JP2021523103A5 - - Google Patents

Info

Publication number
JP2021523103A5
JP2021523103A5 JP2020560900A JP2020560900A JP2021523103A5 JP 2021523103 A5 JP2021523103 A5 JP 2021523103A5 JP 2020560900 A JP2020560900 A JP 2020560900A JP 2020560900 A JP2020560900 A JP 2020560900A JP 2021523103 A5 JP2021523103 A5 JP 2021523103A5
Authority
JP
Japan
Prior art keywords
composition according
fibrosis
extracellular matrix
nanovesicles
composition
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2020560900A
Other languages
English (en)
Japanese (ja)
Other versions
JP2021523103A (ja
JP7548567B2 (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2019/030547 external-priority patent/WO2019213482A1/en
Publication of JP2021523103A publication Critical patent/JP2021523103A/ja
Publication of JP2021523103A5 publication Critical patent/JP2021523103A5/ja
Priority to JP2024140826A priority Critical patent/JP2024159910A/ja
Application granted granted Critical
Publication of JP7548567B2 publication Critical patent/JP7548567B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

JP2020560900A 2018-05-03 2019-05-03 Il-33を含有するマトリックス結合型小胞(mbvs)およびそれらの使用 Active JP7548567B2 (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2024140826A JP2024159910A (ja) 2018-05-03 2024-08-22 Il-33を含有するマトリックス結合型小胞(mbvs)およびそれらの使用

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201862666624P 2018-05-03 2018-05-03
US62/666,624 2018-05-03
PCT/US2019/030547 WO2019213482A1 (en) 2018-05-03 2019-05-03 Matrix bound vesicles (mbvs) containing il-33 and their use

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2024140826A Division JP2024159910A (ja) 2018-05-03 2024-08-22 Il-33を含有するマトリックス結合型小胞(mbvs)およびそれらの使用

Publications (3)

Publication Number Publication Date
JP2021523103A JP2021523103A (ja) 2021-09-02
JP2021523103A5 true JP2021523103A5 (https=) 2022-04-27
JP7548567B2 JP7548567B2 (ja) 2024-09-10

Family

ID=68386862

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2020560900A Active JP7548567B2 (ja) 2018-05-03 2019-05-03 Il-33を含有するマトリックス結合型小胞(mbvs)およびそれらの使用
JP2024140826A Pending JP2024159910A (ja) 2018-05-03 2024-08-22 Il-33を含有するマトリックス結合型小胞(mbvs)およびそれらの使用

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2024140826A Pending JP2024159910A (ja) 2018-05-03 2024-08-22 Il-33を含有するマトリックス結合型小胞(mbvs)およびそれらの使用

Country Status (8)

Country Link
US (1) US12440444B2 (https=)
EP (1) EP3787642A4 (https=)
JP (2) JP7548567B2 (https=)
KR (1) KR20210005942A (https=)
CN (1) CN112805016A (https=)
AU (2) AU2019263479B2 (https=)
CA (1) CA3098149A1 (https=)
WO (1) WO2019213482A1 (https=)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2015231110B2 (en) 2014-03-21 2019-03-07 University Of Pittsburgh - Of The Commonwealth System Of Higher Education Methods for preparation of a terminally sterilized hydrogel derived from extracellular matrix
CA3049990A1 (en) 2017-03-02 2018-09-07 University Of Pittsburgh - Of The Commonwealth System Of Higher Education Extracellular matrix (ecm) hydrogel and soluble fraction thereof for the treatment of cancer
EP3589292B1 (en) 2017-03-02 2023-08-23 University of Pittsburgh - Of the Commonwealth System of Higher Education Ecm hydrogel for treating esophageal inflammation
KR102872720B1 (ko) 2017-05-05 2025-10-16 유니버시티 오브 피츠버그 - 오브 더 커먼웰쓰 시스템 오브 하이어 에듀케이션 기질 결합 소낭의 안구에의 적용
US20240226170A9 (en) * 2019-10-23 2024-07-11 University Of Pittsburgh - Of The Commonwealth System Of Higher Education Use of mbv for treating autoimmune disease
JP2023514821A (ja) 2020-02-28 2023-04-11 テキサス メディカル センター 癒着阻止および組織治癒向上のための噴霧可能刺激応答性マイクロヒドロゲル
EP4135727A4 (en) * 2020-04-16 2024-05-22 University of Pittsburgh - of the Commonwealth System of Higher Education MATRIX-BOUND VESICLES (MBV) FOR THE TREATMENT OF ACUTE RESPIRATORY DISTRESS SYNDROME
US20230210898A1 (en) * 2020-04-24 2023-07-06 University Of Pittsburgh - Of The Commonwealth System Of Higher Education Microparticle-Assisted Treg Therapy for Treatment of Tissue Injury and Fibrosis
AU2023249793A1 (en) * 2022-04-08 2024-11-21 University Of Pittsburgh - Of The Commonwealth System Of Higher Education Matrix bound nanovesicles encapsulated in hydrogels
EP4712988A1 (en) * 2023-05-17 2026-03-25 University Of Pittsburgh - Of The Commonwealth System Of Higher Education Methods for treating muscle wasting diseases using mbv
CN118416023B (zh) * 2024-05-07 2025-01-28 山东大学 用于特发性肺纤维化治疗的仿生纳米递送系统m@rcpda纳米粒及其制备方法
CN119033723B (zh) * 2024-08-15 2025-05-02 南京鼓楼医院 一种氨氯地平药物靶向递送系统及其制备方法和应用

