JP2020527083A - Assisted injection device for reducing labor and injecting compositions contained within medical containers - Google Patents

Abstract

The present invention is an assistive injection device (1) for injecting a composition contained in a medical container (40), which is a −body (10) and a medical container (40) as a body (10). A body (10) and a-spring-loaded piston rod (30) that are adapted to accept in a fixed position relative to) and are configured to be held by the user's hand. 10) Inside, the proximal stationary position and the distal operating position where the piston rod (30) engages the stopper (44) of the medical container (40) and pushes the stopper (44) into the medical container (40). A blocking system comprising a spring-loaded piston rod that can be translated between them and locking members (50, 60, 70) configured to engage the-piston rods. , The locking member holds the piston rod (30) in the proximal stationary position, and the locking member moves the piston rod (30) from the proximal stationary position to the distal operating position under the force of the spring (31). A piston rod (30) is a proximal end (32) that extends out of the body (10) and is locked, with a blocking system that is movable to and from an open position that allows it to. Proximal end configured to accelerate the movement of the piston rod (30) to the distal operating position by being pushed distally by the user when the member (50, 60, 70) is in the open position. With respect to assistive injection devices, including.

Description

The present invention relates to an assisted injection device for injecting a composition contained in a medical container. The injection device makes injection of the composition easier for users who need to reduce the effort to inject the composition, especially if the composition has a high viscosity, and the injection flow rate during the injection. To control.

Prefilled injection devices are common containers for delivering drugs or vaccines to patients, including syringes, cartridges, and automatic injectors. They usually include a sealing stopper that slides into the container and the container is filled with a pharmaceutical composition, thereby providing the practitioner with an injection device ready for use by the patient.

The container has a substantially cylindrical shape and has a proximal end that can be sealed by a sealing stopper, a distal end from which the pharmaceutical composition is discharged from the container, and a proximal and distal ends of the container. It has a peripheral wall that extends between them. In fact, the sealing stopper is intended to slide from the proximal end of the container body towards the distal end of the container body when pressure is applied by the piston rod, thereby containing the drug contained in the container body. To discharge.

The use of a pre-filled injection device leads to several advantages compared to an empty injection device that is filled with a vial-stored pharmaceutical composition just prior to injection into the patient's body. In particular, by limiting pre-injection preparation, pre-filled injection devices reduce medical medication errors, minimize the risk of pathogen contamination, and enhance practitioner convenience. In addition, such pre-filled containers can facilitate and simplify patient self-administration, which can reduce treatment costs and increase patient adherence. .. Finally, the prefilled injection device reduces the loss of valuable pharmaceutical composition that normally occurs when the pharmaceutical composition is transferred from the vial to the non-prefilled injection device. As a result, the number of possible injections per given production batch of pharmaceutical composition is increased, thus reducing purchase and supply chain costs.

In certain cases, injection of a pharmaceutical composition contained in a container by a manual injection device such as a syringe can be difficult due to the force that must be applied onto the piston rod to eject the composition. This is, for example, if the pharmaceutical composition has a high viscosity and / or suffers from any type of disease affecting, for example, rheumatoid arthritis or the user's hands or fingers, pressing the piston rod strongly with the fingers. Occurs when the injection is done manually by a user who cannot. The injection may be self-administered or may be given to another person by a user such as a health care professional. When a health care professional gives a patient repeated injections of a viscous drug, repeating the same posture that requires a large amount of force on the plunger rod to make the injection can cause repetitive strain injury.

The automatic syringe can assist the user in performing an automatic injection of the pharmaceutical composition. These usually include an injection button that the user must press to initiate an injection.

However, the user cannot change the injection flow rate (or injection rate) while performing the injection with the automatic syringe. In other words, it is not possible to increase or decrease the injection flow rate while performing the injection.

Such a lack of control of the injection flow rate can cause pain and anxiety for the user, which can lead to the user not being able to perform the injection correctly.

