JP2020519660A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2020519660A5 JP2020519660A5 JP2019563125A JP2019563125A JP2020519660A5 JP 2020519660 A5 JP2020519660 A5 JP 2020519660A5 JP 2019563125 A JP2019563125 A JP 2019563125A JP 2019563125 A JP2019563125 A JP 2019563125A JP 2020519660 A5 JP2020519660 A5 JP 2020519660A5
- Authority
- JP
- Japan
- Prior art keywords
- inhibitor
- cancer
- item
- combinations
- delta
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2022160828A JP2022176316A (ja) | 2017-05-16 | 2022-10-05 | 異型braf変異を有するがんを処置するための組成物および方法 |
| JP2025100020A JP2025123379A (ja) | 2017-05-16 | 2025-06-16 | 異型braf変異を有するがんを処置するための組成物および方法 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201762506995P | 2017-05-16 | 2017-05-16 | |
| US62/506,995 | 2017-05-16 | ||
| PCT/US2018/032755 WO2018213302A1 (en) | 2017-05-16 | 2018-05-15 | Compositions and methods for treating cancer with atypical braf mutations |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022160828A Division JP2022176316A (ja) | 2017-05-16 | 2022-10-05 | 異型braf変異を有するがんを処置するための組成物および方法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2020519660A JP2020519660A (ja) | 2020-07-02 |
| JP2020519660A5 true JP2020519660A5 (https=) | 2021-07-26 |
| JP7405408B2 JP7405408B2 (ja) | 2023-12-26 |
Family
ID=64274828
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019563125A Active JP7405408B2 (ja) | 2017-05-16 | 2018-05-15 | 異型braf変異を有するがんを処置するための組成物および方法 |
| JP2022160828A Withdrawn JP2022176316A (ja) | 2017-05-16 | 2022-10-05 | 異型braf変異を有するがんを処置するための組成物および方法 |
| JP2025100020A Pending JP2025123379A (ja) | 2017-05-16 | 2025-06-16 | 異型braf変異を有するがんを処置するための組成物および方法 |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022160828A Withdrawn JP2022176316A (ja) | 2017-05-16 | 2022-10-05 | 異型braf変異を有するがんを処置するための組成物および方法 |
| JP2025100020A Pending JP2025123379A (ja) | 2017-05-16 | 2025-06-16 | 異型braf変異を有するがんを処置するための組成物および方法 |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US12582635B2 (https=) |
| EP (1) | EP3624896A4 (https=) |
| JP (3) | JP7405408B2 (https=) |
| CN (2) | CN110799245B (https=) |
| AU (2) | AU2018269982B2 (https=) |
| CA (1) | CA3063614A1 (https=) |
| MX (1) | MX2019013634A (https=) |
| WO (1) | WO2018213302A1 (https=) |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2017329090B9 (en) | 2016-09-19 | 2019-09-05 | Novartis Ag | Therapeutic combinations comprising a RAF inhibitor and a ERK inhibitor |
| ES2952265T3 (es) | 2017-05-02 | 2023-10-30 | Novartis Ag | Terapia combinada que comprende un inhibidor de Raf y trametinib |
| US12398209B2 (en) | 2018-01-22 | 2025-08-26 | Janssen Biotech, Inc. | Methods of treating cancers with antagonistic anti-PD-1 antibodies |
| CN109771436A (zh) * | 2019-03-06 | 2019-05-21 | 康赋葆(深圳)生物医药科技有限公司 | 四氢姜黄素与卡培他滨联合治疗大肠癌的应用 |
| ES3025633T3 (en) | 2019-05-13 | 2025-06-09 | Novartis Ag | New crystalline forms of n-(3-(2-(2-hydroxyethoxy)-6-morpholinopyridin-4-yl)-4-methvlphenyl)-2(trifluoromethyl)isonicotinamide as raf inhibitors for the treatment of cancer |
| JP7234418B2 (ja) * | 2019-05-16 | 2023-03-07 | イーライ リリー アンド カンパニー | Brafv600e大腸癌の治療に使用するためのerk1/2阻害剤と、braf阻害剤およびegfr阻害剤との三重組み合わせ |
| MX2021014961A (es) | 2019-06-06 | 2022-01-24 | Hutchison Medipharma Ltd | Compuestos triciclicos y su uso. |
| GB201913124D0 (en) * | 2019-09-11 | 2019-10-23 | Seald As | Compositions and methods for treatment of cholangiocarcinoma |
| GB201913121D0 (en) * | 2019-09-11 | 2019-10-23 | Seald As | Compositions and methods for treatment of cholangiocarcinoma |
