JP2020168348A - Inspecting seal - Google Patents

Abstract

To provide an inspecting seal that is facilitated when being attached to an inspection object.SOLUTION: An inspecting seal 10 is used for imaging diagnosis using a micro wave. The inspecting seal includes a base film 11 having a coordinate grid 12 and attached to an inspection object. The base film 11 has a tensile breaking elongation of 130% or more and a 100% elongation tensile strength of 4 N/cm or less.SELECTED DRAWING: Figure 1

Description

The present invention relates to an inspection seal used for diagnostic imaging using microwaves.

Mammography using microwaves has been proposed as a method for inspecting breast cancer (see, for example, Patent Document 1). Mammography using microwaves does not require compression of the breast to be examined, so the subject does not feel pain during the examination. In addition, since X-rays are not used in mammography using microwaves, the subject is not exposed to radiation.

In microwave mammography, a probe scans the entire breast. At this time, a tattoo sticker on which the coordinate grid is printed is attached to the breast so that scan omission does not occur. The tattoo sticker includes an adhesive layer and an image receiving layer (see, for example, Patent Documents 2 and 3). A coordinate grid is formed on the image receiving layer by using an inkjet printer or the like.

International Publication No. 2017/057524 Japanese Unexamined Patent Publication No. 2006-1330865 Japanese Unexamined Patent Publication No. 2000-160111

By the way, since the tattoo sticker is easily torn, if the tattoo sticker has wrinkles when it is attached to the inspection target, it is difficult to remove the tattoo sticker once and then attach it again in order to remove the wrinkles. In particular, in order to attach the tattoo sticker to the entire breast, the area of the tattoo sticker becomes large, so that the tattoo sticker is more likely to be wrinkled. It should be noted that these matters are common not only when the examination target is the breast but also when it is another part in the human body.

An object of the present invention is to provide an inspection sticker that can be easily attached to an inspection target.

The inspection sticker for solving the above-mentioned problems is an inspection sticker used for image diagnosis using microwaves. It has a base film that has a scan index and can be attached to the inspection target. In the base film, the tensile elongation at break is 130% or more, and the 100% tensile tensile strength is 4 N / cm or less.

According to the above configuration, the inspection seal has a tensile elongation at break suitable for sticking to an inspection target and a 100% tensile tensile strength. Therefore, according to the inspection sticker, it is easy to attach it to the inspection target.

In the inspection seal, the fluidized bed is composed of an aliphatic hydrocarbon that allows microwaves to pass through more than water, and has a viscosity that allows the base film to be attached to the inspection target. The fluidized bed laminated with the above may be further provided.

According to the above configuration, the step of applying the chemical for attaching the base film to the inspection target to the inspection target can be omitted, so that the base film can be more easily attached to the inspection target.

In the inspection seal, the shear viscosity of the fluidized bed at 30 ° C. is JIS.
The shear viscosity defined in Z 8803: 2011 may be 1000 mPa · s or more and 200,000 mPa · s or less.

According to the above configuration, when the shear viscosity is 1000 mPa · s or more, the certainty that the fluidized bed attaches the base film to the inspection target can be increased. On the other hand, when the shear viscosity is 200,000 mPa · s or less, wrinkles and sagging are suppressed in the base film when the fluidized bed is formed on the base film by coating.

In the inspection seal, the fluidized bed may be formed from at least one selected from the group consisting of paraffin, squalane, and selecin. According to the above configuration, the fluidized bed can reliably transmit microwaves and reduce the irritation to the skin of the subject.

The inspection seal further includes an adhesive layer laminated on the base film, and the thickness of the adhesive layer is 5 μm or more and 25 μm or less. In the inspection seal, the base film and the adhesive layer are laminated. in the body, the moisture permeability as defined in JIS Z 0208 is, at 40 ° C. and 90% relative humidity conditions, it may be 750g ^/ m 2 · day or more. According to this configuration, when the moisture permeability of the inspection sticker satisfies the above range, sweating in the inspection target can be suppressed when the inspection sticker is attached to the inspection target.

The inspection sticker for solving the above-mentioned problems is an inspection sticker used for image diagnosis using microwaves. The base film having an index for guiding the position of the scan in the inspection target, and the adhesive layer laminated on the base film and having a thickness of 5 μm or more and 25 μm or less are provided. In the inspection seal, the tensile elongation at break specified in JIS K 7127 or more and the 100% elongation tensile stress are 10 MPa in the laminate of the base film and the adhesive layer.

