silicates
    • A61L2300/104—Silver, e.g. silver sulfadiazine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/404—Biocides, antimicrobial agents, antiseptic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/60—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a special physical form
    • A61L2300/62—Encapsulated active agents, e.g. emulsified droplets
    • A61L2300/624—Nanocapsules
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2420/00—Materials or methods for coatings medical devices
    • A61L2420/02—Methods for coating medical devices
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2430/00—Materials or treatment for tissue regeneration
    • A61L2430/24—Materials or treatment for tissue regeneration for joint reconstruction
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08K—Use of inorganic or non-macromolecular organic substances as compounding ingredients
    • C08K3/00—Use of inorganic substances as compounding ingredients
    • C08K3/02—Elements
    • C08K3/08—Metals
    • C08K2003/0806—Silver
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08K—Use of inorganic or non-macromolecular organic substances as compounding ingredients
    • C08K3/00—Use of inorganic substances as compounding ingredients
    • C08K3/02—Elements
    • C08K3/08—Metals
    • C08K2003/085—Copper
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08K—Use of inorganic or non-macromolecular organic substances as compounding ingredients
    • C08K3/00—Use of inorganic substances as compounding ingredients
    • C08K3/02—Elements
    • C08K3/08—Metals
    • C08K2003/0893—Zinc
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08K—Use of inorganic or non-macromolecular organic substances as compounding ingredients
    • C08K2201/00—Specific properties of additives
    • C08K2201/011—Nanostructured additives

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Dermatology (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Transplantation (AREA)
  • Epidemiology (AREA)
  • Polymers & Plastics (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • Materials Engineering (AREA)
  • Materials For Medical Uses (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
  • Biological Depolymerization Polymers (AREA)
IT102019000010740A 2019-07-02 2019-07-02 Biocompatible compositions comprising a biocompatible thickening polymer and a chitosan derivative IT201900010740A1 (it)

Priority Applications (6)

Application Number Priority Date Filing Date Title
IT102019000010740A IT201900010740A1 (it) 2019-07-02 2019-07-02 Biocompatible compositions comprising a biocompatible thickening polymer and a chitosan derivative
PCT/EP2020/068733 WO2021001507A1 (en) 2019-07-02 2020-07-02 Biocompatible compositions comprising a biocompatible thickening polymer and a chitosan derivative
EP20735597.5A EP3994182A1 (en) 2019-07-02 2020-07-02 Biocompatible compositions comprising a biocompatible thickening polymer and a chitosan derivative
US17/597,280 US12440602B2 (en) 2019-07-02 2020-07-02 Biocompatible compositions comprising a biocompatible thickening polymer and a chitosan derivative
JP2021578100A JP2022538467A (ja) 2019-07-02 2020-07-02 生体適合性増粘ポリマーおよびキトサン誘導体を含む生体適合性組成物
AU2020300016A AU2020300016B2 (en) 2019-07-02 2020-07-02 Biocompatible compositions comprising a biocompatible thickening polymer and a chitosan derivative

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT102019000010740A IT201900010740A1 (it) 2019-07-02 2019-07-02 Biocompatible compositions comprising a biocompatible thickening polymer and a chitosan derivative

Publications (1)

Publication Number Publication Date
IT201900010740A1 true IT201900010740A1 (it) 2021-01-02

Family

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Family Applications (1)

Application Number Title Priority Date Filing Date
IT102019000010740A IT201900010740A1 (it) 2019-07-02 2019-07-02 Biocompatible compositions comprising a biocompatible thickening polymer and a chitosan derivative

Country Status (6)

Country Link
US (1) US12440602B2 (https=)
EP (1) EP3994182A1 (https=)
JP (1) JP2022538467A (https=)
AU (1) AU2020300016B2 (https=)
IT (1) IT201900010740A1 (https=)
WO (1) WO2021001507A1 (https=)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR102852787B1 (ko) * 2021-12-28 2025-08-28 단국대학교 천안캠퍼스 산학협력단 신규한 화합물을 포함하는 생리 식염수
JPWO2024214274A1 (https=) * 2023-04-14 2024-10-17
WO2025073823A1 (en) * 2023-10-03 2025-04-10 Aarhus Universitet Antioxidant microgels for liver diseases

