JP2022533137A5 - - Google Patents
Info
- Publication number
- JP2022533137A5 JP2022533137A5 JP2021568292A JP2021568292A JP2022533137A5 JP 2022533137 A5 JP2022533137 A5 JP 2022533137A5 JP 2021568292 A JP2021568292 A JP 2021568292A JP 2021568292 A JP2021568292 A JP 2021568292A JP 2022533137 A5 JP2022533137 A5 JP 2022533137A5
- Authority
- JP
- Japan
- Prior art keywords
- tumor
- allele
- sample
- locus
- fraction
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201962850474P | 2019-05-20 | 2019-05-20 | |
| US62/850,474 | 2019-05-20 | ||
| PCT/US2020/033821 WO2020236941A1 (en) | 2019-05-20 | 2020-05-20 | Systems and methods for evaluating tumor fraction |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2022533137A JP2022533137A (ja) | 2022-07-21 |
| JP2022533137A5 true JP2022533137A5 (https=) | 2023-05-30 |
| JP7702360B2 JP7702360B2 (ja) | 2025-07-03 |
Family
ID=73458622
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021568292A Active JP7702360B2 (ja) | 2019-05-20 | 2020-05-20 | 腫瘍分率を評価するためのシステムおよび方法 |
Country Status (11)
| Country | Link |
|---|---|
| US (2) | US20220243279A1 (https=) |
| EP (1) | EP3973530A4 (https=) |
| JP (1) | JP7702360B2 (https=) |
| KR (1) | KR20220011140A (https=) |
| CN (1) | CN114026646A (https=) |
| AU (2) | AU2020279752A1 (https=) |
| BR (1) | BR112021022879A2 (https=) |
| CA (1) | CA3140066A1 (https=) |
| IL (1) | IL288182A (https=) |
| SG (1) | SG11202111947PA (https=) |
| WO (1) | WO2020236941A1 (https=) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES3022582T3 (en) | 2013-05-10 | 2025-05-28 | Found Medicine Inc | Analysis of genetic variants |
| JP2023552391A (ja) * | 2020-12-03 | 2023-12-15 | ファウンデーション・メディシン・インコーポレイテッド | 治療を選択し、予想される治療転帰を判定するための木ベースのモデル |
| EP4266315A4 (en) * | 2020-12-16 | 2024-11-20 | Seedna Inc. | METHOD FOR CALCULATING THE RELIABILITY VALUE OF A POLYMORPHISM LOCUS SIGNAL |
| CN113025716A (zh) * | 2021-03-02 | 2021-06-25 | 北京大学第一医院 | 一种用于人肿瘤分级的基因组合及其用途 |
| WO2022271159A1 (en) * | 2021-06-22 | 2022-12-29 | Foundation Medicine, Inc. | Systems and methods for evaluating tumor fraction |
| EP4374376A4 (en) * | 2021-07-23 | 2025-05-28 | Foundation Medicine, Inc. | METHODS FOR DETERMINING VARIANT FREQUENCY AND MONITORING DISEASE PROGRESSION |
| JP2024538725A (ja) * | 2021-10-08 | 2024-10-23 | ファウンデーション・メディシン・インコーポレイテッド | コピー数変化呼び出しに対する汚染を検出及び除去するための方法及びシステム |
| EP4430614A4 (en) * | 2021-11-12 | 2025-12-17 | Found Medicine Inc | Circulating tumor DNA fraction and uses thereof |
| WO2023096658A1 (en) * | 2021-11-23 | 2023-06-01 | Foundation Medicine, Inc. | Methods and systems for reporting clinically-actionable potential germline pathogenic variant sequences |
| US20250037823A1 (en) | 2021-12-08 | 2025-01-30 | Foundation Medicine, Inc. | Methods and systems for highlighting clinical information in diagnostic reports |
| CN114530200B (zh) * | 2022-03-18 | 2022-09-23 | 北京阅微基因技术股份有限公司 | 基于计算snp熵值的混合样本鉴定方法 |
| CN119585730A (zh) * | 2022-07-15 | 2025-03-07 | 基金会医学公司 | 用于确定患者样品中循环肿瘤dna分数的方法和系统 |
| WO2024081859A2 (en) * | 2022-10-14 | 2024-04-18 | Foundation Medicine, Inc. | Methods and systems for performing genomic variant calls based on identified off-target sequence reads |
