JP2022517827A - 生物学的サンプル中の分子効果に関連する分子変化を評価するための方法 - Google Patents

生物学的サンプル中の分子効果に関連する分子変化を評価するための方法 Download PDF

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JP2022517827A
JP2022517827A JP2021542097A JP2021542097A JP2022517827A JP 2022517827 A JP2022517827 A JP 2022517827A JP 2021542097 A JP2021542097 A JP 2021542097A JP 2021542097 A JP2021542097 A JP 2021542097A JP 2022517827 A JP2022517827 A JP 2022517827A
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biological sample
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JP2022517827A5 (enExample
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スタウバー，ジョナサン
アイト－ベルカセム，リマ
ボネル，ダヴィド
パムラール，ファビアン
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Imabiotech
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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G—PHYSICS
    • G06—COMPUTING OR CALCULATING; COUNTING
    • G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T7/00—Image analysis
    • G06T7/0002—Inspection of images, e.g. flaw detection
    • G06T7/0012—Biomedical image inspection
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2560/00—Chemical aspects of mass spectrometric analysis of biological material
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2570/00—Omics, e.g. proteomics, glycomics or lipidomics; Methods of analysis focusing on the entire complement of classes of biological molecules or subsets thereof, i.e. focusing on proteomes, glycomes or lipidomes
    • G—PHYSICS
    • G06—COMPUTING OR CALCULATING; COUNTING
    • G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T2207/00—Indexing scheme for image analysis or image enhancement
    • G06T2207/10—Image acquisition modality
    • G06T2207/10004—Still image; Photographic image
    • G—PHYSICS
    • G06—COMPUTING OR CALCULATING; COUNTING
    • G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T2207/00—Indexing scheme for image analysis or image enhancement
    • G06T2207/30—Subject of image; Context of image processing
    • G06T2207/30004—Biomedical image processing
    • G06T2207/30096—Tumor; Lesion

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  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biomedical Technology (AREA)
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  • Urology & Nephrology (AREA)
  • Molecular Biology (AREA)
  • Hematology (AREA)
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  • Computer Vision & Pattern Recognition (AREA)
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  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
JP2021542097A 2019-01-22 2020-01-21 生物学的サンプル中の分子効果に関連する分子変化を評価するための方法 Pending JP2022517827A (ja)

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EP19305081 2019-01-22
EP19305081.2 2019-01-22
PCT/EP2020/051388 WO2020152151A1 (en) 2019-01-22 2020-01-21 Method for evaluating molecular changes related to a molecule effect in a biological sample

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JP2022517827A true JP2022517827A (ja) 2022-03-10
JP2022517827A5 JP2022517827A5 (enExample) 2024-06-18

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US (1) US20220137027A1 (enExample)
EP (1) EP3914911A1 (enExample)
JP (1) JP2022517827A (enExample)
CN (1) CN113330312B (enExample)
CA (1) CA3125695A1 (enExample)
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JPWO2024185286A1 (enExample) * 2023-03-07 2024-09-12

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CN115541692A (zh) * 2022-10-20 2022-12-30 中国科学院兰州化学物理研究所 一种同时分析小扁豆萌发过程中多种脂类成分空间分布变化的质谱成像方法
CN117740919A (zh) * 2023-11-27 2024-03-22 中国科学院深圳先进技术研究院 一种肿瘤类器官空间成像表征方法

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JP2011519413A (ja) * 2008-03-14 2011-07-07 イースタン バージニア メディカル スクール 改良された前立腺癌診断学のための質量顕微鏡法
JP2017519816A (ja) * 2014-05-29 2017-07-20 スプリング バイオサイエンス コーポレーション 抗インドールアミン２，３−ジオキシゲナーゼ１抗体及びその診断的使用
WO2018017592A1 (en) * 2016-07-18 2018-01-25 Snapchat Inc. Real time painting of a video stream

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US8229194B2 (en) * 2006-11-16 2012-07-24 Visiopharm A/S Feature-based registration of sectional images
CN101975818B (zh) * 2010-04-29 2012-12-26 中国计量科学研究院 特征物质的检测系统及方法
FR2973112B1 (fr) * 2011-03-21 2018-05-25 Imabiotech Procede de detection et de quantification d'une molecule cible dans un echantillon
US20150262329A1 (en) * 2012-10-03 2015-09-17 KONINKLIJKE PHILIPS N.V. a corporation Combined sample examinations
WO2014078374A2 (en) * 2012-11-13 2014-05-22 Presage Biosciences, Inc. Methods for multiplexed drug evaluation
CA2899994C (en) * 2013-02-25 2022-08-30 Imabiotech Method to evaluate the tissue targeting of a molecule of interest
GB201413162D0 (en) * 2014-07-24 2014-09-10 Immusmol Sas Prediction of cancer treatment based on determination of enzymes or metabolites of the kynurenine pathway
FR3025317B1 (fr) * 2014-08-26 2022-09-23 Imabiotech Methode de caracterisation d'un echantillon par imagerie par spectrometrie de masse
CA3182538C (en) * 2015-06-11 2026-05-26 University Of Pittsburgh - Of The Commonwealth System Of Higher Educatio Systems and methods for finding regions of interest in hematoxylin and eosin (h&e) stained tissue images and quantifying intratumor cellular spatial heterogeneity in multiplexed/hyperplexed fluorescence tissue images
WO2017049403A1 (en) * 2015-09-22 2017-03-30 University Health Network System and method for optimized mass spectrometry analysis
CN107424156B (zh) * 2017-06-28 2019-12-06 北京航空航天大学 基于仿仓鸮眼视觉注意的无人机自主编队精准测量方法

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JP2011519413A (ja) * 2008-03-14 2011-07-07 イースタン バージニア メディカル スクール 改良された前立腺癌診断学のための質量顕微鏡法
JP2017519816A (ja) * 2014-05-29 2017-07-20 スプリング バイオサイエンス コーポレーション 抗インドールアミン２，３−ジオキシゲナーゼ１抗体及びその診断的使用
WO2018017592A1 (en) * 2016-07-18 2018-01-25 Snapchat Inc. Real time painting of a video stream

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MARIALAURA DILILLO ET AL.: "Mass Spectrometry Imaging, Laser Capture Microdissection, and LC-MS/MS of the Same Tissue Section", JOURNAL OF PROTEOME RESEARCH, vol. 16, no. 8, JPN6023050256, 5 July 2017 (2017-07-05), pages 2993 - 3001, ISSN: 0005412246 *
RIMA AIT-BELKACEM ET AL.: "Microenvironment Tumor Metabolic Interactions Highlighted by qMSI: Application to the Tryptophan-Kyn", SLAS DISCOVERY, vol. 22, no. 10, JPN7023004663, December 2017 (2017-12-01), pages 1182 - 1192, ISSN: 0005412245 *

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPWO2024185286A1 (enExample) * 2023-03-07 2024-09-12
WO2024185286A1 (ja) * 2023-03-07 2024-09-12 株式会社島津製作所 イメージング質量分析を用いた解析方法
JP7889719B2 (ja) 2023-03-07 2026-07-14 株式会社島津製作所 イメージング質量分析を用いた解析方法

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US20220137027A1 (en) 2022-05-05
WO2020152151A1 (en) 2020-07-30
CA3125695A1 (en) 2020-07-30
CN113330312A (zh) 2021-08-31
EP3914911A1 (en) 2021-12-01
CN113330312B (zh) 2025-03-21

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