JP2022537684A - 分泌された微生物細胞外小胞 - Google Patents

分泌された微生物細胞外小胞 Download PDF

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JP2022537684A
JP2022537684A JP2021573416A JP2021573416A JP2022537684A JP 2022537684 A JP2022537684 A JP 2022537684A JP 2021573416 A JP2021573416 A JP 2021573416A JP 2021573416 A JP2021573416 A JP 2021573416A JP 2022537684 A JP2022537684 A JP 2022537684A
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pharmaceutical composition
smev
cancer
smevs
disease
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JP2022537684A5 (enExample
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バロック，アリシア
ボドマー，マーク
ボーズ，バウンダウナ
エム．アール． カールトン，ソフィア
エー． コーマック，テイラー
ジェイ．エイチ． デイヴィット，クリストファー
フランシスコ－アンダーソン，ルイーズ
グッドマン，ブライアン
イタノ，アンドレア
オカン，ニハル
ポニクテラ，ホーリー
ビー． トロイ，エリン
ビー． ロマノ－チャーナック，ファビアン
シゾヴァ，マリア
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エヴェロ バイオサイエンシズ，インコーポレーテッド
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66—Microorganisms or materials therefrom
    • A61K35/74—Bacteria
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66—Microorganisms or materials therefrom
    • A61K35/74—Bacteria
    • A61K35/741—Probiotics
    • A61K35/744—Lactic acid bacteria, e.g. enterococci, pediococci, lactococci, streptococci or leuconostocs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66—Microorganisms or materials therefrom
    • A61K35/74—Bacteria
    • A61K35/741—Probiotics
    • A61K35/744—Lactic acid bacteria, e.g. enterococci, pediococci, lactococci, streptococci or leuconostocs
    • A61K35/745—Bifidobacteria
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K2035/11—Medicinal preparations comprising living procariotic cells
    • A61K2035/115—Probiotics
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Immunology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
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  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Transplantation (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Physiology (AREA)
  • Nutrition Science (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
JP2021573416A 2019-06-11 2020-06-11 分泌された微生物細胞外小胞 Pending JP2022537684A (ja)

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
US201962860049P 2019-06-11 2019-06-11
US201962860029P 2019-06-11 2019-06-11
US62/860,029 2019-06-11
US62/860,049 2019-06-11
US202062979545P 2020-02-21 2020-02-21
US62/979,545 2020-02-21
US202062991767P 2020-03-19 2020-03-19
US62/991,767 2020-03-19
PCT/US2020/037201 WO2020252144A1 (en) 2019-06-11 2020-06-11 Secreted microbial extracellular vesicles

Publications (2)

Publication Number Publication Date
JP2022537684A true JP2022537684A (ja) 2022-08-29
JP2022537684A5 JP2022537684A5 (enExample) 2023-06-15

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JP2021573416A Pending JP2022537684A (ja) 2019-06-11 2020-06-11 分泌された微生物細胞外小胞
JP2021573327A Pending JP2022538765A (ja) 2019-06-11 2020-06-11 処理された微生物細胞外小胞

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US (2) US20220249579A1 (enExample)
EP (2) EP3982987A1 (enExample)
JP (2) JP2022537684A (enExample)
KR (2) KR20220020893A (enExample)
CN (2) CN114096262A (enExample)
AU (2) AU2020291003A1 (enExample)
BR (2) BR112021024830A2 (enExample)
CA (2) CA3143036A1 (enExample)
CO (2) CO2022000040A2 (enExample)
MX (2) MX2021015429A (enExample)
TW (2) TW202114718A (enExample)
WO (2) WO2020252149A1 (enExample)

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JP2024167772A (ja) * 2023-05-22 2024-12-04 マイクロアルジェコーポレーション株式会社 免疫賦活用組成物及び発現誘導用組成物

