JP2020520755A - 中空プランジャーロッドを備えた自動インジェクタ - Google Patents

中空プランジャーロッドを備えた自動インジェクタ Download PDF

Info

Publication number
JP2020520755A
JP2020520755A JP2019564911A JP2019564911A JP2020520755A JP 2020520755 A JP2020520755 A JP 2020520755A JP 2019564911 A JP2019564911 A JP 2019564911A JP 2019564911 A JP2019564911 A JP 2019564911A JP 2020520755 A JP2020520755 A JP 2020520755A
Authority
JP
Japan
Prior art keywords
syringe
plunger rod
automatic injector
driver
refillable
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2019564911A
Other languages
English (en)
Japanese (ja)
Other versions
JP2020520755A5 (enExample
Inventor
ブラビュア ヤコブセン，ペーター
ブラビュア ヤコブセン，ペーター
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck Patent GmbH
Original Assignee
Merck Patent GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Patent GmbH filed Critical Merck Patent GmbH
Publication of JP2020520755A publication Critical patent/JP2020520755A/ja
Publication of JP2020520755A5 publication Critical patent/JP2020520755A5/ja
Pending legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/20—Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
    • A61M5/2033—Spring-loaded one-shot injectors with or without automatic needle insertion
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31565—Administration mechanisms, i.e. constructional features, modes of administering a dose
    • A61M5/3159—Dose expelling manners
    • A61M5/31593—Multi-dose, i.e. individually set dose repeatedly administered from the same medicament reservoir
    • A61M5/31595—Pre-defined multi-dose administration by repeated overcoming of means blocking the free advancing movement of piston rod, e.g. by tearing or de-blocking
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/32—Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
    • A61M5/3205—Apparatus for removing or disposing of used needles or syringes, e.g. containers; Means for protection against accidental injuries from used needles
    • A61M5/321—Means for protection against accidental injuries by used needles
    • A61M5/3243—Means for protection against accidental injuries by used needles being axially-extensible, e.g. protective sleeves coaxially slidable on the syringe barrel
    • A61M5/326—Fully automatic sleeve extension, i.e. in which triggering of the sleeve does not require a deliberate action by the user
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/50—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests having means for preventing re-use, or for indicating if defective, used, tampered with or unsterile
    • A61M5/5086—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests having means for preventing re-use, or for indicating if defective, used, tampered with or unsterile for indicating if defective, used, tampered with or unsterile
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/20—Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
    • A61M2005/2006—Having specific accessories
    • A61M2005/202—Having specific accessories cocking means, e.g. to bias the main drive spring of an injector
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/20—Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
    • A61M2005/206—With automatic needle insertion
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/20—Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
    • A61M2005/2073—Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically preventing premature release, e.g. by making use of a safety lock
    • A61M2005/208—Release is possible only when device is pushed against the skin, e.g. using a trigger which is blocked or inactive when the device is not pushed against the skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/32—Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
    • A61M5/3205—Apparatus for removing or disposing of used needles or syringes, e.g. containers; Means for protection against accidental injuries from used needles
    • A61M5/321—Means for protection against accidental injuries by used needles
    • A61M5/3243—Means for protection against accidental injuries by used needles being axially-extensible, e.g. protective sleeves coaxially slidable on the syringe barrel
    • A61M5/326—Fully automatic sleeve extension, i.e. in which triggering of the sleeve does not require a deliberate action by the user
    • A61M2005/3267—Biased sleeves where the needle is uncovered by insertion of the needle into a patient's body
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/32—Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
    • A61M5/3202—Devices for protection of the needle before use, e.g. caps

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Environmental & Geological Engineering (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
JP2019564911A 2017-05-23 2018-05-16 中空プランジャーロッドを備えた自動インジェクタ Pending JP2020520755A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP17172564.1 2017-05-23
EP17172564 2017-05-23
PCT/EP2018/062822 WO2018215271A1 (en) 2017-05-23 2018-05-16 Auto injector with hollow plunger rod

Publications (2)

Publication Number Publication Date
JP2020520755A true JP2020520755A (ja) 2020-07-16
JP2020520755A5 JP2020520755A5 (enExample) 2021-07-26

Family

ID=58772477

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2019564911A Pending JP2020520755A (ja) 2017-05-23 2018-05-16 中空プランジャーロッドを備えた自動インジェクタ

Country Status (9)

Country Link
US (1) US20200139046A1 (enExample)
EP (1) EP3630235A1 (enExample)
JP (1) JP2020520755A (enExample)
CN (1) CN110740771A (enExample)
AU (1) AU2018272795A1 (enExample)
BR (1) BR112019024329A2 (enExample)
CA (1) CA3064491A1 (enExample)
RU (1) RU2019139537A (enExample)
WO (1) WO2018215271A1 (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2020520756A (ja) * 2017-05-23 2020-07-16 メルク パテント ゲゼルシャフト ミット ベシュレンクテル ハフツングＭｅｒｃｋ Ｐａｔｅｎｔ Ｇｅｓｅｌｌｓｃｈａｆｔ ｍｉｔ ｂｅｓｃｈｒａｅｎｋｔｅｒ Ｈａｆｔｕｎｇ リキャップ防止を備えた自動インジェクタ