Moreover, like manual injection devices, automatic syringes may encounter difficulties in injecting highly viscous pharmaceutical compositions, primarily due to insufficient force exerted on the piston by the injection mechanism. Therefore, the pharmaceutical composition is not ejected from the container, or if possible, at a very slow rate.

In view of the above, an injection device for injecting a pharmaceutical composition contained in a medical container, particularly when the pharmaceutical composition has a high viscosity and / or when the user's physical strength is reduced. There is a strong need for injection devices that allow injection of compositions that are easier than existing injection devices. There is also a need for injection devices that allow the user to control the injection, especially to adjust the injection flow rate while performing the injection.

Therefore, an object of the present invention is to provide an assisted injection device for injecting a pharmaceutical composition contained in a medical container, which overcomes the drawbacks of known devices.

One object of the present invention is an assistive injection device for injecting a composition contained in a medical container.
-The body and the body, which is adapted to accept the medical container in a fixed position with respect to the body and is configured to be held by the user's hand.
-A spring-loaded piston rod that translates between the proximal stationary position inside the body and the distal operating position where the piston rod engages the stopper of the medical container and pushes the stopper into the medical container. Movable, spring-loaded piston rods,
-A blocking system with a locking member configured to engage the piston rod, the locking member being in a locking position where the locking member holds the piston rod in a proximal stationary position and where the locking member is a spring force. Equipped with a blocking system that is movable to and from an open position that allows the piston rod to be moved from the proximal rest position to the distal operating position underneath.
The piston rod is a proximal end that extends out of the body so that when the locking member is in the unlocked position, it is pushed distally by the user to accelerate the movement of the piston rod to the distal operating position. An assisted injection device that comprises a proximal end.

In the present application, "distal direction" is understood to mean the direction of injection into the medical container in which the device of the invention is mounted. The distal direction corresponds to the direction of travel of the piston rod during injection, and the medical composition initially contained within the medical container is expelled from the medical container. "Proximal direction" shall be understood to mean the opposite direction of the injection.

According to other optional features of the device of the invention:
-Proximal stationary position of the piston rod allows the medical container to be inserted into the body,
-The locking member is mounted on the body, in the locked position the locking member works with the body to hold the piston rod in the proximal stationary position, and in the released position the locking member works with the body. Allows the piston rod to move from the proximal stationary position to the distal operating position under the force of the spring,
-The piston rod is provided with a transverse hole and the locking member is radially inserted into the transverse hole of the piston rod when in the locked position and removed from the transverse hole when in the open position. And
-The insert is slidable on the proximal wall of the body, opposite the medical container,
-The proximal wall of the body features a notch adapted to slidably receive the insert inside, the notch extending radially to the piston rod and when the piston rod is in the proximal resting position. Aligned with the hole in the piston rod,
-The peripheral wall of the body of the device is provided with a transverse opening that forms a transverse passage through the body, and when in the locked position, the insert is radially inserted into the transverse opening of the body. When crossing the hole in the piston rod aligned with the opening and in the open position, the insert is removed from the transverse opening.
-The peripheral wall of the body of the device is provided with a transverse opening that forms a transverse passage through the body, and when in the locked position, the insert is radially in the transverse opening of the body with a piston rod. Inserted distally from, thereby the piston rod abuts the insert and when in the open position the insert is removed from the transverse through hole.
-The piston rod is provided with a narrowed section, the locking member is a latch provided with at least a first hole and a second hole communicating with each other, the diameter of the first hole being that of the piston rod. Smaller than the diameter, the diameter of the second hole is larger than the diameter of the piston rod, the latch has a locking position where the first hole is aligned with the piston rod and accommodates the narrowed section of the piston rod, and the first The hole 2 is aligned with the piston rod and is radially slidable with the release position crossed by the piston rod.
-The latch is slidable on the proximal wall of the body, opposite the medical container (40).
-The piston rod is provided with a toothed rack, the blocking system is mounted on the body of the device, with buttons coupled to the locking member, which is the wing, and the wing is on a structure fixed to the body. Mounted pivotally, the wing is in a locked position where the button is released and the wing engages the toothed rack to block the piston rod, and the button is pressed and the wing disengages from the toothed rack. It is pivotally movable to and from the release position that allows the piston rod to move,
-The button is advantageously a spring loaded button,
-The body is a container holder system that is configured to receive at least a portion of the medical container, with the piston rod engaging the medical container stopper as it moves from the proximal rest position to the distal operating position. Equipped with a container holder system configured to align and hold the medical container in the direction of movement of the piston rod, much like pushing a stopper into a medical container to inject the composition.
-Container holder system:
-A slot provided in the perimeter wall of the body that connects to a housing configured to receive at least a portion of the medical container and keep the medical container in a fixed position aligned with the direction of movement of the piston rod.
-A through groove provided within the distal wall of the body, continuous with the slot, extending into the distal wall from the slot, the groove to guide the medical container inserted into the housing through the slot. It is provided with a through groove configured in.