According to the above configuration, the inspection seal has a tensile elongation at break suitable for sticking to an inspection target and a 100% elongation tensile stress. Therefore, according to the inspection sticker, it is easy to attach it to the inspection target.

In the above inspection seal, the moisture permeability specified in JIS Z 0208 may be 750 g / m ² · day or more under the conditions of 40 ° C. and 90% relative humidity. According to this configuration, when the moisture permeability of the inspection sticker satisfies the above range, sweating in the inspection target can be suppressed when the inspection sticker is attached to the inspection target.

In the inspection seal, the base film has a pair of surfaces facing each other, one of the pair of surfaces is a guide surface on which the index is printed, and the adhesive layer covers the guide surface. You may.

According to the above configuration, the guide wire is sandwiched between the base film and the adhesive layer, so that the guide wire does not form the outer surface of the inspection seal. Therefore, the guide wire does not easily come off from the inspection seal.

In the inspection seal, the separate film that is detachably laminated on the surface of the base film opposite to the guide surface and the surface of the adhesive layer opposite to the surface in contact with the base film. A protective film laminated so as to be peelable, and a portion of the separate film, the base film, and the laminated body of the adhesive layer excluding the index, all light rays specified in JIS K 7361-1. The transmittance may be 30% or more.

According to the above configuration, the total light transmittance is 30% or more in the portion of the separate film, the base film, and the laminated body of the adhesive layer excluding the guide line. Therefore, when attaching the inspection sticker to the inspection target, it is possible to adjust the position of the inspection sticker with respect to the inspection target while visually checking the position of the guide line with respect to the inspection target simply by peeling off the protective film from the adhesive layer. It is possible.

In the inspection sticker, the index is a coordinate grid including a plurality of grid lines extending along the scanning direction and arranging along the direction intersecting the scanning direction, and in the plurality of grid lines, the first The grid lines of the color of 1 and the grid lines of the second color different from the first color may be arranged alternately.

According to the above configuration, when the inspector scans the probe along the scanning direction, the scanning along the grid line having the first color and the scanning along the grid line having the second color are performed. Can be performed alternately. This prevents the inspector from scanning the same grid line multiple times or leaking a scan of a certain grid line. That is, it is possible to reduce scanning errors by the inspector.

The inspection sticker may further include a sign indicating a predetermined coordinate in the coordinate grid. According to the above configuration, when using the inspection sticker, it is possible to superimpose predetermined coordinates on a specific position of the inspection target.

In the inspection seal, the base film is formed of a polyurethane resin, and the polyurethane resin is at least one selected from the group composed of an ether-based polyurethane resin, an ester-based polyurethane resin, and a carbonate-based polyurethane resin. May include. According to the above configuration, it is possible to obtain a base film having high bonding suitability.

According to the present invention, it can be easily attached to an inspection target.

The cross-sectional view which shows the structure of the 1st example in the inspection seal in 1st Embodiment. The cross-sectional view which shows the structure of the 2nd example in the inspection seal in 1st Embodiment. The plan view which shows the structure of the inspection seal in the plan view which faces the surface of a base film. The cross-sectional view which shows the structure of the laminated body when the inspection seal of 1st example is used. The structure of the laminate when the inspection seal of the second example is used. The schematic diagram for demonstrating the usage of the inspection seal. A table showing measurement results and evaluation results of Examples and Comparative Examples of the first embodiment. The cross-sectional view which shows the structure of the inspection seal in 2nd Embodiment. Sectional drawing which shows the structure of a laminated body when an inspection seal is used. The schematic diagram for demonstrating the usage of the inspection seal. A table showing measurement results and evaluation results of Examples and Comparative Examples of the second embodiment. A table showing measurement results and evaluation results of Examples and Comparative Examples of the second embodiment.

[First Embodiment]
A first embodiment of the inspection seal will be described with reference to FIGS. 1 to 7. In the following, the configuration of the inspection seal, the method of using the inspection seal, and the examples will be described in order.

[Construction of inspection seal]
The configuration of the inspection seal will be described with reference to FIGS. 1 to 3. In the following, the configuration of the inspection seal in the first example will be described with reference to FIG. 1, and the configuration of the inspection seal in the second example will be described with reference to FIG. After that, the configuration common to the first example of the inspection seal and the second example of the inspection seal will be described with reference to FIG.

