JP2022141959A5 - - Google Patents
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- Publication number
- JP2022141959A5 JP2022141959A5 JP2022120801A JP2022120801A JP2022141959A5 JP 2022141959 A5 JP2022141959 A5 JP 2022141959A5 JP 2022120801 A JP2022120801 A JP 2022120801A JP 2022120801 A JP2022120801 A JP 2022120801A JP 2022141959 A5 JP2022141959 A5 JP 2022141959A5
- Authority
- JP
- Japan
- Prior art keywords
- antibody
- seq
- amino acid
- acid sequence
- fcγriia
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 125000003275 alpha amino acid group Chemical group 0.000 claims 8
- 239000008194 pharmaceutical composition Substances 0.000 claims 6
- 108010021468 Fc gamma receptor IIA Proteins 0.000 claims 5
- 102100029204 Low affinity immunoglobulin gamma Fc region receptor II-a Human genes 0.000 claims 5
- 208000023275 Autoimmune disease Diseases 0.000 claims 4
- 208000026935 allergic disease Diseases 0.000 claims 4
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 4
- 208000027866 inflammatory disease Diseases 0.000 claims 4
- 108010021472 Fc gamma receptor IIB Proteins 0.000 claims 3
- 102100029205 Low affinity immunoglobulin gamma Fc region receptor II-b Human genes 0.000 claims 3
- 102100029193 Low affinity immunoglobulin gamma Fc region receptor III-A Human genes 0.000 claims 3
- 101710099301 Low affinity immunoglobulin gamma Fc region receptor III-A Proteins 0.000 claims 3
- 201000010099 disease Diseases 0.000 claims 3
- 206010012438 Dermatitis atopic Diseases 0.000 claims 2
- 208000004262 Food Hypersensitivity Diseases 0.000 claims 2
- 206010016946 Food allergy Diseases 0.000 claims 2
- 101000969553 Homo sapiens Cell surface glycoprotein CD200 receptor 1 Proteins 0.000 claims 2
- 208000006673 asthma Diseases 0.000 claims 2
- 201000008937 atopic dermatitis Diseases 0.000 claims 2
- 235000020932 food allergy Nutrition 0.000 claims 2
- 201000006417 multiple sclerosis Diseases 0.000 claims 2
- 201000000596 systemic lupus erythematosus Diseases 0.000 claims 2
- FWMNVWWHGCHHJJ-SKKKGAJSSA-N 4-amino-1-[(2r)-6-amino-2-[[(2r)-2-[[(2r)-2-[[(2r)-2-amino-3-phenylpropanoyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]hexanoyl]piperidine-4-carboxylic acid Chemical group C([C@H](C(=O)N[C@H](CC(C)C)C(=O)N[C@H](CCCCN)C(=O)N1CCC(N)(CC1)C(O)=O)NC(=O)[C@H](N)CC=1C=CC=CC=1)C1=CC=CC=C1 FWMNVWWHGCHHJJ-SKKKGAJSSA-N 0.000 claims 1
- ODHCTXKNWHHXJC-VKHMYHEASA-N 5-oxo-L-proline Chemical compound OC(=O)[C@@H]1CCC(=O)N1 ODHCTXKNWHHXJC-VKHMYHEASA-N 0.000 claims 1
- 102100021396 Cell surface glycoprotein CD200 receptor 1 Human genes 0.000 claims 1
- ODHCTXKNWHHXJC-GSVOUGTGSA-N Pyroglutamic acid Natural products OC(=O)[C@H]1CCC(=O)N1 ODHCTXKNWHHXJC-GSVOUGTGSA-N 0.000 claims 1
- ODHCTXKNWHHXJC-UHFFFAOYSA-N acide pyroglutamique Natural products OC(=O)C1CCC(=O)N1 ODHCTXKNWHHXJC-UHFFFAOYSA-N 0.000 claims 1
- 239000000556 agonist Substances 0.000 claims 1
- 239000003085 diluting agent Substances 0.000 claims 1
- 239000003814 drug Substances 0.000 claims 1
- 239000003937 drug carrier Substances 0.000 claims 1
- 208000024711 extrinsic asthma Diseases 0.000 claims 1
- ZDXPYRJPNDTMRX-UHFFFAOYSA-N glutamine Natural products OC(=O)C(N)CCC(N)=O ZDXPYRJPNDTMRX-UHFFFAOYSA-N 0.000 claims 1
- 102000057542 human CD200R1 Human genes 0.000 claims 1