Another object of the present invention is an assisted injection device assembly, the assisted injection device assembly comprising the assisted injection device as described above and a medical container mounted on the assisted injection device. ..

The assisted injection device assembly comprises, optionally, a spacer configured to be secured to the stopper, which is contacted by the piston rod as it moves from the proximal rest position to the distal operating position. And is configured to be pushed with the stopper.

Further features and advantages of the present invention will become apparent from the detailed description that follows with reference to the accompanying figures.
FIG. 5 is an overall perspective view of an embodiment of the injection device of the present invention according to the first embodiment of the blocking system. It is an exploded perspective view of the injection device shown in FIG. FIG. 6 is a side sectional view of the device in which the blocking system blocks the piston rod in a proximal stationary position. FIG. 6 is a side sectional view of the device in which the blocking system is released and the piston rod is moved to the operating position. FIG. 5 is a side sectional view of the device at the end of injection. FIG. 5 is a cross-sectional perspective view of the device according to an alternative to the first embodiment of the blocking system. FIG. 5 is a cross-sectional perspective view of the device according to a second embodiment of the blocking system. FIG. 3 is an exploded perspective view of the device according to a third embodiment of the blocking system. FIG. 7 is a perspective view of the device shown in FIG. 7 in which the blocking system blocks the piston rod in a proximal stationary position. FIG. 7 is a cross-sectional view of the device shown in FIG. 7 in which the blocking system blocks the piston rod in a proximal stationary position. FIG. 7 is a cross-sectional view of the device shown in FIG. 7 in which the blocking system is released and the piston rod is moved to the operating position. FIG. 6 is a perspective view of the device according to a fourth embodiment of the blocking system, wherein the blocking system blocks the piston rod in a proximal stationary position. It is a side sectional view of the device shown in FIG. It is a perspective view of the device by embodiment of a container holder system. It is a side sectional view of the device shown in FIG.

The present invention proposes an assisted injection device for injecting a composition contained in a medical container.

Prior to injection, the medical container 40 is filled with a composition intended to be injected and sealed by a stopper 44 inserted therein. The sealed medical container 40 can then be mounted on the device to form an injection device assembly and inject the composition.

Referring to FIGS. 1 and 2, the injection device 1 comprises a body 10 extending along a longitudinal axis (A). The body 10 comprises a peripheral wall 11 including a grip surface 12 limited proximally and distally by a first flange 13 and a second flange 14 extending radially outward from the longitudinal axis (A), respectively. .. Therefore, when moving or using the device, the user can easily grab the body between the flanges 13 and 14. The palm of the user's hand is in contact with the grip surface 12, and the upper and lower ends of the user's hand are in contact with the flanges 13 and 14, thereby stabilizing the execution of the device. Alternatively, the user can hold the grip surface 12 between the index and middle fingers with either finger in contact with the flange 13 as if holding a standard syringe normally. The device is therefore handheld and the dimensions and weight of the device are advantageously adapted for this purpose.

The medical container 40 includes a body 46 that includes a proximal end 41 and a distal end 42 and a distal end from which the needle 43 extends. The needle 43 is covered by a cap (not exposed) to prevent any injury when handled prior to use.