Family Cites Families (68)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4978668A (en) 1986-09-02 1990-12-18 Purdue Research Foundation Treatment to reduce ischemic tissue injury
US4956178A (en) 1988-07-11 1990-09-11 Purdue Research Foundation Tissue graft composition
US4902508A (en) 1988-07-11 1990-02-20 Purdue Research Foundation Tissue graft composition
US5007927A (en) 1989-10-24 1991-04-16 Purdue Research Foundation Muscle-powered cardiac assist device
US5281422A (en) 1991-09-24 1994-01-25 Purdue Research Foundation Graft for promoting autogenous tissue growth
US5352463A (en) 1992-11-13 1994-10-04 Badylak Steven F Tissue graft for surgical reconstruction of a collagenous meniscus and method therefor
US5275826A (en) 1992-11-13 1994-01-04 Purdue Research Foundation Fluidized intestinal submucosa and its use as an injectable tissue graft
US6653291B1 (en) 1992-11-13 2003-11-25 Purdue Research Foundation Composition and method for production of transformed cells
US5641518A (en) 1992-11-13 1997-06-24 Purdue Research Foundation Method of repairing bone tissue
US5695998A (en) 1995-02-10 1997-12-09 Purdue Research Foundation Submucosa as a growth substrate for islet cells
US6485723B1 (en) 1995-02-10 2002-11-26 Purdue Research Foundation Enhanced submucosal tissue graft constructs
WO1996031232A1 (en) 1995-04-07 1996-10-10 Purdue Research Foundation Tissue graft and method for urinary bladder reconstruction
US5711969A (en) 1995-04-07 1998-01-27 Purdue Research Foundation Large area submucosal tissue graft constructs
US5554389A (en) 1995-04-07 1996-09-10 Purdue Research Foundation Urinary bladder submucosa derived tissue graft
CA2160647C (en) 1995-10-16 2002-05-28 Thomas William Garay Helical bearing anchor catcher
US5755791A (en) 1996-04-05 1998-05-26 Purdue Research Foundation Perforated submucosal tissue graft constructs
DK0925067T3 (da) 1996-09-16 2004-05-03 Purdue Research Foundation Graft fra submucosavæv til reparation af neurologisk væv
WO1998019719A1 (en) 1996-11-05 1998-05-14 Purdue Research Foundation Myocardial graft constructs
DE69720252T2 (de) 1996-12-10 2003-12-04 Purdue Research Foundation, West Lafayette Gewebetransplantat aus der magensubmukosa
ATE249182T1 (de) 1996-12-10 2003-09-15 Purdue Research Foundation Rohrförmige transplantatkonstruktionen aus submucosalem gewebe
JP2001505807A (ja) 1996-12-10 2001-05-08 パーデュー・リサーチ・ファウンデーション 人工血管弁
JP4046358B2 (ja) 1996-12-10 2008-02-13 パーデュー・リサーチ・ファウンデーション 粘膜下組織抽出物
US6696270B2 (en) 1996-12-10 2004-02-24 Purdue Research Foundation Gastric submucosal tissue as a novel diagnostic tool
AU732726B2 (en) 1996-12-10 2001-04-26 Purdue Research Foundation Biomaterial derived from vertebrate liver tissue
WO2000015765A1 (en) 1998-09-11 2000-03-23 Purdue Research Foundation Enhanced submucosal tissue graft constructs
GB2361187A (en) 1998-12-01 2001-10-17 Purdue Research Foundation Submucosa modulation of mammalian immune response
US6918396B1 (en) 1998-12-01 2005-07-19 Purdue Research Foundation Method for vocal cord reconstruction
GB2360948B (en) 1998-12-01 2003-12-10 Purdue Research Foundation Composition suitable for vocal cord reconstruction
US6576265B1 (en) 1999-12-22 2003-06-10 Acell, Inc. Tissue regenerative composition, method of making, and method of use thereof
US6579538B1 (en) 1999-12-22 2003-06-17 Acell, Inc. Tissue regenerative compositions for cardiac applications, method of making, and method of use thereof
US20090053279A1 (en) 1999-12-22 2009-02-26 Badylak Stephen F Tissue regenerative composition
EP1503652A4 (en) 2002-05-02 2006-02-08 Purdue Research Foundation HYBRID GRAFTS WITH IMPROVED VASCULARIZATION
CN1665527A (zh) 2002-05-02 2005-09-07 普渡研究基金会 血管化增强的移植构造物
WO2003092381A1 (en) 2002-05-02 2003-11-13 Purdue Research Foundation Vascularization enhanced graft constructs
US20040191226A1 (en) 2002-12-04 2004-09-30 Badylak Stephen F. Method for repair of body wall
US20040187877A1 (en) 2002-12-04 2004-09-30 Badylak Stephen F. Method for repair of liver tissue
US20040176855A1 (en) 2003-03-07 2004-09-09 Acell, Inc. Decellularized liver for repair of tissue and treatment of organ deficiency
US20040175366A1 (en) 2003-03-07 2004-09-09 Acell, Inc. Scaffold for cell growth and differentiation
CA2530490A1 (en) 2003-06-25 2005-01-13 Stephen F. Badylak Conditioned matrix compositions for tissue restoration