- 208000002551 irritable bowel syndrome Diseases 0.000 claims 1
- 239000002085 irritant Substances 0.000 claims 1
- 231100000021 irritant Toxicity 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
- 239000000546 pharmaceutical excipient Substances 0.000 claims 1
- 238000002198 surface plasmon resonance spectroscopy Methods 0.000 claims 1
- 238000002560 therapeutic procedure Methods 0.000 claims 1
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2024078485A JP2024105529A (ja) | 2018-09-14 | 2024-05-14 | Ｃｄ２００ｒアゴニスト抗体およびそれらの使用 |
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862731204P | 2018-09-14 | 2018-09-14 | |
| US62/731,204 | 2018-09-14 | ||
| JP2021538177A JP7185051B2 (ja) | 2018-09-14 | 2019-09-11 | Ｃｄ２００ｒアゴニスト抗体およびそれらの使用 |
| PCT/US2019/050511 WO2020055943A1 (en) | 2018-09-14 | 2019-09-11 | Cd200r agonist antibodies and uses thereof |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021538177A Division JP7185051B2 (ja) | 2018-09-14 | 2019-09-11 | Ｃｄ２００ｒアゴニスト抗体およびそれらの使用 |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024078485A Division JP2024105529A (ja) | 2018-09-14 | 2024-05-14 | Ｃｄ２００ｒアゴニスト抗体およびそれらの使用 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2022141959A JP2022141959A (ja) | 2022-09-29 |
| JP2022141959A5 true JP2022141959A5 (https=) | 2023-05-19 |
| JP7490025B2 JP7490025B2 (ja) | 2024-05-24 |
Family
ID=68051977
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021538177A Active JP7185051B2 (ja) | 2018-09-14 | 2019-09-11 | Ｃｄ２００ｒアゴニスト抗体およびそれらの使用 |
| JP2022120801A Active JP7490025B2 (ja) | 2018-09-14 | 2022-07-28 | Ｃｄ２００ｒアゴニスト抗体およびそれらの使用 |
| JP2024078485A Pending JP2024105529A (ja) | 2018-09-14 | 2024-05-14 | Ｃｄ２００ｒアゴニスト抗体およびそれらの使用 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021538177A Active JP7185051B2 (ja) | 2018-09-14 | 2019-09-11 | Ｃｄ２００ｒアゴニスト抗体およびそれらの使用 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024078485A Pending JP2024105529A (ja) | 2018-09-14 | 2024-05-14 | Ｃｄ２００ｒアゴニスト抗体およびそれらの使用 |
Country Status (27)
| Country | Link |
|---|---|
| US (2) | US11319370B2 (https=) |
| EP (1) | EP3849667A1 (https=) |
| JP (3) | JP7185051B2 (https=) |
| KR (1) | KR102705378B1 (https=) |
| CN (2) | CN112739422B (https=) |
| AR (1) | AR116668A1 (https=) |
| AU (1) | AU2019339334B2 (https=) |
| BR (1) | BR112021003254A2 (https=) |
| CA (1) | CA3112763C (https=) |
| CL (1) | CL2021000606A1 (https=) |
| CO (1) | CO2021003093A2 (https=) |
| CR (1) | CR20210134A (https=) |
| DO (1) | DOP2021000040A (https=) |
| EA (1) | EA202190530A1 (https=) |
| EC (1) | ECSP21017619A (https=) |
| IL (1) | IL281442B2 (https=) |
| JO (1) | JOP20210048B1 (https=) |
| MA (1) | MA53604A (https=) |
| MX (1) | MX2021003026A (https=) |
| MY (1) | MY196156A (https=) |
| NZ (1) | NZ773626A (https=) |
| PE (1) | PE20211742A1 (https=) |
| PH (1) | PH12021550530A1 (https=) |
| SG (1) | SG11202101697YA (https=) |
| TW (1) | TWI749367B (https=) |
| WO (1) | WO2020055943A1 (https=) |
| ZA (2) | ZA202101246B (https=) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP4045641A1 (en) | 2019-10-15 | 2022-08-24 | Eli Lilly and Company | Recombinantly engineered, lipase/esterase-deficient mammalian cell lines |
| CN116323665A (zh) | 2020-05-29 | 2023-06-23 | 23和我公司 | 抗cd200r1抗体及其使用方法 |
