JP2020532513A - トリアミノピリミジン化合物およびその中間体の調製方法 - Google Patents
トリアミノピリミジン化合物およびその中間体の調製方法 Download PDFInfo
- Publication number
- JP2020532513A JP2020532513A JP2020511759A JP2020511759A JP2020532513A JP 2020532513 A JP2020532513 A JP 2020532513A JP 2020511759 A JP2020511759 A JP 2020511759A JP 2020511759 A JP2020511759 A JP 2020511759A JP 2020532513 A JP2020532513 A JP 2020532513A
- Authority
- JP
- Japan
- Prior art keywords
- compound
- triaminopyrimidine
- solvents
- acid
- dimethyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
- A61P33/06—Antimalarials
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/72—Nitrogen atoms
- C07D213/73—Unsubstituted amino or imino radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/13—Crystalline forms, e.g. polymorphs
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Tropical Medicine & Parasitology (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IN201721031453 | 2017-09-05 | ||
| IN201721031453 | 2017-09-05 | ||
| IN201721034342 | 2017-09-27 | ||
| IN201721034342 | 2017-09-27 | ||
| PCT/IB2018/056732 WO2019049021A1 (en) | 2017-09-05 | 2018-09-04 | PROCESS FOR THE PREPARATION OF TRIAMINOPYRIMIDINE COMPOUND AND ITS INTERMEDIATES |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2020532513A true JP2020532513A (ja) | 2020-11-12 |
| JP2020532513A5 JP2020532513A5 (enExample) | 2021-09-30 |
Family
ID=63684213
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020511759A Withdrawn JP2020532513A (ja) | 2017-09-05 | 2018-09-04 | トリアミノピリミジン化合物およびその中間体の調製方法 |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US12378223B2 (enExample) |
| EP (1) | EP3679030B1 (enExample) |
| JP (1) | JP2020532513A (enExample) |
| CN (1) | CN111051299A (enExample) |
| CA (1) | CA3071226A1 (enExample) |
| ES (1) | ES2979379T3 (enExample) |
| MX (2) | MX2020002142A (enExample) |
| PH (1) | PH12020500385A1 (enExample) |
| WO (1) | WO2019049021A1 (enExample) |
| ZA (1) | ZA202000903B (enExample) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2025115034A1 (en) * | 2023-11-30 | 2025-06-05 | Zydus Lifesciences Limited | A process for the preparation of a triaminopyrimidine compound and novel intermediates thereof |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RS58124B1 (sr) * | 2014-04-28 | 2019-02-28 | Medicines For Malaria Venture Mmv | Triaminopirimidin jedinjenja korisna za prevenciju ili tretman malarije |
-
2018
- 2018-09-04 EP EP18778565.4A patent/EP3679030B1/en active Active
- 2018-09-04 US US16/640,491 patent/US12378223B2/en active Active
- 2018-09-04 JP JP2020511759A patent/JP2020532513A/ja not_active Withdrawn
- 2018-09-04 CN CN201880055980.1A patent/CN111051299A/zh active Pending
- 2018-09-04 MX MX2020002142A patent/MX2020002142A/es unknown
- 2018-09-04 ES ES18778565T patent/ES2979379T3/es active Active
- 2018-09-04 CA CA3071226A patent/CA3071226A1/en active Pending
- 2018-09-04 WO PCT/IB2018/056732 patent/WO2019049021A1/en not_active Ceased
-
2020
- 2020-02-12 ZA ZA2020/00903A patent/ZA202000903B/en unknown
- 2020-02-25 MX MX2024002113A patent/MX2024002113A/es unknown
- 2020-02-27 PH PH12020500385A patent/PH12020500385A1/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| ZA202000903B (en) | 2024-07-31 |
| EP3679030B1 (en) | 2024-03-27 |
| US12378223B2 (en) | 2025-08-05 |
| EP3679030A1 (en) | 2020-07-15 |
| MX2024002113A (es) | 2024-03-06 |
| PH12020500385A1 (en) | 2020-12-07 |
| CN111051299A (zh) | 2020-04-21 |
| US20200207738A1 (en) | 2020-07-02 |
| CA3071226A1 (en) | 2019-03-14 |
| BR112020003557A2 (pt) | 2020-09-01 |
| WO2019049021A1 (en) | 2019-03-14 |
| ES2979379T3 (es) | 2024-09-25 |
| MX2020002142A (es) | 2020-07-20 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20210818 |
|
| A621 | Written request for application examination |
Free format text: JAPANESE INTERMEDIATE CODE: A621 Effective date: 20210818 |
|
| A761 | Written withdrawal of application |
Free format text: JAPANESE INTERMEDIATE CODE: A761 Effective date: 20220516 |
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| A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A821 Effective date: 20220517 |