JP2021008626A5 - - Google Patents
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- Publication number
- JP2021008626A5 JP2021008626A5 JP2020162888A JP2020162888A JP2021008626A5 JP 2021008626 A5 JP2021008626 A5 JP 2021008626A5 JP 2020162888 A JP2020162888 A JP 2020162888A JP 2020162888 A JP2020162888 A JP 2020162888A JP 2021008626 A5 JP2021008626 A5 JP 2021008626A5
- Authority
- JP
- Japan
- Prior art keywords
- aliphatic polyester
- polyester copolymer
- crystalline
- cyclic monomer
- glycolide
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000000178 monomer Substances 0.000 claims description 20
- RKDVKSZUMVYZHH-UHFFFAOYSA-N 1,4-dioxane-2,5-dione Chemical compound O=C1COC(=O)CO1 RKDVKSZUMVYZHH-UHFFFAOYSA-N 0.000 claims description 18
- 229920001577 copolymer Polymers 0.000 claims description 10
- JJTUDXZGHPGLLC-UHFFFAOYSA-N lactide Chemical compound CC1OC(=O)C(C)OC1=O JJTUDXZGHPGLLC-UHFFFAOYSA-N 0.000 claims description 7
- 229920000642 polymer Polymers 0.000 claims description 3
- 229920003232 aliphatic polyester Polymers 0.000 claims 29
- 125000004122 cyclic group Chemical group 0.000 claims 19
- 239000002250 absorbent Substances 0.000 claims 15
- 230000002745 absorbent Effects 0.000 claims 15
- 239000002685 polymerization catalyst Substances 0.000 claims 11
- YFHICDDUDORKJB-UHFFFAOYSA-N trimethylene carbonate Chemical class O=C1OCCCO1 YFHICDDUDORKJB-UHFFFAOYSA-N 0.000 claims 11
- JJTUDXZGHPGLLC-IMJSIDKUSA-N 4511-42-6 Chemical compound C[C@@H]1OC(=O)[C@H](C)OC1=O JJTUDXZGHPGLLC-IMJSIDKUSA-N 0.000 claims 10
- 238000007151 ring opening polymerisation reaction Methods 0.000 claims 10
- OZJPLYNZGCXSJM-UHFFFAOYSA-N 5-valerolactone Chemical compound O=C1CCCCO1 OZJPLYNZGCXSJM-UHFFFAOYSA-N 0.000 claims 8
- GAEKPEKOJKCEMS-UHFFFAOYSA-N gamma-valerolactone Chemical compound CC1CCC(=O)O1 GAEKPEKOJKCEMS-UHFFFAOYSA-N 0.000 claims 8
- VPVXHAANQNHFSF-UHFFFAOYSA-N 1,4-dioxan-2-one Chemical class O=C1COCCO1 VPVXHAANQNHFSF-UHFFFAOYSA-N 0.000 claims 7
- PAPBSGBWRJIAAV-UHFFFAOYSA-N ε-Caprolactone Chemical class O=C1CCCCCO1 PAPBSGBWRJIAAV-UHFFFAOYSA-N 0.000 claims 7
- AOLNDUQWRUPYGE-UHFFFAOYSA-N 1,4-dioxepan-5-one Chemical class O=C1CCOCCO1 AOLNDUQWRUPYGE-UHFFFAOYSA-N 0.000 claims 5
- 229920001519 homopolymer Polymers 0.000 claims 4
- 239000003999 initiator Substances 0.000 claims 4
- VHYFNPMBLIVWCW-UHFFFAOYSA-N 4-Dimethylaminopyridine Chemical compound CN(C)C1=CC=NC=C1 VHYFNPMBLIVWCW-UHFFFAOYSA-N 0.000 claims 3
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 claims 3
- 125000003158 alcohol group Chemical group 0.000 claims 3
- 239000000835 fiber Substances 0.000 claims 3
- 229920001897 terpolymer Polymers 0.000 claims 3
- MWKFXSUHUHTGQN-UHFFFAOYSA-N 1-decanol group Chemical group C(CCCCCCCCC)O MWKFXSUHUHTGQN-UHFFFAOYSA-N 0.000 claims 2
- QOTQFLOTGBBMEX-UHFFFAOYSA-N alpha-angelica lactone Chemical compound CC1=CCC(=O)O1 QOTQFLOTGBBMEX-UHFFFAOYSA-N 0.000 claims 2
- BGLUXFNVVSVEET-UHFFFAOYSA-N beta-angelica lactone Chemical compound CC1OC(=O)C=C1 BGLUXFNVVSVEET-UHFFFAOYSA-N 0.000 claims 2