Citations (8)

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Publication number Priority date Publication date Assignee Title
US4424346A (en) 1981-06-04 1984-01-03 Canadian Patents And Development Ltd. Derivatives of chitins, chitosans and other polysaccharides
US20050255142A1 (en) 2004-05-12 2005-11-17 Surmodics, Inc. Coatings for medical articles including natural biodegradable polysaccharides
WO2007135114A1 (en) * 2006-05-22 2007-11-29 Universita' Degli Studi Di Trieste Hydrogels of polysaccharide mixtures for tissue engineering and as carriers of active compounds
WO2007135116A1 (en) * 2006-05-22 2007-11-29 Universita' Degli Studi Di Trieste Polymer mixtures of anionic and cationic polysaccharides and use thereof
WO2010010123A1 (en) * 2008-07-23 2010-01-28 Universita' Degli Studi Di Trieste Three-dimensional nanocomposite materials consisting of a polysaccharidic matrix and metallic nanoparticles, preparation and use thereof
WO2010086421A1 (en) 2009-01-30 2010-08-05 Mero S.R.L. Antibacterial hydrogel and use thereof in orthopedics
US20110129536A1 (en) 2008-07-23 2011-06-02 Universita Degli Studi Di Trieste Nanocomposite materials based on metallic nanoparticles stabilized with branched polysaccharides
WO2018116224A1 (en) 2016-12-22 2018-06-28 Biopolife Srl Soluble adducts of boric acid or derivatives and precursors thereof with chitosan oligosaccharide derivatives

Family Cites Families (3)

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Publication number Priority date Publication date Assignee Title
EP1626752A2 (de) 2003-05-16 2006-02-22 Blue Membranes GmbH Biokompatibel beschichtete medizinische implantate
US8137735B2 (en) * 2005-11-10 2012-03-20 Allegiance Corporation Elastomeric article with antimicrobial coating
CA3027969A1 (en) * 2016-06-16 2017-12-21 Eye Care International, Llc Compositions and methods of treating dry eye syndrome and other traumatized non-keratinized epithelial surfaces

Patent Citations (9)

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US4424346A (en) 1981-06-04 1984-01-03 Canadian Patents And Development Ltd. Derivatives of chitins, chitosans and other polysaccharides
US20050255142A1 (en) 2004-05-12 2005-11-17 Surmodics, Inc. Coatings for medical articles including natural biodegradable polysaccharides
WO2007135114A1 (en) * 2006-05-22 2007-11-29 Universita' Degli Studi Di Trieste Hydrogels of polysaccharide mixtures for tissue engineering and as carriers of active compounds
WO2007135116A1 (en) * 2006-05-22 2007-11-29 Universita' Degli Studi Di Trieste Polymer mixtures of anionic and cationic polysaccharides and use thereof
WO2010010123A1 (en) * 2008-07-23 2010-01-28 Universita' Degli Studi Di Trieste Three-dimensional nanocomposite materials consisting of a polysaccharidic matrix and metallic nanoparticles, preparation and use thereof
US20110123589A1 (en) 2008-07-23 2011-05-26 Universita Degil Studi di Trieste Three-dimensional nanocomposite materials consisting of a polysaccharidic matrix and metallic nanoparticles, preparation and use thereof
US20110129536A1 (en) 2008-07-23 2011-06-02 Universita Degli Studi Di Trieste Nanocomposite materials based on metallic nanoparticles stabilized with branched polysaccharides
WO2010086421A1 (en) 2009-01-30 2010-08-05 Mero S.R.L. Antibacterial hydrogel and use thereof in orthopedics
WO2018116224A1 (en) 2016-12-22 2018-06-28 Biopolife Srl Soluble adducts of boric acid or derivatives and precursors thereof with chitosan oligosaccharide derivatives

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Also Published As

Publication number Publication date
EP3994182A1 (en) 2022-05-11
AU2020300016B2 (en) 2026-02-05
WO2021001507A1 (en) 2021-01-07
JP2022538467A (ja) 2022-09-02
AU2020300016A1 (en) 2022-01-20
US20220313868A1 (en) 2022-10-06
US12440602B2 (en) 2025-10-14

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