JP2020515864A5 - - Google Patents
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- Publication number
- JP2020515864A5 JP2020515864A5 JP2019554648A JP2019554648A JP2020515864A5 JP 2020515864 A5 JP2020515864 A5 JP 2020515864A5 JP 2019554648 A JP2019554648 A JP 2019554648A JP 2019554648 A JP2019554648 A JP 2019554648A JP 2020515864 A5 JP2020515864 A5 JP 2020515864A5
- Authority
- JP
- Japan
- Prior art keywords
- chamber
- analyte
- fluid
- microfluidic
- chambers
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000012530 fluid Substances 0.000 claims description 14
- 238000000034 method Methods 0.000 claims description 14
- 244000052769 pathogen Species 0.000 claims description 13
- 239000000758 substrate Substances 0.000 claims description 12
- 239000008280 blood Substances 0.000 claims description 11
- 210000004369 blood Anatomy 0.000 claims description 11
- 238000001514 detection method Methods 0.000 claims description 11
- 230000001717 pathogenic effect Effects 0.000 claims description 10
- 238000004140 cleaning Methods 0.000 claims description 9
- 230000008569 process Effects 0.000 claims description 8
- 230000004044 response Effects 0.000 claims description 7
- 239000007788 liquid Substances 0.000 claims description 6
- 239000008151 electrolyte solution Substances 0.000 claims description 5
- 230000008859 change Effects 0.000 claims description 3
- 241000894006 Bacteria Species 0.000 claims description 2
- 239000000243 solution Substances 0.000 claims description 2
- 239000012491 analyte Substances 0.000 claims 15
- 210000004027 cell Anatomy 0.000 claims 7
- 239000002516 radical scavenger Substances 0.000 claims 6
- 102000039446 nucleic acids Human genes 0.000 claims 2
- 108020004707 nucleic acids Proteins 0.000 claims 2
- 150000007523 nucleic acids Chemical class 0.000 claims 2
- 108090000623 proteins and genes Proteins 0.000 claims 2
- 102000004169 proteins and genes Human genes 0.000 claims 2
- 108010031480 Artificial Receptors Proteins 0.000 claims 1
- 241000192125 Firmicutes Species 0.000 claims 1
- 241000233866 Fungi Species 0.000 claims 1
- 206010028980 Neoplasm Diseases 0.000 claims 1
- 230000000903 blocking effect Effects 0.000 claims 1
- 201000011510 cancer Diseases 0.000 claims 1
- 210000001175 cerebrospinal fluid Anatomy 0.000 claims 1
- 238000005234 chemical deposition Methods 0.000 claims 1
- 239000003795 chemical substances by application Substances 0.000 claims 1
- 230000005495 cold plasma Effects 0.000 claims 1
- 238000000151 deposition Methods 0.000 claims 1
- 230000008021 deposition Effects 0.000 claims 1
- 210000001808 exosome Anatomy 0.000 claims 1
- 210000003722 extracellular fluid Anatomy 0.000 claims 1
- 230000003100 immobilizing effect Effects 0.000 claims 1
- 239000003550 marker Substances 0.000 claims 1
- 239000003147 molecular marker Substances 0.000 claims 1
- 210000002381 plasma Anatomy 0.000 claims 1
- 150000003384 small molecules Chemical class 0.000 claims 1
- 210000004243 sweat Anatomy 0.000 claims 1
- 230000008685 targeting Effects 0.000 claims 1
- 210000002700 urine Anatomy 0.000 claims 1
- 238000011534 incubation Methods 0.000 description 8
- 239000002699 waste material Substances 0.000 description 7
- 239000004205 dimethyl polysiloxane Substances 0.000 description 6
- 238000000206 photolithography Methods 0.000 description 6
- 229920000435 poly(dimethylsiloxane) Polymers 0.000 description 6
- 108091003079 Bovine Serum Albumin Proteins 0.000 description 4
- 230000001580 bacterial effect Effects 0.000 description 4
- 229940098773 bovine serum albumin Drugs 0.000 description 4
- 238000007689 inspection Methods 0.000 description 4
- 239000011534 wash buffer Substances 0.000 description 4