The main body 10 includes a container holder system 20.

According to the embodiment shown in FIG. 1, the container holder system 20 is preferably in a second peripheral wall 11 of the body leading to a housing 22 adapted to receive the proximal end 41 of the medical container 40. Includes a slot 21 provided within the flange 14.

The container holder system 20 is provided within the distal wall 16 of the body and further includes a through groove 23 that is continuous with the slot 21 and extends into the distal wall from the slot. In a practical method, the proximal end of the medical container 40 is inserted through the slot 21 and has a diameter along the groove 23 until the container 40 is in a fixed position in the housing 22 with respect to the body 10. Moved in the direction. The groove separates the two protrusions 24 so that the proximal end 41 of the medical container 40 abuts against the protrusions, thereby preventing the medical container 40 from falling from the device.

To achieve this goal, the inner surface of the groove 23 comes into contact with the body of the container 40. In particular, the groove 23 can be configured to prevent the container 40 inserted therein from moving in the radial direction unless the container is moved by the user. Grooves, for example, rigid plastic or metal (aluminum, stainless steel) to facilitate the insertion of the container into it and to help keep the container in a fixed position within the housing 22 during injection. ) And other rigid and slippery materials.

The structure of both the slot 21 and the groove 23 can be adapted according to the type of container 40 intended to be sealed by device 1.

This embodiment is particularly useful when the medical container 40 is a syringe or the like because the proximal end 41 of the container 40 is a flange that comes into contact with the protrusion 24.

Alternatively, if the container 40 is a cylinder or the like (without a proximal flange), the configuration of the container holder system 20 may be adapted accordingly. According to the embodiments shown in FIGS. 12 and 13, the dimensions of the slot 21 and the housing 22 are adapted to accommodate the entire body 46 of the medical container 40 inserted therein, and the tip 42 of the container 40 is medical. The container 40 is moved radially along the groove 23 until it is positioned in the housing 22 where it is maintained in a fixed position with respect to the body 10. When the container 40 is positioned within the housing 22, the shoulder 47 (between the body 46 and the tip 42) comes into contact with the protrusion 24, thereby preventing the medical container 40 from falling out of the device 1. Advantageously, in this situation, only the tip 42 of the medical container 40 and the needle 43 project distally from the body 10 of the device. Of course, this embodiment can also be suitable if the medical container 40 is a syringe or the like, and the housing 22 is adapted accordingly to accommodate the flange of the medical container.

Of course, other embodiments of the container holder system are possible without departing from the scope of the present invention. For example, the medical container 40 can be longitudinally inserted through an opening provided in the distal wall of the body 10 and radially inserted into a slot provided in the peripheral wall 11 of the body 10. It can be fixed by the insert.

The device 1 includes a piston rod 30 extending in the internal volume portion 17 of the main body 10 along the shaft A. The spring 31 is arranged in the internal volume portion 17 in coaxial contact with the piston rod 30. In this way, the spring-loaded piston rod 30 is located inside the main body 10 along the axis (A) under the force of the spring 31 at a proximal stationary position, and the piston rod 30 is a stopper of the medical container 40. It engages with 44 and can be translated in translation with the distal operating position that pushes this stopper into the medical container.

With reference to FIGS. 2 and 3, the piston rod 30 advantageously comprises a radially enlarged proximal end 32 which allows the user to thumb the piston rod 30 distally. Proximal piston rod 30 by grabbing a radially enlarged proximal end 32 as an indentation surface that allows for indentation and for the user to perform another injection, eg, with another container. It acts as a handle that allows it to be pulled back in the direction.

The injection device 1 further comprises a blocking system for holding the piston rod 30 in a proximal stationary position. The blocking system includes a locking member 50 configured to engage the piston rod. The locking member is under the force of a spring 31 for the locking member to hold the piston rod 30 in a proximal stationary position and for the locking member to inject the composition contained in the medical container 40. It is movable to and from an open position that allows the piston rod 30 to be moved from the proximal stationary position to the distal operating position. The blocking system is described by several embodiments in the presented document below.

