JP2020528758A5 - - Google Patents
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- JP2020528758A5 JP2020528758A5 JP2020505231A JP2020505231A JP2020528758A5 JP 2020528758 A5 JP2020528758 A5 JP 2020528758A5 JP 2020505231 A JP2020505231 A JP 2020505231A JP 2020505231 A JP2020505231 A JP 2020505231A JP 2020528758 A5 JP2020528758 A5 JP 2020528758A5
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- 229920001184 polypeptide Polymers 0.000 claims 43
- 102000004196 processed proteins & peptides Human genes 0.000 claims 43
- 108090000765 processed proteins & peptides Proteins 0.000 claims 43
- 239000012634 fragment Substances 0.000 claims 30
- 239000000427 antigen Substances 0.000 claims 25
- 102000036639 antigens Human genes 0.000 claims 25
- 108091007433 antigens Proteins 0.000 claims 25
- 239000003446 ligand Substances 0.000 claims 8
- -1 ICOS Proteins 0.000 claims 7
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- 101000764263 Homo sapiens Tumor necrosis factor ligand superfamily member 4 Proteins 0.000 claims 1
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- 102100026720 Interferon beta Human genes 0.000 claims 1
- 102100026688 Interferon epsilon Human genes 0.000 claims 1
- 101710147309 Interferon epsilon Proteins 0.000 claims 1
- 102100037850 Interferon gamma Human genes 0.000 claims 1
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- 101710145151 Interferon lambda receptor 1 Proteins 0.000 claims 1
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- 108010047761 Interferon-alpha Proteins 0.000 claims 1
- 102000006992 Interferon-alpha Human genes 0.000 claims 1
- 108090000467 Interferon-beta Proteins 0.000 claims 1
- 102000008070 Interferon-gamma Human genes 0.000 claims 1
- 108010002352 Interleukin-1 Proteins 0.000 claims 1
- 102000000589 Interleukin-1 Human genes 0.000 claims 1
- 108090000174 Interleukin-10 Proteins 0.000 claims 1
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- 102000004211 Platelet factor 4 Human genes 0.000 claims 1
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- 108010065158 Tumor Necrosis Factor Ligand Superfamily Member 14 Proteins 0.000 claims 1
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- FOCAHLGSDWHSAH-UHFFFAOYSA-N difluoromethanethione Chemical compound FC(F)=S FOCAHLGSDWHSAH-UHFFFAOYSA-N 0.000 claims 1
- 229940079593 drug Drugs 0.000 claims 1
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Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2023097920A JP2023123588A (ja) | 2017-07-31 | 2023-06-14 | 可変ドメインと定常ドメインとの間のエルボー領域に機能的ドメインを有する抗体 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EPPCT/EP2017/069357 | 2017-07-31 | ||
| PCT/EP2017/069357 WO2019024979A1 (en) | 2017-07-31 | 2017-07-31 | FUNCTIONAL DOMAIN ANTIBODIES IN THE ELBOW REGION |
| PCT/EP2018/070640 WO2019025391A1 (en) | 2017-07-31 | 2018-07-30 | ANTIBODIES HAVING FUNCTIONAL DOMAINS IN THE ELBOW REGION BETWEEN A VARIABLE DOMAIN AND A CONSTANT DOMAIN |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023097920A Division JP2023123588A (ja) | 2017-07-31 | 2023-06-14 | 可変ドメインと定常ドメインとの間のエルボー領域に機能的ドメインを有する抗体 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2020528758A JP2020528758A (ja) | 2020-10-01 |
