JP2022513316A5 - - Google Patents
Info
- Publication number
- JP2022513316A5 JP2022513316A5 JP2021542071A JP2021542071A JP2022513316A5 JP 2022513316 A5 JP2022513316 A5 JP 2022513316A5 JP 2021542071 A JP2021542071 A JP 2021542071A JP 2021542071 A JP2021542071 A JP 2021542071A JP 2022513316 A5 JP2022513316 A5 JP 2022513316A5
- Authority
- JP
- Japan
- Prior art keywords
- roi
- cells
- ratio
- epithelial
- tumor
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2024036619A JP7802843B2 (ja) | 2018-10-01 | 2024-03-11 | Pd-1軸指向型治療薬に対する応答を予測するための方法およびシステム |
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862739828P | 2018-10-01 | 2018-10-01 | |
| US62/739,828 | 2018-10-01 | ||
| US201862742934P | 2018-10-09 | 2018-10-09 | |
| US62/742,934 | 2018-10-09 | ||
| PCT/US2019/053774 WO2020072348A1 (en) | 2018-10-01 | 2019-09-30 | Methods and systems for predicting response to pd-1 axis directed therapeutics |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024036619A Division JP7802843B2 (ja) | 2018-10-01 | 2024-03-11 | Pd-1軸指向型治療薬に対する応答を予測するための方法およびシステム |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2022513316A JP2022513316A (ja) | 2022-02-07 |
| JP2022513316A5 true JP2022513316A5 (https=) | 2022-10-11 |
| JP7510943B2 JP7510943B2 (ja) | 2024-07-04 |
Family
ID=68296689
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021542071A Active JP7510943B2 (ja) | 2018-10-01 | 2019-09-30 | Pd-1軸指向型治療薬に対する応答を予測するための方法およびシステム |
| JP2024036619A Active JP7802843B2 (ja) | 2018-10-01 | 2024-03-11 | Pd-1軸指向型治療薬に対する応答を予測するための方法およびシステム |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024036619A Active JP7802843B2 (ja) | 2018-10-01 | 2024-03-11 | Pd-1軸指向型治療薬に対する応答を予測するための方法およびシステム |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US12086985B2 (https=) |
| EP (1) | EP3861556A1 (https=) |
| JP (2) | JP7510943B2 (https=) |
| CN (1) | CN112789684B (https=) |
| WO (1) | WO2020072348A1 (https=) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3871183B1 (en) * | 2018-10-23 | 2024-10-09 | F. Hoffmann-La Roche AG | Distance-based tissue state determination |
| CN110866908B (zh) * | 2019-11-12 | 2021-03-26 | 腾讯科技(深圳)有限公司 | 图像处理方法、装置、服务器及存储介质 |
| EP4186026A1 (en) | 2020-07-21 | 2023-05-31 | F. Hoffmann-La Roche AG | Method of generating a metric to quantitatively represent an effect of a treatment |
| JP7629185B2 (ja) * | 2020-12-25 | 2025-02-13 | 株式会社カイ | 癌の再発可能性を判定する再発判定装置および再発判定方法 |
| US20240193772A1 (en) * | 2021-04-22 | 2024-06-13 | H. Lee Moffitt Cancer Center And Research Institute, Inc. | Quantifying the tumor-immune ecosystem in non-small cell lung cancer (nsclc) to identify clinical biomarkers of therapy response |
| AU2022288930A1 (en) * | 2021-06-09 | 2023-12-14 | The Johns Hopkins University | Method of predicting response to immunotherapy |
| CN113933505B (zh) * | 2021-12-15 | 2022-04-05 | 北京市肿瘤防治研究所 | 一组多维分析预测胃癌免疫治疗疗效的tiic指标及其应用 |
| JP2025513724A (ja) | 2022-03-31 | 2025-04-30 | ヴェンタナ メディカル システムズ, インク. | ミスマッチ修復が欠損した結腸直腸腫瘍におけるpd-1軸指向治療薬に対する応答を予測するための方法およびシステム |
| JP2025526652A (ja) * | 2022-08-08 | 2025-08-15 | ヴェンタナ メディカル システムズ, インク. | デジタル化された病理スライドの定量化のためのシステムおよび方法 |
| WO2024173431A1 (en) * | 2023-02-14 | 2024-08-22 | Genentech, Inc. | Nuclei-based digital pathology systems and methods |
