JP2022527322A5 - - Google Patents
Info
- Publication number
- JP2022527322A5 JP2022527322A5 JP2021558523A JP2021558523A JP2022527322A5 JP 2022527322 A5 JP2022527322 A5 JP 2022527322A5 JP 2021558523 A JP2021558523 A JP 2021558523A JP 2021558523 A JP2021558523 A JP 2021558523A JP 2022527322 A5 JP2022527322 A5 JP 2022527322A5
- Authority
- JP
- Japan
- Prior art keywords
- chimeric protein
- protein according
- optionally
- mutations
- amino acid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2025067565A JP2025111546A (ja) | 2019-03-28 | 2025-04-16 | Ｆｍｓ様チロシンキナーゼ３リガンド（ｆｌｔ３ｌ）ベースキメラタンパク質 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201962825579P | 2019-03-28 | 2019-03-28 | |
| US62/825,579 | 2019-03-28 | ||
| PCT/US2020/025419 WO2020198659A1 (en) | 2019-03-28 | 2020-03-27 | Fms-like tyrosine kinase 3 ligand (flt3l)-based chimeric proteins |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2025067565A Division JP2025111546A (ja) | 2019-03-28 | 2025-04-16 | Ｆｍｓ様チロシンキナーゼ３リガンド（ｆｌｔ３ｌ）ベースキメラタンパク質 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2022527322A JP2022527322A (ja) | 2022-06-01 |
| JP2022527322A5 true JP2022527322A5 (https=) | 2023-04-03 |
| JP7749186B2 JP7749186B2 (ja) | 2025-10-06 |
Family
ID=72608957
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021558523A Active JP7749186B2 (ja) | 2019-03-28 | 2020-03-27 | Ｆｍｓ様チロシンキナーゼ３リガンド（ｆｌｔ３ｌ）ベースキメラタンパク質 |
| JP2025067565A Pending JP2025111546A (ja) | 2019-03-28 | 2025-04-16 | Ｆｍｓ様チロシンキナーゼ３リガンド（ｆｌｔ３ｌ）ベースキメラタンパク質 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2025067565A Pending JP2025111546A (ja) | 2019-03-28 | 2025-04-16 | Ｆｍｓ様チロシンキナーゼ３リガンド（ｆｌｔ３ｌ）ベースキメラタンパク質 |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US20220185857A1 (https=) |
| EP (1) | EP3946409A4 (https=) |
| JP (2) | JP7749186B2 (https=) |
| CN (1) | CN113645988A (https=) |
| CA (1) | CA3133830A1 (https=) |
| WO (1) | WO2020198659A1 (https=) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP7773372B2 (ja) | 2019-03-28 | 2025-11-19 | オリオニス バイオサイエンシズ，インコーポレイテッド | 線維芽細胞活性化タンパク質結合物質およびその使用 |
| CN114606227B (zh) * | 2022-02-22 | 2024-03-08 | 复旦大学 | 高精度腺嘌呤碱基编辑器及其应用 |
| AU2024341598A1 (en) * | 2023-09-12 | 2026-04-23 | Heligenics Inc. | Engineered interferon-beta proteins |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7294331B2 (en) * | 1994-03-07 | 2007-11-13 | Immunex Corporation | Methods of using flt3-ligand in hematopoietic cell transplantation |
| US20020034517A1 (en) * | 1995-10-04 | 2002-03-21 | Kenneth Brasel | Dendritic cell stimulatory factor |
| PL333023A1 (en) * | 1996-10-25 | 1999-11-08 | Searle & Co | Chimerical antagonists of haeomogenic multifunctional receptors |
| US6660257B1 (en) * | 1996-10-25 | 2003-12-09 | Pharmacia Corporation | Circular permuteins of flt3 ligand |
| US6291661B1 (en) * | 1998-07-02 | 2001-09-18 | Immunex Corporation | flt3-L mutants and method of use |
| US20050232931A1 (en) * | 2003-06-13 | 2005-10-20 | Oncomax Acquisition Corp. | Preparation and application of anti-tumor bifunctional fusion proteins |
| JP2007515946A (ja) | 2003-06-13 | 2007-06-21 | オンコマックス アクイジション コーポレイション | 抗腫瘍二元機能融合タンパク質の調製および適用 |
| ES2694180T3 (es) * | 2012-01-20 | 2018-12-18 | Vib Vzw | Citocinas de haz alfa-helicoidal mutantes dirigidas |
| WO2015168474A1 (en) * | 2014-04-30 | 2015-11-05 | President And Fellows Of Harvard College | Fusion proteins for treating cancer and related methods |
| JP6898325B2 (ja) * | 2015-12-08 | 2021-07-07 | ユニバーシティ−インダストリー・ファンデーション・ヨンセイ・ユニバーシティ | ＧＭ−ＣＳＦ遺伝子；Ｆｌｔ３Ｌ−ＴＲＡＩＬ融合遺伝子；ＴＧＦ−βの発現を抑制するｓｈＲＮＡ；およびＨＳＰ発現を抑制するｓｈＲＮＡを含む抗腫瘍組成物 |
| EP3426278B1 (en) | 2016-03-07 | 2024-01-03 | Vib Vzw | Cd20 binding single domain antibodies |
-
2020
- 2020-03-27 WO PCT/US2020/025419 patent/WO2020198659A1/en not_active Ceased
- 2020-03-27 CA CA3133830A patent/CA3133830A1/en active Pending
- 2020-03-27 JP JP2021558523A patent/JP7749186B2/ja active Active
- 2020-03-27 EP EP20778984.3A patent/EP3946409A4/en active Pending
- 2020-03-27 CN CN202080025812.5A patent/CN113645988A/zh active Pending
- 2020-03-27 US US17/442,772 patent/US20220185857A1/en active Pending
-
2025
- 2025-04-16 JP JP2025067565A patent/JP2025111546A/ja active Pending
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