| JP2020528758A5 true JP2020528758A5 (https=) | 2021-09-09 |
| JP7297734B2 JP7297734B2 (ja) | 2023-06-26 |
Family
ID=59626578
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020505231A Active JP7297734B2 (ja) | 2017-07-31 | 2018-07-30 | 可変ドメインと定常ドメインとの間のエルボー領域に機能的ドメインを有する抗体 |
| JP2023097920A Withdrawn JP2023123588A (ja) | 2017-07-31 | 2023-06-14 | 可変ドメインと定常ドメインとの間のエルボー領域に機能的ドメインを有する抗体 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023097920A Withdrawn JP2023123588A (ja) | 2017-07-31 | 2023-06-14 | 可変ドメインと定常ドメインとの間のエルボー領域に機能的ドメインを有する抗体 |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US12331108B2 (https=) |
| EP (1) | EP3661962A1 (https=) |
| JP (2) | JP7297734B2 (https=) |
| KR (1) | KR20200032738A (https=) |
| CN (1) | CN111094341A (https=) |
| AU (1) | AU2018311032B2 (https=) |
| BR (1) | BR112019028180A2 (https=) |
| CA (1) | CA3069265A1 (https=) |
| EA (1) | EA202090364A1 (https=) |
| IL (1) | IL272303A (https=) |
| MX (1) | MX2020001080A (https=) |
| SG (1) | SG11201911658QA (https=) |
| WO (2) | WO2019024979A1 (https=) |
Families Citing this family (43)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CA3066918A1 (en) | 2017-06-12 | 2018-12-20 | Bluefin Biomedicine, Inc. | Anti-il1rap antibodies and antibody drug conjugates |
| CN120463807A (zh) | 2018-03-22 | 2025-08-12 | 表面肿瘤学有限责任公司 | 抗il-27抗体及其用途 |
| JP7384415B2 (ja) * | 2018-05-10 | 2023-11-21 | ミラバイオロジクス株式会社 | 抗体の抗原結合領域を含み、生理活性ペプチドを融合する人工タンパク質 |
| KR20210016446A (ko) | 2018-05-30 | 2021-02-15 | 인스티튜트 포 리서치 인 바이오메드슨 | 내인성 활성화-유도 시티딘 탈아미노효소를 이용한 b 림프구의 조작 |
| US12006345B2 (en) | 2019-02-21 | 2024-06-11 | Xencor, Inc. | Untargeted and targeted IL-10 Fc-fusion proteins |
| JP2023512684A (ja) | 2020-02-03 | 2023-03-28 | ヴィア・バイオテクノロジー・インコーポレイテッド | Ｓａｒｓ－ｃｏｖ－２に対する抗体およびそれを使用する方法 |
| SG11202110145SA (en) | 2020-02-26 | 2021-10-28 | Vir Biotechnology Inc | Antibodies against sars-cov-2 and methods of using the same |
| WO2021203053A1 (en) | 2020-04-03 | 2021-10-07 | Vir Biotechnology, Inc. | Immunotherapy targeting a conserved region in sars coronaviruses |
| JP2023523549A (ja) | 2020-04-14 | 2023-06-06 | ヴィア・バイオテクノロジー・インコーポレイテッド | ＳＡＲＳ－ＣｏＶ－２に対する抗体およびそれを使用する方法 |
| MX2022013886A (es) | 2020-05-08 | 2022-11-30 | Vir Biotechnology Inc | Anticuerpos contra coronavirus de tipo 2 causante del sindrome respiratorio agudo severo (sars-cov-2). |
| WO2021247925A1 (en) | 2020-06-03 | 2021-12-09 | Vir Biotechnology, Inc. | Structure-guided immunotherapy against sars-cov-2 |
| TW202207983A (zh) | 2020-06-12 | 2022-03-01 | 美商維爾生物科技股份有限公司 | 用於sars-cov-2感染的抗體療法 |
| BR112023005684A2 (pt) | 2020-09-28 | 2023-11-07 | Humabs Biomed Sa | Anticorpos contra sars-cov-2 |
| CN113307870B (zh) * | 2020-10-30 | 2022-12-23 | 上海洛启生物医药技术有限公司 | 抗il5纳米抗体及其应用 |
| JP2023551666A (ja) | 2020-11-23 | 2023-12-12 | ヴィア・バイオテクノロジー・インコーポレイテッド | Ａ型インフルエンザウイルスに対する抗体 |
| TW202235105A (zh) | 2020-11-23 | 2022-09-16 | 美商維爾生物科技股份有限公司 | 抗流感抗體及其組合 |
| JP2023551668A (ja) | 2020-11-23 | 2023-12-12 | ヴィア・バイオテクノロジー・インコーポレイテッド | インフルエンザのノイラミニダーゼに対する広域中和抗体 |
| EP4251279A1 (en) | 2020-11-25 | 2023-10-04 | VIR Biotechnology, Inc. | Antibodies that bind to multiple betacoronaviruses |
| AR124414A1 (es) * | 2020-12-18 | 2023-03-22 | Century Therapeutics Inc | Sistema de receptor de antígeno quimérico con especificidad de receptor adaptable |
