JP2022098479A - センサ装置および使用方法 - Google Patents
センサ装置および使用方法 Download PDFInfo
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- JP2022098479A JP2022098479A JP2021205714A JP2021205714A JP2022098479A JP 2022098479 A JP2022098479 A JP 2022098479A JP 2021205714 A JP2021205714 A JP 2021205714A JP 2021205714 A JP2021205714 A JP 2021205714A JP 2022098479 A JP2022098479 A JP 2022098479A
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Abstract
Description
Claims (15)
- IVD分析装置(100)内でセンサ装置(1、1’)を動作させるための方法であって、前記センサ装置が、流体を繰り返し受け取るための少なくとも2つの流体導管(2、2’、3)を備え、各流体導管が、それぞれの前記流体導管(2、2’、3)内の前記流体と接触するように配置された少なくとも1つの検知要素(11A、11B、12A、12B、13、14、15)を備え、
前記少なくとも2つの流体導管(2、2’、3)が、異なる検知要素(11A、12A、13、14、15)をそれぞれ備える少なくとも2つの一次流体導管(2、2’)を備え、前記検知要素(11A、12A、13、14、15)が、劣化のしやすさまたは測定原理または動作条件または干渉の程度に従ってそれぞれの前記一次流体導管(2、2’)内で分けられ、
前記方法が、前記少なくとも2つの一次流体導管(2、2’)が流体を受け取ることを可能にすることと、前記少なくとも2つの一次流体導管(2、2’)に流体を繰り返し供給することとを含み、または
前記少なくとも2つの流体導管が、少なくとも1つの一次流体導管(2)および少なくとも1つの二次流体導管(3)を備え、前記二次流体導管(3)が、前記少なくとも1つの一次流体導管(2)と少なくとも部分的に同じ検知要素(11A、12A、13、14、15)を備え、
前記方法が、
前記少なくとも1つの一次流体導管(2)が流体を受け取ることが可能にされる一次動作モードにおいて前記センサ装置(1’)を動作させることと、
前記少なくとも1つの一次流体導管(2)に流体を繰り返し供給することと、
所定のトリガイベントに応答して、前記少なくとも1つの二次試料導管(3)が流体を受け取ることが可能にされる拡張動作モードに切り替え、前記少なくとも1つの一次流体導管(2)および/または前記少なくとも1つの二次流体導管(3)に流体を繰り返し供給することと、を含む、方法。 - 各流体導管(2、2’、3)内の動作温度を別々に調整することをさらに含む、請求項1に記載の方法。
- 前記所定のトリガイベントが、前記少なくとも1つの一次流体導管(2)内の少なくとも1つの検知要素(11A、12A、13、14、15)の性能が仕様外であることを検出することを含む、請求項1または2に記載の方法。
- 前記拡張動作モードが調整ステップを含み、前記調整ステップが、
前記少なくとも1つの二次流体導管(3)を調整するために前記少なくとも1つの二次流体導管(3)に調整流体を供給することを含む、請求項1から3のいずれかに記載の方法。 - 前記調整ステップを実行しながら、前記少なくとも1つの二次流体導管(3)の動作温度を前記少なくとも1つの一次流体導管(2)の動作温度よりも高くなるように調整することを含む、請求項4に記載の方法。
- IVD分析装置(100)用のセンサ装置(1、1’)であって、
流体を繰り返し受け取るための少なくとも2つの流体導管(2、2’、3)であって、各流体導管が、それぞれの前記流体導管(2、2’、3)内の流体と接触するように配置された少なくとも1つの検知要素(11A、11B、12A、12B、13、14、15)を備える、少なくとも2つの流体導管を備え、
前記少なくとも2つの流体導管(2、2’、3)が、異なる検知要素(11A、12A、13、14、15)をそれぞれ備える少なくとも2つの一次流体導管(2、2’)を備え、前記検知要素(11A、12A、13、14、15)が、劣化のしやすさまたは測定原理または動作条件または干渉の程度に従ってそれぞれの前記一次流体導管(2、2’)内で分離され、または