According to the first embodiment, the locking member is an insert 50 adapted to be removably inserted into a transverse hole 34 provided within the piston rod 30. The transverse hole 34 is a through hole that extends perpendicular to the axis (A) and preferably extends across the piston rod. The insert 50 is represented in a non-limiting embodiment pinned in FIGS. 1-5, but may be of another form, provided that the insert can perform its function as described. Good.

According to the first alternative of the first embodiment shown in FIGS. 1-4, the insert 50 is adapted to slide on the proximal wall 15 of the body 10 opposite the medical container 40. To. Preferably, the insert 34 is slid towards or away from the piston rod 30 within a notch 51 located on the proximal wall 15 of the body 10 extending radially to the piston rod 30. Is adapted to. In other words, the longitudinal axis (B) of the notch 51 is perpendicular to the axis (A) of the piston rod 30. When the hole 34 of the piston rod is a through hole, the notches 51 preferably pass through the proximal wall 15 of the body 10 on both sides of the piston rod 30 from one point around the proximal wall to another. Extends to. Alternatively, the notch can extend only to one side of the piston rod 30 through only a portion of the proximal wall 15 of the body 10.

As shown in FIG. 3A, when the piston rod 30 is in the proximal stationary position, the transverse hole 34 of the piston rod 30 is substantially radially aligned with the proximal wall 15 of the body and the notch 51 , Radially aligned with the transverse hole 34, thus allowing the insert 50 to be inserted into it. At this position, the spring 31 is compressed and the distal end of the piston rod 30 moves away from the stopper 44.

To carry out the injection, the insert 50 is removed from the transverse hole 34 of the piston rod 30 and slid rearward away from the piston rod, as shown in FIG. 3B. As a result, the spring 31 translates the piston rod 30 in the distal direction from the proximal stationary position to the operating position, at which the piston rod 30 engages the stopper 44 and the composition , Is ejected from the syringe 40 via the needle 43. This movement of the piston rod 30 is due to the spring force of the spring 31, which returns the spring to a relaxed state, where the spring is released. Therefore, the piston rod 30 can be moved without user intervention, thereby facilitating injection.

At the end of the injection shown in FIG. 4, the entire composition has been injected. The stopper 44 is in contact with the distal end 42 of the medical container 40, and the piston rod 30 cannot move further distally. The spring 31 is at least partially relaxed so that the proximal portion of the piston rod 30 in the vicinity of its proximal end 32 remains outside the body 10 so that the user can subsequently inject. Allows the piston rod 30 to be pulled back to the proximal resting position to do this. The piston rod 30 is then blocked by the insert 50 and the empty medical container 40 can be removed from the container holder system and replaced by another prefilled medical container for another injection.

In the following, the features of devices other than the blocking system will not be described again because these features and functions are similar to those described above, taking into account the structural differences of the devices due to different embodiments.

According to the second alternative of the first embodiment shown in FIG. 5, the insert 50 forms a passage extending radially to the piston rod 30, preferably from one side to the other side of the peripheral wall 11. It is adapted to slide towards or away from the piston rod 30 within the transverse opening 18 provided within the perimeter wall 11 of the body 10. In other words, the longitudinal axis (B) of the transverse opening is perpendicular to the axis (A) of the piston rod 30.

When the piston rod 30 is in the proximal stationary position, the transverse opening 18 is aligned with the hole 34 of the piston rod 30. The insert 50 is radially inserted into the transverse opening 18 of the body 10 and the hole 34 of the piston rod 30 thereby keeping the piston rod in a proximal stationary position. The transverse opening 18 can be positioned at different locations on the perimeter wall 11. For example, the transverse opening may be positioned between the first flange 13 and the internal volume 17 of the body 10. In another form, the transverse opening can be radially aligned and positioned with the internal volume 17 of the body 10 to connect to this internal volume. In this latter case, the spring coil is advantageously adapted so that the insert 50 can pass through the piston rod 30 through the transverse hole 34. For example, the distance between adjacent coils of the spring is greater than the diameter of the insert 50.

