JP2020513041A - 病原体の阻害および／または粘液の改変のための化合物、組成物、および方法 - Google Patents

病原体の阻害および／または粘液の改変のための化合物、組成物、および方法 Download PDF

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Publication number
JP2020513041A
JP2020513041A JP2020504468A JP2020504468A JP2020513041A JP 2020513041 A JP2020513041 A JP 2020513041A JP 2020504468 A JP2020504468 A JP 2020504468A JP 2020504468 A JP2020504468 A JP 2020504468A JP 2020513041 A JP2020513041 A JP 2020513041A
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Japan
Prior art keywords
mucus
releasing
biopolymer
releasing biopolymer
subject
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Pending
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JP2020504468A
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English (en)
Japanese (ja)
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JP2020513041A5 (enExample
Inventor
エイチ． シェーンフィッシュ，マーク
エイチ． シェーンフィッシュ，マーク
レイガード，ケイトリン
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University of North Carolina at Chapel Hill
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University of North Carolina at Chapel Hill
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Application filed by University of North Carolina at Chapel Hill filed Critical University of North Carolina at Chapel Hill
Publication of JP2020513041A publication Critical patent/JP2020513041A/ja
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/74—Synthetic polymeric materials
    • A61K31/785—Polymers containing nitrogen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0065—Forms with gastric retention, e.g. floating on gastric juice, adhering to gastric mucosa, expanding to prevent passage through the pylorus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
JP2020504468A 2017-04-10 2018-04-10 病原体の阻害および／または粘液の改変のための化合物、組成物、および方法 Pending JP2020513041A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201762483655P 2017-04-10 2017-04-10
US62/483,655 2017-04-10
PCT/IB2018/052522 WO2018189687A1 (en) 2017-04-10 2018-04-10 Compounds, compositions and methods for inhibiting a pathogen and/or modifying mucus

Publications (2)

Publication Number Publication Date
JP2020513041A true JP2020513041A (ja) 2020-04-30
JP2020513041A5 JP2020513041A5 (enExample) 2021-05-20

Family

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Family Applications (1)

Application Number Title Priority Date Filing Date
JP2020504468A Pending JP2020513041A (ja) 2017-04-10 2018-04-10 病原体の阻害および／または粘液の改変のための化合物、組成物、および方法

Country Status (5)

Country Link
US (1) US11324773B2 (enExample)
EP (1) EP3592335A4 (enExample)
JP (1) JP2020513041A (enExample)
CN (1) CN110573143A (enExample)
WO (1) WO2018189687A1 (enExample)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11534382B2 (en) 2017-06-19 2022-12-27 Novan, Inc. Topical compositions and methods of using the same
US11285171B2 (en) 2018-03-01 2022-03-29 Novan, Inc. Nitric oxide releasing suppositories and methods of use thereof
CA3132400C (en) 2019-03-18 2026-05-12 Cedars-Sinai Medical Center Compositions and methods to treat gastrointestinal diseases and disorders
CN115486478A (zh) * 2022-10-09 2022-12-20 江苏天美健大自然生物工程有限公司 一种蛋白饮料用防腐剂组合物及其制备方法
CN122477047A (zh) * 2023-08-28 2026-07-28 卡尔罗伊健康科学有限责任公司 保护和增强肠糖萼结构与功能完整性的组合物及方法

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5234933A (en) 1991-10-31 1993-08-10 Board Of Governors Of Wayne State University And Vanderbilt University Cyclic hydroxamic acids
DE4210332C1 (enExample) 1992-03-30 1993-07-15 Gruenenthal Gmbh, 5100 Aachen, De
US5238832A (en) 1992-06-08 1993-08-24 Board Of Governors Of Wayne State University Aryl aliphatic acids
US5859058A (en) * 1994-07-14 1999-01-12 Glaxo Wellcome Inc. Nitric oxide synthase inhibitors for inhibiting the production of airway mucas
US6180082B1 (en) 1997-11-24 2001-01-30 Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College Method to enhance tissue accumulation of radiolabeled compounds
US6261594B1 (en) 1998-11-25 2001-07-17 The University Of Akron Chitosan-based nitric oxide donor compositions
IT1303793B1 (it) * 1998-11-27 2001-02-23 Promefarm S R L "composizione farmaceutica comprendente un composto organico donatoredi ossido nitrico (no)"
AU2005244079A1 (en) * 2004-05-11 2005-11-24 Pulmonox Technologies Corporation The use of inhaled gaseous nitric oxide as a mucolytic agent or expectorant
WO2009049208A1 (en) * 2007-10-12 2009-04-16 The University Of North Carolina At Chapel Hill Use of nitric oxide to enhance the efficacy of silver and other topical wound care agents
GB201021186D0 (en) * 2010-12-14 2011-01-26 Novabiotics Ltd Composition
CN106986952B (zh) * 2012-08-17 2020-03-10 北卡罗来纳大学查珀尔希尔分校 水溶性的释放一氧化氮的聚葡糖胺和其用途

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
BIOFOULING, vol. 31, JPN6022013272, 2015, ISSN: 0004843318 *

Also Published As

Publication number Publication date
EP3592335A1 (en) 2020-01-15
US11324773B2 (en) 2022-05-10
WO2018189687A1 (en) 2018-10-18
US20200085858A1 (en) 2020-03-19
CN110573143A (zh) 2019-12-13
EP3592335A4 (en) 2021-01-27

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