- WAIJESVQRKHMJR-UHFFFAOYSA-N dibutyltin;2-ethylhexanoic acid Chemical compound CCCC[Sn]CCCC.CCCCC(CC)C(O)=O WAIJESVQRKHMJR-UHFFFAOYSA-N 0.000 claims 2
- UQPHVQVXLPRNCX-UHFFFAOYSA-N erythrulose Chemical compound OCC(O)C(=O)CO UQPHVQVXLPRNCX-UHFFFAOYSA-N 0.000 claims 2
- MENOBBYDZHOWLE-UHFFFAOYSA-N morpholine-2,3-dione Chemical compound O=C1NCCOC1=O MENOBBYDZHOWLE-UHFFFAOYSA-N 0.000 claims 2
- KSBAEPSJVUENNK-UHFFFAOYSA-L tin(ii) 2-ethylhexanoate Chemical compound [Sn+2].CCCCC(CC)C([O-])=O.CCCCC(CC)C([O-])=O KSBAEPSJVUENNK-UHFFFAOYSA-L 0.000 claims 2
- DNIAPMSPPWPWGF-VKHMYHEASA-N (+)-propylene glycol Chemical compound C[C@H](O)CO DNIAPMSPPWPWGF-VKHMYHEASA-N 0.000 claims 1
- YPFDHNVEDLHUCE-UHFFFAOYSA-N 1,3-propanediol Substances OCCCO YPFDHNVEDLHUCE-UHFFFAOYSA-N 0.000 claims 1
- 239000005968 1-Decanol Substances 0.000 claims 1
- 229960000549 4-dimethylaminophenol Drugs 0.000 claims 1
- 241000125175 Angelica Species 0.000 claims 1
- 235000001287 Guettarda speciosa Nutrition 0.000 claims 1
- GSEJCLTVZPLZKY-UHFFFAOYSA-N Triethanolamine Chemical compound OCCN(CCO)CCO GSEJCLTVZPLZKY-UHFFFAOYSA-N 0.000 claims 1
- ZJCCRDAZUWHFQH-UHFFFAOYSA-N Trimethylolpropane Chemical compound CCC(CO)(CO)CO ZJCCRDAZUWHFQH-UHFFFAOYSA-N 0.000 claims 1
- 230000004888 barrier function Effects 0.000 claims 1
- 239000011248 coating agent Substances 0.000 claims 1
- 238000000576 coating method Methods 0.000 claims 1
- 239000000599 controlled substance Substances 0.000 claims 1
- 238000012377 drug delivery Methods 0.000 claims 1
- 239000004744 fabric Substances 0.000 claims 1
- 150000002596 lactones Chemical class 0.000 claims 1
- 229920000166 polytrimethylene carbonate Polymers 0.000 claims 1
- 229920001400 block copolymer Polymers 0.000 description 2
- 230000015572 biosynthetic process Effects 0.000 description 1
- 238000006243 chemical reaction Methods 0.000 description 1
- 229920000728 polyester Polymers 0.000 description 1
- -1 ranges from 50-60% Chemical compound 0.000 description 1
- 238000003786 synthesis reaction Methods 0.000 description 1
Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2022168963A JP7549632B2 (ja) | 2014-12-19 | 2022-10-21 | 熱安定性が改善された吸収性コポリマー |
| JP2024148586A JP2025010531A (ja) | 2014-12-19 | 2024-08-30 | 熱安定性が改善された吸収性コポリマー |
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201462094723P | 2014-12-19 | 2014-12-19 | |
| US62/094,723 | 2014-12-19 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017533270A Division JP6771467B2 (ja) | 2014-12-19 | 2015-12-18 | 熱安定性が改善された吸収性コポリマー |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022168963A Division JP7549632B2 (ja) | 2014-12-19 | 2022-10-21 | 熱安定性が改善された吸収性コポリマー |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2021008626A JP2021008626A (ja) | 2021-01-28 |
| JP2021008626A5 true JP2021008626A5 (https=) | 2021-05-06 |
| JP7165172B2 JP7165172B2 (ja) | 2022-11-02 |
Family
ID=56127878
Family Applications (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017533270A Active JP6771467B2 (ja) | 2014-12-19 | 2015-12-18 | 熱安定性が改善された吸収性コポリマー |
