JP2020513794A - 多能性幹細胞および造血始原細胞からのヒトミクログリア様細胞の分化と使用 - Google Patents

多能性幹細胞および造血始原細胞からのヒトミクログリア様細胞の分化と使用 Download PDF

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JP2020513794A
JP2020513794A JP2019546831A JP2019546831A JP2020513794A JP 2020513794 A JP2020513794 A JP 2020513794A JP 2019546831 A JP2019546831 A JP 2019546831A JP 2019546831 A JP2019546831 A JP 2019546831A JP 2020513794 A JP2020513794 A JP 2020513794A
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マシュー・ブラートン−ジョーンズ
エドセル・アブド
ウェイン・プーン
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University of California
University of California Berkeley
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JP2019546831A 2017-02-28 2018-02-26 多能性幹細胞および造血始原細胞からのヒトミクログリア様細胞の分化と使用 Withdrawn JP2020513794A (ja)

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JP2023020284A JP7668551B2 (ja) 2017-02-28 2023-02-13 多能性幹細胞および造血始原細胞からのヒトミクログリア様細胞の分化と使用
JP2023144942A JP2023182587A (ja) 2017-02-28 2023-09-07 多能性幹細胞および造血始原細胞からのヒトミクログリア様細胞の分化と使用

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US201762464925P 2017-02-28 2017-02-28
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PCT/US2018/019763 WO2018160496A1 (en) 2017-02-28 2018-02-26 Differentiation and use of human microglia-like cells from pluripotent stem cells and hematopoietic progenitors

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JP2023020284A Active JP7668551B2 (ja) 2017-02-28 2023-02-13 多能性幹細胞および造血始原細胞からのヒトミクログリア様細胞の分化と使用
JP2023144942A Pending JP2023182587A (ja) 2017-02-28 2023-09-07 多能性幹細胞および造血始原細胞からのヒトミクログリア様細胞の分化と使用

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JP2023144942A Pending JP2023182587A (ja) 2017-02-28 2023-09-07 多能性幹細胞および造血始原細胞からのヒトミクログリア様細胞の分化と使用

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JP2023511004A (ja) * 2019-12-17 2023-03-16 コアステム カンパニー リミテッド ヒト多能性幹細胞由来の３ｄオルガノイドを使用して大量のミクログリアを確保する、ミクログリアの分化のための方法
US12421517B2 (en) 2021-04-01 2025-09-23 The Regents Of The University Of California Genetic modification of mammalian cells to confer resistance to CSF1R antagonists

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GB201619876D0 (en) 2016-11-24 2017-01-11 Cambridge Entpr Ltd Controllable transcription
JOP20190248A1 (ar) 2017-04-21 2019-10-20 Amgen Inc بروتينات ربط مولد ضد trem2 واستخداماته
EP3856765A4 (en) * 2018-09-28 2022-10-05 Memorial Sloan Kettering Cancer Center STEM CELL-DERIVED HUMAN MICROGLIACELLS, PROCESS FOR THEIR PRODUCTION AND THEIR USE
CN113924362B (zh) * 2019-03-29 2025-03-07 新加坡科技研究局 小胶质细胞充足的脑类器官
US20220235322A1 (en) * 2019-05-30 2022-07-28 President And Fellows Of Harvard College Reproducible brain organoids and methods of making
GB2584664B (en) * 2019-06-10 2023-05-24 Newcells Biotech Ltd Improved retinal organoids and methods of making the same
CN110205295B (zh) * 2019-06-25 2021-10-29 中国科学院动物研究所 一种多能干细胞诱导产生小胶质细胞的方法及试剂盒
CN112011509A (zh) * 2020-09-25 2020-12-01 南京中医药大学 脊髓损伤大鼠原代小胶质细胞分离方法及应用
CN114426951B (zh) * 2020-10-29 2024-05-14 北京赛尔湃腾科技咨询合伙企业(有限合伙) 利用多能干细胞制备小胶质细胞样细胞的方法
WO2024015933A2 (en) * 2022-07-13 2024-01-18 The Regents Of The University Of California Transplanting stem cell-derived microglia to treat leukodystrophies
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