JP2022535410A5 - - Google Patents

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Publication number
JP2022535410A5
JP2022535410A5 JP2021571870A JP2021571870A JP2022535410A5 JP 2022535410 A5 JP2022535410 A5 JP 2022535410A5 JP 2021571870 A JP2021571870 A JP 2021571870A JP 2021571870 A JP2021571870 A JP 2021571870A JP 2022535410 A5 JP2022535410 A5 JP 2022535410A5
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JP
Japan
Prior art keywords
amino acid
seq
acid sequence
taci
cdr
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2021571870A
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English (en)
Japanese (ja)
Other versions
JP7584453B2 (ja
JP2022535410A (ja
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Priority claimed from PCT/US2020/036108 external-priority patent/WO2020247618A1/en
Publication of JP2022535410A publication Critical patent/JP2022535410A/ja
Publication of JP2022535410A5 publication Critical patent/JP2022535410A5/ja
Application granted granted Critical
Publication of JP7584453B2 publication Critical patent/JP7584453B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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JP2021571870A 2019-06-04 2020-06-04 Taciを標的とする抗体及びキメラ抗原受容体 Active JP7584453B2 (ja)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US201962856998P 2019-06-04 2019-06-04
US62/856,998 2019-06-04
US201962907930P 2019-09-30 2019-09-30
US62/907,930 2019-09-30
US202063012735P 2020-04-20 2020-04-20
US63/012,735 2020-04-20
PCT/US2020/036108 WO2020247618A1 (en) 2019-06-04 2020-06-04 Antibodies and chimeric antigen receptors that target taci

Publications (3)

Publication Number Publication Date
JP2022535410A JP2022535410A (ja) 2022-08-08
JP2022535410A5 true JP2022535410A5 (https=) 2023-06-13
JP7584453B2 JP7584453B2 (ja) 2024-11-15

Family

ID=73652958

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2021571870A Active JP7584453B2 (ja) 2019-06-04 2020-06-04 Taciを標的とする抗体及びキメラ抗原受容体

Country Status (7)

Country Link
US (1) US12595303B2 (https=)
EP (1) EP3980454A4 (https=)
JP (1) JP7584453B2 (https=)
CN (1) CN114206919B (https=)
AU (1) AU2020287626A1 (https=)
CA (1) CA3139057A1 (https=)
WO (1) WO2020247618A1 (https=)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2020247618A1 (en) 2019-06-04 2020-12-10 The General Hospital Corporation Antibodies and chimeric antigen receptors that target taci
US20240245772A1 (en) * 2021-05-19 2024-07-25 Celledit Llc Bi-specific chimeric antigen receptors and genetically engineered immune cells expressing such
WO2023178073A2 (en) * 2022-03-15 2023-09-21 Celledit Llc Use of antigen presenting cells to enhance car-t cell therapy
WO2024056009A1 (zh) * 2022-09-14 2024-03-21 荣昌生物制药(烟台)股份有限公司 一种taci抗体及其用途
WO2024102067A1 (en) * 2022-11-08 2024-05-16 Agency For Science, Technology And Research Antigen binding protein specific for transmembrane activator and caml interactor (taci)
CN117288933A (zh) * 2023-09-21 2023-12-26 桂林医学院附属医院 检测car-t细胞杀伤力的方法

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7083950B2 (en) * 1998-09-25 2006-08-01 Regeneron Pharmaceuticals, Inc. High affinity fusion proteins and therapeutic and diagnostic methods for use
WO2002066516A2 (en) 2001-02-20 2002-08-29 Zymogenetics, Inc. Antibodies that bind both bcma and taci
WO2004011611A2 (en) 2002-07-25 2004-02-05 Genentech, Inc. Taci antibodies and uses thereof
WO2004074511A1 (en) * 2003-02-21 2004-09-02 Garvan Institute Of Medical Research Diagnosis and treatment of baff-mediated autoimmune diseases and cancer
EP2130552B1 (en) * 2007-02-27 2016-06-15 Chugai Seiyaku Kabushiki Kaisha Pharmaceutical composition comprising anti-grp78 antibody as active ingredient
CA2939411A1 (en) * 2014-02-27 2015-09-03 Ucl Business Plc Ligand
WO2018028647A1 (en) 2016-08-10 2018-02-15 Legend Biotech Usa Inc. Chimeric antigen receptors targeting bcma and methods of use thereof
EP3340995A4 (en) * 2015-08-28 2019-04-03 The Trustees Of The University Of Pennsylvania METHOD AND COMPOSITIONS FOR CELLS FOR EXPRESSING A CHIMERIC INTRA-CELLULAR SIGNAL MOLECULE
JP2019535262A (ja) * 2016-11-11 2019-12-12 オートラス リミテッド キメラ抗原受容体
CN108490174B (zh) 2018-04-18 2022-06-24 上海尚珞生物医药科技有限公司 检测car-t细胞的方法及其应用
WO2020247618A1 (en) 2019-06-04 2020-12-10 The General Hospital Corporation Antibodies and chimeric antigen receptors that target taci

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