JP2020520924A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2020520924A5 JP2020520924A5 JP2019563596A JP2019563596A JP2020520924A5 JP 2020520924 A5 JP2020520924 A5 JP 2020520924A5 JP 2019563596 A JP2019563596 A JP 2019563596A JP 2019563596 A JP2019563596 A JP 2019563596A JP 2020520924 A5 JP2020520924 A5 JP 2020520924A5
- Authority
- JP
- Japan
- Prior art keywords
- alkyl
- cycloalkyl
- haloalkyl
- heterocyclyl
- compound according
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 0 *C(*)(*N)*=C Chemical compound *C(*)(*N)*=C 0.000 description 1
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2021146775A JP7241825B2 (ja) | 2017-05-17 | 2021-09-09 | キナーゼ阻害剤およびその使用 |
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201762507698P | 2017-05-17 | 2017-05-17 | |
| US62/507,698 | 2017-05-17 | ||
| US201862664895P | 2018-04-30 | 2018-04-30 | |
| US62/664,895 | 2018-04-30 | ||
| PCT/US2018/033266 WO2018213632A1 (en) | 2017-05-17 | 2018-05-17 | Kinase inhibitors and uses thereof |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021146775A Division JP7241825B2 (ja) | 2017-05-17 | 2021-09-09 | キナーゼ阻害剤およびその使用 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2020520924A JP2020520924A (ja) | 2020-07-16 |
| JP2020520924A5 true JP2020520924A5 (https=) | 2021-07-26 |
| JP7064512B2 JP7064512B2 (ja) | 2022-05-10 |
Family
ID=64274744
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019563596A Active JP7064512B2 (ja) | 2017-05-17 | 2018-05-17 | キナーゼ阻害剤およびその使用 |
| JP2021146775A Active JP7241825B2 (ja) | 2017-05-17 | 2021-09-09 | キナーゼ阻害剤およびその使用 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021146775A Active JP7241825B2 (ja) | 2017-05-17 | 2021-09-09 | キナーゼ阻害剤およびその使用 |
Country Status (21)
| Country | Link |
|---|---|
| US (3) | US11203600B2 (https=) |
| EP (1) | EP3624797A4 (https=) |
| JP (2) | JP7064512B2 (https=) |
| KR (1) | KR102638151B1 (https=) |
| CN (3) | CN119285572A (https=) |
| AU (1) | AU2018269743B2 (https=) |
| BR (1) | BR112019023918A2 (https=) |
| CA (1) | CA3063934A1 (https=) |
| CL (1) | CL2019003263A1 (https=) |
| CO (1) | CO2019012957A2 (https=) |
| CR (1) | CR20190566A (https=) |
| DO (1) | DOP2019000290A (https=) |
| EC (1) | ECSP19089214A (https=) |
| IL (1) | IL270648B2 (https=) |
| MX (2) | MX2019013645A (https=) |
| MY (1) | MY200328A (https=) |
| PE (2) | PE20200729A1 (https=) |
| PH (1) | PH12019550235A1 (https=) |
| SG (1) | SG10201913927VA (https=) |
| TW (1) | TWI794232B (https=) |
| WO (1) | WO2018213632A1 (https=) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20220072019A1 (en) * | 2018-10-19 | 2022-03-10 | Disarm Therapeutics, Inc. | Inhibitors of sarm1 in combination with nad+ or a nad+ precursor |
| IL291665B2 (en) | 2019-09-27 | 2025-07-01 | Univ Texas | Inhibitors of receptor interacting protein kinase i for the treatment of disease |
| TWI873290B (zh) * | 2020-02-13 | 2025-02-21 | 德商百靈佳殷格翰國際股份有限公司 | 作為血漿激肽釋放酶抑制劑之雜芳族甲醯胺衍生物 |
| WO2021187605A1 (ja) * | 2020-03-19 | 2021-09-23 | 田辺三菱製薬株式会社 | 含窒素複素環αシアノカルボニル化合物 |