The inspection sticker 10 shown in FIG. 1 is a sticker used for mammography, which is an example of image diagnosis using microwaves. The inspection sticker 10 is a sticker attached to the breast to be inspected in mammography.

The first example of the inspection seal 10 includes a base film 11. The base film 11 is a film that has a coordinate grid 12 for guiding the position of the scan in the inspection target and is attached to the inspection target. The coordinate grid 12 is an example of a scan index. The base film 11 of the present embodiment satisfies the following two conditions.
(Condition 1-1) The tensile elongation at break is 130% or more.
(Condition 1-2) 100% elongation and tensile strength is 4 N / cm or less.

The inspection seal 10 has a tensile elongation at break suitable for sticking to an inspection target and a 100% tensile tensile strength. Therefore, according to the inspection sticker 10, it is easy to attach the sticker to the inspection target.

The tensile elongation at break can be determined in accordance with JIS K 7161-1: 2014 (ISO 527-1) and JIS K 7127: 1999 (ISO 527-3). When the object to be measured does not have a yield point, the tensile fracture strain is measured, and when the object has a yield point, the nominal strain at the time of tensile fracture is measured, and the tensile elongation at break is obtained using these measured values. it can.

The 100% elongation-tensile strength is the width of the test piece measured when the strain defined in JIS K 7161-1: 2014 (ISO 527-1) reaches the specified value (100%). It is the value divided by. The 100% elongation-tensile strength (T) (N / cm) can be calculated by the following formula.

T = F / W
In the above formula, F is the magnitude of the measured force (N), and W is the width (cm) of the test piece.

It is preferable that the base film 11 further satisfies the following conditions.
(Condition 1-3) It has a transmittance of 70% or more with respect to microwaves having a frequency of 2 GHz.

In mammography using the inspection sticker 10, a probe that oscillates a microwave having a frequency of 2 GHz is used. Since the base film 11 has a transmittance of 70% or more with respect to the microwave of 2 GHz, it is possible to suppress the attenuation of the microwave oscillated from the probe. This improves the accuracy of the image obtained as a result of scanning. As a result, the accuracy of diagnostic imaging is improved.

The polyurethane resin for forming the base film 11 includes at least one selected from the group composed of an ether-based polyurethane resin, an ester-based polyurethane resin, and a carbonate-based polyurethane resin. This makes it possible to obtain a base film 11 having high bonding suitability.

The ether-based polyurethane resin is a polyurethane resin produced by using an ether-based polyol containing an ether bond (-O-). The ester-based polyurethane resin is a polyurethane resin produced by using an ester-based polyol containing an ester bond (-COO-). The carbonate-based polyurethane resin is a polyurethane resin produced by using a polyol containing a carbonate bond (-OC (= O) O-). The thickness of the base film 11 may be, for example, 5 μm or more and 30 μm or less.

The base film 11 has a pair of surfaces facing each other. The pair of surfaces is composed of a front surface 11F and a back surface 11R. In this embodiment, the coordinate grid 12 is located on the back surface 11R. The base film 11 is transparent or translucent. In the portion of the base film 11 excluding the coordinate grid 12, the total light transmittance defined in JIS K 7361-1 is preferably 30% or more, and more preferably 50% or more.

The inspection seal 10 further includes a separate film 13 and a protective film 14. The separate film 13 is detachably laminated on the surface 11F of the base film 11. The protective film 14 is detachably laminated on the back surface 11R of the base film 11. In the portion of the inspection sticker 10 excluding the coordinate grid 12, the total light transmittance defined in JIS K7361-1 is preferably 30% or more, and more preferably 50% or more.

The protective film 14 covers the back surface 11R. As a result, the coordinate grid 12 is sandwiched between the base film 11 and the protective film 14, so that the coordinate grid 12 does not form the outer surface of the inspection seal 10. Therefore, the coordinate grid 12 is hard to peel off from the base film 11. The protective film 14 covers the entire base film 11 when viewed from the direction in which the base film 11 and the protective film 14 overlap. In the protective film 14, the surface in contact with the base film 11 is the front surface 14F, and the surface facing the front surface 14F is the back surface 14R. The protective film 14 covers the entire coordinate grid 12 and has a thickness such that the back surface 14R becomes a substantially flat surface. The protective film 14 is transparent or translucent. The total light transmittance of the protective film 14 is preferably 30% or more, and more preferably 50% or more.

