JP2020502137A5 - - Google Patents
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- Publication number
- JP2020502137A5 JP2020502137A5 JP2019531817A JP2019531817A JP2020502137A5 JP 2020502137 A5 JP2020502137 A5 JP 2020502137A5 JP 2019531817 A JP2019531817 A JP 2019531817A JP 2019531817 A JP2019531817 A JP 2019531817A JP 2020502137 A5 JP2020502137 A5 JP 2020502137A5
- Authority
- JP
- Japan
- Prior art keywords
- tremor
- syndrome
- pharmaceutical composition
- formula
- use according
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 206010044565 Tremor Diseases 0.000 claims 79
- 208000011580 syndromic disease Diseases 0.000 claims 30
- 239000008194 pharmaceutical composition Substances 0.000 claims 13
- 239000003795 chemical substances by application Substances 0.000 claims 8
- -1 carbamate compound Chemical class 0.000 claims 7
- 208000007101 Muscle Cramp Diseases 0.000 claims 6
- 206010072377 Psychogenic tremor Diseases 0.000 claims 6
- 208000005392 Spasm Diseases 0.000 claims 6
- 125000000217 alkyl group Chemical group 0.000 claims 6
- 230000002490 cerebral effect Effects 0.000 claims 6
- 201000006517 essential tremor Diseases 0.000 claims 6
- 229910052736 halogen Inorganic materials 0.000 claims 6
- 150000002367 halogens Chemical class 0.000 claims 6
- 239000001257 hydrogen Substances 0.000 claims 6
- 150000002431 hydrogen Chemical class 0.000 claims 6
- 229910052739 hydrogen Inorganic materials 0.000 claims 6
- 230000002981 neuropathic effect Effects 0.000 claims 6
- 241000124008 Mammalia Species 0.000 claims 4
- 206010071390 Resting tremor Diseases 0.000 claims 4
- 239000003814 drug Substances 0.000 claims 4
- 229940079593 drug Drugs 0.000 claims 4
- 125000006731 (C1-C8) thioalkoxy group Chemical group 0.000 claims 3
- 125000004182 2-chlorophenyl group Chemical group [H]C1=C([H])C(Cl)=C(*)C([H])=C1[H] 0.000 claims 3
- 206010073211 Postural tremor Diseases 0.000 claims 3
- 125000003545 alkoxy group Chemical group 0.000 claims 3
- KXDHJXZQYSOELW-UHFFFAOYSA-N carbonic acid monoamide Natural products NC(O)=O KXDHJXZQYSOELW-UHFFFAOYSA-N 0.000 claims 3
- 125000004494 ethyl ester group Chemical group 0.000 claims 3
- 125000001188 haloalkyl group Chemical group 0.000 claims 3
- 230000002265 prevention Effects 0.000 claims 3
- 208000002343 primary orthostatic tremor Diseases 0.000 claims 3
- 150000003839 salts Chemical class 0.000 claims 3
- 210000001584 soft palate Anatomy 0.000 claims 3
- 239000012453 solvate Substances 0.000 claims 3
- KJAMZCVTJDTESW-UHFFFAOYSA-N tiracizine Chemical compound C1CC2=CC=CC=C2N(C(=O)CN(C)C)C2=CC(NC(=O)OCC)=CC=C21 KJAMZCVTJDTESW-UHFFFAOYSA-N 0.000 claims 3
- 208000014094 Dystonic disease Diseases 0.000 claims 2
- 208000010118 dystonia Diseases 0.000 claims 2
- 230000035479 physiological effects, processes and functions Effects 0.000 claims 2
- 206010069099 Holmes tremor Diseases 0.000 claims 1
- 239000003937 drug carrier Substances 0.000 claims 1
- 150000004677 hydrates Chemical class 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
- 230000001225 therapeutic effect Effects 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| KR20160170225 | 2016-12-14 | ||
| KR10-2016-0170225 | 2016-12-14 | ||
| PCT/KR2017/014743 WO2018111009A1 (ko) | 2016-12-14 | 2017-12-14 | 진전 또는 진전 증후군의 예방, 경감 또는 치료를 위한 카바메이트 화합물의 용도 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2020502137A JP2020502137A (ja) | 2020-01-23 |
