JP2022529390A - 汗検体測定値を補正するためのシステム及び方法 - Google Patents
汗検体測定値を補正するためのシステム及び方法 Download PDFInfo
- Publication number
- JP2022529390A JP2022529390A JP2021571946A JP2021571946A JP2022529390A JP 2022529390 A JP2022529390 A JP 2022529390A JP 2021571946 A JP2021571946 A JP 2021571946A JP 2021571946 A JP2021571946 A JP 2021571946A JP 2022529390 A JP2022529390 A JP 2022529390A
- Authority
- JP
- Japan
- Prior art keywords
- sweat
- temperature
- flow rate
- exhaust port
- capillaries
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Images
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01K—MEASURING TEMPERATURE; MEASURING QUANTITY OF HEAT; THERMALLY-SENSITIVE ELEMENTS NOT OTHERWISE PROVIDED FOR
- G01K13/00—Thermometers specially adapted for specific purposes
- G01K13/20—Clinical contact thermometers for use with humans or animals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
- A61B5/14507—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue specially adapted for measuring characteristics of body fluids other than blood
- A61B5/14517—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue specially adapted for measuring characteristics of body fluids other than blood for sweat
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
- A61B5/1486—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using enzyme electrodes, e.g. with immobilised oxidase
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/72—Signal processing specially adapted for physiological signals or for diagnostic purposes
- A61B5/7271—Specific aspects of physiological measurement analysis
- A61B5/7278—Artificial waveform generation or derivation, e.g. synthesising signals from measured signals
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01K—MEASURING TEMPERATURE; MEASURING QUANTITY OF HEAT; THERMALLY-SENSITIVE ELEMENTS NOT OTHERWISE PROVIDED FOR
- G01K17/00—Measuring quantity of heat
- G01K17/02—Calorimeters using transport of an indicating substances, e.g. evaporation calorimeters
- G01K17/025—Calorimeters using transport of an indicating substances, e.g. evaporation calorimeters where evaporation, sublimation or condensation caused by heating or cooling, is measured
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01K—MEASURING TEMPERATURE; MEASURING QUANTITY OF HEAT; THERMALLY-SENSITIVE ELEMENTS NOT OTHERWISE PROVIDED FOR
- G01K7/00—Measuring temperature based on the use of electric or magnetic elements directly sensitive to heat ; Power supply therefor, e.g. using thermoelectric elements
- G01K7/16—Measuring temperature based on the use of electric or magnetic elements directly sensitive to heat ; Power supply therefor, e.g. using thermoelectric elements using resistive elements
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B2560/00—Constructional details of operational features of apparatus; Accessories for medical measuring apparatus
- A61B2560/02—Operational features
- A61B2560/0242—Operational features adapted to measure environmental factors, e.g. temperature, pollution
- A61B2560/0247—Operational features adapted to measure environmental factors, e.g. temperature, pollution for compensation or correction of the measured physiological value
- A61B2560/0252—Operational features adapted to measure environmental factors, e.g. temperature, pollution for compensation or correction of the measured physiological value using ambient temperature
