JP2021533866A - 重度の低酸素血症を改善するための吸入一酸化窒素（ｉＮＯ）の使用 - Google Patents

重度の低酸素血症を改善するための吸入一酸化窒素（ｉＮＯ）の使用 Download PDF

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JP2021533866A
JP2021533866A JP2021506750A JP2021506750A JP2021533866A JP 2021533866 A JP2021533866 A JP 2021533866A JP 2021506750 A JP2021506750 A JP 2021506750A JP 2021506750 A JP2021506750 A JP 2021506750A JP 2021533866 A JP2021533866 A JP 2021533866A
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ino
delivered
patient
oxygen saturation
dose
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JP2021533866A5 (https=
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シャー，パラグ
クイン，デボラ
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ベレロフォン・セラピューティクス
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. ventilators; Tracheal tubes
    • A61M16/021—Devices for influencing the respiratory system of patients by gas treatment, e.g. ventilators; Tracheal tubes operated by electrical means
    • A61M16/022—Control means therefor
    • A61M16/024—Control means therefor including calculation means, e.g. using a processor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/08—Inhaling devices inserted into the nose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. ventilators; Tracheal tubes
    • A61M16/06—Respiratory or anaesthetic masks
    • A61M16/0666—Nasal cannulas or tubing
    • A61M16/0672—Nasal cannula assemblies for oxygen therapy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. ventilators; Tracheal tubes
    • A61M16/10—Preparation of respiratory gases or vapours
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. ventilators; Tracheal tubes
    • A61M16/10—Preparation of respiratory gases or vapours
    • A61M16/1005—Preparation of respiratory gases or vapours with O2 features or with parameter measurement
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. ventilators; Tracheal tubes
    • A61M16/10—Preparation of respiratory gases or vapours
    • A61M16/12—Preparation of respiratory gases or vapours by mixing different gases
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/08—Measuring devices for evaluating the respiratory organs
    • A61B5/0816—Measuring devices for examining respiratory frequency
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. ventilators; Tracheal tubes
    • A61M16/0003—Accessories therefor, e.g. sensors, vibrators, negative pressure
    • A61M2016/0015—Accessories therefor, e.g. sensors, vibrators, negative pressure inhalation detectors
    • A61M2016/0018—Accessories therefor, e.g. sensors, vibrators, negative pressure inhalation detectors electrical
    • A61M2016/0021—Accessories therefor, e.g. sensors, vibrators, negative pressure inhalation detectors electrical with a proportional output signal, e.g. from a thermistor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2202/00—Special media to be introduced, removed or treated
    • A61M2202/02—Gases
    • A61M2202/0208—Oxygen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2202/00—Special media to be introduced, removed or treated
    • A61M2202/02—Gases
    • A61M2202/0266—Nitrogen (N)
    • A61M2202/0275—Nitric oxide [NO]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2230/00—Measuring parameters of the user
    • A61M2230/20—Blood composition characteristics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2230/00—Measuring parameters of the user
    • A61M2230/20—Blood composition characteristics
    • A61M2230/205—Blood composition characteristics partial oxygen pressure (P-O2)

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pulmonology (AREA)
  • Engineering & Computer Science (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Anesthesiology (AREA)
  • Emergency Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Otolaryngology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biophysics (AREA)
  • Physiology (AREA)
  • Physics & Mathematics (AREA)
  • Communicable Diseases (AREA)
  • Pathology (AREA)
  • Medical Informatics (AREA)
  • Molecular Biology (AREA)
  • Surgery (AREA)
  • Oncology (AREA)
  • Inorganic Chemistry (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
JP2021506750A 2018-08-10 2019-08-08 重度の低酸素血症を改善するための吸入一酸化窒素（ｉＮＯ）の使用 Pending JP2021533866A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201862717433P 2018-08-10 2018-08-10
US62/717,433 2018-08-10
PCT/US2019/045806 WO2020033768A1 (en) 2018-08-10 2019-08-08 Use of inhaled nitric oxide (ino) for the improvement of severe hypoxemia

Publications (2)

Publication Number Publication Date
JP2021533866A true JP2021533866A (ja) 2021-12-09
JP2021533866A5 JP2021533866A5 (https=) 2022-08-16

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JP2021506750A Pending JP2021533866A (ja) 2018-08-10 2019-08-08 重度の低酸素血症を改善するための吸入一酸化窒素（ｉＮＯ）の使用

