JP2021511035A5 - - Google Patents

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Publication number
JP2021511035A5
JP2021511035A5 JP2020539080A JP2020539080A JP2021511035A5 JP 2021511035 A5 JP2021511035 A5 JP 2021511035A5 JP 2020539080 A JP2020539080 A JP 2020539080A JP 2020539080 A JP2020539080 A JP 2020539080A JP 2021511035 A5 JP2021511035 A5 JP 2021511035A5
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Japan
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JP2020539080A
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English (en)
Japanese (ja)
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JP2021511035A (ja
JPWO2019143950A5 (https=
JP7504458B2 (ja
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Priority claimed from PCT/US2019/014211 external-priority patent/WO2019143950A2/en
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JP2020539080A 2018-01-19 2019-01-18 Ａａｖ形質導入と関連付けられる自然免疫応答の阻害のための方法および組成物 Active JP7504458B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201862619468P 2018-01-19 2018-01-19
US62/619,468 2018-01-19
PCT/US2019/014211 WO2019143950A2 (en) 2018-01-19 2019-01-18 Methods and compositions for inhibition of innate immune response associated with aav transduction

Publications (4)

Publication Number Publication Date
JP2021511035A JP2021511035A (ja) 2021-05-06
JP2021511035A5 true JP2021511035A5 (https=) 2022-02-24
JPWO2019143950A5 JPWO2019143950A5 (https=) 2022-02-24
JP7504458B2 JP7504458B2 (ja) 2024-06-24

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JP2020539080A Active JP7504458B2 (ja) 2018-01-19 2019-01-18 Ａａｖ形質導入と関連付けられる自然免疫応答の阻害のための方法および組成物

Country Status (7)

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US (1) US20200340013A1 (https=)
EP (1) EP3740572A4 (https=)
JP (1) JP7504458B2 (https=)
CN (1) CN111918966B (https=)
AU (1) AU2019210190B2 (https=)
CA (1) CA3088538A1 (https=)
WO (1) WO2019143950A2 (https=)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2020270960B2 (en) 2019-04-12 2026-01-29 Ultragenyx Pharmaceutical Inc. Engineered producer cell lines and methods of making and using the same
ES2827599B2 (es) * 2019-11-21 2022-05-05 Fundacion Para La Investigacion Biomedica Del Hospital Univ Nino Jesus Celulas madre mesenquimales para ser usadas como vehiculos de agentes terapeuticos
US20220106609A1 (en) * 2019-12-17 2022-04-07 Nikegen, Llc Paravoviral vectors and methods of making and use thereof
WO2021142130A1 (en) * 2020-01-07 2021-07-15 The University Of North Carolina At Chapel Hill Synthetic adeno-associated virus inverted terminal repeats and methods of their use as promoters
US20250019668A1 (en) * 2021-10-29 2025-01-16 Ultragenyx Pharmaceutical Inc. Engineered cell lines for increased production of recombinant adeno-associated virus (raav)
WO2024123813A1 (en) * 2022-12-05 2024-06-13 The Trustees Of Columbia University In The City Of New York Viral vectors for increasing the specificity of gene expression
CN117701638B (zh) * 2023-12-18 2024-10-18 苏州新芽基因生物技术有限公司 一种抑制残留aav载体质粒和质粒骨架转录活性的方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19959045A1 (de) * 1999-12-07 2001-06-28 Deutsches Krebsforsch MCP-1 exprimierende AAV-Expressionsvektoren und deren therapeutische Verwendung
US20110206639A1 (en) * 2004-04-15 2011-08-25 Christie Vermeulen Replication competent viruses capable of silencing virus inhibitory factor expression
US20110070241A1 (en) 2009-06-30 2011-03-24 Duke University Methods for modulating immune responses to aav gene therapy vectors
WO2014145968A2 (en) * 2013-03-15 2014-09-18 The Regents Of The University Of California Rna interference functions as an antiviral immunity in mammals
EP3242945B1 (en) * 2015-01-07 2021-09-01 Universitat Autònoma de Barcelona Single-vector gene construct comprising insulin and glucokinase genes
US20190000943A1 (en) * 2015-08-13 2019-01-03 Aavet Therapeutics, Llc Aav6 vectors for immunotherapy

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