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B2560/00—Constructional details of operational features of apparatus; Accessories for medical measuring apparatus
- A61B2560/04—Constructional details of apparatus
- A61B2560/0406—Constructional details of apparatus specially shaped apparatus housings
- A61B2560/0412—Low-profile patch shaped housings
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Physics & Mathematics (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Pathology (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Heart & Thoracic Surgery (AREA)
- Medical Informatics (AREA)
- Biophysics (AREA)
- Surgery (AREA)
- Veterinary Medicine (AREA)
- Optics & Photonics (AREA)
- General Physics & Mathematics (AREA)
- Chemical & Material Sciences (AREA)
- Physiology (AREA)
- Signal Processing (AREA)
- Computer Vision & Pattern Recognition (AREA)
- Artificial Intelligence (AREA)
- Psychiatry (AREA)
- Combustion & Propulsion (AREA)
- Urology & Nephrology (AREA)
- Medicinal Chemistry (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- Food Science & Technology (AREA)
- Immunology (AREA)
- Hematology (AREA)
- Measuring And Recording Apparatus For Diagnosis (AREA)
Abstract
Description
代替的に「マイクロ流体チャネル」と呼ばれる毛細管108が一杯になった後、過剰な汗は、排気口110からの汗の蒸発により取り除かれ、これが毛細管108の流れを促進する。
Claims (15)
- 温度依存性の汗検体測定値を補正するためのシステムにおいて、前記システムは、
皮膚から汗を収集するための汗収集器、
前記汗が蒸発することができる排気口、
前記汗収集器から前記排気口に前記汗を送るための毛細管、
前記毛細管を通る前記汗の流量を測定するための流量センサ、
前記汗から前記汗検体測定値を得るための検体センサ、及び
制御器
を有し、前記制御器は、
前記測定される流量から温度を決定し、及び
前記決定される温度に基づいて、前記汗検体測定値を補正する
ように構成される、システム。 - 前記汗収集器、前記毛細管、前記排気口、前記流量センサ及び前記検体センサは、皮膚に付けるためのパッチ内に少なくとも一部が収容される、請求項1に記載のシステム。
- 前記パッチは、皮膚と、前記毛細管、前記排気口、前記流量センサ及び前記検体センサとの間で熱を伝えるように配される熱伝導層を含む、請求項2に記載のシステム。
- 前記パッチは、前記毛細管、前記排気口、前記流量センサ及び前記検体センサを皮膚から断熱するように配される断熱層を含む、請求項2に記載のシステム。
- 前記汗収集器、前記毛細管、前記排気口、前記流量センサ及び前記検体センサがその中に置かれる前記パッチの厚さは、10mm未満、好ましくは5mm未満である、請求項2乃至4の何れか一項に記載のシステム。
- 前記排気口から前記蒸発した汗を受け取るための蒸気受け取りチャンバを有し、前記蒸気受け取りチャンバは、前記排気口を周囲空気の流れから保護するように、前記排気口に対して配される、請求項1乃至5の何れか一項に記載のシステム。
- 前記蒸気受け取りチャンバは、
前記蒸発した汗を大気中に逃がすための通気口、及び
ある期間にわたり、前記蒸気受け取りチャンバ内の湿度レベルを維持するための蒸気受け取りチャンバ内にある乾燥剤
を有する、請求項6に記載のシステム。 - 前記多孔質体を有し、前記多孔質体の孔が前記排気口を画定する、請求項1乃至7の何れか一項に記載のシステム。
- 前記多孔質体は、多孔質膜の形態をとっている、請求項8に記載のシステム。
- 前記制御器は、前記温度と前記流量との間における既定の相関関係を使用して、前記測定される流量から前記温度を決定するように構成される、請求項1乃至9の何れか一項に記載のシステム。
- 前記既定の相関関係は、ルックアップテーブルの形態である、請求項10に記載のシステム。
- 前記制御器は、
前記測定される流量から発汗速度を決定し、及び
前記決定される発汗速度に基づいて前記汗検体測定値を補正する
ようにさらに構成される、請求項1乃至11の何れか一項に記載のシステム。 - 前記補正される汗検体測定値をユーザに通信するための出力装置を有する、請求項1乃至12の何れか一項に記載のシステム。
- 温度依存性の汗検体測定値を補正するための方法において、前記方法は、
汗を収集し、前記汗を毛細管を介して排気口に供給するステップであって、前記汗は、毛細管作用及び前記排気口からの前記汗の蒸発により、前記毛細管を介して取り出される、前記供給するステップ、
前記毛細管を通る前記汗の流量を測定するステップ、
前記測定される流量から温度を決定するステップ、
前記汗から汗検体測定値を得るステップ、及び
前記決定される温度に基づいて、前記汗検体測定値を補正するステップ
を有する方法。 - 前記測定される流量から温度を決定するステップは、前記温度と前記流量との間における既定の相関関係を使用するステップを有する、請求項14に記載の方法。
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP19182520.7 | 2019-06-26 | ||
EP19182520.7A EP3756544A1 (en) | 2019-06-26 | 2019-06-26 | System and method for correcting a sweat analyte measurement |
PCT/EP2020/066846 WO2020260107A1 (en) | 2019-06-26 | 2020-06-18 | System and method for correcting a sweat analyte measurement |
Publications (2)
Publication Number | Publication Date |
---|---|
JP2022529390A true JP2022529390A (ja) | 2022-06-21 |
JP7199579B2 JP7199579B2 (ja) | 2023-01-05 |
Family
ID=67070730
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2021571946A Active JP7199579B2 (ja) | 2019-06-26 | 2020-06-18 | 汗検体測定値を補正するためのシステム及び方法 |