| WO2024112967A1 (en) * | 2022-11-27 | 2024-05-30 | The University Of Chicago | Methods for treating cancer with immunotherapy |
| EP4631049A4 (en) * | 2022-12-09 | 2026-02-18 | Found Medicine Inc | METHODS AND SYSTEMS FOR DETERMINING THE CLONALITY OF SOMATIC SHORT VARIANTS |
| CN121219428A (zh) * | 2023-05-15 | 2025-12-26 | 基金会医学公司 | 用于评定液体活检样品中循环肿瘤dna分数的方法和系统 |
| WO2024238750A2 (en) * | 2023-05-17 | 2024-11-21 | Foundation Medicine, Inc. | Clonal hematopoiesis burden as a biomarker for immune checkpoint inhibitor response |
| WO2025054202A1 (en) | 2023-09-05 | 2025-03-13 | Sana Biotechnology, Inc. | Method of screening a sample comprising a transgene with a unique barcode |
| WO2025151838A1 (en) | 2024-01-12 | 2025-07-17 | Sana Biotechnology, Inc. | Safety switches to control in vitro and in vivo proliferation of cell therapy products |
| CN121305088B (zh) * | 2025-12-09 | 2026-03-17 | 中国人民解放军空军军医大学 | 迁移学习驱动的颅内肿瘤影像数据全自动分割方法 |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20110301854A1 (en) * | 2010-06-08 | 2011-12-08 | Curry Bo U | Method of Determining Allele-Specific Copy Number of a SNP |
| WO2014014498A1 (en) * | 2012-07-20 | 2014-01-23 | Verinata Health, Inc. | Detecting and classifying copy number variation in a fetal genome |
| US11261494B2 (en) * | 2012-06-21 | 2022-03-01 | The Chinese University Of Hong Kong | Method of measuring a fractional concentration of tumor DNA |
| CA2945962C (en) * | 2014-04-21 | 2023-08-29 | Natera, Inc. | Detecting mutations and ploidy in chromosomal segments |
| WO2015164432A1 (en) * | 2014-04-21 | 2015-10-29 | Natera, Inc. | Detecting mutations and ploidy in chromosomal segments |
| HUE058263T2 (hu) * | 2015-02-10 | 2022-07-28 | Univ Hong Kong Chinese | Mutációk detektálása rákszûrési és magzatelemzési célból |
| BR112018005940A2 (pt) * | 2015-09-25 | 2018-12-11 | Contextual Genomics Inc | métodos de garantia da qualidade molecular para uso em sequenciamento |
| CN114959918A (zh) * | 2016-02-29 | 2022-08-30 | 基础医疗股份有限公司 | 用于评估肿瘤突变负荷的方法和系统 |
| CA3067419A1 (en) * | 2017-06-20 | 2018-12-27 | Illumina, Inc. | Methods and systems for decomposition and quantification of dna mixtures from multiple contributors of known or unknown genotypes |
| JP7760242B2 (ja) * | 2017-07-21 | 2025-10-27 | ジェネンテック， インコーポレイテッド | がんの治療法及び診断法 |
-
2020
- 2020-05-20 CN CN202080037877.1A patent/CN114026646A/zh active Pending
- 2020-05-20 US US17/612,966 patent/US20220243279A1/en active Pending
- 2020-05-20 SG SG11202111947PA patent/SG11202111947PA/en unknown
- 2020-05-20 KR KR1020217040903A patent/KR20220011140A/ko active Pending
- 2020-05-20 EP EP20810118.8A patent/EP3973530A4/en active Pending
- 2020-05-20 CA CA3140066A patent/CA3140066A1/en active Pending
- 2020-05-20 BR BR112021022879A patent/BR112021022879A2/pt unknown
- 2020-05-20 WO PCT/US2020/033821 patent/WO2020236941A1/en not_active Ceased
- 2020-05-20 JP JP2021568292A patent/JP7702360B2/ja active Active
- 2020-05-20 AU AU2020279752A patent/AU2020279752A1/en not_active Abandoned
-
2021
- 2021-11-17 IL IL288182A patent/IL288182A/en unknown
-
2025
- 2025-04-04 US US19/171,081 patent/US20250259709A1/en active Pending
- 2025-11-27 AU AU2025271452A patent/AU2025271452A1/en active Pending
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