To carry out the injection, the insert 50 is removed from the hole 34 and the transverse opening 18 of the piston rod, allowing the piston rod 30 to be moved to the distal operating position.

According to the second embodiment shown in FIG. 6, the piston rod 30 does not have the transverse hole as described above. The locking member is an insert 50 as described in the first embodiment. The insert 50 is adapted to slide within the transverse opening 18 provided within the perimeter wall 11 of the body 10. The transverse opening 18 has a structure similar to that of the first embodiment. The transverse opening 18 is radially aligned with and connected to the internal volume 17 of the body 10 and is positioned distally from the piston rod 30 when the piston rod is in the proximal stationary position. To. In particular, the transverse opening 18 may be provided between the second flange 14 of the body 10 and the piston rod 30 when the piston rod 30 is in the proximal stationary position. Since the piston rod 30 is in the proximal stationary position when the insert 50 is inserted into the transverse opening of the body 10, the insert 50 extends across the internal volume of the body 10 and is far from the piston rod 30. The position end 33 abuts the insert 50, thereby keeping the piston rod in a proximal stationary position.

To carry out the injection, the insert 50 is removed from the transverse opening 18. Therefore, the distal end 33 of the piston rod 30 no longer comes into contact with the insert 50 and the piston rod moves to the distal operating position.

According to the third embodiment shown in FIGS. 7 and 8, the piston rod 30 is provided with a narrowed section 35 having a reduced diameter as compared to that of the piston rod 30. The locking member is a latch 60 provided with a first hole 61 and a second hole 62 communicating with each other. The diameter of the first hole 61 is smaller than the diameter of the piston rod 30 and is configured to accommodate only the narrowed section 35 of the piston rod. The diameter of the second hole 62 is larger than the diameter of the piston rod 30 and is configured to accommodate the piston rod.

The latch 60 is preferably radially slidable relative to the body 10 and the piston rod 30 on the proximal wall 15 of the body 10 by pushing and pulling the actuating zone 63.

As shown in FIG. 9A, when the piston rod 30 is in the proximal stationary position, the first hole 61 is aligned with the piston rod 30 and accommodates the narrowed section 35 of the piston rod. The piston rod abuts the latch 60, thereby maintaining it in a proximal stationary position.

To perform the injection, the latch 60 is radially inwardly slid by pushing the working zone 63, thereby aligning the second hole 62 with the piston rod 30 as shown in FIG. 9B. .. The piston rod 30 passes through the second hole 62 and is thus moved from the proximal stationary position to the operating position.

The advantage of this embodiment is that the latch remains attached to the device throughout its use and therefore cannot be lost even after the piston rod has been released.

According to the fourth embodiment shown in FIGS. 10 and 11, the piston rod 30 is provided with a toothed rack 36. The blocking system comprises a button 71, preferably a spring loaded button, mounted on the body 10 of the device 1 and coupled to a locking member which is a wing 70. The wing 70 is pivotally mounted on a structure fixed to the body 10 in the form of two preferably curved branches 72 that join the first flange 13 to the peripheral wall 11 of the body 10. To. The body 10 of the device is provided with a housing 73 configured to accommodate the wings.

As shown in FIG. 10, the button is released and the wing engages the toothed rack. The piston rod 30 is in the proximal stationary position.

To perform the injection, the button 71 is pushed inward in the radial direction (as indicated by the arrow), pivoting the wing 70 around the curved branch 72, away from the piston rod 30, and toothed rack. It disengages from 36, which allows the piston rod to move from the proximal rest position to the operating position.

Regardless of the embodiment of the blocking system, at the end of the injection, the device can be manually reset by the user to proceed to another injection. To do so, the piston rod 30 is pulled proximally by the user, preferably by gripping the radially enlarged proximal end 32, and the locking member returns to the proximal resting position. Moved to the locked position. The empty medical container 40 can then be removed from the container holder system 20 and a new filled medical container 40 can be positioned within the container holder system 20.