Country Status (5)
Country | Link |
---|---|
US (1) | US20220313123A1 (ja) |
EP (2) | EP3756544A1 (ja) |
JP (1) | JP7199579B2 (ja) |
CN (1) | CN114424036A (ja) |
WO (1) | WO2020260107A1 (ja) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP7477932B2 (ja) | 2021-03-19 | 2024-05-02 | 国立研究開発法人物質・材料研究機構 | 熱中症、脱水症予兆警告システムおよび蒸散速度計測用デバイス |
CN113288224A (zh) * | 2021-04-27 | 2021-08-24 | 中国人民解放军南部战区总医院 | 一种虹吸式汗液富集收集装置 |
CN117085258B (zh) * | 2023-10-09 | 2024-03-08 | 广州瑞能精准医学科技有限公司 | 一种红外线加热型汗液刺激及采集装置 |
Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20180263539A1 (en) * | 2015-09-28 | 2018-09-20 | The Regents Of The University Of California | Wearable sensor arrays for in-situ body fluid analysis |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR20110041579A (ko) * | 2003-08-15 | 2011-04-21 | 애니머스 테크놀로지스 엘엘씨 | 생리적 분석물의 모니터링용 마이크로프로세서, 장치, 및 방법 |
EP3242112B1 (en) * | 2016-05-04 | 2019-09-18 | CSEM Centre Suisse D'electronique Et De Microtechnique SA | Method and device for measurement of liquid flow rate |
-
2019
- 2019-06-26 EP EP19182520.7A patent/EP3756544A1/en not_active Withdrawn
-
2020
- 2020-06-18 US US17/617,024 patent/US20220313123A1/en active Pending
- 2020-06-18 EP EP20733280.0A patent/EP3989821B1/en active Active
- 2020-06-18 WO PCT/EP2020/066846 patent/WO2020260107A1/en unknown
- 2020-06-18 JP JP2021571946A patent/JP7199579B2/ja active Active
- 2020-06-18 CN CN202080046458.4A patent/CN114424036A/zh active Pending
Patent Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20180263539A1 (en) * | 2015-09-28 | 2018-09-20 | The Regents Of The University Of California | Wearable sensor arrays for in-situ body fluid analysis |
Non-Patent Citations (6)
Title |
---|
ALLAN J. R. ET AL.: ""Influence of acclimatization on sweat sodium concentration"", JOURNAL OF APPLIED PHYSIOLOGY, vol. 30, no. 5, JPN6022017268, 31 May 1971 (1971-05-31), pages 708 - 712, ISSN: 0004764284 * |
NIE CHUAN ET AL.: "" A microfluidic device based on an evaporation-driven micropump"", BIOMEDICAL MICRODEVICES, vol. 17, no. 47, JPN6022017265, 25 March 2015 (2015-03-25), pages 1 - 12, XP035499142, ISSN: 0004764288, DOI: 10.1007/s10544-015-9948-7 * |
NYEIN HNIN YIN YIN ET AL.: ""A Wearable Microfluidic Sensing Patch for Dynamic Sweat Secretion Analysis"", ACS SENSORS, vol. 3, no. 5, JPN6022017261, 16 May 2018 (2018-05-16), pages 944 - 952, XP055525587, ISSN: 0004764283, DOI: 10.1021/acssensors.7b00961 * |
OGAI KAZUHIRO ET AL.: "" Development of a small wireless device for perspiration monitoring"", MEDICAL ENGINEERING & PHYSICS, vol. 38, no. 4, JPN6022017263, 30 April 2016 (2016-04-30), pages 391 - 397, XP029458082, ISSN: 0004764287, DOI: 10.1016/j.medengphy.2015.12.009 * |
SCHARF BRADLEY ALAN ET AL.: ""Regional differences in sweat rate response of steers to short-term heat stress"", INTERNATIONAL JOURNAL OF BIOMETEOROLOGY, vol. 52, no. 8, JPN6022017266, 30 November 2008 (2008-11-30), pages 725 - 732, XP019659097, ISSN: 0004764286, DOI: 10.1007/s00484-008-0165-4 * |
WILSON THAD E. ET AL: ""Mean body temperature dose not modulate eccrine sweat rate during upright tilt"", JOURNAL OF APPLIED PHYSIOLOGY, vol. 98, JPN6022017267, 3 December 2004 (2004-12-03), pages 1207 - 1212, ISSN: 0004764285 * |
Also Published As
Publication number | Publication date |
---|---|
JP7199579B2 (ja) | 2023-01-05 |
CN114424036A (zh) | 2022-04-29 |
EP3756544A1 (en) | 2020-12-30 |
EP3989821A1 (en) | 2022-05-04 |
US20220313123A1 (en) | 2022-10-06 |
