JP2022512843A5 - - Google Patents

Info

Publication number
JP2022512843A5
JP2022512843A5 JP2021523243A JP2021523243A JP2022512843A5 JP 2022512843 A5 JP2022512843 A5 JP 2022512843A5 JP 2021523243 A JP2021523243 A JP 2021523243A JP 2021523243 A JP2021523243 A JP 2021523243A JP 2022512843 A5 JP2022512843 A5 JP 2022512843A5
Authority
JP
Japan
Prior art keywords
sphingosine kinase
aforementioned
present
amino acid
drug
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2021523243A
Other languages
English (en)
Japanese (ja)
Other versions
JP2022512843A (ja
Filing date
Publication date
Priority claimed from CN201811225720.2A external-priority patent/CN109355269B/zh
Application filed filed Critical
Publication of JP2022512843A publication Critical patent/JP2022512843A/ja
Publication of JP2022512843A5 publication Critical patent/JP2022512843A5/ja
Pending legal-status Critical Current

Links

JP2021523243A 2018-10-21 2019-09-20 スフィンゴシンキナーゼ1とその融合タンパク質およびその使用 Pending JP2022512843A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
CN201811225720.2A CN109355269B (zh) 2018-10-21 2018-10-21 鞘氨醇激酶1及其融合蛋白及其用途
CN201811225720.2 2018-10-21
PCT/CN2019/107091 WO2020082950A1 (zh) 2018-10-21 2019-09-20 鞘氨醇激酶1及其融合蛋白及其用途

Publications (2)

Publication Number Publication Date
JP2022512843A JP2022512843A (ja) 2022-02-07
JP2022512843A5 true JP2022512843A5 (https=) 2023-04-05

Family

ID=65345959

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2021523243A Pending JP2022512843A (ja) 2018-10-21 2019-09-20 スフィンゴシンキナーゼ1とその融合タンパク質およびその使用

Country Status (4)

Country Link
US (1) US20210388326A1 (https=)
JP (1) JP2022512843A (https=)
CN (1) CN109355269B (https=)
WO (1) WO2020082950A1 (https=)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109355269B (zh) * 2018-10-21 2020-03-24 北京双因生物科技有限公司 鞘氨醇激酶1及其融合蛋白及其用途
CN111303298B (zh) * 2020-02-19 2023-03-21 李瑛� 含有磷酸酶的融合蛋白及其产品和应用
CN112143705B (zh) * 2020-09-23 2022-09-06 北京华奥玄德生物医药科技有限公司 一种双基因修饰的干细胞及其用途
CN114762724A (zh) * 2020-12-31 2022-07-19 吴伯骥 HrpWEch蛋白在识别激活多类受体和/或膜蛋白及其信号通路的制药中的应用
CN114762723A (zh) * 2020-12-31 2022-07-19 吴伯骥 HrpZpst蛋白在识别激活多类受体和/或膜蛋白及其信号通路的制药中的应用
CN112675293A (zh) * 2020-12-31 2021-04-20 吴伯骥 HrpNEcb蛋白在识别激活多类受体和/或膜蛋白及其信号通路的制药中的应用

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2003512072A (ja) * 1999-10-28 2003-04-02 ワーナー−ランバート・カンパニー ヒトスフィンゴシンキナーゼ遺伝子
US6610534B2 (en) * 2000-10-05 2003-08-26 Novartis Ag Induction of blood vessel formation through administration of polynucleotides encoding sphingosine kinases
AU2003292636A1 (en) * 2002-12-27 2004-07-29 The New Industry Research Organization Cell growth inhibitor using sphingosine kinase 2, method of constructing fused protein having its nuclear localization signal, method of screening drug candidate, and screening kit
WO2014135984A2 (en) * 2013-03-07 2014-09-12 Recopharma Ab Glycosylated mucin-immunoglobulin fusion protein coated device
JP6324137B2 (ja) * 2014-03-24 2018-05-16 ジヤトコ株式会社 シール機構付き車両用無段変速機
CN106279430B (zh) * 2015-06-30 2017-11-28 安源医药科技(上海)有限公司 Exendin‑4类似物融合蛋白及其制备方法和用途
CN106432511A (zh) * 2016-09-29 2017-02-22 上海凯茂生物医药有限公司 GLP‑1类似物‑Fc融合蛋白及其制备方法和用途
CN107875398B (zh) * 2017-09-27 2021-03-23 浙江大学 一种抗体偶联药物的制备方法、抗体偶联药物及应用
CN109355269B (zh) * 2018-10-21 2020-03-24 北京双因生物科技有限公司 鞘氨醇激酶1及其融合蛋白及其用途

Similar Documents

Publication Publication Date Title
JP2022512843A5 (https=)
Halberg et al. Efficacy and safety of oral basal insulin versus subcutaneous insulin glargine in type 2 diabetes: a randomised, double-blind, phase 2 trial
Aronson Meyler's side effects of drugs 15E: The international encyclopedia of adverse drug reactions and interactions
Eliaschewitz et al. Therapy in type 2 diabetes: insulin glargine vs. NPH insulin both in combination with glimepiride
CN112313755B (zh) 为基础胰岛素滴定提供剂量推荐的系统
Rodbard et al. Reduced risk of hypoglycemia with insulin degludec versus insulin glargine in patients with type 2 diabetes requiring high doses of basal insulin: a meta-analysis of 5 randomized begin trials
JP2015143253A5 (https=)
CN105142661B (zh) 通过长效胰岛素制剂治疗糖尿病
Tak et al. Effect of oral ingestion of low-molecular collagen peptides derived from skate (Raja Kenojei) skin on body fat in overweight adults: a randomized, double-blind, placebo-controlled trial
Hollander et al. Effects of taspoglutide on glycemic control and body weight in obese patients with type 2 diabetes (T‐emerge 7 study)
AU2016226906B2 (en) Composition for improving or preventing nonalcoholic fatty liver
Helms et al. Insulin glulisine: an evaluation of its pharmacodynamic properties and clinical application
JP2018027983A (ja) 運動機能性向上剤
RU2011137413A (ru) Применение кардиотрофина-1 для лечения метаболических заболеваний
WO2020103889A1 (zh) 抑郁症治疗方法和药物
JP6288757B2 (ja) 運動機能性向上剤
CN108096568A (zh) A型肉毒毒素在抗抑郁症中的应用
EA200600917A1 (ru) Композиция, обладающая гепатопротекторной активностью и нормализующая обменные процессы
US20160158309A1 (en) Exercise function enhancer
CN104906501A (zh) 治疗银屑病的中药组分组合物
JP6565085B2 (ja) 低血糖症状緩和剤
CN105982893B (zh) 一种抗抑郁的组合物及其应用
Puranik Ayurveda and Metabolic Diseases: The Whole is Greater than the
CN106983742A (zh) 一种2型糖尿病的多药联用康复冲剂及其应用
Karpenko et al. Comparative study of the antigyperglicemic action of antidiabetic phytomedication on the model of diabetes mellitus type 2