| GB201913123D0 (en) * | 2019-09-11 | 2019-10-23 | Seald As | Compositions and methods for treatment of cholangiocarcinoma |
| CN110538316B (zh) * | 2019-10-17 | 2021-10-15 | 滨州医学院 | 5-fu和胰高血糖素联合用于制备治疗结直肠癌的药物的用途和药物组合物 |
| JP7582694B2 (ja) | 2020-01-10 | 2024-11-13 | イミューニヤリング コーポレーション | Mek阻害剤及びその治療的使用 |
| EP4106756A1 (en) * | 2020-02-18 | 2022-12-28 | Novartis AG | Therapeutic combinations comprising a raf inhibitor for use in treating braf mutant nsclc |
| WO2022179568A1 (en) * | 2021-02-25 | 2022-09-01 | Westlake Therapeutics (Hangzhou) Co., Limited | Neoantigenic peptide and its use for treating braf gene mutation related diseases |
| JP2024509269A (ja) * | 2021-03-09 | 2024-02-29 | ジェネンテック, インコーポレイテッド | 脳がんの治療における使用のためのベルバラフェニブ |
| CN117677398A (zh) * | 2021-07-27 | 2024-03-08 | 东丽株式会社 | 用于癌的治疗和/或预防的药品 |
| WO2023049798A1 (en) * | 2021-09-22 | 2023-03-30 | Henry Ford Health System | Hdac3 inhibitors for the treatment of langerhans cell histiocytosis and langerhans cell sarcoma |
| CN116570599B (zh) * | 2023-07-04 | 2023-10-20 | 四川大学华西医院 | Vs6766联合ly3009120的应用及药物组合物 |
| CN121243179B (zh) * | 2025-12-05 | 2026-02-24 | 山东大学 | 盐酸帕唑帕尼在制备卵巢功能保护药物方面的应用 |
Family Cites Families (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2639416C (en) * | 2007-09-11 | 2019-12-31 | F. Hoffmann-La Roche Ag | Diagnostic test for susceptibility to b-raf kinase inhibitors |
| BR112015002285B1 (pt) | 2012-08-09 | 2022-05-10 | Celgene Corporation | Uso do composto 3-(4-((4-(morfolinometil)benzil)oxi)-1-oxoisoindolin-2-il)piperidina-2,6-diona para tratar ou gerenciar câncer |
| EP3626309B1 (en) | 2012-08-13 | 2023-03-08 | The Rockefeller University | Lxrbeta agonist for the treatment of cancer |
| UA118846C2 (uk) * | 2013-03-21 | 2019-03-25 | Новартіс Аг | Комбінована терапія |
| US10617723B2 (en) * | 2013-03-29 | 2020-04-14 | Biomed Valley Discoveries, Inc. | C. novyi for the treatment of solid tumors in humans |
| CN105530931B (zh) * | 2013-07-12 | 2019-11-08 | 皮拉马尔企业有限公司 | 用于治疗黑素瘤的药物组合 |
| WO2015095835A1 (en) * | 2013-12-20 | 2015-06-25 | Biomed Valley Discoveries, Inc. | Methods of modulating radioiodine uptake for the treatment of radioiodine-refractory cancers |
| JP6678583B2 (ja) * | 2013-12-20 | 2020-04-22 | バイオメッド バレー ディスカバリーズ,インコーポレイティド | 2型mek阻害剤およびerk阻害剤の組み合わせを用いるがん処置 |
| WO2015095842A2 (en) * | 2013-12-20 | 2015-06-25 | Biomed Valley Discoveries, Inc. | Methods and compositions for treating non-erk mapk pathway inhibitor-resistant cancers |
| JP6727127B2 (ja) * | 2013-12-20 | 2020-07-29 | バイオメッド バレー ディスカバリーズ,インコーポレイティド | Pi3k/aktシグナル経路阻害剤およびerk阻害剤の組み合わせを使用するがん処置 |
| US20160310477A1 (en) * | 2013-12-20 | 2016-10-27 | Biomed Valley Discoveries, Inc. | Cancer treatments using combinations of mek type 1 and erk inhibitors |
| AU2014368927B2 (en) * | 2013-12-20 | 2018-10-25 | Biomed Valley Discoveries, Inc. | Cancer treatments using combinations of CDK and ERK inhibitors |
| CA3240745A1 (en) * | 2013-12-20 | 2015-06-25 | Biomed Valley Discoveries, Inc. | Cancer treatment using combinations of erk and raf inhibitors |
| JP7036594B2 (ja) | 2014-07-14 | 2022-03-15 | ウニベルジテート チューリッヒ プロレクトラット エムエンベー | Braf陽性癌を患っている患者を、braf阻害剤に対する非レスポンダーであると及びmapk/erk阻害剤に対するレスポンダーであると同定する手段及び方法 |
| WO2016025650A1 (en) * | 2014-08-13 | 2016-02-18 | Celgene Avilomics Research, Inc. | Combinations of an erk inhibitor and a cdk4/6 inhibitor and related methods |
| WO2016205418A1 (en) * | 2015-06-15 | 2016-12-22 | Asana Biosciences, Llc | Heterocyclic inhibitors of erk1 and erk2 and their use in the treatment of cancer |
