JP2022512538A - Ｅｂｖ関連がんの処置のための抗ｌｍｐ２ ｔｃｒ－ｔ細胞療法 - Google Patents

Ｅｂｖ関連がんの処置のための抗ｌｍｐ２ ｔｃｒ－ｔ細胞療法 Download PDF

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JP2022512538A
JP2022512538A JP2021510452A JP2021510452A JP2022512538A JP 2022512538 A JP2022512538 A JP 2022512538A JP 2021510452 A JP2021510452 A JP 2021510452A JP 2021510452 A JP2021510452 A JP 2021510452A JP 2022512538 A JP2022512538 A JP 2022512538A
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cancer
tcr
cells
seq
lmp2
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JPWO2020112815A5 (https=
JP2022512538A5 (https=
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シャオ－ファン ワン，
ピーター アレクサンダー，
チー－ジン リー，
グオピン ワン，
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Duke University
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Duke University
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    • C—CHEMISTRY; METALLURGY
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    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
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    • C12N5/0602—Vertebrate cells
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    • A61K35/17—Lymphocytes; B-cells; T-cells; Natural killer cells; Interferon-activated or cytokine-activated lymphocytes
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JP2021510452A 2018-11-27 2019-11-26 Ｅｂｖ関連がんの処置のための抗ｌｍｐ２ ｔｃｒ－ｔ細胞療法 Pending JP2022512538A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201862771653P 2018-11-27 2018-11-27
US62/771,653 2018-11-27
PCT/US2019/063310 WO2020112815A1 (en) 2018-11-27 2019-11-26 Anti-lmp2 tcr-t cell therapy for the treatment of ebv-associated cancers

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JP2022512538A true JP2022512538A (ja) 2022-02-07
JPWO2020112815A5 JPWO2020112815A5 (https=) 2022-12-05
JP2022512538A5 JP2022512538A5 (https=) 2022-12-05

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US (1) US12139523B2 (https=)
JP (1) JP2022512538A (https=)
KR (1) KR20210098940A (https=)
CN (1) CN113166224A (https=)
SG (1) SG11202101671PA (https=)
TW (1) TW202039540A (https=)
WO (1) WO2020112815A1 (https=)

Families Citing this family (6)

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Publication number Priority date Publication date Assignee Title
CN113621070A (zh) 2020-05-06 2021-11-09 华夏英泰（北京）生物技术有限公司 一种t细胞抗原受体、其多聚体复合物及其制备方法和应用
WO2021243695A1 (en) * 2020-06-05 2021-12-09 Guangdong Tcrcure Biopharma Technology Co., Ltd. Tcr-t cell therapy targeting epstein-barr virus
CN112940108B (zh) * 2021-03-19 2022-10-14 河南省肿瘤医院 识别ebv抗原的t细胞受体以及该t细胞受体的应用
WO2023092452A1 (zh) * 2021-11-26 2023-06-01 上海吉倍生物技术有限公司 识别ebv lmp2抗原的t细胞受体及其应用
WO2025059162A1 (en) 2023-09-11 2025-03-20 Dana-Farber Cancer Institute, Inc. Car-engager containing il-2 variants to enhance the functionality of car t cells
CN119390814B (zh) * 2023-10-26 2025-06-27 上海市第一人民医院 一种t细胞受体及其制备方法和用途

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JP2016528244A (ja) * 2013-08-12 2016-09-15 イムノコア リミテッド Ｔ細胞レセプター

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US8834889B2 (en) * 2011-08-29 2014-09-16 National Tsing Hua University Antigen presenting composition and use thereof
WO2016095783A1 (zh) 2014-12-17 2016-06-23 中国科学院广州生物医药与健康研究院 识别eb病毒短肽的t细胞受体
EP3331913A1 (en) 2015-08-07 2018-06-13 Novartis AG Treatment of cancer using chimeric cd3 receptor proteins
GB201520191D0 (en) * 2015-11-16 2015-12-30 Cancer Rec Tech Ltd T-cell receptor and uses thereof
GB201522592D0 (en) * 2015-12-22 2016-02-03 Immunocore Ltd T cell receptors
CN106632659A (zh) * 2016-08-05 2017-05-10 武汉赛云博生物科技有限公司 一种eb病毒特异性tcr及其重组慢病毒载体与应用
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CN110582509A (zh) * 2017-01-31 2019-12-17 诺华股份有限公司 使用具有多特异性的嵌合t细胞受体蛋白治疗癌症

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WO2020112815A1 (en) 2020-06-04
CN113166224A (zh) 2021-07-23
SG11202101671PA (en) 2021-03-30
US12139523B2 (en) 2024-11-12
TW202039540A (zh) 2020-11-01
US20220056101A1 (en) 2022-02-24
KR20210098940A (ko) 2021-08-11

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