JP2022525927A5 - - Google Patents
Info
- Publication number
- JP2022525927A5 JP2022525927A5 JP2021556491A JP2021556491A JP2022525927A5 JP 2022525927 A5 JP2022525927 A5 JP 2022525927A5 JP 2021556491 A JP2021556491 A JP 2021556491A JP 2021556491 A JP2021556491 A JP 2021556491A JP 2022525927 A5 JP2022525927 A5 JP 2022525927A5
- Authority
- JP
- Japan
- Prior art keywords
- cell
- cells
- polypeptide
- domain
- cell according
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201962820357P | 2019-03-19 | 2019-03-19 | |
| US62/820,357 | 2019-03-19 | ||
| PCT/IL2020/050327 WO2020188570A1 (en) | 2019-03-19 | 2020-03-19 | T cell expressing an fc gamma receptor and methods of use thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2022525927A JP2022525927A (ja) | 2022-05-20 |
| JP2022525927A5 true JP2022525927A5 (https=) | 2023-03-27 |
Family
ID=72519182
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021556491A Pending JP2022525927A (ja) | 2019-03-19 | 2020-03-19 | Fcガンマ受容体を発現するt細胞およびその使用方法 |
Country Status (8)
| Country | Link |
|---|---|
| US (2) | US20210401893A1 (https=) |
| EP (1) | EP3941492A4 (https=) |
| JP (1) | JP2022525927A (https=) |
| CN (1) | CN113853205A (https=) |
| AU (1) | AU2020243623A1 (https=) |
| CA (1) | CA3133037A1 (https=) |
| IL (1) | IL286477A (https=) |
| WO (1) | WO2020188570A1 (https=) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2023530182A (ja) | 2020-06-22 | 2023-07-13 | ラモット・アット・テル・アビブ・ユニバーシテイ・リミテッド | 多重サブユニットタンパク質モジュール、それを発現する細胞、及びその使用 |
| WO2024154122A1 (en) | 2023-01-18 | 2024-07-25 | Gilboa Therapeutics LTD | Immune cells expressing a complement receptor and uses thereof |
| WO2024236557A1 (en) | 2023-05-12 | 2024-11-21 | Gilboa Therapeutics LTD | Compositions comprising an fc domain for the treatment of medical conditions |
| CN117660500B (zh) * | 2023-09-28 | 2025-01-28 | 上海恩凯细胞技术有限公司 | 核酸构建体、载体、转基因免疫细胞及其应用 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5641875A (en) * | 1993-09-30 | 1997-06-24 | University Of Pennsylvania | DNA encoding chimeric IgG Fc receptor |
| AU2005277831B2 (en) * | 2004-07-10 | 2012-11-22 | The Institute For Cancer Research | Genetically modified human natural killer cell lines |
| US10144770B2 (en) * | 2013-10-17 | 2018-12-04 | National University Of Singapore | Chimeric receptors and uses thereof in immune therapy |
| US20170151283A1 (en) * | 2014-05-23 | 2017-06-01 | The Trustees Of The University Of Pennsylvania | Compositions and methods for treating antibody resistance |
| CA2972714A1 (en) * | 2014-09-09 | 2016-03-17 | Unum Therapeutics | Chimeric receptors and uses thereof in immune therapy |
| JP6839074B2 (ja) * | 2014-09-17 | 2021-03-03 | ノバルティス アーゲー | 養子免疫療法のためのキメラ受容体での細胞毒性細胞のターゲティング |
| US11440946B2 (en) * | 2015-03-13 | 2022-09-13 | University Of Maryland, Baltimore | Universal antibody-mediated biosensor |
-
2020
- 2020-03-19 JP JP2021556491A patent/JP2022525927A/ja active Pending
- 2020-03-19 WO PCT/IL2020/050327 patent/WO2020188570A1/en not_active Ceased
- 2020-03-19 CA CA3133037A patent/CA3133037A1/en active Pending
- 2020-03-19 EP EP20774261.0A patent/EP3941492A4/en not_active Withdrawn
- 2020-03-19 CN CN202080037294.9A patent/CN113853205A/zh active Pending
- 2020-03-19 AU AU2020243623A patent/AU2020243623A1/en not_active Abandoned
-
2021
- 2021-09-19 US US17/478,930 patent/US20210401893A1/en not_active Abandoned
- 2021-09-19 IL IL286477A patent/IL286477A/en unknown
-
2025
- 2025-01-03 US US19/008,721 patent/US20250163128A1/en active Pending
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| Sommermeyer et al. | Fully human CD19-specific chimeric antigen receptors for T-cell therapy | |
| Hombach et al. | A chimeric receptor that selectively targets membrane-bound carcinoembryonic antigen (mCEA) in the presence of soluble CEA | |
| US12076378B2 (en) | Use of car and bite technology coupled with an SCFV from an antibody against human thymidine kinase 1 to specifically target tumors | |
| D’Aloia et al. | CAR-T cells: the long and winding road to solid tumors | |
| JP7573441B2 (ja) | ガイダンス及びナビゲーションコントロール蛋白質並びにその生産及び使用方法 | |
| Hombach et al. | T cell activation by antibody-like immunoreceptors: the position of the binding epitope within the target molecule determines the efficiency of activation of redirected T cells | |
| JP2022525927A5 (https=) | ||
| KR102091297B1 (ko) | 항원-형질감염된 t 세포와 함께 사용되는 이중특이적 항체 분자 및 의약에서의 이들의 용도 | |
| Hombach et al. | T cell activation by recombinant FcεRI γ-chain immune receptors: an extracellular spacer domain impairs antigen-dependent T cell activation but not antigen recognition | |
| CN113698490B (zh) | 靶向cea的缺氧诱导启动的car结构及免疫细胞和应用 | |
| US20200093861A1 (en) | Antigen binding receptor formats | |
| JP2024023228A5 (https=) | ||
| EP4400516A1 (en) | Bispecific or-gate chimeric antigen receptor responsive to cd19 and cd20 | |
| JP2021529559A5 (https=) | ||
| CN111246861A (zh) | 扩增表达重组受体的细胞的试剂 | |
| JP2019527680A (ja) | 改善された養子t細胞療法 | |
| Pameijer et al. | Conversion of a tumor-binding peptide identified by phage display to a functional chimeric T cell antigen receptor | |
| Arndt et al. | Simultaneous targeting of prostate stem cell antigen and prostate‐specific membrane antigen improves the killing of prostate cancer cells using a novel modular T cell‐retargeting system | |
| CN115698081A (zh) | 靶向bcma的嵌合抗原受体及其用途 | |
| EP1413316A1 (en) | Bifunctional conjugates or fusion proteins | |
| JP2024540359A (ja) | Teamを分泌する抗メソテリンcart細胞とその使用方法 | |
| Heuser et al. | An anti-MUC1-antibody–interleukin-2 fusion protein that activates resting NK cells to lysis of MUC1-positive tumour cells | |
| JP2025540340A (ja) | キメラ抗原受容体 | |
| WO2025109493A1 (en) | Chimeric Receptors with Binding Capacity for Antibodies | |
| Saeed et al. | Recent advances in CAR-T cell therapy: From dual targeting to emerging innovations |