The spring 31 is advantageously selected according to the viscosity of the composition to be injected, and more generally according to the difficulty of performing the injection. For example, in the case of a highly viscous composition, the spring with the higher spring force must be preferentially selected.

While performing the injection, the user can push the proximal end 32 of the piston rod 30 distally. In this case, the force applied to the piston rod 30 is a combination of the spring force and the force exerted by the user. In this way, the movement of the piston rod 30 can be accelerated, and the injection flow rate is thus increased. When the user stops pushing the piston rod 30, the piston rod is again driven only by the spring 31.

According to the first embodiment, the second embodiment, and the third embodiment of the device, when the locking members 50, 60, and 70 are in the released position, the piston rod 30 moves in the distal direction and is injected. Keep moving until the end.

According to a fourth embodiment of the device, the injection continues as long as the user holds down the button 71. When the user releases the button, the injection stops. Thus, the user can selectively start and stop the injection by pressing or releasing the buttons, respectively.

The injection device assembly is advantageously provided with a spacer 80 that is in contact with the stopper 44 and positioned within the container 40 before mounting the container 40 on the device 1. The spacer 80 preferably comprises a protrusion 81 on its distal end, which protrusion is inserted into a corresponding recess 45 on the proximal end of the stopper 44, thereby the stopper 44 and the spacer 80. Are fixed together and slide together in the container 40 when pushed by the piston rod 30.

The spacer 80 absorbs a part of the mechanical force transmitted to the stopper 44 by the piston rod 30 when the piston rod comes into indirect contact with the stopper. Therefore, when pushed by the piston rod 30 via the spacer 80, the stopper 44 moves continuously and smoothly. To achieve this, the spacer 80 is advantageously made from a rigid material such as plastic or metal, the length of which provides the space between the proximal end of the medical container and the surface of the composition. It is adapted relative to the amount of composition contained in the medical container so as to reduce. The smaller the amount of composition, the longer the spacer.

The proximal end of the spacer 80 is adapted to contact the distal end of the piston rod 30, and the contact surface between the spacer 80 and the piston rod 30 is preferably a flat surface. The mechanical force is distributed over the entire flat surface, thus improving the movement of the spacer 80 with the stopper 44.

Claims (14)