| TW202214617A (zh) | 2020-06-02 | 2022-04-16 | 法商賽諾菲公司 | 作為ｒｉｐｋ１抑制劑之異㗁唑啶及其用途 |
| KR200493347Y1 (ko) | 2020-07-06 | 2021-03-17 | 박혜진 | 휴대가 용이한 마스크 |
| TW202302565A (zh) * | 2021-02-19 | 2023-01-16 | 英商卡爾維斯塔製藥有限公司 | 酶抑制劑 |
| WO2022231927A1 (en) * | 2021-04-27 | 2022-11-03 | Merck Sharp & Dohme Llc | Phenyl azepines as ripk1 inhibitors and methods of use thereof |
| WO2022231928A1 (en) * | 2021-04-27 | 2022-11-03 | Merck Sharp & Dohme Llc | Ripk1 inhibitors and methods of use |
| WO2023083847A1 (en) | 2021-11-11 | 2023-05-19 | Sanofi | Isoxazolidines as ripk1 inhibitors and use thereof |
| WO2024025817A1 (en) * | 2022-07-25 | 2024-02-01 | Denali Therapeutics Inc. | Solid forms of 4-(3,3-difluoro-2,2-dimethyl-propanoyl)-3,5- dihydro-2h-pyrido[3,4-f][l,4]oxazepine-9-carbonitrile |
| TW202412812A (zh) * | 2022-08-23 | 2024-04-01 | 美商建新公司 | 用於治療受體相互作用蛋白激酶１介導的疾病的方法 |
| WO2024158665A1 (en) * | 2023-01-23 | 2024-08-02 | Genzyme Corporation | Drug formulations of 4-(3,3-difluoro-2,2-dimethyl-propanoyl)-3,5-dihydro-2h-pyrido [3,4-f] [1,4] oxazepine-9-c arbonitrile |
| WO2025006575A1 (en) * | 2023-06-27 | 2025-01-02 | Genzyme Corporation | Process for preparing 4-(3,3-difluoro-2,2-dimethyl-propanoyl)-3,5-dihydro-2h-pyrido[3,4-f][l,4]oxazepine-9-carbonitrile |
| CN120365287A (zh) * | 2024-01-23 | 2025-07-25 | 南京天印健华医药科技有限公司 | 作为ripk1抑制剂的杂环化合物 |
| CN120365288A (zh) * | 2024-01-23 | 2025-07-25 | 南京天印健华医药科技有限公司 | 作为ripk1抑制剂的杂环化合物 |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP3861187B2 (ja) * | 1996-08-02 | 2006-12-20 | 住友精化株式会社 | チアゼピン誘導体の製造方法 |
| CA2423902A1 (en) | 2000-09-27 | 2003-03-26 | Ajinomoto Co., Inc. | Benzodiazepine derivative |
| RU2456287C1 (ru) * | 2011-05-20 | 2012-07-20 | Николай Филиппович Савчук | Стимуляторы секреции инкретиновых гормонов, способы их получения и применения |
| TW201837023A (zh) | 2011-07-01 | 2018-10-16 | 美商基利科學股份有限公司 | 作為離子通道調節劑之稠合雜環化合物 |
| TWI648274B (zh) | 2013-02-15 | 2019-01-21 | 英商葛蘭素史克智慧財產發展有限公司 | 作為激酶抑制劑之雜環醯胺類 （二） |
| CN104059068B (zh) | 2013-03-20 | 2017-02-08 | 中国科学院上海药物研究所 | β‑氨基羰基类化合物、其制备方法、药物组合物及其用途 |
| SG11201708622UA (en) * | 2015-02-02 | 2017-11-29 | Forma Therapeutics Inc | 3-aryl-4-amido-bicyclic [4,5,0] hydroxamic acids as hdac inhibitors |
| TWI730959B (zh) * | 2015-05-19 | 2021-06-21 | 英商葛蘭素史克智慧財產發展有限公司 | 作為激酶抑制劑之雜環醯胺 |
| LT3307739T (lt) * | 2015-06-15 | 2021-03-10 | Glaxosmithkline Intellectual Property Development Limited | Nrf2 reguliatoriai |
-
2018
- 2018-05-17 JP JP2019563596A patent/JP7064512B2/ja active Active
- 2018-05-17 SG SG10201913927VA patent/SG10201913927VA/en unknown
- 2018-05-17 CN CN202411240962.4A patent/CN119285572A/zh active Pending
- 2018-05-17 MX MX2019013645A patent/MX2019013645A/es unknown
- 2018-05-17 WO PCT/US2018/033266 patent/WO2018213632A1/en not_active Ceased
- 2018-05-17 EP EP18802127.3A patent/EP3624797A4/en active Pending
- 2018-05-17 CN CN201880047293.5A patent/CN110913858B/zh active Active
- 2018-05-17 AU AU2018269743A patent/AU2018269743B2/en active Active