| KR20230126718A (ko) * | 2020-12-30 | 2023-08-30 | 우시 바이올로직스 아일랜드 리미티드 | 다중특이적 항원 결합 단백질 |
| CN112877394A (zh) * | 2021-01-27 | 2021-06-01 | 南京大学 | B7-h4+单核细胞型mdsc在制备ins激素治疗疗效预测试剂中的应用 |
| CN117136197A (zh) * | 2021-02-09 | 2023-11-28 | 胡默波斯生物医学公司 | 抗呼吸道合胞病毒、人偏肺病毒和小鼠肺炎病毒的抗体和其使用方法 |
| WO2022204202A1 (en) | 2021-03-23 | 2022-09-29 | Vir Biotechnology, Inc. | Antibodies that bind to multiple sarbecoviruses |
| KR20240004680A (ko) * | 2021-05-07 | 2024-01-11 | 센티 바이오사이언시스, 인코포레이티드 | 키메라 수용체 및 이의 사용 방법 |
| CA3218489A1 (en) | 2021-05-24 | 2022-12-01 | Vir Biotechnology, Inc. | Engineered polypeptides |
| WO2023034871A1 (en) | 2021-09-01 | 2023-03-09 | Vir Biotechnology, Inc. | High concentration antibody therapies for sars-cov-2 infection |
| US20240400652A1 (en) | 2021-09-01 | 2024-12-05 | Vir Biotechnology, Inc. | Antibody therapies for sars-cov-2 infection in pediatric subjects |
| CN114934065A (zh) * | 2021-11-25 | 2022-08-23 | 浙江理工大学绍兴生物医药研究院有限公司 | 携带免疫检查点分子tim-3抗体基因的溶瘤腺病毒构建方法和应用 |
| WO2023108028A2 (en) | 2021-12-10 | 2023-06-15 | Omeros Corporation | Therapeutic antibodies that bind to the serine protease domain of masp-2 and uses thereof |
| EP4489782A4 (en) | 2022-03-10 | 2026-03-25 | Omeros Corp | MASP-2 and MASP-3 inhibitors, and associated compositions and methods for the treatment of sickle cell disease |
| WO2023201256A1 (en) | 2022-04-12 | 2023-10-19 | Vir Biotechnology, Inc. | High dose antibody therapies for sars-cov-2 infection |
| WO2023230448A1 (en) | 2022-05-23 | 2023-11-30 | Vir Biotechnology, Inc. | Combination immunotherapy for influenza |
| CA3256285A1 (en) | 2022-05-23 | 2023-11-30 | Humabs Biomed Sa | Broadly neutralizing antibodies directed against influenza neuraminidase |
| WO2023245078A1 (en) | 2022-06-15 | 2023-12-21 | Humabs Biomed Sa | Anti-parvovirus antibodies and uses thereof |
| WO2024006472A1 (en) | 2022-06-30 | 2024-01-04 | Vir Biotechnology, Inc. | Antibodies that bind to multiple sarbecoviruses |
| US20260028391A1 (en) | 2022-07-27 | 2026-01-29 | Humabs Biomed Sa | Broadly neutralizing antibodies against rsv and mpv paramyxoviruses |
| WO2024112818A1 (en) | 2022-11-22 | 2024-05-30 | Humabs Biomed Sa | Engineered anti-sars-cov-2 antibodies and uses thereof |
| WO2024118998A2 (en) | 2022-12-01 | 2024-06-06 | Vir Biotechnology, Inc. | Engineered anti-sars-cov-2 antibodies and methods of using the same |
| EP4695286A1 (en) | 2023-04-10 | 2026-02-18 | VIR Biotechnology, Inc. | Antibodies that bind to multiple sarbecoviruses |
| WO2025010424A1 (en) | 2023-07-06 | 2025-01-09 | Vir Biotechnology, Inc. | Antibodies against staphylococcus antigens and methods of using the same |
| WO2025015321A1 (en) | 2023-07-13 | 2025-01-16 | Vir Biotechnology, Inc. | Broadly neutralizing antibodies against rsv and mpv paramyxoviruses |
| WO2026039642A1 (en) | 2024-08-16 | 2026-02-19 | Ardeagen Corporation | Anti-mesothelin antibody conjugates and methods of use thereof |
| WO2026055183A1 (en) | 2024-09-03 | 2026-03-12 | Vir Biotechnology, Inc | Antiviral compositions and methods of using the same |