前記少なくとも2つの流体導管(2、2’、3)が、少なくとも1つの一次流体導管(2)および少なくとも1つの二次流体導管(3)を備え、前記二次流体導管(3)が、前記少なくとも1つの一次流体導管(2)と少なくとも部分的に同じ検知要素(11A、12A、13、14、15)を備える、センサ装置。 - 前記検知要素(11A、11B、12A、12B、13、14、15)が、電気化学センサまたは導電率センサまたは光学センサのいずれかを含む、請求項6に記載のセンサ装置(1、1’)。
- 電気化学センサを含む前記検知要素(11A、11B、12A、12B、13、14)が、イオン選択性電極センサ(11A、11B、14)または酵素結合センサ(12A、12B)または血液ガスセンサ(13)のいずれかを含む、請求項7に記載のセンサ装置(1、1’)。
- 前記少なくとも1つの一次流体導管(2)および前記少なくとも1つの二次流体導管(3)において同じである前記検知要素(11A、11B、12A、12B、13、14、15)が、前記一次流体導管内の他の前記検知要素よりも劣化しやすい検知要素である、請求項6から8のいずれかに記載のセンサ装置(1、1’)。
- 劣化しやすい前記検知要素(11A、11B、12A、12B、13、14、15)が、酵素結合センサ(12A、12B)および/またはイオン選択性電極センサ(11A、11B、14)のいずれかを含む、請求項9に記載のセンサ装置(1、1’)。
- 参照溶液を受け取るための参照導管(4)を備え、前記参照導管(4)が少なくとも1つの参照検知要素(11B、12B、15)を備え、前記少なくとも1つの参照検知要素(11B、12B、15)が前記参照導管(4)内の前記参照溶液と接触するように配置され、前記少なくとも1つの参照検知要素(11B、12B、15)が前記少なくとも2つの流体導管(2、2’、3)内の前記検知要素(11A、12A、13、14、15)の少なくとも一部とさらに動作可能に接続している、請求項6から10のいずれかに記載のセンサ装置(1、1’)。
- 各流体導管(2、2’、3)内の動作温度を別々に調整するための複数の熱伝導性素子(20、21)を備える、請求項6から11のいずれかに記載のセンサ装置(1、1’)。
- 前記少なくとも2つの流体導管(2、2’、3)用の少なくとも1つの共通流体入口(5)を備え、前記少なくとも2つの流体導管(2、2’、3)のいずれかに流体を別々にまたは同時に導くための切り替え可能バルブ(9)を備える、請求項6から12のいずれかに記載のセンサ装置(1、1’)。
- 前記少なくとも2つの流体導管(2、2’、3)のそれぞれおよび参照導管(4)と流体接続する少なくとも1つの共通流体出口(7)を備える、請求項6から13のいずれかに記載のセンサ装置(1、1’)。
- IVD分析装置(100)であって、
請求項6に記載のセンサ装置(1、1’)を受け入れるためのレセプタクル(30)であって、センサ装置(1、1’)が前記IVD分析装置(100)と動作可能に接続されている、レセプタクル(30)と、
コントローラ(40)であって、前記コントローラ(40)が、前記IVD分析装置(100)を制御し、その結果、
前記センサ装置(1、1’)の前記少なくとも2つの一次流体導管(2、2’)が流体を受け取ることを可能にし、
前記センサ装置(1)の前記少なくとも2つの一次流体導管(2、2’)に流体を繰り返し供給し、または
前記センサ装置(1’)を一次動作モードで動作させ、この場合に、前記コントローラ(40)が、前記少なくとも1つの一次流体導管(2)が流体を受け取ることを可能にするように前記IVD分析装置(100)を制御し、前記少なくとも1つの一次流体導管(2)に流体を供給するように前記IVD分析装置(100)を制御し、
所定のトリガイベントに応答して、拡張動作モードに切り替え、この場合に、前記コントローラ(40)が、前記少なくとも1つの二次試料導管(3)が流体を受け取ることを可能にするように前記IVD分析装置(100)を制御し、前記少なくとも1つの一次流体導管(2)および/または前記少なくとも1つの二次流体導管(3)に流体を供給するように前記IVD分析装置(100)を制御する、ように構成された、コントローラと、を備える、IVD分析装置。
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