- 2018-05-17 MY MYPI2019006664A patent/MY200328A/en unknown
- 2018-05-17 CN CN202411240964.3A patent/CN119264073A/zh active Pending
- 2018-05-17 KR KR1020197036911A patent/KR102638151B1/ko active Active
- 2018-05-17 IL IL270648A patent/IL270648B2/en unknown
- 2018-05-17 PE PE2019002424A patent/PE20200729A1/es unknown
- 2018-05-17 CR CR20190566A patent/CR20190566A/es unknown
- 2018-05-17 CA CA3063934A patent/CA3063934A1/en active Pending
- 2018-05-17 BR BR112019023918-9A patent/BR112019023918A2/pt not_active Application Discontinuation
- 2018-05-17 TW TW107116834A patent/TWI794232B/zh active
- 2018-05-17 PE PE2024000411A patent/PE20241932A1/es unknown
-
2019
- 2019-11-13 PH PH12019550235A patent/PH12019550235A1/en unknown
- 2019-11-14 MX MX2022010755A patent/MX2022010755A/es unknown
- 2019-11-14 DO DO2019000290A patent/DOP2019000290A/es unknown
- 2019-11-14 US US16/684,340 patent/US11203600B2/en active Active
- 2019-11-14 CL CL2019003263A patent/CL2019003263A1/es unknown
- 2019-11-19 CO CONC2019/0012957A patent/CO2019012957A2/es unknown
- 2019-12-16 EC ECSENADI201989214A patent/ECSP19089214A/es unknown
-
2021
- 2021-09-09 JP JP2021146775A patent/JP7241825B2/ja active Active
- 2021-10-26 US US17/511,193 patent/US12129263B2/en active Active
-
2024
- 2024-09-18 US US18/889,058 patent/US20250011338A1/en active Pending
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2020520924A5 (https=) | ||
| TWI877177B (zh) | 作為NAv1.8抑制劑之2,3-二氫喹唑啉化合物 | |
| JP6655052B2 (ja) | ビヘテロアリール化合物及びその使用 | |
| DE69915675T2 (de) | Triazolo[4,5-d]pyrimidin-derivate | |
| JP7576581B2 (ja) | イミダゾ［１，２－ａ］ピリジニル誘導体及び疾患の処置におけるそれらの使用 | |
| JP5036947B2 (ja) | トリアゾロ［４，５−ｄ］ピリミジン化合物の新規な結晶形及び非晶形 | |
| JP2022517410A (ja) | イミダゾ［１，２－ａ］ピリジニル誘導体及び疾患の処置におけるその使用 | |
| AU2007227203B2 (en) | 6,7,8, 9 -tetrahydro- 5H- pyrimido [4, 5-d] azepin-4-yl] -amine derivatives as modulators of TRPVL for the treatment of pain | |
| JP2014531458A5 (https=) | ||
| WO2007013673A1 (en) | Fused heterocycles as lck inhibitors | |
| CA2764728A1 (en) | Janus kinase inhibitor compounds and methods | |
| CA2846692A1 (en) | 6h-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepines | |
| KR102111570B1 (ko) | 신규 이미다조피리다진 화합물 및 그의 용도 | |
| WO2012080284A2 (en) | Substituted 6,6-fused nitrogenous heterocyclic compounds and uses thereof | |
| KR20150036738A (ko) | 신규 헤테로아릴 및 헤테로사이클 화합물, 그의 조성물 및 방법 | |
| JP2016513118A (ja) | ４−置換されたピロロ−およびピラゾロジアゼピン類 | |
| JP2013507417A (ja) | アセチルコリン受容体に関連する疾患の処置のための縮合アジン誘導体 | |
| JP2010508363A5 (https=) | ||
| KR101447789B1 (ko) | Ｎ-7 치환된 퓨린 및 피라졸로피리미딘 화합물, 조성물 및 사용 방법 | |
| JP2014505713A (ja) | Ｃｎｓ障害の処置のための６−シクロアルキル−ピラゾロピリミジノン | |
| CA2788783A1 (en) | Heterocycles as potassium channel modulators | |
| JP2022502444A (ja) | ３−アザビシクロ［３，１，１］ヘプタン誘導体及びこれを含む薬学的組成物 | |
| CA3258709A1 (en) | TRICYCLIC COMPOUNDS AND THEIR USES | |
| JP2017519760A (ja) | ＢＥＴ−タンパク質を阻害するメタ位置換芳香族アミノ又はエーテル基を有する３，４−ジヒドロピリド［２，３−ｂ］ピラジノン類 | |
| AU2010334804B2 (en) | Aminoalkylpyrimidine derivatives as histamine H4 receptor antagonists |