| CN117218139B (zh) * | 2023-09-12 | 2024-05-24 | 珠海横琴圣澳云智科技有限公司 | 样本细胞密度的确定方法和装置 |
| JP7783452B1 (ja) * | 2025-03-28 | 2025-12-09 | 楽天グループ株式会社 | 情報処理装置、情報処理方法、およびプログラム |
Family Cites Families (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US1564604A (en) | 1925-06-12 | 1925-12-08 | Chas S Hodges | Water wheel |
| US5595707A (en) | 1990-03-02 | 1997-01-21 | Ventana Medical Systems, Inc. | Automated biological reaction apparatus |
| US20030211630A1 (en) | 1998-02-27 | 2003-11-13 | Ventana Medical Systems, Inc. | Automated molecular pathology apparatus having independent slide heaters |
| JP3847559B2 (ja) | 1998-02-27 | 2006-11-22 | ベンタナ・メデイカル・システムズ・インコーポレーテツド | 独立スライド加熱器を有する自動化分子病理学装置 |
| US6582962B1 (en) | 1998-02-27 | 2003-06-24 | Ventana Medical Systems, Inc. | Automated molecular pathology apparatus having independent slide heaters |
| US6372937B1 (en) | 1998-11-09 | 2002-04-16 | Mark Norman Bobrow | Enhanced catalyzed reporter deposition |
| US6670113B2 (en) | 2001-03-30 | 2003-12-30 | Nanoprobes | Enzymatic deposition and alteration of metals |
| DK1636586T3 (da) | 2003-06-24 | 2009-11-23 | Ventana Med Syst Inc | Enzymkatalyseret metaldeponering til foröget in situ-detektion af immunhistokemisker epitoper og nucleinsyresekvenser |
| US20050186642A1 (en) | 2004-02-24 | 2005-08-25 | Biocare Medical, Inc. | Immunoassay reagents and methods of use thereof |
| CA2842661C (en) | 2009-10-19 | 2016-02-23 | Ventana Medical Systems, Inc. | Imaging system and techniques |
| WO2011139978A1 (en) | 2010-05-04 | 2011-11-10 | Ventana Medical Systems, Inc. | Moving meniscus rinsing and mixing in cell staining |
| AU2011274369A1 (en) | 2010-07-02 | 2012-12-06 | Ventana Medical Systems, Inc. | Hapten conjugates for target detection |
| FR2988549B1 (fr) | 2012-03-22 | 2015-06-26 | Bodysens | Procede, terminal et casque de communication vocale sans fil avec auto-synchronisation |
| US8995740B2 (en) | 2013-04-17 | 2015-03-31 | General Electric Company | System and method for multiplexed biomarker quantitation using single cell segmentation on sequentially stained tissue |
| WO2015049233A1 (en) | 2013-10-01 | 2015-04-09 | Ventana Medical Systems, Inc. | Line-based image registration and cross-image annotation devices, systems and methods |
| CA2940439C (en) | 2014-02-24 | 2024-03-19 | Ventana Medical Systems, Inc. | Quinone methide analog signal amplification |
| US20160106836A1 (en) * | 2014-10-17 | 2016-04-21 | Definiens Ag | Immunotherapy Using a Logical AND Combination for Immune Response Activation |
| WO2016170008A1 (en) | 2015-04-20 | 2016-10-27 | Ventana Medical Systems, Inc. | Inkjet deposition of reagents for histological samples |
| WO2016179576A1 (en) | 2015-05-07 | 2016-11-10 | Bioxcel Corporation | Novel immunomodulatory therapeutic strategies targeting tumors in cancer |
| EP3371594A1 (en) * | 2015-11-06 | 2018-09-12 | Ventana Medical Systems, Inc. | Representative diagnostics |
| WO2017085307A1 (en) | 2015-11-22 | 2017-05-26 | Ventana Medical Systems, Inc. | Methods of identifying immune cells in pd-l1 positive tumor tissue |
| KR20180091024A (ko) * | 2015-12-02 | 2018-08-14 | 클리어라이트 다이어그노스틱스 엘엘씨 | 암의 검출 및 모니터링을 위해 종양 조직 시료를 준비하고 분석하는 방법 |