- 238000010586 diagram Methods 0.000 description 3
- LOKCTEFSRHRXRJ-UHFFFAOYSA-I dipotassium trisodium dihydrogen phosphate hydrogen phosphate dichloride Chemical compound P(=O)(O)(O)[O-].[K+].P(=O)(O)([O-])[O-].[Na+].[Na+].[Cl-].[K+].[Cl-].[Na+] LOKCTEFSRHRXRJ-UHFFFAOYSA-I 0.000 description 3
- 238000001453 impedance spectrum Methods 0.000 description 3
- 238000004519 manufacturing process Methods 0.000 description 3
- 239000002953 phosphate buffered saline Substances 0.000 description 3
- 239000011148 porous material Substances 0.000 description 3
- 238000000926 separation method Methods 0.000 description 3
- 239000003792 electrolyte Substances 0.000 description 2
- 230000005284 excitation Effects 0.000 description 2
- PCHJSUWPFVWCPO-UHFFFAOYSA-N gold Chemical compound [Au] PCHJSUWPFVWCPO-UHFFFAOYSA-N 0.000 description 2
- 239000010931 gold Substances 0.000 description 2
- 229910052737 gold Inorganic materials 0.000 description 2
- 238000007654 immersion Methods 0.000 description 2
- 230000007246 mechanism Effects 0.000 description 2
- 229920002120 photoresistant polymer Polymers 0.000 description 2
- 238000001878 scanning electron micrograph Methods 0.000 description 2
- 241000191967 Staphylococcus aureus Species 0.000 description 1
- 230000009471 action Effects 0.000 description 1
- 238000003491 array Methods 0.000 description 1
- 239000003153 chemical reaction reagent Substances 0.000 description 1
- 230000008878 coupling Effects 0.000 description 1
- 238000010168 coupling process Methods 0.000 description 1
- 238000005859 coupling reaction Methods 0.000 description 1
- 239000011521 glass Substances 0.000 description 1
- 238000001459 lithography Methods 0.000 description 1
- 238000000054 nanosphere lithography Methods 0.000 description 1
- -1 polydimethylsiloxane Polymers 0.000 description 1
- 238000001179 sorption measurement Methods 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB1705328.1 | 2017-04-03 | ||
| GB1705328.1A GB2561173A (en) | 2017-04-03 | 2017-04-03 | Microfluidic device for detection of analytes |
| PCT/EP2018/057997 WO2018184957A1 (en) | 2017-04-03 | 2018-03-28 | Microfluidic device for detection of analytes |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2020515864A JP2020515864A (ja) | 2020-05-28 |
| JP2020515864A5 true JP2020515864A5 (enExample) | 2021-05-06 |
| JP7202664B2 JP7202664B2 (ja) | 2023-01-12 |
Family
ID=58682739
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019554648A Active JP7202664B2 (ja) | 2017-04-03 | 2018-03-28 | 分析物検出用の微少流体装置 |
Country Status (9)
| Country | Link |
|---|---|
| US (2) | US11406976B2 (enExample) |
| EP (1) | EP3606667B1 (enExample) |
| JP (1) | JP7202664B2 (enExample) |
| AU (2) | AU2018247760B2 (enExample) |
| CA (1) | CA3058081C (enExample) |
| ES (1) | ES2992414T3 (enExample) |
| GB (1) | GB2561173A (enExample) |
| PL (1) | PL3606667T3 (enExample) |
| WO (1) | WO2018184957A1 (enExample) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US11731132B2 (en) * | 2017-12-19 | 2023-08-22 | Biological Dynamics, Inc. | Methods and devices for detection of multiple analytes from a biological sample |
| WO2020223900A1 (en) * | 2019-05-07 | 2020-11-12 | Boe Technology Group Co., Ltd. | Method of classifying and counting cells in a sample, bioassay kit, and micropore array plate |
| CN122249285A (zh) * | 2023-10-19 | 2026-06-19 | 维塔生物科技公司 | 用于对生物样本的光学分析的设备、系统和方法 |
Family Cites Families (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0938674B1 (de) * | 1996-11-16 | 2005-06-01 | NMI Naturwissenschaftliches und Medizinisches Institut an der Universität Tübingen in Reutlingen Stiftung Bürgerlichen Rechts | Mikroelementenanordnung, verfahren zum kontaktieren von in einer flüssigen umgebung befindlichen zellen und verfahren zum herstellen einer mikroelementenanordnung |
