JP2021514185A5 - - Google Patents

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Publication number
JP2021514185A5
JP2021514185A5 JP2020543276A JP2020543276A JP2021514185A5 JP 2021514185 A5 JP2021514185 A5 JP 2021514185A5 JP 2020543276 A JP2020543276 A JP 2020543276A JP 2020543276 A JP2020543276 A JP 2020543276A JP 2021514185 A5 JP2021514185 A5 JP 2021514185A5
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JP
Japan
Prior art keywords
cells
notch ligand
cell
positive
cell lineage
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Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2020543276A
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English (en)
Japanese (ja)
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JP2021514185A (ja
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Application filed filed Critical
Priority claimed from PCT/CA2019/050181 external-priority patent/WO2019157597A1/en
Publication of JP2021514185A publication Critical patent/JP2021514185A/ja
Publication of JP2021514185A5 publication Critical patent/JP2021514185A5/ja
Priority to JP2023191915A priority Critical patent/JP7866537B2/ja
Priority to JP2025216743A priority patent/JP2026031647A/ja
Pending legal-status Critical Current

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JP2020543276A 2018-02-14 2019-02-14 T細胞系列の細胞を発生させるための方法 Pending JP2021514185A (ja)

Priority Applications (2)

Application Number Priority Date Filing Date Title
JP2023191915A JP7866537B2 (ja) 2018-02-14 2023-11-10 T細胞系列の細胞を発生させるための方法
JP2025216743A JP2026031647A (ja) 2018-02-14 2025-12-02 T細胞系列の細胞を発生させるための方法

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201862630497P 2018-02-14 2018-02-14
US62/630,497 2018-02-14
PCT/CA2019/050181 WO2019157597A1 (en) 2018-02-14 2019-02-14 Method for generating cells of the t cell lineage

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2023191915A Division JP7866537B2 (ja) 2018-02-14 2023-11-10 T細胞系列の細胞を発生させるための方法

Publications (2)

Publication Number Publication Date
JP2021514185A JP2021514185A (ja) 2021-06-10
JP2021514185A5 true JP2021514185A5 (cg-RX-API-DMAC7.html) 2022-02-10

Family

ID=67619677

Family Applications (3)

Application Number Title Priority Date Filing Date
JP2020543276A Pending JP2021514185A (ja) 2018-02-14 2019-02-14 T細胞系列の細胞を発生させるための方法
JP2023191915A Active JP7866537B2 (ja) 2018-02-14 2023-11-10 T細胞系列の細胞を発生させるための方法
JP2025216743A Pending JP2026031647A (ja) 2018-02-14 2025-12-02 T細胞系列の細胞を発生させるための方法

Family Applications After (2)

Application Number Title Priority Date Filing Date
JP2023191915A Active JP7866537B2 (ja) 2018-02-14 2023-11-10 T細胞系列の細胞を発生させるための方法
JP2025216743A Pending JP2026031647A (ja) 2018-02-14 2025-12-02 T細胞系列の細胞を発生させるための方法

Country Status (8)

Country Link
US (2) US12467034B2 (cg-RX-API-DMAC7.html)
EP (1) EP3752602A4 (cg-RX-API-DMAC7.html)
JP (3) JP2021514185A (cg-RX-API-DMAC7.html)
KR (1) KR20200121817A (cg-RX-API-DMAC7.html)
CN (1) CN112041431A (cg-RX-API-DMAC7.html)
AU (2) AU2019220935B2 (cg-RX-API-DMAC7.html)
CA (1) CA3091158A1 (cg-RX-API-DMAC7.html)
WO (1) WO2019157597A1 (cg-RX-API-DMAC7.html)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA3091158A1 (en) 2018-02-14 2019-08-22 Sunnybrook Research Institute Method for generating cells of the t cell lineage
EP4237542A1 (en) * 2020-10-28 2023-09-06 Sangamo Therapeutics, Inc. Generation of cd4+ effector and regulatory t cells from human pluripotent stem cells
AU2021386370A1 (en) 2020-11-24 2023-06-22 Lyell Immunopharma, Inc. Methods for making, compositions comprising, and methods of using rejuvenated t cells
US11661459B2 (en) 2020-12-03 2023-05-30 Century Therapeutics, Inc. Artificial cell death polypeptide for chimeric antigen receptor and uses thereof
IL303269A (en) 2020-12-03 2023-07-01 Century Therapeutics Inc Genetically engineered cells and uses thereof
EP4289940A4 (en) * 2021-02-05 2025-02-26 National University Corporation Kobe University ?? T-CELLS FROM INDUCED PLURIPOTENT STEM CELLS AND PRODUCTION PROCESSES THEREFOR
AU2022253223A1 (en) 2021-04-07 2023-09-28 Century Therapeutics, Inc. Combined artificial cell death/reporter system polypeptide for chimeric antigen receptor cell and uses thereof
CA3210702A1 (en) 2021-04-07 2022-10-13 Century Therapeutics, Inc. Gene transfer vectors and methods of engineering cells
WO2022241558A1 (en) * 2021-05-18 2022-11-24 The University Of British Columbia A method for producing blood progenitor and progenitor t cells, resulting cells and methods and uses thereof
WO2023129937A1 (en) 2021-12-29 2023-07-06 Century Therapeutics, Inc. Genetically engineered cells having anti-cd19 / anti-cd22 chimeric antigen receptors, and uses thereof
IL314801A (en) 2022-02-22 2024-10-01 Juno Therapeutics Inc Proteinase 3 (PR3) Chimeric Autoantigen Receptor T Cells and Related Methods and Uses
JP2025515095A (ja) 2022-05-04 2025-05-13 センチュリー セラピューティクス,インコーポレイテッド Hla-eおよびhla-g導入遺伝子を用いて操作された細胞
US20250090582A1 (en) 2022-06-08 2025-03-20 Century Therapeutics, Inc. Genetically engineered cells having anti-cd133 / anti-egfr chimeric antigen receptors, and uses thereof
EP4536814A1 (en) 2022-06-08 2025-04-16 Century Therapeutics, Inc. Immunoeffector cells derived from induced pluripotent stem cells genetically engineered with membrane bound il12 and uses thereof
CN119630695A (zh) 2022-06-08 2025-03-14 世纪治疗股份有限公司 表达cd16变体和nkg2d的遗传工程化细胞及其用途
WO2024102838A1 (en) 2022-11-09 2024-05-16 Century Therapeutics, Inc. Engineered interleukin-7 receptors and uses thereof
CN120435498A (zh) 2022-11-10 2025-08-05 世纪治疗股份有限公司 具有抗-nectin4嵌合抗原受体的基因工程化细胞及其用途
KR20250150555A (ko) * 2023-01-27 2025-10-20 노치 테라퓨틱스 (캐나다) 인크. 줄기세포/전구세포로부터 t 세포 계통 모집단을 생성하는 방법
WO2025101938A2 (en) 2023-11-10 2025-05-15 Century Therapeutics, Inc. Genetically engineered cells having multi-transmembrane domain chimeric antigen receptors utilizing g protein-coupled receptor scaffolds, and uses thereof
WO2025106626A1 (en) 2023-11-15 2025-05-22 Century Therapeutics, Inc. Genetically engineered cells expressing c-x-c chemokine receptor type 4, and uses thereof
WO2025207795A1 (en) 2024-03-26 2025-10-02 Juno Therapeutics, Inc. Genetically engineered cells having anti-cd33 / anti-cd123 chimeric antigen receptors, and uses thereof
WO2025207798A1 (en) 2024-03-26 2025-10-02 Century Therapeutics, Inc. Genetically engineered cells having anti-cd123 chimeric antigen receptors, and uses thereof
US20250332260A1 (en) 2024-04-10 2025-10-30 Garuda Therapeutics, Inc. Immune compatible cells for allogeneic cell therapies to cover global, ethnic, or disease-specific populations
US20260083778A1 (en) * 2024-09-20 2026-03-26 Boston Medical Center Corporation Generation of cd4 t cells