| JP2020162888A Active JP7165172B2 (ja) | 2014-12-19 | 2020-09-29 | 熱安定性が改善された吸収性コポリマー |
| JP2022168963A Active JP7549632B2 (ja) | 2014-12-19 | 2022-10-21 | 熱安定性が改善された吸収性コポリマー |
| JP2024148586A Pending JP2025010531A (ja) | 2014-12-19 | 2024-08-30 | 熱安定性が改善された吸収性コポリマー |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017533270A Active JP6771467B2 (ja) | 2014-12-19 | 2015-12-18 | 熱安定性が改善された吸収性コポリマー |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022168963A Active JP7549632B2 (ja) | 2014-12-19 | 2022-10-21 | 熱安定性が改善された吸収性コポリマー |
| JP2024148586A Pending JP2025010531A (ja) | 2014-12-19 | 2024-08-30 | 熱安定性が改善された吸収性コポリマー |
Country Status (4)
| Country | Link |
|---|---|
| US (3) | US20160177026A1 (https=) |
| EP (2) | EP3233963B1 (https=) |
| JP (4) | JP6771467B2 (https=) |
| WO (1) | WO2016100915A2 (https=) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2019046808A1 (en) * | 2017-09-01 | 2019-03-07 | Poly-Med, Inc. | POLYMERS FOR ADDITIVE MANUFACTURE |
| CA3096216A1 (en) | 2018-04-06 | 2019-10-10 | Poly-Med, Inc. | Methods and compositions for photopolymerizable additive manufacturing |
| US11639416B2 (en) | 2018-04-19 | 2023-05-02 | Poly-Med, Inc. | Macromers and compositions for photocuring processes |
| CN117468113A (zh) * | 2019-03-06 | 2024-01-30 | 聚合-医药有限公司 | 适用于增材制造的聚合物 |
| WO2023033730A2 (en) * | 2021-08-31 | 2023-03-09 | Agency For Science, Technology And Research | A method of producing a bioactive polymer filament, the bioactive polymer filament and printing methods using the same |
| JP7782797B2 (ja) * | 2021-10-13 | 2025-12-09 | 学校法人 関西大学 | 分岐型生分解性ポリエステル及びその利用 |
| CN115232297B (zh) * | 2022-06-30 | 2023-06-27 | 中国神华煤制油化工有限公司 | 聚乙醇酸/脂肪族聚碳酸酯三嵌段共聚物及其制备方法 |
| EP4705557A1 (en) * | 2023-04-25 | 2026-03-11 | Poly-Med Inc. | Compositions and methods for nonwoven materials |
Family Cites Families (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP3257750B2 (ja) * | 1993-07-20 | 2002-02-18 | エチコン・インコーポレーテツド | ε−カプロラクトンおよびラクチドの液状コポリマー |
| US5393841A (en) | 1993-11-09 | 1995-02-28 | Shell Oil Company | Dissimilar arm asymmetric radial or star block copolymers for adhesives and sealants |
| US5462169A (en) | 1994-09-23 | 1995-10-31 | Ring Can Corporation | Composite package for hazardous materials |
| US5633343A (en) | 1995-06-30 | 1997-05-27 | Ethicon, Inc. | High strength, fast absorbing, melt processable, gycolide-rich, poly(glycolide-co-p-dioxanone) copolymers |
| AU707772B2 (en) | 1995-11-06 | 1999-07-22 | Ethicon Inc. | Polymer blends containing polyoxaesters |
| US6342065B1 (en) | 1999-03-17 | 2002-01-29 | Poly-Med, Inc. | High strength fibers of L-lactide copolymers ε-caprolactone and trimethylene carbonate and absorbable medical constructs thereof |
| US6462169B1 (en) * | 1999-11-30 | 2002-10-08 | Poly-Med, Inc. | Amorphous polymeric polyaxial initiators and compliant crystalline copolymers therefrom |
| US6794485B2 (en) * | 2000-10-27 | 2004-09-21 | Poly-Med, Inc. | Amorphous polymeric polyaxial initiators and compliant crystalline copolymers therefrom |
