JP2020524167A5 - - Google Patents
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- Publication number
- JP2020524167A5 JP2020524167A5 JP2019570568A JP2019570568A JP2020524167A5 JP 2020524167 A5 JP2020524167 A5 JP 2020524167A5 JP 2019570568 A JP2019570568 A JP 2019570568A JP 2019570568 A JP2019570568 A JP 2019570568A JP 2020524167 A5 JP2020524167 A5 JP 2020524167A5
- Authority
- JP
- Japan
- Prior art keywords
- cells
- medicament according
- subject
- merkel cell
- agonist
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 210000004027 cell Anatomy 0.000 claims description 31
- 208000002030 Merkel cell carcinoma Diseases 0.000 claims description 16
- 208000017763 cutaneous neuroendocrine carcinoma Diseases 0.000 claims description 16
- 239000000556 agonist Substances 0.000 claims description 15
- 206010029266 Neuroendocrine carcinoma of the skin Diseases 0.000 claims description 11
- 241000579048 Merkel cell polyomavirus Species 0.000 claims description 4
- 238000002512 chemotherapy Methods 0.000 claims description 4
- 108010057840 ALT-803 Proteins 0.000 claims description 2
- 206010028980 Neoplasm Diseases 0.000 claims description 2
- 230000001394 metastastic effect Effects 0.000 claims description 2
- 206010061289 metastatic neoplasm Diseases 0.000 claims description 2
- 238000001959 radiotherapy Methods 0.000 claims description 2
- 238000001356 surgical procedure Methods 0.000 claims description 2
- 238000002560 therapeutic procedure Methods 0.000 claims description 2
- 239000003814 drug Substances 0.000 claims 20
- 229940079593 drug Drugs 0.000 claims 3
- 238000001990 intravenous administration Methods 0.000 claims 1
- 238000007911 parenteral administration Methods 0.000 claims 1
- 238000000034 method Methods 0.000 description 25
- 201000011510 cancer Diseases 0.000 description 1
- 238000001802 infusion Methods 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201762522319P | 2017-06-20 | 2017-06-20 | |
| US62/522,319 | 2017-06-20 | ||
| PCT/US2018/038312 WO2018236890A1 (en) | 2017-06-20 | 2018-06-19 | Nk-92 cells and il-15 agonist combination therapy |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2020524167A JP2020524167A (ja) | 2020-08-13 |
| JP2020524167A5 true JP2020524167A5 (https=) | 2021-09-30 |
Family
ID=62875319
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019570568A Pending JP2020524167A (ja) | 2017-06-20 | 2018-06-19 | Ｎｋ−９２細胞とｉｌ−１５アゴニストの併用療法 |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US20200121720A1 (https=) |
| EP (1) | EP3641799A1 (https=) |
| JP (1) | JP2020524167A (https=) |
| KR (1) | KR20200017495A (https=) |
| CN (1) | CN110740747A (https=) |
| AU (1) | AU2018288715A1 (https=) |
| CA (1) | CA3066465A1 (https=) |
| IL (1) | IL270840A (https=) |
| WO (1) | WO2018236890A1 (https=) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20220160479A (ko) * | 2021-05-27 | 2022-12-06 | (주)에스엠티바이오 | 신경내분비종양의 치료용 자연살해세포 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ATE323756T1 (de) | 1997-04-30 | 2006-05-15 | Hans Klingemann | Natürliche killerzelllinien und verfahren zu ihrer verwendung |
| ES2367027T3 (es) | 2004-02-27 | 2011-10-27 | Inserm (Institut National De La Santé Et De La Recherche Medicale) | Sitio de unión de la il-15 para il-15ralfa y mutantes específicos de il-15 que tienen actividad agonista/antagonista. |
| CN101743249B (zh) | 2007-05-11 | 2017-08-08 | 阿尔托生物科学有限公司 | 融合分子与il‑15变异体 |
| US8507222B2 (en) | 2010-09-21 | 2013-08-13 | Altor Bioscience Corporation | Multimeric IL-15 soluble fusion molecules and methods of making and using same |
-
2018
- 2018-06-19 US US16/620,791 patent/US20200121720A1/en not_active Abandoned
- 2018-06-19 CA CA3066465A patent/CA3066465A1/en not_active Abandoned
- 2018-06-19 EP EP18740021.3A patent/EP3641799A1/en not_active Withdrawn
- 2018-06-19 AU AU2018288715A patent/AU2018288715A1/en not_active Abandoned
- 2018-06-19 JP JP2019570568A patent/JP2020524167A/ja active Pending
- 2018-06-19 WO PCT/US2018/038312 patent/WO2018236890A1/en not_active Ceased
- 2018-06-19 KR KR1020207001267A patent/KR20200017495A/ko not_active Ceased
- 2018-06-19 CN CN201880039278.6A patent/CN110740747A/zh active Pending
-
2019
- 2019-11-21 IL IL270840A patent/IL270840A/en unknown
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