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US (1) US20230158260A1 (https=)
EP (1) EP3833418A4 (https=)
JP (1) JP2021533866A (https=)
CN (1) CN112969491A (https=)
AR (1) AR117632A1 (https=)
AU (2) AU2019319953B2 (https=)
CA (1) CA3108273A1 (https=)
IL (1) IL280444A (https=)
MX (3) MX2021001430A (https=)
TW (1) TW202021637A (https=)
WO (1) WO2020033768A1 (https=)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR112019016708B1 (pt) 2017-02-27 2024-01-30 Third Pole, Inc Sistemas de geração de óxido nítrico
WO2018157175A1 (en) 2017-02-27 2018-08-30 Third Pole, Inc. Systems and methods for ambulatory generation of nitric oxide
MX2020010523A (es) 2017-02-27 2021-02-09 Third Pole Inc Sistemas y metodos para generar oxido nitrico.
CN114269685A (zh) 2019-05-15 2022-04-01 第三极股份有限公司 用于一氧化氮生成的电极
EP3969416A4 (en) 2019-05-15 2023-11-01 Third Pole, Inc. SYSTEMS AND DEVICES FOR GENERATING NITROGEN OXIDE
WO2020232414A1 (en) 2019-05-15 2020-11-19 Third Pole, Inc. Architectures for production of nitric oxide
EP4069069A4 (en) 2020-01-11 2024-07-03 Third Pole, Inc. SYSTEMS AND METHODS FOR NITROGEN OXIDE PRODUCTION WITH HUMIDITY CONTROL
JP2023527463A (ja) * 2020-05-29 2023-06-28 ベレロフォン・セラピューティクス 気体状薬剤のパルス式送達方法
EP4167920A4 (en) 2020-06-18 2024-06-12 Third Pole, Inc. Systems and methods for preventing and treating infections with nitric oxide
WO2022082072A1 (en) 2020-10-16 2022-04-21 Third Pole, Inc. Nitric oxide generation process controls
EP4405019A4 (en) 2021-09-23 2025-07-16 Third Pole Inc SYSTEMS AND METHODS FOR PROVIDING NITRIC OXIDE
WO2023201363A2 (en) 2022-04-14 2023-10-19 Third Pole, Inc. Delivery of medicinal gas in a liquid medium

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2017139113A1 (en) * 2016-02-12 2017-08-17 Mallinckrodt Hospital Products IP Limited Use and monitoring of inhaled nitric oxide with left ventricular assist devices

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5890490A (en) * 1996-11-29 1999-04-06 Aylsworth; Alonzo C. Therapeutic gas flow monitoring system
US20060201504A1 (en) * 2005-03-08 2006-09-14 Singhal Aneesh B High-flow oxygen delivery system and methods of use thereof
US8020558B2 (en) * 2007-01-26 2011-09-20 Cs Medical, Inc. System for providing flow-targeted ventilation synchronized to a patient's breathing cycle
CA2781295C (en) * 2009-11-20 2018-02-13 Geno Llc Nitric oxide delivery system
US20120093948A1 (en) * 2009-11-20 2012-04-19 Fine David H Nitric Oxide Treatments
WO2014160373A1 (en) * 2013-03-13 2014-10-02 Ino Therapeutics Llc Devices and methods for monitoring oxygenation during treatment with delivery of nitric oxide
JP2019506259A (ja) * 2015-12-11 2019-03-07 ベロ バイオテック エルエルシー 線維症に対処するために一酸化窒素を含むガスを投与するための方法及び装置
CA3087195A1 (en) * 2017-12-28 2019-07-04 Bellerophon Pulse Technologies Llc Use of inhaled nitric oxide and oxygen for the treatment of pulmonary hypertension

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2017139113A1 (en) * 2016-02-12 2017-08-17 Mallinckrodt Hospital Products IP Limited Use and monitoring of inhaled nitric oxide with left ventricular assist devices

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Publication number Publication date
CA3108273A1 (en) 2020-02-13
US20230158260A1 (en) 2023-05-25
IL280444A (en) 2021-03-25
MX2025003262A (es) 2025-05-02
MX2021001430A (es) 2021-05-12
AU2019319953A1 (en) 2021-03-11
CN112969491A (zh) 2021-06-15
EP3833418A4 (en) 2022-08-10
AU2019319953B2 (en) 2025-02-27
MX2025006329A (es) 2025-07-01
EP3833418A1 (en) 2021-06-16
AU2025203477A1 (en) 2025-05-29
WO2020033768A1 (en) 2020-02-13
AR117632A1 (es) 2021-08-18
TW202021637A (zh) 2020-06-16

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