The total light transmittance is 30% or more in the portion of the inspection sticker 10 excluding the coordinate grid 12. Therefore, when the inspection sticker 10 is attached to the breast, it becomes easy to visually confirm the position of the coordinate grid 12 with respect to the breast. Therefore, it is possible to adjust the position of the inspection sticker 10 with respect to the breast while confirming the position of the coordinate grid 12 with respect to the breast. Further, if the total light transmittance of the inspection sticker 10 is 30% or more, after the base film 11 is attached to the breast, the positions of moles and stains located on the breast via the base film 11 can be visually checked or photographed. Easy to identify by. The location of moles and spots on the breast is important in determining the location of lesions on the breast, as the location of moles and stains on the breast does not change.

In the inspection sticker 10, the base film 11 is attached to the subject. In the inspection seal 10, the separate film 13 and the protective film 14 sandwich the base film 11 in the thickness direction of the base film 11. Therefore, the base film 11 is protected from the outside by the separate film 13 and the protective film 14 until just before the base film 11 is attached to the subject. Therefore, the base film 11 is kept clean until it is attached to the subject.

The separate film 13 and the protective film 14 are preferably films made of transparent or translucent synthetic resin. Each of the films 13 and 14 is composed of, for example, a base film and a release layer. The release layer is laminated on the base film. The release layer of the separate film 13 is in contact with the surface 11F of the base film 11. Further, the release layer of the protective film 14 is in contact with the back surface 11R of the base film 11. The base film may be, for example, a polyethylene terephthalate (PET) film or the like. The release layer may be, for example, a layer made of silicone resin. Each of the films 13 and 14 may be composed of only the base film, and the surface of the base film in contact with other layers may be processed to improve the peelability.

A part of the separate film 13 may be half-cut. In other words, the separate film 13 may have a notch extending from the surface to the middle of the separate film 13 in the thickness direction of the separate film 13. In the separate film 13, the surface opposite to the surface in contact with the base film 11 is the surface.

As shown in FIG. 2, the second example of the inspection seal 10 further includes a fluidized bed 15 in addition to the base film 11, the separate film 13, and the protective film 14. The fluidized bed 15 is composed of an aliphatic hydrocarbon that transmits microwaves more than water, and is laminated on the base film 11 with a viscosity that allows the base film 11 to be attached to the breast. That is, the transmittance of microwaves in the fluidized bed 15 is higher than the transmittance of microwaves in water. This makes it easier to attach the base film 11 to the breast because the step of applying the agent for attaching the base film 11 to the breast to the inspection target can be omitted.

In the second example of the inspection seal 10, it is more preferable that the laminate of the base film 11 and the fluidized bed 15 satisfies the above-mentioned conditions 1-3. As a result, when the base film 11 is attached to the inspection target via the fluidized bed 15, it is possible to suppress the attenuation of the microwave oscillated from the probe. Therefore, the accuracy of the image obtained as a result of scanning is improved. As a result, the accuracy of diagnostic imaging is improved.

The fluidized bed 15 is composed of an ointment-like aliphatic hydrocarbon. In the present embodiment, the fluidized bed 15 covers the back surface 11R of the base film 11. As a result, the coordinate grid 12 is sandwiched between the base film 11 and the fluidized bed 15, so that the coordinate grid 12 does not form the outer surface of the inspection seal 10. Therefore, the coordinate grid 12 is hard to peel off from the base film 11.

The fluidized bed 15 is located between the base film 11 and the protective film 14 in the thickness direction of the inspection seal 10. In the fluidized bed 15, the surface in contact with the base film 11 is the front surface 15F, and the surface opposite to the front surface 15F is the back surface 15R. The fluidized bed 15 covers the entire coordinate grid 12 and has a thickness such that the back surface 15R becomes a substantially flat surface. The fluidized bed 15 is transparent or translucent.

In the fluidized bed 15, the shear viscosity at 30 ° C. is preferably 1000 mPa · s or more and 200,000 mPa · s or less. In the fluidized bed 15, the shear viscosity at 30 ° C. is more preferably 5000 mPa · s or more and 50,000 mPa · s or less. The shear viscosity is the shear viscosity specified in JIS Z8803: 2011.

