CN112400025A - 测定 - Google Patents

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Publication number
CN112400025A
CN112400025A CN201980046859.7A CN201980046859A CN112400025A CN 112400025 A CN112400025 A CN 112400025A CN 201980046859 A CN201980046859 A CN 201980046859A CN 112400025 A CN112400025 A CN 112400025A
Authority
CN
China
Prior art keywords
specific binding
analyte
binding partner
chemiluminescent
substituted
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201980046859.7A
Other languages
English (en)
Chinese (zh)
Inventor
格雷戈里·W·西顿
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
3M Innovative Properties Co
Original Assignee
3M Innovative Properties Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 3M Innovative Properties Co filed Critical 3M Innovative Properties Co
Publication of CN112400025A publication Critical patent/CN112400025A/zh
Pending legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • G01N33/582—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with fluorescent label
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/26—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving oxidoreductase
    • C12Q1/28—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving oxidoreductase involving peroxidase
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/536—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase
    • G01N33/542—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase with steric inhibition or signal modification, e.g. fluorescent quenching
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • G01N33/581—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with enzyme label (including co-enzymes, co-factors, enzyme inhibitors or substrates)

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Food Science & Technology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Cell Biology (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Wood Science & Technology (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
CN201980046859.7A 2018-07-13 2019-07-10 测定 Pending CN112400025A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201862697514P 2018-07-13 2018-07-13
US62/697,514 2018-07-13
PCT/IB2019/055896 WO2020012391A1 (en) 2018-07-13 2019-07-10 Assay

Publications (1)

Publication Number Publication Date
CN112400025A true CN112400025A (zh) 2021-02-23

Family

ID=67997657

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201980046859.7A Pending CN112400025A (zh) 2018-07-13 2019-07-10 测定

Country Status (5)

Country Link
US (1) US12379379B2 (https=)
EP (1) EP3821029A1 (https=)
JP (1) JP2021531458A (https=)
CN (1) CN112400025A (https=)
WO (1) WO2020012391A1 (https=)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN114853738A (zh) * 2022-04-29 2022-08-05 广州中医药大学(广州中医药研究院) 一种鲁米诺衍生物及其制备方法与应用
CN115078315A (zh) * 2021-03-12 2022-09-20 郑州思昆生物工程有限公司 抑制荧光强度降低的成像试剂、试剂盒
CN119780443A (zh) * 2024-12-31 2025-04-08 神州医疗生物科技(北京)有限公司 基于空间邻近化学发光的人磷酸化Tau-181蛋白检测方法、试剂盒及应用

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112400113B (zh) * 2018-07-13 2022-04-15 3M创新有限公司 特异性结合化学发光测定法
WO2026046220A1 (zh) * 2024-08-29 2026-03-05 中元汇吉生物技术股份有限公司 一种多级判断式高精度检测方法与系统及试剂盒

Citations (3)

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Publication number Priority date Publication date Assignee Title
US20060046302A1 (en) * 2004-08-30 2006-03-02 Springston Stephen R Quantitative determination of atmospheric hydroperoxyl radical
US20100273189A1 (en) * 2009-02-27 2010-10-28 Beckman Coulter, Inc. Non separation assays with selective signal inhibitors
CN102333886A (zh) * 2009-02-27 2012-01-25 贝克曼考尔特公司 液相均相测定