| US20020161168A1 (en) * | 2000-10-27 | 2002-10-31 | Shalaby Shalaby W. | Amorphous polymeric polyaxial initiators and compliant crystalline copolymers therefrom |
| US7265186B2 (en) | 2001-01-19 | 2007-09-04 | Nektar Therapeutics Al, Corporation | Multi-arm block copolymers as drug delivery vehicles |
| US6498229B1 (en) | 2001-09-05 | 2002-12-24 | Poly-Med, Inc. | Direct synthesis of segmented glycolide copolymers and crystalline materials therefrom |
| US6794484B2 (en) | 2002-06-28 | 2004-09-21 | Ethicon, Inc. | Crystallizable polylactone copolymers prepared from mono- and di-functional polymerization initiators |
| WO2005065079A2 (en) | 2003-11-10 | 2005-07-21 | Angiotech International Ag | Medical implants and fibrosis-inducing agents |
| WO2005049105A2 (en) | 2003-11-10 | 2005-06-02 | Angiotech International Ag | Medical implants and anti-scarring agents |
| EP1761283A2 (en) | 2004-06-07 | 2007-03-14 | California Institute Of Technology | Biodegradable drug-polymer delivery system |
| US20060095122A1 (en) * | 2004-10-29 | 2006-05-04 | Advanced Cardiovascular Systems, Inc. | Implantable devices comprising biologically absorbable star polymers and methods for fabricating the same |
| US20070043434A1 (en) * | 2005-08-18 | 2007-02-22 | David Meerkin | Biodegradable endovascular stent using stereocomplexation of polymers |
| US9248094B2 (en) * | 2006-10-30 | 2016-02-02 | Poly-Med, Inc. | Suture-specific coatings for modulated release of bioactive agents |
| DE102006053752A1 (de) * | 2006-11-13 | 2008-05-15 | Aesculap Ag & Co. Kg | Textile Gefäßprothese mit Beschichtung |
| US9011439B2 (en) * | 2006-11-20 | 2015-04-21 | Poly-Med, Inc. | Selectively absorbable/biodegradable, fibrous composite constructs and applications thereof |
| US8262723B2 (en) | 2007-04-09 | 2012-09-11 | Abbott Cardiovascular Systems Inc. | Implantable medical devices fabricated from polymer blends with star-block copolymers |
| WO2010123574A1 (en) | 2009-04-23 | 2010-10-28 | Atrp Solutions Inc | Star macromolecules for personal and home care |
| US8858980B2 (en) * | 2012-04-12 | 2014-10-14 | Poly-Med, Inc. | Synthetic mechanical hemostatic composition, method of making and use thereof |
| EP3215514B1 (en) | 2014-11-03 | 2018-11-21 | F. Hoffmann-La Roche AG | Bace1 inhibitors |
-
2015
- 2015-12-18 JP JP2017533270A patent/JP6771467B2/ja active Active
- 2015-12-18 WO PCT/US2015/066869 patent/WO2016100915A2/en not_active Ceased
- 2015-12-18 EP EP15871232.3A patent/EP3233963B1/en active Active
- 2015-12-18 US US14/975,303 patent/US20160177026A1/en not_active Abandoned
- 2015-12-18 EP EP25200472.6A patent/EP4696733A3/en active Pending
-
2019
- 2019-08-08 US US16/536,093 patent/US12398236B2/en active Active
-
2020
- 2020-09-29 JP JP2020162888A patent/JP7165172B2/ja active Active
-
2022
- 2022-10-21 JP JP2022168963A patent/JP7549632B2/ja active Active
-
2024
- 2024-08-30 JP JP2024148586A patent/JP2025010531A/ja active Pending
-
2025
- 2025-07-22 US US19/276,452 patent/US20250346712A1/en active Pending
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