JP2021502363A5 - - Google Patents

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Publication number
JP2021502363A5
JP2021502363A5 JP2020524879A JP2020524879A JP2021502363A5 JP 2021502363 A5 JP2021502363 A5 JP 2021502363A5 JP 2020524879 A JP2020524879 A JP 2020524879A JP 2020524879 A JP2020524879 A JP 2020524879A JP 2021502363 A5 JP2021502363 A5 JP 2021502363A5
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JP
Japan
Prior art keywords
agent according
hbd
defensin
peptide
defensins
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2020524879A
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English (en)
Japanese (ja)
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JP2021502363A (ja
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Publication date
Application filed filed Critical
Priority claimed from PCT/EP2018/080814 external-priority patent/WO2019092201A2/en
Publication of JP2021502363A publication Critical patent/JP2021502363A/ja
Publication of JP2021502363A5 publication Critical patent/JP2021502363A5/ja
Pending legal-status Critical Current

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JP2020524879A 2017-11-10 2018-11-09 早期産児における粘膜抵抗力および腸／肺機能の成熟 Pending JP2021502363A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP17201002 2017-11-10
EP17201002.7 2017-11-10
PCT/EP2018/080814 WO2019092201A2 (en) 2017-11-10 2018-11-09 Maturation of mucosal defense and gut/lung function in the preterm infant

Publications (2)

Publication Number Publication Date
JP2021502363A JP2021502363A (ja) 2021-01-28
JP2021502363A5 true JP2021502363A5 (https=) 2021-12-23

Family

ID=60301879

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2020524879A Pending JP2021502363A (ja) 2017-11-10 2018-11-09 早期産児における粘膜抵抗力および腸／肺機能の成熟

Country Status (13)

Country Link
US (2) US20200316172A1 (https=)
EP (1) EP3706773A2 (https=)
JP (1) JP2021502363A (https=)
KR (1) KR20200095472A (https=)
CN (1) CN111556759A (https=)
AU (1) AU2018363783A1 (https=)
BR (1) BR112020009254A2 (https=)
CA (1) CA3082288A1 (https=)
MX (1) MX2020004863A (https=)
RU (1) RU2020115758A (https=)
SG (1) SG11202003868UA (https=)
WO (1) WO2019092201A2 (https=)
ZA (1) ZA202002992B (https=)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX2019006848A (es) * 2016-12-13 2019-10-07 Defensin Therapeutics Aps Metodos para tratar condiciones inflamatorias de los pulmones.
PL3713590T3 (pl) * 2017-11-24 2025-09-15 Defensin Therapeutics Aps Ludzka beta 2 defensyna do stosowania w zapobieganiu i leczeniu choroby przeszczep przeciwko gospodarzowi
KR102244161B1 (ko) * 2018-08-31 2021-04-26 주식회사 나이벡 다중의 질환 바이오마커의 기능 및 발현을 억제하는 펩타이드의 신규한 용도
CN114903973B (zh) * 2022-04-21 2025-08-29 上海市肺科医院 一种呼吸道粘膜免疫增强药物组合物
US20240252558A1 (en) * 2023-01-29 2024-08-01 The University Of Chicago Probiotics to rescue maternal immune activation-induced neurodevelopment deficits
KR20240150943A (ko) 2023-04-10 2024-10-17 (주)인트젠 영유아용 유산균 프로바이오틱스 조성물
CN116868958A (zh) * 2023-09-06 2023-10-13 中国人民解放军军事科学院军事医学研究院 构建缺氧导致肠道应激损伤的动物模型的方法

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US4235871A (en) 1978-02-24 1980-11-25 Papahadjopoulos Demetrios P Method of encapsulating biologically active materials in lipid vesicles
US4501728A (en) 1983-01-06 1985-02-26 Technology Unlimited, Inc. Masking of liposomes from RES recognition
US4837028A (en) 1986-12-24 1989-06-06 Liposome Technology, Inc. Liposomes with enhanced circulation time
US5223409A (en) 1988-09-02 1993-06-29 Protein Engineering Corp. Directed evolution of novel binding proteins
IL99552A0 (en) 1990-09-28 1992-08-18 Ixsys Inc Compositions containing procaryotic cells,a kit for the preparation of vectors useful for the coexpression of two or more dna sequences and methods for the use thereof
DE4343591A1 (de) 1993-12-21 1995-06-22 Evotec Biosystems Gmbh Verfahren zum evolutiven Design und Synthese funktionaler Polymere auf der Basis von Formenelementen und Formencodes
US5605793A (en) 1994-02-17 1997-02-25 Affymax Technologies N.V. Methods for in vitro recombination
CA2502324A1 (en) * 2002-10-14 2004-04-29 Lars Thim Glucagon - like peptide - 2 variants
JP2007063219A (ja) * 2005-09-01 2007-03-15 Juntendo 新生児壊死性腸炎疾患予防剤
AU2009209565B2 (en) 2008-02-01 2013-09-19 Ascendis Pharma As Prodrug comprising a self-cleavable linker
SG172709A1 (en) * 2008-07-18 2011-07-28 Novozymes Adenium Biotech As Treatment of inflammatory bowel diseases with mammal beta defensins
US20110223137A1 (en) * 2008-12-05 2011-09-15 Nestec S.A. Compositions for use in low-birth weight infants
KR101722961B1 (ko) 2009-02-11 2017-04-04 알부메딕스 에이/에스 알부민 변이체 및 접합체
JP6219277B2 (ja) * 2011-07-08 2017-10-25 ディフェンシン セラピューティクス アンパルトセルスカブＤｅｆｅｎｓｉｎ Ｔｈｅｒａｐｅｕｔｉｃｓ Ａｐｓ 炎症性腸疾患の経口治療
EA201200416A1 (ru) * 2012-03-12 2013-09-30 Аделя Сабир кызы Гаджиева Способ ранней диагностики и лечения некротического энтероколита у новорожденных
SG11201406628RA (en) * 2012-04-23 2014-11-27 Chiesi Farma Spa Method and system for the administration of a pulmonary surfactant by atomization
EP2968073B1 (en) * 2013-03-13 2017-08-16 Rush University Medical Center Delivery device for oropharyngeal administration of mother's colostrum and milk
BR112018015170A2 (pt) * 2016-01-26 2018-12-18 Defensin Therapeutics Aps métodos para tratamento de doenças, para promoção de crescimento magro, para tratamento ou normalização de uma microbiota disbiótica no intestino, para aumentar riqueza gênica da microbiota intestinal, para aumentar número de filos da microbiota intestinal, para aumentar produção de ácidos graxos de cadeia curta da microbiota intestinal/metaboloma, para aumentar número de bactérias, para diminuir número de bactérias, defensina a, defensina ss, ou um fragmento bioativo das mesmas, e, defensina a e/ou defensina ss e/ou um glp-1/análogo de glp-1.
MX2019006848A (es) * 2016-12-13 2019-10-07 Defensin Therapeutics Aps Metodos para tratar condiciones inflamatorias de los pulmones.

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