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US12453822B2 (en) 2019-02-26 2025-10-28 Becton Dickinson France Auto-injector with audio indicator
BR102019016950A2 (pt) * 2019-08-15 2021-02-23 Inst De Pesquisa Ensino Ciencia E Tecnologia Aplicada Inst Galzu forma de dosagem intrauretral de medicamento; e dispositivo
WO2021094047A1 (en) * 2019-11-11 2021-05-20 Shl Medical Ag Medicament delivery device
WO2021122190A1 (en) 2019-12-18 2021-06-24 Novo Nordisk A/S Drug delivery device for delivering a predefined fixed dose
WO2024054430A1 (en) * 2022-09-06 2024-03-14 University Hospitals Cleveland Medical Center Auto-injector
EP4647106A1 (en) 2024-05-07 2025-11-12 Instituto Galzu - Pesquisa, Ensino, Ciência e Tecnologia Aplicada Intraurethral administration device and kit
US12397122B1 (en) 2024-08-29 2025-08-26 Genzyme Corporation Medicament delivery device
US12383683B1 (en) * 2024-08-29 2025-08-12 Genzyme Corporation Medicament delivery device

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2014526297A (ja) * 2011-09-09 2014-10-06 メルク パテント ゲゼルシャフト ミット ベシュレンクテル ハフツング 独立した針挿入による自動注射器
US20150250953A1 (en) * 2012-10-12 2015-09-10 Carebay Europe Ltd Medicament Delivery Device
WO2016075254A1 (en) * 2014-11-12 2016-05-19 Novo Nordisk A/S A method of manufacturing one of a range of autoinjectors
JP2020520756A (ja) * 2017-05-23 2020-07-16 メルク パテント ゲゼルシャフト ミット ベシュレンクテル ハフツングＭｅｒｃｋ Ｐａｔｅｎｔ Ｇｅｓｅｌｌｓｃｈａｆｔ ｍｉｔ ｂｅｓｃｈｒａｅｎｋｔｅｒ Ｈａｆｔｕｎｇ リキャップ防止を備えた自動インジェクタ

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5540664A (en) 1993-05-27 1996-07-30 Washington Biotech Corporation Reloadable automatic or manual emergency injection system
US20050101919A1 (en) * 2003-11-07 2005-05-12 Lennart Brunnberg Device for an injector
GB2414405B (en) 2004-05-28 2009-01-14 Cilag Ag Int Injection device
NZ554828A (en) 2004-12-06 2010-07-30 Washington Biotech Corp Medicine injection devices and methods
EP2211944B1 (en) * 2007-09-25 2019-05-22 Becton Dickinson France Autoinjector with deshielder comprising tamper evidence means
IT1398501B1 (it) 2010-03-10 2013-03-01 Menarini Int Operations Lu Sa Dispositivo autoiniettore di due dosi di farmaco
EP2438939A1 (en) 2010-10-08 2012-04-11 Sanofi-Aventis Deutschland GmbH Arrangement for coupling a plunger to either a syringe or a stopper
AU2012302281B2 (en) * 2011-08-31 2015-05-07 Shl Medical Ag Injection device
WO2013058698A1 (en) * 2011-10-17 2013-04-25 Shl Group Ab Medicament delivery device
ES2623081T3 (es) * 2012-04-17 2017-07-10 Carebay Europe Ltd Dispositivo de administración de medicamentos
EP3061478A1 (en) * 2015-02-27 2016-08-31 Sanofi-Aventis Deutschland GmbH Medicament delivery device and method for assembling same

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2014526297A (ja) * 2011-09-09 2014-10-06 メルク パテント ゲゼルシャフト ミット ベシュレンクテル ハフツング 独立した針挿入による自動注射器
US20150250953A1 (en) * 2012-10-12 2015-09-10 Carebay Europe Ltd Medicament Delivery Device
WO2016075254A1 (en) * 2014-11-12 2016-05-19 Novo Nordisk A/S A method of manufacturing one of a range of autoinjectors
JP2020520756A (ja) * 2017-05-23 2020-07-16 メルク パテント ゲゼルシャフト ミット ベシュレンクテル ハフツングＭｅｒｃｋ Ｐａｔｅｎｔ Ｇｅｓｅｌｌｓｃｈａｆｔ ｍｉｔ ｂｅｓｃｈｒａｅｎｋｔｅｒ Ｈａｆｔｕｎｇ リキャップ防止を備えた自動インジェクタ

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2020520756A (ja) * 2017-05-23 2020-07-16 メルク パテント ゲゼルシャフト ミット ベシュレンクテル ハフツングＭｅｒｃｋ Ｐａｔｅｎｔ Ｇｅｓｅｌｌｓｃｈａｆｔ ｍｉｔ ｂｅｓｃｈｒａｅｎｋｔｅｒ Ｈａｆｔｕｎｇ リキャップ防止を備えた自動インジェクタ

Also Published As

Publication number Publication date
BR112019024329A2 (pt) 2020-06-16
WO2018215271A1 (en) 2018-11-29
RU2019139537A3 (enExample) 2021-09-03
CA3064491A1 (en) 2018-11-29
US20200139046A1 (en) 2020-05-07
AU2018272795A1 (en) 2019-12-05
CN110740771A (zh) 2020-01-31
EP3630235A1 (en) 2020-04-08
RU2019139537A (ru) 2021-06-24

Similar Documents

Publication Publication Date Title
AU2019213383B2 (en) An auto-injector for epinephrine injection
JP2020520756A (ja) リキャップ防止を備えた自動インジェクタ
JP2020520755A (ja) 中空プランジャーロッドを備えた自動インジェクタ

Legal Events

Date Code Title Description
A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20210514

A621 Written request for application examination

Free format text: JAPANESE INTERMEDIATE CODE: A621

Effective date: 20210514

A977 Report on retrieval

Free format text: JAPANESE INTERMEDIATE CODE: A971007

Effective date: 20220210

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20220215

A02 Decision of refusal

Free format text: JAPANESE INTERMEDIATE CODE: A02

Effective date: 20220920