| EP3320093A4 (en) * | 2015-07-08 | 2019-01-30 | Dana-Farber Cancer Institute, Inc. | COMPOSITIONS AND METHODS FOR IDENTIFYING, EVALUATING, PREVENTING AND TREATING CANCER USING SLNCR ISOFORMS |
-
2018
- 2018-05-15 AU AU2018269982A patent/AU2018269982B2/en active Active
- 2018-05-15 MX MX2019013634A patent/MX2019013634A/es unknown
- 2018-05-15 EP EP18801345.2A patent/EP3624896A4/en active Pending
- 2018-05-15 WO PCT/US2018/032755 patent/WO2018213302A1/en not_active Ceased
- 2018-05-15 CN CN201880040655.8A patent/CN110799245B/zh active Active
- 2018-05-15 US US16/613,480 patent/US12582635B2/en active Active
- 2018-05-15 CN CN202210881186.0A patent/CN116036278B/zh active Active
- 2018-05-15 JP JP2019563125A patent/JP7405408B2/ja active Active
- 2018-05-15 CA CA3063614A patent/CA3063614A1/en active Pending
-
2022
- 2022-10-05 JP JP2022160828A patent/JP2022176316A/ja not_active Withdrawn
-
2024
- 2024-09-09 AU AU2024219529A patent/AU2024219529A1/en active Pending
-
2025
- 2025-06-16 JP JP2025100020A patent/JP2025123379A/ja active Pending
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2020519660A5 (https=) | ||
| JP7405408B2 (ja) | 異型braf変異を有するがんを処置するための組成物および方法 | |
| US11679112B2 (en) | Cancer treatments using combinations of CDK and ERK inhibitors | |
| Herrera et al. | Autologous stem-cell transplantation after second-line brentuximab vedotin in relapsed or refractory Hodgkin lymphoma | |
| Saad et al. | SRC kinase inhibition: targeting bone metastases and tumor growth in prostate and breast cancer | |
| Dong et al. | Histone deacetylase inhibitor potentiated the ability of MTOR inhibitor to induce autophagic cell death in Burkitt leukemia/lymphoma | |
| JP7788114B2 (ja) | ヒトにおける固形腫瘍の処置のためのC.novyi | |
| JP2017502017A5 (https=) | ||
| NZ592039A (en) | Combination therapy for the treatment of ocular neovascular disorders | |
| Han et al. | In vitro and in vivo activity of sacituzumab govitecan, an antibody-drug conjugate targeting trophoblast cell-surface antigen 2 (Trop-2) in uterine serous carcinoma | |
| RU2016129287A (ru) | Лечение злокачественных опухолей с применением комбинаций ингибиторов erk и raf | |
| Spigel et al. | Efficacy and safety of oral topotecan and bevacizumab combination as second-line treatment for relapsed small-cell lung cancer: an open-label multicenter single-arm phase II study | |
| JP2017500320A5 (https=) | ||
| CN101743013A (zh) | 使用整联蛋白配体治疗癌的特异疗法和药物 | |
| WO2015095831A1 (en) | Cancer treatments using combinations of mtor and erk inhibitors | |
| Rocchi et al. | The angiogenic asset of soft tissue sarcomas: a new tool to discover new therapeutic targets | |
| Miller et al. | Combination treatment options for castration-resistant prostate cancer | |
| Kochar et al. | Contemporary updates on clinical trials of antiangiogenic agents in the treatment of glioblastoma multiforme | |
| WO2014160967A9 (en) | C. novyi for the treatment of solid tumors in non-human animals | |
| Higano | New treatment options for patients with metastatic castration-resistant prostate cancer | |
| CA3118690A1 (en) | Use of tivozanib to treat subjects with refractory cancer | |
| RU2024101803A (ru) | Композиции и способы для лечения злокачественной опухоли с атипичными мутациями braf | |
| US20220096436A1 (en) | Combination product for the treatment of cancer | |
| HK40086947A (zh) | 用於治疗具有非典型braf突变的癌症的组合物和方法 | |
| HK40086947B (zh) | 用於治疗具有非典型braf突变的癌症的组合物和方法 |