NZ549040A (en) * 2004-02-17 2009-07-31 Schering Corp Use for interleukin-33 (IL33) and the IL-33 receptor complex
WO2007084278A2 (en) 2006-01-06 2007-07-26 University Of Pittsburgh-Of The Commonwealth System Of Higher Education Extracellular matrix based gastroesophageal junction reinforcement device
WO2008008266A2 (en) 2006-07-07 2008-01-17 University Of Pittsburgh- Of The Commonwealth System Of Higher Education Biohybrid elastomeric scaffolds and methods of use thereof
US8361503B2 (en) 2007-03-02 2013-01-29 University of Pittsburgh—of the Commonwealth System of Higher Education Extracellular matrix-derived gels and related methods
US20110184439A1 (en) 2008-05-09 2011-07-28 University Of Pittsburgh-Of The Commonwealth System Of Higher Education Biological Matrix for Cardiac Repair
BRPI1008628A2 (pt) 2009-02-18 2016-03-01 Cormatrix Cardiovascular Inc método de tratamento ou prevenção de arritmia cardíaca em um indivíduo
WO2010099463A2 (en) 2009-02-27 2010-09-02 University Of Pittsburgh-Of The Commonwealth System Of Higher Education Joint bioscaffolds
US9814744B2 (en) 2009-12-22 2017-11-14 University of Pittsburg—Of the Commonwealth System of Higher Education Decellularized adipose cell growth scaffold
US9421307B2 (en) 2010-08-17 2016-08-23 University of Pittsburgh—of the Commonwealth System of Higher Education Biohybrid composite scaffold
AU2011293386B2 (en) 2010-08-24 2014-08-21 The Regents Of The University Of California Compositions and methods for cardiac therapy
SG183579A1 (en) 2011-02-11 2012-09-27 Agency Science Tech & Res Methods of detecting therapeutic exosomes
WO2013009595A2 (en) 2011-07-08 2013-01-17 University Of Pittsburgh - Of The Commonwealth System Of Higher Education Injectable cns-derived ecm for tissue reconstruction
ES2703785T3 (es) 2013-04-08 2019-03-12 Regentys Corp Método y composición para tratar una enfermedad inflamatoria intestinal sin colectomía
US9861662B2 (en) 2013-07-03 2018-01-09 University of Pittsburgh—of the Commonwealth System of Higher Education Bone-derived extra cellular matrix gel
US10286119B2 (en) 2014-01-24 2019-05-14 University of Pittsburgh—of the Commonwealth System of Higher Education Extracellular matrix mesh coating
AU2015231110B2 (en) 2014-03-21 2019-03-07 University Of Pittsburgh - Of The Commonwealth System Of Higher Education Methods for preparation of a terminally sterilized hydrogel derived from extracellular matrix
WO2015164728A1 (en) 2014-04-24 2015-10-29 University Of Pittsburgh - Of The Commonwealth System Of Higher Education Fractionating extracellular matrix to modulate bioactivity and the host response
DK3145493T3 (da) 2014-05-18 2022-10-31 Childrens Medical Center Fremgangsmåder og sammensætninger vedrørende exosomer
JP7468983B2 (ja) 2015-06-03 2024-04-16 ウィスコンシン アラムニ リサーチ ファンデーション 虚血性疾患または虚血性損傷を処置するための心臓線維芽細胞由来細胞外マトリックスおよびその注射可能製剤
EP3319653A4 (en) 2015-07-10 2019-03-27 University of Pittsburgh - Of the Commonwealth System of Higher Education METHOD FOR PRODUCING ECM EQUIPMENT AND HYDROGELS FROM COLON
EP3347063B1 (en) 2015-09-10 2025-11-19 University of Pittsburgh - of the Commonwealth System of Higher Education Bi-layer extra cellular matrix scaffolds and uses therefor
EP3349814B1 (en) 2015-09-18 2021-03-17 University of Pittsburgh- Of the Commonwealth System of Higher Education Non-gelling soluble extracellular matrix with biological activity
CA3011294A1 (en) 2016-01-13 2017-07-20 University Of Pittsburgh - Of The Commonwealth System Of Higher Education Vascular extracellular matrix hydrogel
AU2017227790B2 (en) * 2016-03-02 2023-03-16 University Of Pittsburgh - Of The Commonwealth System Of Higher Education Matrix bound nanovesicles and their use
JP2019513038A (ja) 2016-03-14 2019-05-23 リージェンティーズ コーポレイション 炎症性腸疾患を処置するための方法および組成物
EP3589292B1 (en) 2017-03-02 2023-08-23 University of Pittsburgh - Of the Commonwealth System of Higher Education Ecm hydrogel for treating esophageal inflammation
CA3049990A1 (en) 2017-03-02 2018-09-07 University Of Pittsburgh - Of The Commonwealth System Of Higher Education Extracellular matrix (ecm) hydrogel and soluble fraction thereof for the treatment of cancer
US11389569B2 (en) 2017-04-03 2022-07-19 University of Pittsburgh—of the Commonwealth System of Higher Education Biodegradable, porous, thermally responsive injectable hydrogel as soft tissue defect filler
KR102872720B1 (ko) 2017-05-05 2025-10-16 유니버시티 오브 피츠버그 - 오브 더 커먼웰쓰 시스템 오브 하이어 에듀케이션 기질 결합 소낭의 안구에의 적용