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| CA2410551A1 (en) * | 2000-06-30 | 2002-01-10 | Vlaams Interuniversitair Instituut Voor Biotechnologie Vzw (Vib) | Heterodimeric fusion proteins |
| WO2004076677A2 (en) | 2003-02-26 | 2004-09-10 | Institute For Research In Biomedicine | Monoclonal antibody production by ebv transformation of b cells |
| CA2529945A1 (en) | 2003-06-27 | 2005-01-06 | Biogen Idec Ma Inc. | Use of hydrophobic-interaction-chromatography or hinge-region modifications for the production of homogeneous antibody-solutions |
| MX2009012343A (es) | 2007-05-14 | 2010-02-10 | Biogen Idec Inc | Regiones fc (sc fc) de cadena sencilla, polipeptidos de enlace que comprenden las mismas, y metodos relacionados con ello. |
| KR20100058509A (ko) * | 2007-07-31 | 2010-06-03 | 메디뮨 엘엘씨 | 다중특이적 에피토프 결합 단백질 및 이의 용도 |
| BRPI0914092B1 (pt) | 2008-10-22 | 2021-08-31 | Institute For Research In Biomedicine | Método de produção de um anticorpo a partir de células plasmáticas, método de produção de um anticorpo monoclonal a partir de células plasmáticas e método de produção de um anticorpo ou de um fragmento de anticorpo |
| WO2012088290A2 (en) | 2010-12-22 | 2012-06-28 | Abbott Laboratories | Tri-variable domain binding proteins and uses thereof |
| EP2938637A2 (en) * | 2012-12-28 | 2015-11-04 | AbbVie Inc. | Multivalent binding protein compositions |
| US20140235476A1 (en) * | 2012-12-28 | 2014-08-21 | Abbvie, Inc. | Multivalent binding protein compositions and methods for identifying variants of same |
| JP6262768B2 (ja) | 2013-01-03 | 2018-01-17 | セルトリオン， インク． | 抗体−リンカー−薬物結合体、その製造方法およびそれを含む抗癌剤組成物 |
| EP3288975A1 (en) * | 2015-04-29 | 2018-03-07 | Institute for Research in Biomedicine | Ultra-potent neutralization of cytokines by multispecific antibodies and uses thereof |
| CA2989378A1 (en) * | 2015-06-18 | 2016-12-22 | Vib Vzw | Immunoglobulin single variable domain antibody against rsv prefusion f protein |
| TWI769982B (zh) | 2015-06-24 | 2022-07-11 | 日商Ｊｃｒ製藥股份有限公司 | 通過血腦障壁之抗人類運鐵蛋白受體抗體 |
| EP3313871A1 (en) | 2015-06-26 | 2018-05-02 | Institute for Research in Biomedicine | Proteins comprising a mutated lair-1 fragment and uses thereof |
| JP7058219B2 (ja) | 2015-12-07 | 2022-04-21 | ゼンコア インコーポレイテッド | Ｃｄ３及びｐｓｍａに結合するヘテロ二量体抗体 |
| JP7384415B2 (ja) * | 2018-05-10 | 2023-11-21 | ミラバイオロジクス株式会社 | 抗体の抗原結合領域を含み、生理活性ペプチドを融合する人工タンパク質 |
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2018
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- 2018-07-30 WO PCT/EP2018/070640 patent/WO2019025391A1/en not_active Ceased
- 2018-07-30 CN CN201880048796.4A patent/CN111094341A/zh active Pending
- 2018-07-30 JP JP2020505231A patent/JP7297734B2/ja active Active
- 2018-07-30 EP EP18752697.5A patent/EP3661962A1/en active Pending
- 2018-07-30 AU AU2018311032A patent/AU2018311032B2/en active Active
- 2018-07-30 BR BR112019028180-0A patent/BR112019028180A2/pt not_active Application Discontinuation
- 2018-07-30 MX MX2020001080A patent/MX2020001080A/es unknown
- 2018-07-30 SG SG11201911658QA patent/SG11201911658QA/en unknown
- 2018-07-30 KR KR1020207006050A patent/KR20200032738A/ko active Pending
- 2018-07-30 US US16/635,506 patent/US12331108B2/en active Active
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2020
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