| US10718773B2 (en) * | 2016-04-01 | 2020-07-21 | Agilent Technologies, Inc. | Immunohistochemistry scoring methods and compositions |
| JP7128399B2 (ja) * | 2016-04-14 | 2022-08-31 | クリエイティブ マイクロテック インコーポレーテッド | 癌治療のための治療決定におけるpd-l1発現の使用方法 |
| EP3516397A1 (en) | 2016-09-23 | 2019-07-31 | Ventana Medical Systems, Inc. | Methods and systems for scoring extracellular matrix biomarkers in tumor samples |
| US20180112277A1 (en) * | 2016-10-26 | 2018-04-26 | Expression Pathology, Inc. | Signal directed dissection to inform cancer therapy strategy |
| CN110461342A (zh) | 2017-02-06 | 2019-11-15 | 诺华股份有限公司 | 预测对免疫疗法的反应的方法 |
| TW201837467A (zh) | 2017-03-01 | 2018-10-16 | 美商建南德克公司 | 用於癌症之診斷及治療方法 |
-
2019
- 2019-09-30 CN CN201980063834.8A patent/CN112789684B/zh active Active
- 2019-09-30 WO PCT/US2019/053774 patent/WO2020072348A1/en not_active Ceased
- 2019-09-30 JP JP2021542071A patent/JP7510943B2/ja active Active
- 2019-09-30 EP EP19790956.7A patent/EP3861556A1/en active Pending
-
2021
- 2021-03-30 US US17/218,087 patent/US12086985B2/en active Active
-
2024
- 2024-03-11 JP JP2024036619A patent/JP7802843B2/ja active Active
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2022513316A5 (https=) | ||
| JP6143743B2 (ja) | 細胞におけるバイオマーカーの発現のクラスターによる解析 | |
| JP2023512560A (ja) | 機械学習アルゴリズムを訓練し、患者のプライバシーを維持するための連合学習システム | |
| US8885912B2 (en) | Generate percentage of positive cells for biomarkers by normalizing and autothresholding the image intensity produced by immunohistochemistry technique | |
| CN112912923B (zh) | 基于距离的组织状态确定 | |
| Han et al. | Whole human-brain mapping of single cortical neurons for profiling morphological diversity and stereotypy | |
| US11922623B2 (en) | Cellular diagnostic and analysis methods | |
| KR20230012524A (ko) | 디지털 병리 영상에 대한 공간 특징 분석 | |
| Woloshuk et al. | In situ classification of cell types in human kidney tissue using 3D nuclear staining | |
| CN110956626B (zh) | 一种基于图像的预后评估方法及装置 | |
| JP2021508868A (ja) | 関心の細胞タイプに対する選択的染料セグメンテーション画像を生成するためのシステムおよび方法 | |
| CN116547727A (zh) | 基于注意力的多示例学习 | |
| US20180089495A1 (en) | Method for scoring pathology images using spatial analysis of tissues | |
| Lin et al. | Computer-assisted three-dimensional quantitation of programmed death-ligand 1 in non-small cell lung cancer using tissue clearing technology | |
| CN112136183A (zh) | 诊断辅助系统和诊断辅助装置 | |
| JP2024522094A (ja) | 空間分布解析に基づく腫瘍免疫表現型検査 | |
| Amaral et al. | Digital pathology and artificial intelligence in veterinary medicine | |
| Checcucci et al. | Deep learning-based localization algorithms on fluorescence human brain 3D reconstruction: a comparative study using stereology as a reference | |
| Jurtz et al. | Deep learning reveals 3D atherosclerotic plaque distribution and composition | |
| Freitas-Andrade et al. | Unbiased analysis of mouse brain endothelial networks from two-or three-dimensional fluorescence images | |
| CN119400432A (zh) | 一种多模态信息融合的肿瘤放疗预后的预测模型 | |
| CN120298369A (zh) | 用于预测肝癌超进展的多模态影像模型训练方法及装置 | |
| KR102598667B1 (ko) | 강직성 척추염 환자에 대한 생물학적제제의 반응성 예측 방법 및 분석 장치 | |
| US9865053B1 (en) | Method for scoring pathology images using spatial statistics of cells in tissues | |
| Ehrenreich et al. | Evaluation of digital image analysis as a supportive tool for the stratification of head and neck vascular anomalies |