JP2021531458A - アッセイ - Google Patents
アッセイ Download PDFInfo
- Publication number
- JP2021531458A JP2021531458A JP2021500951A JP2021500951A JP2021531458A JP 2021531458 A JP2021531458 A JP 2021531458A JP 2021500951 A JP2021500951 A JP 2021500951A JP 2021500951 A JP2021500951 A JP 2021500951A JP 2021531458 A JP2021531458 A JP 2021531458A
- Authority
- JP
- Japan
- Prior art keywords
- specific binding
- binding partner
- analyte
- substituted
- chemiluminescent
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 0 CC(S)=C1c2ccccc2N(*)c2ccccc12 Chemical compound CC(S)=C1c2ccccc2N(*)c2ccccc12 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/26—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving oxidoreductase
- C12Q1/28—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving oxidoreductase involving peroxidase
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/536—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase
- G01N33/542—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase with steric inhibition or signal modification, e.g. fluorescent quenching
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
- G01N33/581—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with enzyme label (including co-enzymes, co-factors, enzyme inhibitors or substrates)
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
- G01N33/582—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with fluorescent label
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Chemical & Material Sciences (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Microbiology (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- Medicinal Chemistry (AREA)
- Food Science & Technology (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Cell Biology (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Wood Science & Technology (AREA)
- Biophysics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862697514P | 2018-07-13 | 2018-07-13 | |
| US62/697,514 | 2018-07-13 | ||
| PCT/IB2019/055896 WO2020012391A1 (en) | 2018-07-13 | 2019-07-10 | Assay |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2021531458A true JP2021531458A (ja) | 2021-11-18 |
| JP2021531458A5 JP2021531458A5 (https=) | 2022-06-10 |
Family
ID=67997657
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021500951A Pending JP2021531458A (ja) | 2018-07-13 | 2019-07-10 | アッセイ |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US12379379B2 (https=) |
| EP (1) | EP3821029A1 (https=) |
| JP (1) | JP2021531458A (https=) |
| CN (1) | CN112400025A (https=) |
| WO (1) | WO2020012391A1 (https=) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN112400113B (zh) * | 2018-07-13 | 2022-04-15 | 3M创新有限公司 | 特异性结合化学发光测定法 |
| CN115078315B (zh) * | 2021-03-12 | 2025-12-26 | 郑州思昆生物工程有限公司 | 抑制荧光强度降低的成像试剂、试剂盒 |
| CN114853738B (zh) * | 2022-04-29 | 2022-11-29 | 广州中医药大学(广州中医药研究院) | 一种鲁米诺衍生物及其制备方法与应用 |
| WO2026046220A1 (zh) * | 2024-08-29 | 2026-03-05 | 中元汇吉生物技术股份有限公司 | 一种多级判断式高精度检测方法与系统及试剂盒 |
| CN119780443A (zh) * | 2024-12-31 | 2025-04-08 | 神州医疗生物科技(北京)有限公司 | 基于空间邻近化学发光的人磷酸化Tau-181蛋白检测方法、试剂盒及应用 |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20060046302A1 (en) * | 2004-08-30 | 2006-03-02 | Springston Stephen R | Quantitative determination of atmospheric hydroperoxyl radical |
| JP2012519285A (ja) * | 2009-02-27 | 2012-08-23 | ベックマン コールター, インコーポレイテッド | 液相ホモジニアスアッセイ |
Family Cites Families (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US523212A (en) | 1894-07-17 | Cleaning attachment | ||
| US4837395A (en) | 1985-05-10 | 1989-06-06 | Syntex (U.S.A.) Inc. | Single step heterogeneous assay |
| DE68911633T2 (de) | 1988-09-30 | 1994-04-07 | Fujirebio Kk | Verfahren zur Bestimmung von Peroxidase-Aktivität unter Verwendung von Chemilumineszenz. |
| EP0422252B1 (en) | 1989-04-28 | 1995-07-26 | Toray Industries, Inc. | Method for detecting a substance using chemiluminescence |
| US5324835A (en) | 1990-03-30 | 1994-06-28 | Biosensor Laboratories Co., Ltd. | Pyridazinoquinoxalinones for use as chemiluminescent agents |
| ES2107465T3 (es) | 1990-06-12 | 1997-12-01 | British Tech Group | Ensayo antioxidante. |
| CA2056142A1 (en) | 1990-11-27 | 1992-05-28 | Hirotomo Masuya | Pyridopyridazine compounds and their use |
| US6251581B1 (en) | 1991-05-22 | 2001-06-26 | Dade Behring Marburg Gmbh | Assay method utilizing induced luminescence |
| US5444590A (en) | 1992-12-04 | 1995-08-22 | Texas Instruments Incorporated | Solid state power controller with power switch protection apparatus |
| US5512451A (en) | 1993-04-01 | 1996-04-30 | British Technology Group Limited | Enhancement of chemiluminescent reactions |