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW201043699A (en) 2002-03-25 2010-12-16 Takara Bio Inc Process for producing cytotoxic lymphocyte
EP1492816A2 (en) * 2002-04-05 2005-01-05 Lorantis Limited Modulators of the notch signalling pathway and uses thereof in medical treatment
US7575925B2 (en) * 2002-12-10 2009-08-18 Sunnybrook Health Sciences Centre Cell preparations comprising cells of the T cell lineage and methods of making and using them
WO2004064863A1 (en) 2003-01-23 2004-08-05 Lorantis Limited Treatment of autoimmune diseases using an activator for the notch signaling pathway
WO2007027226A2 (en) * 2005-04-28 2007-03-08 Board Of Regents, The University Of Texas System Systems and methods for the production of differentiated cells
EP2321407A4 (en) 2008-09-11 2012-07-18 Univ Florida SYSTEM AND METHOD FOR THE PRODUCTION OF T-CELLS
US8772028B2 (en) * 2008-11-07 2014-07-08 Sunnybrook Health Sciences Centre CD34+CD7+CD5+CD1a-human progenitor T-cells produced in vitro and methods of using
US8871510B2 (en) 2009-12-03 2014-10-28 University Of Utah Research Foundation Methods for generating T lymphocytes from hematopoietic stem cells
PL2539441T3 (pl) 2010-02-22 2017-06-30 Université Pierre Et Marie Curie (Paris 6) Podłoże do hodowli komórkowej do wzrostu i różnicowania komórek linii hematopoetycznych
US9834754B2 (en) 2011-11-21 2017-12-05 University Health Network Populations of hematopoietic progenitors and methods of enriching stem cells therefor
JP6449995B2 (ja) * 2014-09-16 2019-01-09 ヒタチ ゾウセン イノバ アクチェンゲゼルシャフト 廃棄物焼却プラントの燃焼チャンバー内で発生するスラグを処理するための方法及び装置
FR3026744B1 (fr) 2014-10-06 2024-04-19 Hopitaux Paris Assist Publique Methode de generation de progeniteurs de cellules t
US10626372B1 (en) * 2015-01-26 2020-04-21 Fate Therapeutics, Inc. Methods and compositions for inducing hematopoietic cell differentiation
WO2016187459A1 (en) 2015-05-20 2016-11-24 The Regents Of The University Of California Method for generating human dendritic cells for immunotherapy
US12076342B2 (en) 2016-04-08 2024-09-03 The Governing Council Of The University Of Toronto Method for generating progenitor t cells from stem and/or progenitor cells and use of same
US20190134169A1 (en) 2016-04-26 2019-05-09 Temple University-Of The Commonwealth System Of Higher Education DLL4-expressing cells and vaccine using the same
ES2931530T3 (es) 2017-02-13 2022-12-30 Hopitaux Paris Assist Publique Método para generar progenitores de células T
CA3091158A1 (en) 2018-02-14 2019-08-22 Sunnybrook Research Institute Method for generating cells of the t cell lineage
EP4326856A4 (en) 2021-04-23 2025-10-08 Sunnybrook Res Inst STEM CELLS COMPRISING AN UNREARRANGED T CELL RECEPTOR (TCR) GENE LOCUS AND METHODS OF USE THEREOF
WO2022241558A1 (en) 2021-05-18 2022-11-24 The University Of British Columbia A method for producing blood progenitor and progenitor t cells, resulting cells and methods and uses thereof

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