JP2021513348A5 - - Google Patents

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Publication number
JP2021513348A5
JP2021513348A5 JP2020542885A JP2020542885A JP2021513348A5 JP 2021513348 A5 JP2021513348 A5 JP 2021513348A5 JP 2020542885 A JP2020542885 A JP 2020542885A JP 2020542885 A JP2020542885 A JP 2020542885A JP 2021513348 A5 JP2021513348 A5 JP 2021513348A5
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JP
Japan
Prior art keywords
cells
stem cells
cyclopamine
culturing
retinoic acid
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Application number
JP2020542885A
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English (en)
Japanese (ja)
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JP7426340B2 (ja
JP2021513348A (ja
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Priority claimed from PCT/US2019/017281 external-priority patent/WO2019157329A1/en
Publication of JP2021513348A publication Critical patent/JP2021513348A/ja
Publication of JP2021513348A5 publication Critical patent/JP2021513348A5/ja
Application granted granted Critical
Publication of JP7426340B2 publication Critical patent/JP7426340B2/ja
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JP2020542885A 2018-02-09 2019-02-08 糖尿病を治療するための膵臓細胞および適用に関連するその生成方法 Active JP7426340B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201862628470P 2018-02-09 2018-02-09
US62/628,470 2018-02-09
PCT/US2019/017281 WO2019157329A1 (en) 2018-02-09 2019-02-08 Pancreatic cells for treating diabetes and methods of generating the same

Publications (3)

Publication Number Publication Date
JP2021513348A JP2021513348A (ja) 2021-05-27
JP2021513348A5 true JP2021513348A5 (enExample) 2022-02-15
JP7426340B2 JP7426340B2 (ja) 2024-02-01

Family

ID=65520455

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2020542885A Active JP7426340B2 (ja) 2018-02-09 2019-02-08 糖尿病を治療するための膵臓細胞および適用に関連するその生成方法

Country Status (11)

Country Link
US (3) US11484554B2 (enExample)
EP (1) EP3749752B1 (enExample)
JP (1) JP7426340B2 (enExample)
KR (2) KR102788426B1 (enExample)
CN (2) CN118853579A (enExample)
AU (2) AU2019218122B2 (enExample)
CA (1) CA3090536A1 (enExample)
ES (1) ES3075244T3 (enExample)
IL (1) IL276565B (enExample)
SG (1) SG11202007515XA (enExample)
WO (1) WO2019157329A1 (enExample)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL293803A (en) * 2019-12-11 2022-08-01 Univ Tokyo Induction of proliferating pancreatic islet-like germ cells by transient expression of mycl and induction of differentiation into insulin-positive cells
AU2022349361A1 (en) * 2021-09-22 2024-03-07 Imagine Pharma Llc Compositions and methods for propogating insulin and glucagon secreting cells from type 1 diabetic pancreatic tissue and therapeutic uses thereof
EP4658761A1 (en) 2023-02-03 2025-12-10 Seraxis, Inc. Therapeutic cells and methods relating to the same
WO2025029826A1 (en) 2023-07-31 2025-02-06 Seraxis, Inc. Modified therapeutics cells and methods relating to the same

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107574142B (zh) * 2007-11-27 2021-07-06 生命扫描有限公司 人胚胎干细胞的分化
JP2012507289A (ja) * 2008-10-31 2012-03-29 ヤンセン バイオテツク，インコーポレーテツド ヒト胚性幹細胞の膵内分泌系への分化
US20130029416A1 (en) * 2011-07-22 2013-01-31 Tayaramma Thatava Differentiating induced pluripotent stem cells into glucose-responsive, insulin-secreting progeny
WO2014004341A1 (en) * 2012-06-26 2014-01-03 Seraxis, Inc. Stem cells and pancreatic cells useful for the treatment of insulin-dependent diabetes mellitus
CN106536718B (zh) * 2014-05-21 2021-04-27 国立大学法人京都大学 胰芽细胞的制造方法及含有胰芽细胞的胰疾病治疗剂
US11332716B2 (en) * 2015-07-27 2022-05-17 The Regents Of The University Of California Methods and compositions for producing pancreatic beta cells

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