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US523212A (en) 1894-07-17 Cleaning attachment
US4837395A (en) 1985-05-10 1989-06-06 Syntex (U.S.A.) Inc. Single step heterogeneous assay
DE68911633T2 (de) 1988-09-30 1994-04-07 Fujirebio Kk Verfahren zur Bestimmung von Peroxidase-Aktivität unter Verwendung von Chemilumineszenz.
EP0422252B1 (en) 1989-04-28 1995-07-26 Toray Industries, Inc. Method for detecting a substance using chemiluminescence
US5324835A (en) 1990-03-30 1994-06-28 Biosensor Laboratories Co., Ltd. Pyridazinoquinoxalinones for use as chemiluminescent agents
ES2107465T3 (es) 1990-06-12 1997-12-01 British Tech Group Ensayo antioxidante.
CA2056142A1 (en) 1990-11-27 1992-05-28 Hirotomo Masuya Pyridopyridazine compounds and their use
US6251581B1 (en) 1991-05-22 2001-06-26 Dade Behring Marburg Gmbh Assay method utilizing induced luminescence
US5444590A (en) 1992-12-04 1995-08-22 Texas Instruments Incorporated Solid state power controller with power switch protection apparatus
US5512451A (en) 1993-04-01 1996-04-30 British Technology Group Limited Enhancement of chemiluminescent reactions
US5593845A (en) 1993-05-17 1997-01-14 Lumigen, Inc. Aryl N-alkylacridancarboxylate derivatives useful for chemiluminescent detection
US5523212A (en) 1993-05-17 1996-06-04 Lumigen, Inc. Aryl N-alkylacridanthiocarboxylate derivatives useful for chemiluminescent detection
US5491072A (en) 1993-05-17 1996-02-13 Lumigen, Inc. N-alkylacridan carboxyl derivatives useful for chemiluminescent detection
PT915851E (pt) 1996-07-16 2002-09-30 Staat Nl Verteg Door Min Welzi Esteres dibenzodihidropiridinecarboxilicos e seu uso no ensaio dos metodos quimiluminiscente
US5922588A (en) 1996-10-04 1999-07-13 Merck & Co., Inc. Synthetic HPV16 virus-like particles
US5922558A (en) 1997-09-12 1999-07-13 Lumigen, Inc. Methods and compositions for generating chemiluminescence with a peroxidase
AU9102398A (en) 1997-09-12 1999-04-05 Lumigen, Inc. Novel compounds for generating chemiluminescence with a peroxidase
US6162610A (en) 1998-09-11 2000-12-19 Tropix, Inc. Xanthan-ester and acridan substrates for horseradish peroxidase
US6764819B2 (en) 2002-07-16 2004-07-20 Emp Biotech Gmbh Method for chemiluminescent detection
US7682839B2 (en) 2005-03-14 2010-03-23 Lumigen, Inc. Methods using novel chemiluminescent labels
JP5055289B2 (ja) 2005-11-17 2012-10-24 シーメンス・ヘルスケア・ダイアグノスティックス・インコーポレイテッド アッセイにおける非特異的結合の低減
US7799534B2 (en) 2006-05-09 2010-09-21 Beckman Coulter, Inc. Nonseparation assay methods
US7732153B2 (en) * 2006-05-09 2010-06-08 Beckman Coulter, Inc. Nonseparation assay methods
JP2013532275A (ja) 2010-05-14 2013-08-15 ベックマン コールター， インコーポレイテッド 高感度のホモジニアス化学発光アッセイ方法

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20060046302A1 (en) * 2004-08-30 2006-03-02 Springston Stephen R Quantitative determination of atmospheric hydroperoxyl radical
US20100273189A1 (en) * 2009-02-27 2010-10-28 Beckman Coulter, Inc. Non separation assays with selective signal inhibitors
CN102333886A (zh) * 2009-02-27 2012-01-25 贝克曼考尔特公司 液相均相测定

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN115078315A (zh) * 2021-03-12 2022-09-20 郑州思昆生物工程有限公司 抑制荧光强度降低的成像试剂、试剂盒
CN114853738A (zh) * 2022-04-29 2022-08-05 广州中医药大学(广州中医药研究院) 一种鲁米诺衍生物及其制备方法与应用
CN114853738B (zh) * 2022-04-29 2022-11-29 广州中医药大学(广州中医药研究院) 一种鲁米诺衍生物及其制备方法与应用
CN119780443A (zh) * 2024-12-31 2025-04-08 神州医疗生物科技(北京)有限公司 基于空间邻近化学发光的人磷酸化Tau-181蛋白检测方法、试剂盒及应用

Also Published As

Publication number Publication date
JP2021531458A (ja) 2021-11-18
US12379379B2 (en) 2025-08-05
WO2020012391A1 (en) 2020-01-16
EP3821029A1 (en) 2021-05-19
US20210270838A1 (en) 2021-09-02

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