A supportive injection device (1) for injecting the composition contained in the medical container (40).
The body (10), the body (10), adapted to accept the medical container (40) in a fixed position with respect to the body (10) and is configured to be held by the user's hand. When,
A spring-loaded piston rod (30) with a proximal stationary position inside the body (10) that allows the medical container (40) to be inserted into the body (10) and the piston rod (10). A spring in which the 30) engages with the stopper (44) of the medical container (40) and can be translated in translation with the distal operating position that pushes the stopper (44) into the medical container (40). With the loaded piston rod
A blocking system including locking members (50, 60, 70) mounted on the body (10) and configured to engage the piston rod, wherein the locking member is the body. The piston rod (30) cooperates with the locking position to hold the piston rod (30) in the proximal stationary position, and the locking member cooperates with the main body to hold the piston rod (30) under the force of the spring (31). ) With a blocking system that is movable to and from an open position that allows the proximal stationary position to be moved to the distal operating position.
The piston rod (30) is a proximal end (32) extending out of the body (10) and is far away by the user when the locking member (50, 60, 70) is in the released position. A supportive injection device including a proximal end configured to be pushed in a position direction to accelerate the movement of the piston rod (30) to the distal operating position. The piston rod (30) is provided with a transverse hole (34), and the locking member is radially inserted into the transverse hole (34) of the piston rod (30) when in the locked position. The assisted injection device (1) of claim 1, which is an insert (50) that is removed from the transverse hole (34) when in the open position. The assisted injection device (1) according to claim 2, wherein the insert (50) is slidable on the proximal wall (15) of the body (10) opposite the medical container (40). .. The proximal wall (15) of the body (10) comprises a notch (51) adapted to slidably receive the insert (50) inside, and the notch (51) is said. The third aspect of claim 3, wherein the piston rod (30) extends radially to the piston rod (30) and is aligned with the hole (34) of the piston rod (30) when the piston rod (30) is in the proximal stationary position. Assisted injection device (1). The peripheral wall (11) of the main body (10) of the device (1) is provided with a transverse opening (18) forming a transverse passage through the main body (10) and is in the locked position. When, the insert (50) is radially inserted into the transverse opening (18) of the main body (10), and the hole (30) of the piston rod (30) aligned with the transverse opening (30). 34) The assisted injection device (1) of claim 2, wherein the insert (50) is removed from the transverse opening (18) when in the open position across 34). The peripheral wall (11) of the main body (10) of the device (1) is provided with a transverse opening (18) forming a transverse passage through the main body (10) and is in the locked position. When the insert (50) is radially inserted into the transverse opening (18) of the body (10) and distally from the piston rod (30), the piston rod is thereby inserted into the insert. The assisted injection device (1) according to claim 1, wherein the insert (50) is removed from the transverse through hole (34) when in contact with and in the open position. The piston rod (30) is provided with a narrowed section (35), and the locking member is a latch provided with at least a first hole (61) and a second hole (62) communicating with each other. (60), the diameter of the first hole (61) is smaller than the diameter of the piston rod (30), and the diameter of the second hole (62) is larger than the diameter of the piston rod (30). The latch (60) is aligned with the locking position where the first hole (61) is aligned with the piston rod (30) and accommodates the narrowed section (35) of the piston rod (30). The support type according to claim 1, wherein the second hole (62) is aligned with the piston rod (30) and is slidable in the radial direction with the release position crossed by the piston rod. Injection device (1). The assisted injection device (1) according to claim 7, wherein the latch (60) is slidable on the proximal wall (15) of the body (10) opposite the medical container (40). ). The piston rod (30) is provided with a toothed rack (36), and the blocking system is mounted on the body (10) of the device (1) and onto the locking member which is a wing (70). A combined button (71) is provided, the wing (70) is pivotally mounted on a structure (72) fixed to the body (10), and the wing (70) is the button (70). The wing (71) is released, the lock position where the wing (70) engages with the toothed rack (36) to block the piston rod (30), and the button (71) is pressed to push the wing (71). The first aspect of claim 1, wherein the 70) is pivotally movable to and from the release position which allows the piston rod (30) to be moved by disengaging from the toothed rack (36). Assisted injection device (1). The assisted injection device (1) according to claim 9, wherein the button (71) is a spring-loaded button. The body (10) is a container holder system (20) that is configured to receive at least a portion of the medical container (40) and moves from the proximal stationary position to the distal operating position. The medical treatment is such that the piston rod (30) engages with the stopper (44) of the medical container (40) and pushes the stopper (44) into the medical container (40) to inject the composition. The assisted injection device according to any one of claims 1 to 10, comprising a container holder system configured to align and hold the container (40) with the moving direction of the piston rod (30). 1). The container holder system (20)
In a housing (22) configured to accept at least a portion of the medical container (40) and keep the medical container (40) in a fixed position aligned with the direction of movement of the piston rod (30). With the slot (21) provided in the peripheral wall (11) of the connecting body (10),
A through groove (23) provided in the distal wall (16) of the body (10), continuous with the slot (21), and extending from the slot (21) into the distal wall (16). 23. The groove (23) includes a through groove configured to guide the medical container (40) inserted into the housing (22) through the slot (21). 11. The assisted injection device (1). The assisted injection device assembly includes the assisted injection device (1) according to any one of claims 1 to 12 and a medical container (40) mounted on the assisted injection device. Assisted injection device assembly. The assembly further comprises a spacer (80) configured to be secured to the stopper (44), wherein the piston rod (30) is distal to the proximal stationary position. 13. The assistive injection device assembly of claim 13, configured to be contacted by the piston rod (30) and pushed together with the stopper (44) when moving to an operating position.

Images