JP2021527123A - 環状ペプチド化合物およびその使用方法 - Google Patents

環状ペプチド化合物およびその使用方法 Download PDF

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Publication number
JP2021527123A
JP2021527123A JP2021518038A JP2021518038A JP2021527123A JP 2021527123 A JP2021527123 A JP 2021527123A JP 2021518038 A JP2021518038 A JP 2021518038A JP 2021518038 A JP2021518038 A JP 2021518038A JP 2021527123 A JP2021527123 A JP 2021527123A
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seq
compound according
cancer
compound
protecting group
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Japanese (ja)
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JP2021527123A5 (https=
Inventor
マーク マクラフリン，
ロリ ヘーズルハースト，
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モジュレーション セラピューティクス， インコーポレイテッド
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Publication of JP2021527123A publication Critical patent/JP2021527123A/ja
Publication of JP2021527123A5 publication Critical patent/JP2021527123A5/ja
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/64—Cyclic peptides containing only normal peptide links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K11/00—Depsipeptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K11/02—Depsipeptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof cyclic, e.g. valinomycins ; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
JP2021518038A 2018-06-05 2019-06-05 環状ペプチド化合物およびその使用方法 Pending JP2021527123A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201862680904P 2018-06-05 2018-06-05
US62/680,904 2018-06-05
PCT/US2019/035652 WO2019236747A2 (en) 2018-06-05 2019-06-05 Cyclic peptide compounds and methods of use thereof

Publications (2)

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JP2021527123A true JP2021527123A (ja) 2021-10-11
JP2021527123A5 JP2021527123A5 (https=) 2022-06-22

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JP2021518038A Pending JP2021527123A (ja) 2018-06-05 2019-06-05 環状ペプチド化合物およびその使用方法

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US (2) US12060438B2 (https=)
EP (1) EP3801592A4 (https=)
JP (1) JP2021527123A (https=)
CA (1) CA3102630A1 (https=)
WO (1) WO2019236747A2 (https=)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN117466788A (zh) * 2023-10-30 2024-01-30 吉尔多肽生物制药(大连市)有限公司 一种Nα-叔丁氧羰基-L-半胱氨酸的合成方法

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2010022089A2 (en) * 2008-08-18 2010-02-25 University Of Maryland, Baltimore Derivatives of apf and methods of use
US20160229892A1 (en) * 2013-09-27 2016-08-11 H. Lee Moffitt Cancer Center And Research Institute, Inc. Cyclic peptide conjugates and methods of use
US20160257712A1 (en) * 2010-03-19 2016-09-08 H. Lee Moffitt Cancer Center And Research Institute, Inc. Integrin interaction inhibitors for the treatment of cancer
US20170174726A1 (en) * 2014-03-31 2017-06-22 H. Lee Moffitt Cancer Center And Research Institute, Inc. Stabilized peptoid-peptide hybrids and uses thereof

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20150071918A1 (en) * 2012-05-09 2015-03-12 H. Lee Moffitt Cancer Center And Research Institute, Inc. Peptides for the treatment of cancer
US20140322227A1 (en) 2013-04-26 2014-10-30 H. Lee Moffitt Cancer Center & Research Institute, Inc. Peptides for treatment of bone deficiency and autoimmune disorders

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2010022089A2 (en) * 2008-08-18 2010-02-25 University Of Maryland, Baltimore Derivatives of apf and methods of use
US20160257712A1 (en) * 2010-03-19 2016-09-08 H. Lee Moffitt Cancer Center And Research Institute, Inc. Integrin interaction inhibitors for the treatment of cancer
US20160229892A1 (en) * 2013-09-27 2016-08-11 H. Lee Moffitt Cancer Center And Research Institute, Inc. Cyclic peptide conjugates and methods of use
US20170174726A1 (en) * 2014-03-31 2017-06-22 H. Lee Moffitt Cancer Center And Research Institute, Inc. Stabilized peptoid-peptide hybrids and uses thereof

Also Published As

Publication number Publication date
EP3801592A2 (en) 2021-04-14
CA3102630A1 (en) 2019-12-12
US20210347826A1 (en) 2021-11-11
WO2019236747A3 (en) 2020-01-23
WO2019236747A2 (en) 2019-12-12
EP3801592A4 (en) 2022-04-27
US20250136642A1 (en) 2025-05-01
US12060438B2 (en) 2024-08-13

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