JP2022527054A - 吸入可能な乾燥粉末 - Google Patents

吸入可能な乾燥粉末 Download PDF

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Publication number
JP2022527054A
JP2022527054A JP2021556771A JP2021556771A JP2022527054A JP 2022527054 A JP2022527054 A JP 2022527054A JP 2021556771 A JP2021556771 A JP 2021556771A JP 2021556771 A JP2021556771 A JP 2021556771A JP 2022527054 A JP2022527054 A JP 2022527054A
Authority
JP
Japan
Prior art keywords
dry powder
inhaler
particles
pharmaceutical composition
diketopiperazine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2021556771A
Other languages
English (en)
Japanese (ja)
Other versions
JP2022527054A5 (enExample
Inventor
ジェイ．グアルネリ ジョセフ
シー．スマットニー チャド
Original Assignee
マンカインド コーポレイション
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by マンカインド コーポレイション filed Critical マンカインド コーポレイション
Publication of JP2022527054A publication Critical patent/JP2022527054A/ja
Publication of JP2022527054A5 publication Critical patent/JP2022527054A5/ja
Priority to JP2025002002A priority Critical patent/JP2025061049A/ja
Pending legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/658—Medicinal preparations containing organic active ingredients o-phenolic cannabinoids, e.g. cannabidiol, cannabigerolic acid, cannabichromene or tetrahydrocannabinol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0075—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a dry powder inhaler [DPI], e.g. comprising micronized drug mixed with lactose carrier particles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1617—Organic compounds, e.g. phospholipids, fats
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Otolaryngology (AREA)
  • Pulmonology (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
JP2021556771A 2019-03-22 2020-03-20 吸入可能な乾燥粉末 Pending JP2022527054A (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2025002002A JP2025061049A (ja) 2019-03-22 2025-01-06 吸入可能な乾燥粉末

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201962822303P 2019-03-22 2019-03-22
US62/822,303 2019-03-22
PCT/US2020/023977 WO2020198051A1 (en) 2019-03-22 2020-03-20 Inhalable dry powders

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2025002002A Division JP2025061049A (ja) 2019-03-22 2025-01-06 吸入可能な乾燥粉末

Publications (2)

Publication Number Publication Date
JP2022527054A true JP2022527054A (ja) 2022-05-30
JP2022527054A5 JP2022527054A5 (enExample) 2024-06-04

Family

ID=72608595

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2021556771A Pending JP2022527054A (ja) 2019-03-22 2020-03-20 吸入可能な乾燥粉末
JP2025002002A Pending JP2025061049A (ja) 2019-03-22 2025-01-06 吸入可能な乾燥粉末

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2025002002A Pending JP2025061049A (ja) 2019-03-22 2025-01-06 吸入可能な乾燥粉末

Country Status (6)

Country Link
US (1) US20220241271A1 (enExample)
EP (1) EP3941438A4 (enExample)
JP (2) JP2022527054A (enExample)
CA (1) CA3133804A1 (enExample)
MX (2) MX428309B (enExample)
WO (1) WO2020198051A1 (enExample)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP4120854A4 (en) * 2020-03-19 2024-03-27 TFF Pharmaceuticals, Inc. INHALATION OF DRIED PARTICLES FOR ADMINISTRATION OF CANNABIS
WO2022081814A1 (en) * 2020-10-16 2022-04-21 Michael Ogburn Inhalable cannabinoid formulations
CA3235985A1 (en) * 2021-10-27 2023-05-04 Mannkind Corporation Methods and compositions for treating pulmonary hypertension

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2009527583A (ja) * 2006-02-22 2009-07-30 マンカインド コーポレイション ジケトピペラジン及び活性薬剤を含有する微粒子の製剤特性の改善方法
JP2019504684A (ja) * 2016-01-29 2019-02-21 マンカインド コーポレイション 乾燥粉末吸入器

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE60017152D1 (de) * 1999-08-25 2005-02-03 Advanced Inhalation Res Inc Grosse poröse partikel erhältlich durch sprühtrocknung und geeignet zur pulmonalen anwendung
US20010036481A1 (en) * 1999-08-25 2001-11-01 Advanced Inhalation Research, Inc. Modulation of release from dry powder formulations
WO2006023703A2 (en) * 2004-08-20 2006-03-02 Cypress Bioscience, Inc. Method for treating sleep related breathing disorders
HUE025151T2 (en) * 2004-08-23 2016-01-28 Mannkind Corp Diceto-piperazine salts for drug delivery
MY155524A (en) * 2008-06-13 2015-10-30 Mannkind Corp A dry powder inhaler and system for drug delivery
PT2621488T (pt) * 2010-09-29 2019-02-12 Pulmatrix Operating Co Inc Pós secos catiónicos
UA125747C2 (uk) * 2015-09-01 2022-06-01 Фьост Вейв Байо, Інк. Способи та композиції для лікування станів, пов'язаних із аномальною запальною відповіддю

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2009527583A (ja) * 2006-02-22 2009-07-30 マンカインド コーポレイション ジケトピペラジン及び活性薬剤を含有する微粒子の製剤特性の改善方法
JP2019504684A (ja) * 2016-01-29 2019-02-21 マンカインド コーポレイション 乾燥粉末吸入器

Also Published As

Publication number Publication date
MX2021011491A (es) 2022-01-18
MX428309B (es) 2025-11-13
JP2025061049A (ja) 2025-04-10
EP3941438A1 (en) 2022-01-26
EP3941438A4 (en) 2022-09-21
CA3133804A1 (en) 2020-10-01
MX2025008306A (es) 2025-08-01
WO2020198051A1 (en) 2020-10-01
US20220241271A1 (en) 2022-08-04

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