| US5922604A (en) * | 1997-06-05 | 1999-07-13 | Gene Tec Corporation | Thin reaction chambers for containing and handling liquid microvolumes |
| FR2787582B1 (fr) * | 1998-12-16 | 2001-01-12 | Commissariat Energie Atomique | Procede de fabrication d'une biopuce et biopuce |
| US20060068409A1 (en) * | 2000-11-27 | 2006-03-30 | Phan Brigitte C | Use of restriction enzymes and other chemical methods to decrease non-specific binding in dual bead assays and related bio-discs, methods, and system apparatus for detecting medical targets |
| CA2468245A1 (en) | 2001-11-27 | 2003-06-05 | Burstein Technologies, Inc. | Magneto-optical bio-discs and systems including related methods |
| GB0311902D0 (en) | 2003-05-22 | 2003-06-25 | Cambridge Life Sciences | Assay method and apparatus |
| EP1899702A2 (de) | 2005-04-09 | 2008-03-19 | Boehringer Ingelheim microParts GmbH | Vorrichtung und verfahren zur untersuchung einer probenflüssigkeit |
| EP1885883A4 (en) | 2005-04-30 | 2009-09-23 | Jae Chern Yoo | BIO DISC, BIOT DRIVER DEVICE AND TEST METHOD USING THEREOF |
| CN101389956B (zh) | 2005-12-21 | 2013-01-02 | 三星电子株式会社 | 生物存储盘及其驱动装置和采用其驱动装置的分析方法 |
| US7652768B2 (en) * | 2006-12-01 | 2010-01-26 | Canon Kabushiki Kaisha | Chemical sensing apparatus and chemical sensing method |
| JP2008157923A (ja) | 2006-12-01 | 2008-07-10 | Canon Inc | 化学センシング装置及び化学センシング方法 |
| KR100913148B1 (ko) * | 2007-04-10 | 2009-08-19 | 이금필 | 자성입자를 포함하는 자기력 기반 바이오 센서 |
| KR101335726B1 (ko) | 2007-06-04 | 2013-12-04 | 삼성전자주식회사 | 면역혈청 검사 및 생화학 검사를 동시에 수행하는 디스크형미세유동장치 |
| EP2201374B1 (en) * | 2007-08-30 | 2015-10-07 | Trustees Of Tufts College | Methods for determining the concentration of an analyte in solution. |
| US20110192726A1 (en) * | 2008-10-31 | 2011-08-11 | Agency For Science ,Technology And Research | Device and method for detection of analyte from a sample |
| JP2011232328A (ja) | 2010-04-09 | 2011-11-17 | Hitachi Ltd | 生体物質検出アレイ、計測装置および計測方法 |
| CA2862630A1 (en) * | 2012-01-27 | 2013-08-01 | University Of Tennessee Research Foundation | Method and apparatus for detection of a biomarker by alternating current electrokinetics |
| JP2013220066A (ja) | 2012-04-17 | 2013-10-28 | Hitachi Ltd | センサチップ及びそれを用いた測定方法 |
| GB2515490A (en) * | 2013-06-24 | 2014-12-31 | Univ Dublin City | An aperture array substrate device, a detection system and a method for detecting analytes in a sample |
| WO2015187792A1 (en) * | 2014-06-05 | 2015-12-10 | President And Fellows Of Harvard College | Protein analysis assay system |
| US10274492B2 (en) | 2015-04-10 | 2019-04-30 | The Curators Of The University Of Missouri | High sensitivity impedance sensor |
| CN108449996A (zh) | 2015-08-07 | 2018-08-24 | Poc医疗系统有限公司 | 微流体装置及其使用方法 |
| US20170010259A1 (en) * | 2016-06-12 | 2017-01-12 | Ghassem Amoabediny | Multiplexed microfluidic proteomic platform |
-
2017
- 2017-04-03 GB GB1705328.1A patent/GB2561173A/en not_active Withdrawn
-
2018
- 2018-03-28 US US16/500,190 patent/US11406976B2/en active Active
- 2018-03-28 EP EP18714243.5A patent/EP3606667B1/en active Active
- 2018-03-28 AU AU2018247760A patent/AU2018247760B2/en active Active
- 2018-03-28 WO PCT/EP2018/057997 patent/WO2018184957A1/en not_active Ceased
- 2018-03-28 CA CA3058081A patent/CA3058081C/en active Active
- 2018-03-28 PL PL18714243.5T patent/PL3606667T3/pl unknown
- 2018-03-28 ES ES18714243T patent/ES2992414T3/es active Active
- 2018-03-28 JP JP2019554648A patent/JP7202664B2/ja active Active
-
2022
- 2022-07-05 US US17/857,824 patent/US11850588B2/en active Active
- 2022-12-06 AU AU2022283663A patent/AU2022283663B2/en active Active
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