When the shear viscosity is 1000 mPa · s or more, the certainty that the fluidized bed 15 attaches the base film 11 to the breast can be increased. On the other hand, when the shear viscosity is 200,000 mPa · s or less, wrinkles and sagging are suppressed in the base film 11 when the fluidized bed 15 is formed on the base film 11 by coating. In addition, when the shear viscosity is 200,000 mPa · s or less, the stickiness of the fluidized bed 15 is suppressed from causing discomfort to the subject, and the fluidized bed 15 is suppressed from being difficult to wipe off.

The fluidized bed 15 is preferably composed of at least one selected from the group composed of paraffin, squalane, and selecin. According to these materials, the fluidized bed 15 can reliably transmit microwaves and reduce the irritation to the skin of the subject.

As shown in FIG. 3, the coordinate grid 12 includes a plurality of grid lines 12A. Each grid line 12A extends along the scan direction DS, and the plurality of grid lines 12A are arranged along the arrangement direction DA intersecting the scan direction DS. In the present embodiment, the left-right direction of the paper surface is the scanning direction DS. The scan direction DS is a direction in which an inspector such as a doctor or an inspector scans an inspection target using a probe in mammography. Further, in the present embodiment, the arrangement direction DA is the vertical direction of the paper surface. The arrangement direction DA is a direction orthogonal to the scanning direction DS. In the plurality of grid lines 12A, the first grid line 12A1 of the first color and the second grid line 12A2 of the second color different from the first color are alternately arranged.

The first grid line 12A1 may be, for example, red, and the second grid line 12A2 may be, for example, blue. The first color, which is the color of the first grid line 12A1, and the second color, which is the color of the second grid line 12A2, are not limited to red and blue, and can be arbitrarily set as long as they are different colors. It is possible to do.

The coordinate grid 12 further includes a plurality of grid lines 12B extending along the array direction DA and lining up along the scan direction DS. When viewed from the direction facing the plane on which the inspection seal 10 spreads, the plurality of grid lines 12B form a square grid together with the plurality of grid lines 12A described above. In each grid line 12B, the first division 12B1 and the second division 12B2 are alternately arranged. In the arrangement direction DA, the first section 12B1 and the second section 12B2 are separated for each section sandwiched by one first grid line 12A1 and one second grid line 12A2. The first division 12B1 has a first color like the first grid line 12A1. The second division 12B2 has a second color like the second grid line 12A2.

The coordinate grid 12 further includes a position marker 12C. In the present embodiment, the position marker 12C is a number used to specify a position on the coordinate grid 12. The position indicator 12C contains, for example, a plurality of numbers arranged along the scan direction DS. The plurality of numbers are located outside the first grid line 12A1 located at the end in the arrangement direction DA. Each number is located between the two grid lines 12B in the scan direction DS, or is located outside the grid lines 12B located at the ends. The position marker 12C contains, for example, a plurality of numbers arranged along the arrangement direction DA. The plurality of numbers are located outside the grid line 12B located at the end in the scanning direction DS. Each number is located between the two grid lines 12A in the arrangement direction DA. The position sign 12C is not limited to a plurality of numbers, and may include, for example, a plurality of characters.

Since the coordinate grid 12 includes the position indicator 12C, the accuracy of the inspection may be further improved by the inspection performer referring to the position indicator 12C. Further, when a lesion is found in the breast, the position marker 12C can be used to identify the position of the lesion in the breast.

The coordinate grid 12 is printed on the back surface 11R of the base film 11 using ink. As the ink for printing the coordinate grid 12, any ink capable of printing on the base film 11 can be used.

The inspection sticker 10 further includes a sign 16 indicating a predetermined position on the coordinate grid 12. In the present embodiment, the predetermined position is the central portion of the coordinate grid 12. The sign 16 is a circular point located at the center of the coordinate grid 12. The shape of the sign 16 is not limited to a circular shape and can be set arbitrarily. Further, the marker 16 may be composed of a plurality of portions separated from each other. Further, the sign 16 may be arranged at a position deviated from the central portion of the coordinate grid 12 as long as it indicates the central portion of the coordinate grid 12. Like the coordinate grid 12, the marker 16 may be printed on the back surface 11R of the base film 11 using ink.

[How to use the inspection sticker]
A method of using the inspection seal 10 will be described with reference to FIGS. 4 to 6. The usage method of the inspection seal 10 in the first example will be described with reference to FIG. 4, and the usage method of the inspection seal 10 in the second example will be described with reference to FIG.

