JP2021534799A5 - - Google Patents

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Publication number
JP2021534799A5
JP2021534799A5 JP2021511621A JP2021511621A JP2021534799A5 JP 2021534799 A5 JP2021534799 A5 JP 2021534799A5 JP 2021511621 A JP2021511621 A JP 2021511621A JP 2021511621 A JP2021511621 A JP 2021511621A JP 2021534799 A5 JP2021534799 A5 JP 2021534799A5
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JP
Japan
Prior art keywords
sequence
kit
antisense oligomer
target
seq
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2021511621A
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English (en)
Japanese (ja)
Other versions
JP7677628B2 (ja
JP2021534799A (ja
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Priority claimed from PCT/US2019/048400 external-priority patent/WO2020046985A1/en
Publication of JP2021534799A publication Critical patent/JP2021534799A/ja
Publication of JP2021534799A5 publication Critical patent/JP2021534799A5/ja
Priority to JP2025071212A priority Critical patent/JP2025121926A/ja
Application granted granted Critical
Publication of JP7677628B2 publication Critical patent/JP7677628B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

JP2021511621A 2018-08-27 2019-08-27 肥満細胞のアポトーシスを誘導するためにスプライススイッチングオリゴヌクレオチドを用いてKitを標的とする方法 Active JP7677628B2 (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2025071212A JP2025121926A (ja) 2018-08-27 2025-04-23 肥満細胞のアポトーシスを誘導するためにスプライススイッチングオリゴヌクレオチドを用いてKitを標的とする方法

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201862723326P 2018-08-27 2018-08-27
US62/723,326 2018-08-27
PCT/US2019/048400 WO2020046985A1 (en) 2018-08-27 2019-08-27 Targeting kit with splice switching oligonucleotides to induce apoptosis of mast cells

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2025071212A Division JP2025121926A (ja) 2018-08-27 2025-04-23 肥満細胞のアポトーシスを誘導するためにスプライススイッチングオリゴヌクレオチドを用いてKitを標的とする方法

Publications (3)

Publication Number Publication Date
JP2021534799A JP2021534799A (ja) 2021-12-16
JP2021534799A5 true JP2021534799A5 (https=) 2022-09-05
JP7677628B2 JP7677628B2 (ja) 2025-05-15

Family

ID=69644689

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2021511621A Active JP7677628B2 (ja) 2018-08-27 2019-08-27 肥満細胞のアポトーシスを誘導するためにスプライススイッチングオリゴヌクレオチドを用いてKitを標的とする方法
JP2025071212A Pending JP2025121926A (ja) 2018-08-27 2025-04-23 肥満細胞のアポトーシスを誘導するためにスプライススイッチングオリゴヌクレオチドを用いてKitを標的とする方法

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2025071212A Pending JP2025121926A (ja) 2018-08-27 2025-04-23 肥満細胞のアポトーシスを誘導するためにスプライススイッチングオリゴヌクレオチドを用いてKitを標的とする方法

Country Status (6)

Country Link
US (1) US20210363531A1 (https=)
EP (1) EP3844278A4 (https=)
JP (2) JP7677628B2 (https=)
CN (1) CN112771162B (https=)
CA (1) CA3110353A1 (https=)
WO (1) WO2020046985A1 (https=)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2017136435A1 (en) 2016-02-01 2017-08-10 The Usa, As Represented By The Secretary, Department Of Health And Human Services Office Of Technology Transfer National Institute Of Health Compounds for modulating fc-epsilon-ri-beta expression and uses thereof
WO2025231071A1 (en) * 2024-05-01 2025-11-06 Beam Therapeutics Inc. Compositions and methods for cell conditioning
CN121177520B (zh) * 2025-11-24 2026-03-27 首都医科大学附属北京口腔医院 含有c-Kit的生物制品及其在调控牙源性器官组织发育中的应用

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK0423980T3 (da) * 1989-10-16 2000-10-09 Amgen Inc Stamcellefaktor
CA2107915A1 (en) * 1991-05-09 1992-11-12 Temple University Of The Commonwealth System Of Higher Education Antisense oligonucleotides to c-kit proto-oncogene and uses thereof
US5989849A (en) * 1991-05-09 1999-11-23 Temple University Of The Commonwealth System Of Higher Education Antisense of oligonucleotides to c-kit proto-oncogene and in vitro methods
US5641625A (en) * 1992-05-22 1997-06-24 Isis Pharmaceuticals, Inc. Cleaving double-stranded DNA with peptide nucleic acids
US7517864B2 (en) * 2001-05-18 2009-04-14 Sirna Therapeutics, Inc. RNA interference mediated inhibition of vascular endothelial growth factor and vascular endothelial growth factor receptor gene expression using short interfering nucleic acid (siNA)
EP1539689A2 (en) * 2002-07-19 2005-06-15 Pharmacia Corporation Antisense modulation of endothelial lipase expression
AU2003295600A1 (en) * 2002-11-14 2004-06-15 Dharmacon, Inc. Functional and hyperfunctional sirna
EP2933332A1 (en) * 2004-06-28 2015-10-21 The University Of Western Australia Antisense oligonucleotides for inducing exon skipping and methods of use thereof
US8501703B2 (en) * 2005-08-30 2013-08-06 Isis Pharmaceuticals, Inc. Chimeric oligomeric compounds for modulation of splicing
US8178503B2 (en) * 2006-03-03 2012-05-15 International Business Machines Corporation Ribonucleic acid interference molecules and binding sites derived by analyzing intergenic and intronic regions of genomes
WO2015168108A2 (en) * 2014-04-28 2015-11-05 Rxi Pharmaceuticals Corporation Methods for treating cancer using nucleic targeting mdm2 or mycn
EP2985343A1 (en) * 2014-08-11 2016-02-17 Karlsruher Institut für Technologie In vitro-co-culturesystem

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