JP2021513348A5 - - Google Patents

Info

Publication number
JP2021513348A5
JP2021513348A5 JP2020542885A JP2020542885A JP2021513348A5 JP 2021513348 A5 JP2021513348 A5 JP 2021513348A5 JP 2020542885 A JP2020542885 A JP 2020542885A JP 2020542885 A JP2020542885 A JP 2020542885A JP 2021513348 A5 JP2021513348 A5 JP 2021513348A5
Authority
JP
Japan
Prior art keywords
cells
stem cells
cyclopamine
culturing
retinoic acid
Prior art date
Application number
JP2020542885A
Other languages
English (en)
Japanese (ja)
Other versions
JP2021513348A (ja
JPWO2019157329A5 (https=
JP7426340B2 (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2019/017281 external-priority patent/WO2019157329A1/en
Publication of JP2021513348A publication Critical patent/JP2021513348A/ja
Publication of JP2021513348A5 publication Critical patent/JP2021513348A5/ja
Publication of JPWO2019157329A5 publication Critical patent/JPWO2019157329A5/ja
Application granted granted Critical
Publication of JP7426340B2 publication Critical patent/JP7426340B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

JP2020542885A 2018-02-09 2019-02-08 糖尿病を治療するための膵臓細胞および適用に関連するその生成方法 Active JP7426340B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201862628470P 2018-02-09 2018-02-09
US62/628,470 2018-02-09
PCT/US2019/017281 WO2019157329A1 (en) 2018-02-09 2019-02-08 Pancreatic cells for treating diabetes and methods of generating the same

Publications (4)

Publication Number Publication Date
JP2021513348A JP2021513348A (ja) 2021-05-27
JP2021513348A5 true JP2021513348A5 (https=) 2022-02-15
JPWO2019157329A5 JPWO2019157329A5 (https=) 2022-02-15
JP7426340B2 JP7426340B2 (ja) 2024-02-01

Family

ID=65520455

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2020542885A Active JP7426340B2 (ja) 2018-02-09 2019-02-08 糖尿病を治療するための膵臓細胞および適用に関連するその生成方法

Country Status (10)

Country Link
US (2) US11484554B2 (https=)
EP (1) EP3749752A1 (https=)
JP (1) JP7426340B2 (https=)
KR (2) KR20250048481A (https=)
CN (2) CN111836885B (https=)
AU (2) AU2019218122B2 (https=)
CA (1) CA3090536A1 (https=)
IL (1) IL276565B (https=)
SG (1) SG11202007515XA (https=)
WO (1) WO2019157329A1 (https=)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2021117840A1 (ja) * 2019-12-11 2021-06-17 国立大学法人 東京大学 Myclの一過性発現による増殖可能な膵島前駆細胞様細胞の誘導とインスリン陽性細胞への分化誘導
JP2026505821A (ja) 2023-02-03 2026-02-18 セラクシス,インコーポレーテッド 治療細胞およびそれらに関連する方法
WO2025029826A1 (en) 2023-07-31 2025-02-06 Seraxis, Inc. Modified therapeutics cells and methods relating to the same

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2229434B1 (en) * 2007-11-27 2011-09-07 Lifescan, Inc. Differentiation of human embryonic stem cells
MX349178B (es) * 2008-10-31 2017-07-17 Centocor Ortho Biotech Inc Diferenciación de células madre embrionarias humanas al linaje endocrino pancreático.
US20130029416A1 (en) * 2011-07-22 2013-01-31 Tayaramma Thatava Differentiating induced pluripotent stem cells into glucose-responsive, insulin-secreting progeny
EP2864473B1 (en) * 2012-06-26 2019-08-21 Seraxis, Inc. Stem cells and pancreatic cells useful for the treatment of insulin-dependent diabetes mellitus
CN106536718B (zh) * 2014-05-21 2021-04-27 国立大学法人京都大学 胰芽细胞的制造方法及含有胰芽细胞的胰疾病治疗剂
US11332716B2 (en) * 2015-07-27 2022-05-17 The Regents Of The University Of California Methods and compositions for producing pancreatic beta cells

Similar Documents

Publication Publication Date Title
US20260035672A1 (en) Cell culture platform for single cell sorting and enhanced reprogramming of ipscs
US10266807B2 (en) Methods and compositions for culturing endoderm progenitor cells in suspension
EP3178924B1 (en) Method for proliferation of pancreatic progenitor cells
CN102666853B (zh) 由干细胞向肝细胞的分化诱导方法
EP4063487B1 (en) Amplification and differentiation method for pancreatic cells and use thereof
JP2021513348A5 (https=)
CN110392735A (zh) 胰腺祖细胞的维持和扩增
EP3868870B1 (en) Method for producing stem/precursor cells, by using low molecular weight compound, from cells derived from endodermal tissue or organ
JP7148134B2 (ja) 肝芽細胞から胆管上皮前駆細胞への段階的誘導方法
JPWO2019157329A5 (https=)
Muir et al. Krüppel-like factor 4 overexpression initiates a mesenchymal-to-epithelial transition and redifferentiation of human pancreatic cells following expansion in long term adherent culture
EP3950932B1 (en) Method for producing pluripotent stem cells capable of differentiating into specific cells, and application thereof
WO2025223443A1 (en) Compostions in-vitro generated pancreatic islet-like organoids and methods of making and using thereof
Chen et al. Generation and validation of a iPSC line from a healthy female donor using integration-free Sendai virus reprogramming
Baeyens et al. Generation of beta cells from acinar cells
HK40068498B (zh) 用於单细胞分选与增强ipsc重新编程的细胞培养平台
KR20240131080A (ko) 배외내배엽 줄기세포의 배양용 배지 조성물
US20160230225A1 (en) Markers for differentiation of stem cells into differentiated cell populations
CN121712884A (zh) 卵原细胞或前精原细胞的制造方法
HK40058180B (en) Method for producing stem/precursor cells, by using low molecular weight compound, from cells derived from endodermal tissue or organ
HK40058180A (en) Method for producing stem/precursor cells, by using low molecular weight compound, from cells derived from endodermal tissue or organ
HK1239743A1 (en) Cell culture platform for single cell sorting and enhanced reprogramming of ipscs
HK1191049A (en) Cell culture platform for single cell sorting and enhanced reprogramming of ipscs