As shown in FIG. 4, when using the first example of the inspection sticker 10, the user first peels off the separate film 13 and the protective film 14 from the base film 11. When using the first example of the inspection seal 10, the separate film 13 may be peeled off before the protective film 14, or the protective film 14 may be peeled off before the separate film 13.

When the first example of the inspection seal 10 is used, an aliphatic hydrocarbon having an ointment-like shape equivalent to the material constituting the fluidized bed 15 is applied to the breast of the subject. Then, the base film 11 is attached to the breast via an ointment-like aliphatic hydrocarbon. In order to carry out the inspection smoothly, it is preferable to apply an ointment-like aliphatic hydrocarbon to the breast before peeling the separate film 13 and the protective film 14 from the base film 11. When the first example of the inspection seal 10 is used, it is more preferable that the laminate of the aliphatic hydrocarbon applied to the breast and the base film 11 satisfies the above-mentioned conditions 1-3.

Further, as shown in FIG. 5, when using the second example of the inspection seal 10, the user peels the separate film 13 from the base film 11 and the protective film 14 from the fluidized bed 15. As in the case of using the first example of the inspection seal 10, the separate film 13 may be peeled off before the protective film 14, or the protective film 14 may be peeled off before the separate film 13.

As shown in FIG. 6, whether the first example of the inspection seal 10 is used or the second example of the inspection seal 10 is used, the base is via the ointment-like aliphatic hydrocarbon H. The film 11 is attached to the breast B of the subject S. At this time, the inspection sticker 10 is attached to the breast B so that the sign 16 of the inspection sticker 10 overlaps the nipple. In the present embodiment, since the marker 16 is located at the center of the coordinate grid 12, a part of the coordinate grid 12 is positioned in the entire circumferential direction of the papilla by overlapping the marker 16 and the papilla. Can be done. As a result, the guidance of the coordinate grid 12 facilitates scanning of the entire breast B.

When the base film 11 is attached to the breast B, the position of the marker 16 is aligned with the position of the nipple while the four sides constituting the edge of the base film 11 are pulled outward. Next, by gradually attaching the base film 11 to the breast B from the upper end to the lower end of the base film 11, wrinkling of the base film 11 can be suppressed. In the base film 11, the side located above the papilla is the upper end, and the side located below the papilla is the lower end. When the base film 11 is wrinkled, a force is applied to the base film 11 to peel off the wrinkled portion of the base film 11 from the breast B and pull the base film 11 toward the outside of the edge. In this state, the base film 11 is attached to the breast B. As a result, it is possible to remove the wrinkles generated on the base film 11.

When the base film 11 is attached to the breast B, a jig capable of pulling the base film 11 toward the outside of the edge of the base film 11 may be used. Further, as described above, when the separate film 13 is half-cut, the base film 11 may be attached to the breast B by the following procedure. That is, after the protective film 14 is peeled off from the base film 11 or the fluidized bed 15, the laminate of the separate film 13 and the base film 11 is attached to the breast B via the ointment-like aliphatic hydrocarbon H. Then, the separate film 13 is peeled off from the base film 11.

As described above, in the present embodiment, the grid lines 12A extending along the scan direction DS include the first grid lines 12A1 and the second grid lines 12A2 having different colors, and in the arrangement direction DA, The first grid line 12A1 and the second grid line 12A2 are arranged alternately. Therefore, when the inspector scans the probe along the scan direction DS, the scan along the first grid line 12A1 and the scan along the second grid line 12A2 can be alternately performed. As a result, it is possible to prevent the inspector from scanning the same grid line 12A multiple times or leaking a scan of a certain grid line 12A. That is, according to the grid line 12A, it is possible to reduce scanning errors by the inspector.

[Example]
Examples and comparative examples of the inspection seal will be described with reference to FIG. 7.
[Comparative Example 1-1]
A PET film having a thickness of 12 μm (Toray Industries, Inc., Lumirror S10) (Lumilar is a registered trademark) was prepared as a base film of Comparative Example 1-1.

[Comparative Example 1-2]
A PET film having a thickness of 4.5 μm (manufactured by Toray Industries, Inc., Lumirror F48) was prepared as a base film of Comparative Example 1-2.