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US11090341B2 (en) * 2018-02-06 2021-08-17 Evelo Biosciences, Inc. Compositions and methods for treating cancer and immune disorders using Veillonella bacteria
KR102286042B1 (ko) * 2019-01-09 2021-08-03 주식회사 엠디헬스케어 데이노코커스 속 세균 유래 나노소포 및 이의 용도
JP7761556B2 (ja) * 2019-09-18 2025-10-28 リサーチ ディベロップメント ファウンデーション 代謝性疾患および障害を治療するための方法およびプロバイオティック組成物
TW202214276A (zh) * 2020-06-11 2022-04-16 美商艾弗洛生物科技股份有限公司 使用ｈａｒｒｙｆｌｉｎｔｉａ ａｃｅｔｉｓｐｏｒａ治療疾病和障礙之組成物及方法
WO2021252861A1 (en) * 2020-06-11 2021-12-16 Evelo Biosciences, Inc. Compositions and methods for treating diseases and disorders using megasphaera sp
AU2021296649A1 (en) * 2020-06-22 2023-02-09 Sl Bigen, Inc. Method and composition for enhancing cancer treatment efficacy of bacteria extracellular vesicles
CN116249540A (zh) * 2020-07-21 2023-06-09 伊夫罗生物科学公司 小韦荣氏球菌菌株作为神经炎性疾病的口服疗法
TW202227110A (zh) * 2020-09-21 2022-07-16 美商艾弗洛生物科技股份有限公司 用棲組織普雷沃菌調節免疫反應之組成物及方法
US20240423924A1 (en) * 2021-01-26 2024-12-26 Evelo Biosciences, Inc. Prevotella extracellular vesicle preparations
WO2022178209A1 (en) * 2021-02-19 2022-08-25 Evelo Biosciences, Inc. Compositions and methods for treating metabolic diseases and disorders using christensenellaceae bacteria
WO2022221183A1 (en) * 2021-04-12 2022-10-20 Evelo Biosciences, Inc. Fournierella extracellular vesicle preparations
WO2022251166A2 (en) * 2021-05-25 2022-12-01 Evelo Biosciences, Inc. Bacterial compositions comprising soy hemoglobin
CN117440819A (zh) * 2021-06-07 2024-01-23 Md保健株式会社 包含明串珠菌属细菌来源的囊泡的用于预防或治疗炎性疾病或癌症的组合物
WO2023114300A1 (en) * 2021-12-14 2023-06-22 Evelo Biosciences, Inc. Fournierella massiliensis bacteria extracellular vesicle preparations
WO2023114293A1 (en) * 2021-12-14 2023-06-22 Evelo Biosciences, Inc. Extracellular vesicle assays
WO2023146843A1 (en) * 2022-01-25 2023-08-03 Evelo Biosciences, Inc. Extracellular vesicle compositions and methods of use
WO2023239728A1 (en) * 2022-06-07 2023-12-14 Evelo Biosciences, Inc. Compositions and methods of treating inflammation using prevotella histicola extracellular vesicles
CN118006515B (zh) * 2024-04-08 2024-06-18 中国农业大学 一株乳酸乳球菌及其在制备治疗牛乳腺炎的药物中的应用

Citations (3)

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WO2019051381A1 (en) * 2017-09-08 2019-03-14 Evelo Biosciences, Inc. EXTRACELLULAR VESICLES FROM PREVOTELLA
WO2019051380A1 (en) * 2017-09-08 2019-03-14 Evelo Biosciences, Inc. BACTERIAL EXTRACELLULAR (EV) VESICLES
WO2019099682A1 (en) * 2017-11-15 2019-05-23 Evelo Biosciences, Inc. Compositions and methods for treating immune disorders using immune modulating lactococcus bacteria strains

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KR102394638B1 (ko) * 2015-09-30 2022-05-09 (주)아모레퍼시픽 유산균 유래의 세포외 소낭을 포함하는 탈모 방지 또는 육모 촉진용 조성물
KR101858840B1 (ko) * 2016-01-15 2018-05-16 단국대학교 천안캠퍼스 산학협력단 집먼지진드기 유래 알레르겐에 의한 과민반응 면역조절제
KR102563191B1 (ko) * 2017-07-05 2023-08-02 에벨로 바이오사이언시즈, 인크. 비피도박테리움 애니멀리스 ssp. 락티스를 이용한 암 치료 조성물 및 방법
TW201920648A (zh) * 2017-08-29 2019-06-01 美商艾弗洛生物科技股份有限公司 使用布勞特氏(blautia)菌株治療癌症
CN111601610A (zh) * 2017-11-14 2020-08-28 伊夫罗生物科学公司 使用布劳特氏菌属菌株治疗疾病的组合物和方法
CN109580960A (zh) * 2019-01-14 2019-04-05 周明 细胞外囊泡的分离方法、以及检测细胞外囊泡表面标志物的方法和试剂盒

Patent Citations (3)

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WO2019051381A1 (en) * 2017-09-08 2019-03-14 Evelo Biosciences, Inc. EXTRACELLULAR VESICLES FROM PREVOTELLA
WO2019051380A1 (en) * 2017-09-08 2019-03-14 Evelo Biosciences, Inc. BACTERIAL EXTRACELLULAR (EV) VESICLES
WO2019099682A1 (en) * 2017-11-15 2019-05-23 Evelo Biosciences, Inc. Compositions and methods for treating immune disorders using immune modulating lactococcus bacteria strains

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2024167772A (ja) * 2023-05-22 2024-12-04 マイクロアルジェコーポレーション株式会社 免疫賦活用組成物及び発現誘導用組成物
JP7856958B2 (ja) 2023-05-22 2026-05-12 マイクロアルジェコーポレーション株式会社 免疫賦活用組成物及び発現誘導用組成物

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CN114650831A (zh) 2022-06-21
JP2022538765A (ja) 2022-09-06
AU2020291003A1 (en) 2022-01-06
US20220249579A1 (en) 2022-08-11
EP3982986A1 (en) 2022-04-20
AU2020291434A1 (en) 2022-01-06
WO2020252144A1 (en) 2020-12-17
TW202114718A (zh) 2021-04-16
KR20220020894A (ko) 2022-02-21
CA3143036A1 (en) 2020-12-17
CA3143025A1 (en) 2020-12-17
MX2021015427A (es) 2022-01-24
WO2020252149A1 (en) 2020-12-17
BR112021024830A2 (pt) 2022-04-12
CN114096262A (zh) 2022-02-25
EP3982987A1 (en) 2022-04-20
TW202128198A (zh) 2021-08-01
BR112021024754A2 (pt) 2022-04-19
KR20220020893A (ko) 2022-02-21
CO2022000040A2 (es) 2022-01-17
US20220296654A1 (en) 2022-09-22
CO2022000041A2 (es) 2022-01-17
MX2021015429A (es) 2022-01-24

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