| US5593845A (en) | 1993-05-17 | 1997-01-14 | Lumigen, Inc. | Aryl N-alkylacridancarboxylate derivatives useful for chemiluminescent detection |
| US5523212A (en) | 1993-05-17 | 1996-06-04 | Lumigen, Inc. | Aryl N-alkylacridanthiocarboxylate derivatives useful for chemiluminescent detection |
| US5491072A (en) | 1993-05-17 | 1996-02-13 | Lumigen, Inc. | N-alkylacridan carboxyl derivatives useful for chemiluminescent detection |
| PT915851E (pt) | 1996-07-16 | 2002-09-30 | Staat Nl Verteg Door Min Welzi | Esteres dibenzodihidropiridinecarboxilicos e seu uso no ensaio dos metodos quimiluminiscente |
| US5922588A (en) | 1996-10-04 | 1999-07-13 | Merck & Co., Inc. | Synthetic HPV16 virus-like particles |
| US5922558A (en) | 1997-09-12 | 1999-07-13 | Lumigen, Inc. | Methods and compositions for generating chemiluminescence with a peroxidase |
| AU9102398A (en) | 1997-09-12 | 1999-04-05 | Lumigen, Inc. | Novel compounds for generating chemiluminescence with a peroxidase |
| US6162610A (en) | 1998-09-11 | 2000-12-19 | Tropix, Inc. | Xanthan-ester and acridan substrates for horseradish peroxidase |
| US6764819B2 (en) | 2002-07-16 | 2004-07-20 | Emp Biotech Gmbh | Method for chemiluminescent detection |
| US7682839B2 (en) | 2005-03-14 | 2010-03-23 | Lumigen, Inc. | Methods using novel chemiluminescent labels |
| JP5055289B2 (ja) | 2005-11-17 | 2012-10-24 | シーメンス・ヘルスケア・ダイアグノスティックス・インコーポレイテッド | アッセイにおける非特異的結合の低減 |
| US7799534B2 (en) | 2006-05-09 | 2010-09-21 | Beckman Coulter, Inc. | Nonseparation assay methods |
| US7732153B2 (en) * | 2006-05-09 | 2010-06-08 | Beckman Coulter, Inc. | Nonseparation assay methods |
| CN102333885A (zh) * | 2009-02-27 | 2012-01-25 | 贝克曼考尔特公司 | 使用选择性信号抑制剂的非分离式测定 |
| JP2013532275A (ja) | 2010-05-14 | 2013-08-15 | ベックマン コールター, インコーポレイテッド | 高感度のホモジニアス化学発光アッセイ方法 |
-
2019
- 2019-07-10 WO PCT/IB2019/055896 patent/WO2020012391A1/en not_active Ceased
- 2019-07-10 JP JP2021500951A patent/JP2021531458A/ja active Pending
- 2019-07-10 EP EP19770177.4A patent/EP3821029A1/en active Pending
- 2019-07-10 US US17/258,576 patent/US12379379B2/en active Active
- 2019-07-10 CN CN201980046859.7A patent/CN112400025A/zh active Pending
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20060046302A1 (en) * | 2004-08-30 | 2006-03-02 | Springston Stephen R | Quantitative determination of atmospheric hydroperoxyl radical |
| JP2012519285A (ja) * | 2009-02-27 | 2012-08-23 | ベックマン コールター, インコーポレイテッド | 液相ホモジニアスアッセイ |
Also Published As
| Publication number | Publication date |
|---|---|
| US12379379B2 (en) | 2025-08-05 |
| WO2020012391A1 (en) | 2020-01-16 |
| CN112400025A (zh) | 2021-02-23 |
| EP3821029A1 (en) | 2021-05-19 |
| US20210270838A1 (en) | 2021-09-02 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2021531458A (ja) | アッセイ | |
| USRE49466E1 (en) | Solution phase homogeneous assays | |
| US20100273189A1 (en) | Non separation assays with selective signal inhibitors | |
| JP2013532275A (ja) | 高感度のホモジニアス化学発光アッセイ方法 | |
| EP1027604A1 (en) | Extended dynamic range assays | |
| JP7055975B2 (ja) | 特異的結合化学発光アッセイ | |
| KR19990044308A (ko) | 화학발광 시스템의 신호-발생 효소로서의 바나듐 브로모퍼옥시다제의 용도 ; 테스트 키트 및 분석 방법 |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RD03 | Notification of appointment of power of attorney |
Free format text: JAPANESE INTERMEDIATE CODE: A7423 Effective date: 20220415 |
|
| A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20220525 |
|
| A621 | Written request for application examination |
Free format text: JAPANESE INTERMEDIATE CODE: A621 Effective date: 20220525 |
|
| A711 | Notification of change in applicant |
Free format text: JAPANESE INTERMEDIATE CODE: A711 Effective date: 20230419 |
|
| A977 | Report on retrieval |
Free format text: JAPANESE INTERMEDIATE CODE: A971007 Effective date: 20230426 |
|
| A131 | Notification of reasons for refusal |
Free format text: JAPANESE INTERMEDIATE CODE: A131 Effective date: 20231003 |
|
| A601 | Written request for extension of time |
Free format text: JAPANESE INTERMEDIATE CODE: A601 Effective date: 20231128 |
|
| A601 | Written request for extension of time |
Free format text: JAPANESE INTERMEDIATE CODE: A601 Effective date: 20240221 |
|
| A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20240403 |
|
| A131 | Notification of reasons for refusal |
Free format text: JAPANESE INTERMEDIATE CODE: A131 Effective date: 20240723 |
|
| A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20241023 |
|
| A02 | Decision of refusal |
Free format text: JAPANESE INTERMEDIATE CODE: A02 Effective date: 20250204 |
|
| A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20250604 |