EP3989821B1 (en) | 2022-09-28 |
WO2020260107A1 (en) | 2020-12-30 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
JP7199579B2 (ja) | 汗検体測定値を補正するためのシステム及び方法 | |
JP7177914B2 (ja) | 差動発汗測定のための方法及び装置 | |
Nyein et al. | A wearable patch for continuous analysis of thermoregulatory sweat at rest | |
Klous et al. | The (in) dependency of blood and sweat sodium, chloride, potassium, ammonia, lactate and glucose concentrations during submaximal exercise | |
Jin et al. | Identifying human body states by using a flexible integrated sensor | |
US20120095303A1 (en) | method for non-invasive blood glucose monitoring | |
Jain et al. | A mass-customizable dermal patch with discrete colorimetric indicators for personalized sweat rate quantification | |
JP6063488B2 (ja) | ガス濃度を決定するセンサ | |
Wijayanto et al. | Comparison of thermoregulatory responses to heat between Malaysian and Japanese males during leg immersion | |
Flouris et al. | Thermometry and calorimetry assessment of sweat response during exercise in the heat | |
EP3649941A1 (en) | Device, system and method for estimating an analyte concentration in sweat as released by a sweat gland | |
Li et al. | Regulation of sensory nerve conduction velocity of human bodies responding to annual temperature variations in natural environments | |
JP7486674B2 (ja) | 汗パラメータの決定 | |
Salvo | Wearable technologies for sweat rate and conductivity sensors: design and principles | |
US20230134870A1 (en) | Method of positioning a sweat sensor device | |
Uchida et al. | New portable device for continuous measurement of sweat rate under heat stress during field tests | |
Islam | Assistive sensing technology for the elderly health monitoring | |
Kanikowska et al. | Attenuated thermoregulatory responses with increased plasma osmolality in obese subjects during two seasons | |
Rescio et al. | Fully Integrated Smart Insole for Diabetic Foot | |
Rescio et al. | Smart insole for diabetic foot monitoring | |
Sivakumar et al. | WASP: Wearable Analytical Skin Probe for Dynamic Monitoring of Transepidermal Water Loss | |
Joshi et al. | Low cost thermal camera for use in preclinical detection of diabetic peripheral neuropathy in primary care setting | |
US20080239477A1 (en) | Observation system |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
A621 | Written request for application examination |
Free format text: JAPANESE INTERMEDIATE CODE: A621 Effective date: 20211203 |
|
A871 | Explanation of circumstances concerning accelerated examination |
Free format text: JAPANESE INTERMEDIATE CODE: A871 Effective date: 20211203 |
|
A131 | Notification of reasons for refusal |
Free format text: JAPANESE INTERMEDIATE CODE: A131 Effective date: 20220506 |
|
A601 | Written request for extension of time |
Free format text: JAPANESE INTERMEDIATE CODE: A601 Effective date: 20220802 |
|
A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20221031 |
|
TRDD | Decision of grant or rejection written | ||
A01 | Written decision to grant a patent or to grant a registration (utility model) |
Free format text: JAPANESE INTERMEDIATE CODE: A01 Effective date: 20221213 |
|
A61 | First payment of annual fees (during grant procedure) |
Free format text: JAPANESE INTERMEDIATE CODE: A61 Effective date: 20221220 |
|
R150 | Certificate of patent or registration of utility model |
Ref document number: 7199579 Country of ref document: JP Free format text: JAPANESE INTERMEDIATE CODE: R150 |