JP2020522506A5 - - Google Patents
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- JP2020522506A5 JP2020522506A5 JP2019566594A JP2019566594A JP2020522506A5 JP 2020522506 A5 JP2020522506 A5 JP 2020522506A5 JP 2019566594 A JP2019566594 A JP 2019566594A JP 2019566594 A JP2019566594 A JP 2019566594A JP 2020522506 A5 JP2020522506 A5 JP 2020522506A5
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| CN114364405B (zh) * | 2019-04-26 | 2024-07-16 | 五一一制药股份有限公司 | 作为诊断剂和放射性核素治疗剂的前列腺特异性膜抗原(psma)抑制剂 |
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| CN114341118A (zh) * | 2019-07-02 | 2022-04-12 | 先进加速器应用意大利公司 | 前列腺特异性膜抗原(psma)配体及其用途 |
| WO2021202376A1 (en) * | 2020-03-30 | 2021-10-07 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Method for blocking uptake of prostate-specific membrane antigen (psma)-targeted radionuclides by exocrine organs |
| JP2023522983A (ja) * | 2020-04-24 | 2023-06-01 | ラジオメディックス インコーポレイテッド | 前立腺がんの診断および処置のための組成物、キットおよび方法 |
| CA3178858A1 (en) * | 2020-05-06 | 2021-11-11 | Cornell University | Copper-containing theragnostic compounds and methods of use |
| EP4196175A4 (en) * | 2020-08-14 | 2025-07-30 | Clarity Pharmaceuticals Ltd | RADIOPHARMACEUTICAL COMPOUNDS, THEIR USES AND PROCESSES FOR THEIR PRODUCTION |
| EP4204020A1 (en) * | 2020-08-31 | 2023-07-05 | Advanced Accelerator Applications International S.A. | Method of treating psma-expressing cancers |
| US20230321285A1 (en) * | 2020-08-31 | 2023-10-12 | Advanced Accelerator Applications International Sa | Method of treating psma-expressing cancers |
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| CN113077840B (zh) * | 2021-04-21 | 2023-01-31 | 四川大学 | 基于药效团与alpha-碳特征的金属酶活性位点对比方法 |
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| US9422234B2 (en) | 2007-11-30 | 2016-08-23 | The Johns Hopkins University | Prostate specific membrane antigen (PSMA) targeted nanoparticles for therapy of prostate cancer |
| CA2745918C (en) * | 2008-12-05 | 2017-10-10 | Molecular Insight Pharmaceuticals, Inc. | Technetium- and rhenium-bis(heteroaryl) complexes and methods of use thereof |
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| EP2739316B1 (en) * | 2011-08-05 | 2019-04-10 | Molecular Insight Pharmaceuticals, Inc. | Radiolabeled prostate specific membrane antigen inhibitors |
| US9371360B2 (en) * | 2011-11-30 | 2016-06-21 | The Johns Hopkins University | Homomultivalent and heteromultivalent inhibitors of prostate specific membrane antigen (PSMA) and uses thereof |
| JP6468602B2 (ja) | 2013-01-14 | 2019-02-13 | モレキュラ インサイト ファーマシューティカルズ インコーポレイテッド | トリアジン系放射性医薬品及び放射線造影剤 |
| EP2862857A1 (en) * | 2013-10-18 | 2015-04-22 | Deutsches Krebsforschungszentrum | Labeled inhibitors of prostate specific membrane antigen (PSMA), their use as imaging agents and pharmaceutical agents for the treatment of prostate cancer |
| HUE066137T2 (hu) * | 2013-10-18 | 2024-07-28 | Novartis Ag | A prosztata-specifikus membrán antigén (PSMA) jelzett inhibitorai, alkalmazásuk képalkotásban és gyógyszerkészítmények prosztatarák kezelésére |
| EP3140282B1 (en) * | 2014-05-06 | 2019-07-10 | The Johns Hopkins University | Metal/radiometal-labeled psma inhibitors for psma-targeted imaging and radiotherapy |
| PL3183236T3 (pl) * | 2014-08-24 | 2022-07-18 | Max-Planck-Gesellschaft Zur Förderung Der Wissenschaften | Sposób wytwarzania 18f-znakowanych aktywnych estrów i ich zastosowanie na przykładzie wytwarzania znacznika pet specyficznego dla psma |
| JP2017530109A (ja) * | 2014-09-08 | 2017-10-12 | モレキュラ インサイト ファーマシューティカルズ インコーポレイテッド | 前立腺癌についてのpsmaを標的とした放射性核種治療中の臓器の保護 |
| US11420910B2 (en) * | 2014-10-30 | 2022-08-23 | Katholieke Universitet Leuven | Methods for low temperature fluorine-18 radiolabeling of biomolecules |
| US10688200B2 (en) * | 2015-12-31 | 2020-06-23 | Five Eleven Pharma Inc. | Urea-based prostate specific membrane antigen (PSMA) inhibitors for imaging and therapy |
| SI3925952T1 (sl) * | 2016-03-22 | 2024-03-29 | The Johns Hopkins University | Za prostato specifična, na membranski antigen usmerjena visoko afinitetna sredstva za endoradioterapijo raka prostate |
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2022
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2024
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