JP2022527189A5 - - Google Patents

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Publication number
JP2022527189A5
JP2022527189A5 JP2021557924A JP2021557924A JP2022527189A5 JP 2022527189 A5 JP2022527189 A5 JP 2022527189A5 JP 2021557924 A JP2021557924 A JP 2021557924A JP 2021557924 A JP2021557924 A JP 2021557924A JP 2022527189 A5 JP2022527189 A5 JP 2022527189A5
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JP
Japan
Prior art keywords
fgfr3
gene mutations
fgfr
fgfr gene
pharmaceutical composition
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2021557924A
Other languages
English (en)
Japanese (ja)
Other versions
JP7747521B2 (ja
JP2022527189A (ja
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Publication date
Application filed filed Critical
Priority claimed from PCT/US2020/025166 external-priority patent/WO2020205493A1/en
Publication of JP2022527189A publication Critical patent/JP2022527189A/ja
Publication of JP2022527189A5 publication Critical patent/JP2022527189A5/ja
Priority to JP2025072308A priority Critical patent/JP2025156297A/ja
Application granted granted Critical
Publication of JP7747521B2 publication Critical patent/JP7747521B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

JP2021557924A 2019-03-29 2020-03-27 尿路上皮癌の治療のためのfgfrチロシンキナーゼ阻害剤 Active JP7747521B2 (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2025072308A JP2025156297A (ja) 2019-03-29 2025-04-24 尿路上皮癌の治療のためのfgfrチロシンキナーゼ阻害剤

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
EP19166428.3 2019-03-29
EP19166428 2019-03-29
EP19188971 2019-07-30
EP19188971.6 2019-07-30
PCT/US2020/025166 WO2020205493A1 (en) 2019-03-29 2020-03-27 Fgfr tyrosine kinase inhibitors for the treatment of urothelial carcinoma

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2025072308A Division JP2025156297A (ja) 2019-03-29 2025-04-24 尿路上皮癌の治療のためのfgfrチロシンキナーゼ阻害剤

Publications (3)

Publication Number Publication Date
JP2022527189A JP2022527189A (ja) 2022-05-31
JP2022527189A5 true JP2022527189A5 (https=) 2023-04-03
JP7747521B2 JP7747521B2 (ja) 2025-10-01

Family

ID=70296138

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2021557924A Active JP7747521B2 (ja) 2019-03-29 2020-03-27 尿路上皮癌の治療のためのfgfrチロシンキナーゼ阻害剤
JP2025072308A Pending JP2025156297A (ja) 2019-03-29 2025-04-24 尿路上皮癌の治療のためのfgfrチロシンキナーゼ阻害剤

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2025072308A Pending JP2025156297A (ja) 2019-03-29 2025-04-24 尿路上皮癌の治療のためのfgfrチロシンキナーゼ阻害剤

Country Status (15)

Country Link
US (1) US20220054484A1 (https=)
EP (1) EP3946341A1 (https=)
JP (2) JP7747521B2 (https=)
KR (1) KR20210145211A (https=)
CN (1) CN113645974A (https=)
AU (1) AU2020253827B2 (https=)
BR (1) BR112021019446A2 (https=)
CA (1) CA3130460A1 (https=)
IL (1) IL286729A (https=)
JO (1) JOP20210266A1 (https=)
MA (1) MA55522A (https=)
MX (1) MX2021011926A (https=)
PH (1) PH12021552342A1 (https=)
SG (1) SG11202109902SA (https=)
WO (1) WO2020205493A1 (https=)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP4719420A1 (en) * 2023-05-24 2026-04-08 Janssen Pharmaceutica NV Treatment of locally advanced or metastatic urothelial carcinoma with erdafinitib

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4666828A (en) 1984-08-15 1987-05-19 The General Hospital Corporation Test for Huntington's disease
US4683202A (en) 1985-03-28 1987-07-28 Cetus Corporation Process for amplifying nucleic acid sequences
US4801531A (en) 1985-04-17 1989-01-31 Biotechnology Research Partners, Ltd. Apo AI/CIII genomic polymorphisms predictive of atherosclerosis
US5033252A (en) 1987-12-23 1991-07-23 Entravision, Inc. Method of packaging and sterilizing a pharmaceutical product
US5052558A (en) 1987-12-23 1991-10-01 Entravision, Inc. Packaged pharmaceutical product
US5272057A (en) 1988-10-14 1993-12-21 Georgetown University Method of detecting a predisposition to cancer by the use of restriction fragment length polymorphism of the gene for human poly (ADP-ribose) polymerase
US5192659A (en) 1989-08-25 1993-03-09 Genetype Ag Intron sequence analysis method for detection of adjacent and remote locus alleles as haplotypes
US5323907A (en) 1992-06-23 1994-06-28 Multi-Comp, Inc. Child resistant package assembly for dispensing pharmaceutical medications
EP0951541B1 (en) 1995-07-31 2005-11-30 Urocor, Inc. Biomarkers and targets for diagnosis, prognosis and management of prostate disease
US6218529B1 (en) 1995-07-31 2001-04-17 Urocor, Inc. Biomarkers and targets for diagnosis, prognosis and management of prostate, breast and bladder cancer
GB0512324D0 (en) 2005-06-16 2005-07-27 Novartis Ag Organic compounds
BRPI0611375A2 (pt) 2005-05-23 2010-08-31 Novartis Ag formas cristalinas e outras de sais de ácido láctico de 4-amino-5-flúor-3-[6-(4-metilpiperazin-1-il)-1h-benzimid azol-2-il]-1h-quinolin-2-ona
US8163923B2 (en) 2007-03-14 2012-04-24 Advenchen Laboratories, Llc Spiro substituted compounds as angiogenesis inhibitors
GB201007286D0 (en) 2010-04-30 2010-06-16 Astex Therapeutics Ltd New compounds
KR102470456B1 (ko) 2014-09-26 2022-11-23 얀센 파마슈티카 엔.브이. Fgfr 억제제를 사용한 치료에 반응할 암 환자를 확인하는 데 있어서 fgfr 돌연변이 유전자 패널의 사용
US10208024B2 (en) * 2015-10-23 2019-02-19 Array Biopharma Inc. 2-aryl- and 2-heteroaryl-substituted 2-pyridazin-3(2H)-one compounds as inhibitors of FGFR tyrosine kinases
HUE062453T2 (hu) 2017-02-06 2023-11-28 Janssen Pharmaceutica Nv Rákbetegség kezelése
SG11201906249PA (en) 2017-02-06 2019-08-27 Rainier Therapeutics Inc Methods, compositions, and kits for treatment of cancer
TWI798199B (zh) * 2017-02-06 2023-04-11 比利時商健生藥品公司 癌症治療
JOP20190280A1 (ar) * 2017-06-02 2019-12-02 Janssen Pharmaceutica Nv مثبطات fgfr2 لعلاج سرطان الأوعية الصفراوية

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