| PE20251170A1 (es) * | 2022-04-06 | 2025-04-23 | Mirobio Ltd | Anticuerpos cd200r disenados por ingenieria y usos de estos |
| CN115458048B (zh) * | 2022-09-16 | 2023-05-26 | 杭州美赛生物医药科技有限公司 | 基于序列编解码的抗体人源化方法 |
| AU2024282979A1 (en) | 2023-06-02 | 2026-01-22 | Aimed Bio Inc. | Anti-cd200r1 antibody and use thereof |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7368535B2 (en) * | 2001-05-24 | 2008-05-06 | Trillium Therapeutics Inc. | CD200 receptors |
| DK1482973T3 (da) * | 2002-03-15 | 2009-12-07 | Schering Corp | Fremgangsmåde til modulering af CD200-receptorer |
| HUE028179T2 (en) * | 2006-01-12 | 2016-12-28 | Alexion Pharma Inc | Antibodies to OX-2 / CD200 and their use |
| KR20090094846A (ko) | 2006-12-22 | 2009-09-08 | 쉐링 코포레이션 | Ｃｄ200ｒ에 대한 항체 |
| CA2786692A1 (en) * | 2010-01-11 | 2011-07-14 | Alexion Pharmaceuticals, Inc. | Biomarkers of immunomodulatory effects in humans treated with anti-cd200 antibodies |
| WO2011100538A1 (en) * | 2010-02-11 | 2011-08-18 | Alexion Pharmaceuticals, Inc. | Therapeutic methods using an ti-cd200 antibodies |
| WO2015057906A1 (en) | 2013-10-16 | 2015-04-23 | Janssen Biotech, Inc. | Cd200 receptor 1 agonists |
-
2019
- 2019-09-10 AR ARP190102571A patent/AR116668A1/es unknown
- 2019-09-10 TW TW108132514A patent/TWI749367B/zh active
- 2019-09-11 WO PCT/US2019/050511 patent/WO2020055943A1/en not_active Ceased
- 2019-09-11 NZ NZ773626A patent/NZ773626A/en not_active IP Right Cessation
- 2019-09-11 PE PE2021000243A patent/PE20211742A1/es unknown
- 2019-09-11 EA EA202190530A patent/EA202190530A1/ru unknown
- 2019-09-11 CA CA3112763A patent/CA3112763C/en active Active
- 2019-09-11 MX MX2021003026A patent/MX2021003026A/es unknown
- 2019-09-11 CR CR20210134A patent/CR20210134A/es unknown
- 2019-09-11 JP JP2021538177A patent/JP7185051B2/ja active Active
- 2019-09-11 AU AU2019339334A patent/AU2019339334B2/en active Active
- 2019-09-11 CN CN201980060272.1A patent/CN112739422B/zh active Active
- 2019-09-11 BR BR112021003254-1A patent/BR112021003254A2/pt unknown
- 2019-09-11 CN CN202410652453.6A patent/CN118530360A/zh not_active Withdrawn
- 2019-09-11 MY MYPI2021001321A patent/MY196156A/en unknown
- 2019-09-11 KR KR1020217007520A patent/KR102705378B1/ko active Active
- 2019-09-11 IL IL281442A patent/IL281442B2/en unknown
- 2019-09-11 US US16/567,256 patent/US11319370B2/en active Active
- 2019-09-11 EP EP19773670.5A patent/EP3849667A1/en active Pending
- 2019-09-11 MA MA053604A patent/MA53604A/fr unknown
- 2019-09-11 SG SG11202101697YA patent/SG11202101697YA/en unknown
-
2021
- 2021-02-24 ZA ZA2021/01246A patent/ZA202101246B/en unknown
- 2021-03-02 DO DO2021000040A patent/DOP2021000040A/es unknown
- 2021-03-09 CO CONC2021/0003093A patent/CO2021003093A2/es unknown
- 2021-03-11 CL CL2021000606A patent/CL2021000606A1/es unknown
- 2021-03-11 PH PH12021550530A patent/PH12021550530A1/en unknown
- 2021-03-11 JO JOJO/P/2021/0048A patent/JOP20210048B1/ar active
- 2021-03-12 EC ECSENADI202117619A patent/ECSP21017619A/es unknown
-
2022
- 2022-04-21 US US17/726,262 patent/US20220251198A1/en not_active Abandoned
- 2022-05-06 ZA ZA2022/04978A patent/ZA202204978B/en unknown
- 2022-07-28 JP JP2022120801A patent/JP7490025B2/ja active Active
-
2024
- 2024-05-14 JP JP2024078485A patent/JP2024105529A/ja active Pending
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