Similar Documents

Publication Publication Date Title
JP2021523103A5 (https=)
Fuke et al. Impaired endothelial vasomotor function after sirolimus-eluting stent implantation
Kishon et al. Mitral valve operation in postinfarction rupture of a papillary muscle: immediate results and long-term follow-up of 22 patients
Shantsila et al. Endothelial progenitor cells in cardiovascular disorders
AU2018213671B2 (en) Therapeutic agent for cardiomyopathy, old myocardial infarction and chronic heart failure
JP2021523103A (ja) Il−33を含有するマトリックス結合型小胞(mbvs)およびそれらの使用
CN101925362A (zh) 利用两种或更多种肝细胞生长因子同工型来治疗或预防心脏病症
Sezai et al. Efficacy of continuous low-dose hANP administration in patients undergoing emergent coronary artery bypass grafting for acute coronary syndrome
O'Rourke et al. Efficacy and safety of fluvastatin therapy for hypercholesterolemia after heart transplantation: results of a randomised double blind placebo controlled study
Suzuki et al. Clinical characteristics and follow-up in patients with microvascular angina
Bourgault et al. A most unusual acute coronary syndrome
EP1853296B1 (fr) Utilisation d'un undécapeptide cyclique pour la préparation d'un médicament administrable lors de situations ischémiques myocardiaques
JP2024540172A5 (https=)
Kragel et al. Coronary Arterial Morphology 10 Years After “Endarterectomy”
Jurcut et al. Between Scylla and Charybdis: long-term cardiovascular complications after radiotherapy for Hodgkin's lymphoma
Umei et al. Sudden cardiac death due to ventricular fibrillation in a case of giant cell myocarditis
Yoshida et al. Temporary ventricular overdrive pacing for electrical storm after coronary artery bypass grafting
Ueshima et al. Recovery of atrial function after combined treatment with surgical repair for organic heart disease and maze procedure for atrial fibrillation
Anton et al. Iron deficiency in chronic heart failure
Said et al. Pacing for conduction disturbances in Steinert's disease: a new indication for biventricular ICD?
Paleček et al. Czech Inflammatory Cardiomyopathy Immunosuppression Trial (CZECH-ICIT): randomized, multicentric study comparing the effect of two regimens of combined immunosuppressive therapy in the treatment of inflammatory cardiomyopathy: the aims and design of the trial
Arias-Godínez et al. A case of transient mitral regurgitation: Not everything is always what it seems
Kragel et al. Coronary arterial morphology 10 years after “endarterectomy”
Ramírez et al. Personalized surgical treatment options for anomalous origin of right coronary artery: Two case reports
Arifi et al. Coronary insufficiency in children: Review of literature and report of a rare case with unknown aetiology