[Comparative Example 1-3]
As a separate film, a PET film (manufactured by Toray Industries, Inc., Therapy BX-9) having a release layer and a thickness of 75 μm (Therapele is a registered trademark) was prepared. Then, using a separate film as a support, EVA resin (ethylene-vinyl acetate copolymer resin) (Japan Polyethylene Corporation, Novatec LV440) (Novatec is a registered trademark) is extruded and laminated to achieve a thickness of 30 μm. The provided EVA film was formed as a base film. Then, the separate film was peeled off to obtain a base film of Comparative Example 1-3.

[Example 1-1]
A base film of Example 1-1 was obtained by the same method as in Comparative Example 1-3 except that the thickness of the base film was changed to 15 μm in Comparative Example 1-3.

[Example 1-2]
A base film of Example 1-2 was obtained by the same method as in Comparative Example 1-3 except that the thickness of the base film was changed to 5 μm in Comparative Example 1-3.

[Example 1-3]
A PU film having a thickness of 30 μm and formed of an ether-based polyurethane resin (Esmer URS manufactured by Nihon Matai Co., Ltd.) (Esmer is a registered trademark) was prepared as a base film of Example 1-3.

[Example 1-4]
A PU film having a thickness of 15 μm and formed from an ether-based polyurethane resin (Silklon HVL85 manufactured by Okura Industrial Co., Ltd.) (Silklon is a registered trademark) was prepared as the base film of Examples 1-4.

[Example 1-5]
A PU film having a thickness of 5 μm (thin film urethane film manufactured by Nakajima Kogyo Co., Ltd.) was prepared as the base film of Example 1-5.

[Example 1-6]
A water transfer type tattoo sticker (3M Japan Ltd., A-One transfer sticker part number: 52103) was prepared. Then, a PVA layer, which is an image receiving layer having a thickness of 5 μm, was prepared as a base film of Examples 1-6.

[Evaluation method]
[Tensile breaking elongation]
Make each inspection seal into a dumbbell shape (test piece type 5) by a method that complies with JIS K 7127: 1999 "Plastic-Tensile Specific Test Method-Part 3: Film and Sheet Test Conditions". After cutting, the tensile elongation at break was measured for each test piece by a method according to JIS K7161-1: 2014. Specifically, the tensile elongation at break was measured using a universal testing machine (manufactured by Shimadzu Corporation, Autograph AGS-X load cell 1 kN). The test piece was fixed at two points by the fixed grip device of the universal testing machine, and the distance between the tips of the fixed grip device at this time was set to 80 mm. Then, the tensile speed was set to 300 mm / min, the test piece was pulled between the fixed portions of the test piece, and the breaking elongation of the test piece was determined.

[100% elongation and tensile strength]
Make each inspection seal into a dumbbell shape (test piece type 5) by a method that complies with JIS K 7127: 1999 "Plastic-Tensile Specific Test Method-Part 3: Film and Sheet Test Conditions". After cutting, 100% tensile tensile strength was calculated for each test piece by a method conforming to JIS K 7161-1: 2014. Specifically, a universal testing machine (same as above) was used to calculate 100% tensile tensile strength. The test piece was fixed at two points by the fixed grip device of the universal testing machine, and the distance between the tips of the fixed grip device at this time was set to 80 mm. Then, the tensile speed is set to 300 mm / min, the test piece is pulled between the fixed points of the test piece, and the magnitude of the measured force is divided by the width of the test piece to calculate the 100% elongation tensile strength. did.

[Adhesion suitability]
A model for breast cancer palpation training (manufactured by Tanak Co., Ltd.) was used to evaluate the suitability of applying the test sticker. The base film was attached to the breast of the model using an ointment-like aliphatic hydrocarbon formed of paraffin and having a shear viscosity of 10000 mPa · s at 30 ° C., and the following items were evaluated. The viscosity of the aliphatic hydrocarbon was measured by the following method. For the aliphatic hydrocarbon to be measured, use a B-type viscometer (TVB-25L TM rotor 2 manufactured by Toki Sangyo Co., Ltd.) according to the "Viscosity measurement method using a single cylindrical rotational viscometer" in JIS Z 8803: 2011. It was measured while being held at 30 ° C. using (attachment). As the aliphatic hydrocarbon, the aliphatic hydrocarbon after stirring for 1 minute was used.