| JP2020502137A5 true JP2020502137A5 (https=) | 2021-01-14 |
| JP7086076B2 JP7086076B2 (ja) | 2022-06-17 |
Family
ID=62558966
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019531817A Active JP7086076B2 (ja) | 2016-12-14 | 2017-12-14 | 振戦又は振戦症候群の予防、軽減又は治療のためのカルバメート化合物の使用 |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US11033531B2 (https=) |
| EP (1) | EP3556364B1 (https=) |
| JP (1) | JP7086076B2 (https=) |
| KR (1) | KR102635941B1 (https=) |
| CN (1) | CN110267657B (https=) |
| AU (1) | AU2017374459B2 (https=) |
| CL (1) | CL2019001623A1 (https=) |
| ES (1) | ES3039979T3 (https=) |
| IL (1) | IL267191B2 (https=) |
| MX (1) | MX391363B (https=) |
| MY (1) | MY198417A (https=) |
| WO (1) | WO2018111009A1 (https=) |
| ZA (1) | ZA201903749B (https=) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3711760B1 (en) * | 2017-11-14 | 2024-02-14 | SK Biopharmaceuticals Co., Ltd. | Use of carbamate compound for preventing or treating diseases associated with increase in late sodium current |
| ES2978226T3 (es) * | 2018-09-21 | 2024-09-09 | Sk Biopharmaceuticals Co Ltd | Compuesto de carbamato y uso de la formulación que lo comprende para prevenir, aliviar o tratar el trastorno de estrés agudo o el trastorno de estrés postraumático |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PT1411917E (pt) | 2001-02-27 | 2007-09-17 | Ortho Mcneil Pharm Inc | ''compostos carbamatos para utilização na prevenção ou tratamento de distúrbios do movimento'' |
| CN1938031A (zh) * | 2004-03-29 | 2007-03-28 | 默克公司 | 作为钠通道阻滞剂的联芳取代的吡嗪酮类 |
| US7598279B2 (en) * | 2005-04-22 | 2009-10-06 | Sk Holdings Co., Ltd. | Neurotherapeutic azole compounds |
| WO2008107909A1 (en) * | 2007-03-05 | 2008-09-12 | Indus Biotech Private Limited | Pharmaceutical compositions comprising trigonelline and 4-hydroxyisoleucine and a process thereof |
| WO2010150946A1 (en) | 2009-06-22 | 2010-12-29 | Sk Holdings Co., Ltd. | Method for preparation of carbamic acid (r)-1-aryl-2-tetrazolyl-ethyl ester |
| US8404461B2 (en) | 2009-10-15 | 2013-03-26 | SK Biopharmaceutical Co. Ltd. | Method for preparation of carbamic acid (R)-1-aryl-2-tetrazolyl-ethyl ester |
| CN109939092B (zh) | 2013-03-12 | 2022-03-22 | 比皮艾思药物研发有限公司 | 用于预防或治疗小儿癫痫和癫痫相关综合征的苯基氨基甲酸酯化合物 |
| KR102489052B1 (ko) | 2016-05-19 | 2023-01-16 | 에스케이바이오팜 주식회사 | 섬유근육통 또는 섬유근육통의 연관된 기능적 증후군을 예방 또는 치료하기 위한 카바메이트 화합물의 용도 |
-
2017
- 2017-12-14 US US16/468,936 patent/US11033531B2/en active Active
- 2017-12-14 KR KR1020197018409A patent/KR102635941B1/ko active Active
- 2017-12-14 JP JP2019531817A patent/JP7086076B2/ja active Active
- 2017-12-14 CN CN201780077642.3A patent/CN110267657B/zh active Active
- 2017-12-14 ES ES17880232T patent/ES3039979T3/es active Active
- 2017-12-14 EP EP17880232.8A patent/EP3556364B1/en active Active
- 2017-12-14 MX MX2019006941A patent/MX391363B/es unknown
- 2017-12-14 WO PCT/KR2017/014743 patent/WO2018111009A1/ko not_active Ceased
- 2017-12-14 AU AU2017374459A patent/AU2017374459B2/en active Active
- 2017-12-14 MY MYPI2019003351A patent/MY198417A/en unknown
-
2019
- 2019-06-10 IL IL267191A patent/IL267191B2/en unknown
- 2019-06-11 ZA ZA2019/03749A patent/ZA201903749B/en unknown
- 2019-06-12 CL CL2019001623A patent/CL2019001623A1/es unknown
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