(Item 1) Wrinkles on the inspection sticker In item 1, whether or not the base film was wrinkled when the base film was attached to the breast was evaluated in the following three stages. Of the following three stages, the base film having an evaluation of "◯" or "Δ" is an inspection sticker having adhesive suitability.

○ No wrinkles △ Fine wrinkles occur, but there is no problem in the inspection × Wrinkles that are large enough to interfere with the inspection occur

[Evaluation results]
The results of each evaluation will be described with reference to FIG. 7.
As shown in FIG. 7, in the case of a base film made of EVA resin, it was confirmed that a base film having bonding suitability can be obtained by reducing the thickness to 15 μm or less. Further, it was confirmed that in the case of a base film made of polyurethane resin, a base film having bonding suitability can be obtained even if the thickness of the base film is 30 μm. However, when the thickness of the base film is 30 μm, the base film is wrinkled to the extent that it does not interfere with the inspection. Therefore, the thickness of the base film made of polyurethane resin is preferably 30 μm or less. Further, it was confirmed that wrinkles did not occur even when the base film made of PVA resin was used.

On the other hand, it was found that the base film made of PET resin had low bonding suitability. It can be said that these results were obtained because the tensile strength of the PET resin base film was low and the base film did not stretch when the base film was attached to the inspection target.

As described above, according to the base film having a tensile elongation at break of 130% or more and a 100% elongation / tensile strength of 4 N / cm or less, it is possible to improve the bonding suitability.
As described above, according to the first embodiment of the inspection seal, the effects listed below can be obtained.

(1-1) The inspection seal 10 has a tensile elongation at break suitable for attachment to the breast B and a 100% tensile tensile strength. Therefore, according to the inspection sticker 10, it is easy to attach the sticker to the breast B.

(1-2) Since the base film 11 is formed of at least one of an ether-based polyurethane resin, an ester-based polyurethane resin, and a carbonate-based polyurethane resin, it is possible to obtain a base film 11 having high bonding suitability. is there.

(1-3) When the inspection seal 10 includes the fluidized bed 15, the step of applying the agent for attaching the base film 11 to the breast B to the breast B can be omitted, and the step of applying the base film 11 to the breast B can be omitted. It is easier to paste.

(1-4) When the shear viscosity of the fluidized bed 15 is 1000 mPa · s or more, the certainty that the fluidized bed 15 attaches the base film 11 to the breast B can be increased.

(1-5) When the shear viscosity of the fluidized bed 15 is 200,000 mPa · s or less, wrinkles and sagging are suppressed in the base film 11 when the fluidized bed 15 is formed on the base film 11 by coating. ..

(1-6) By forming the fluidized bed 15 from at least one of paraffin, squalane, and selecin, the fluidized bed 15 reliably transmits microwaves and reduces irritation to the skin of the subject. can do.

[Example of modification of the first embodiment]
The above-described first embodiment can be modified and implemented as follows.
[Coordinate grid]
The coordinate grid 12 does not have to have the grid line 12B. As long as the coordinate grid 12 has at least grid lines 12A, it is possible to suppress scanning errors by the inspector. That is, the base film 11 is not limited to the coordinate grid 12, and may have a scan index having another shape such as a shape extending along one direction. The scanning index may be, for example, a probe that guides the position to be scanned or guides the scanning direction.

The coordinate grid 12 does not have to have the position marker 12C. As long as the coordinate grid 12 has at least grid lines 12A, it is possible to suppress scanning errors by the inspector.

-All grid lines 12A may have the same color. Even in this case, the grid line 12A can guide the direction of scanning by the probe.

The coordinate grid 12 may have a shape other than the square grid in a plan view facing the surface 11F of the base film 11. For example, the coordinate grid 12 may be composed of a plurality of concentric circles having different diameters from each other. That is, the coordinate grid 12 may be a grid corresponding to polar coordinates. In short, the coordinate grid 12 may have a shape capable of guiding the direction and position of scanning the probe while being attached to the breast B.

The coordinate grid 12 does not have to be formed by printing. For example, the coordinate grid 12 may be formed by recesses and protrusions of the base film 11.

[Sign]
-Sign 16 may be omitted. Even in this case, if the examination sticker 10 has the coordinate grid 12, the entire position of the coordinate grid 12 with respect to the breast B can be adjusted so that the entire nipple in the circumferential direction is scanned. It is possible to attach the base film 11 to the breast B.

The sign 16 does not have to be formed by printing. For example, the label 16 may be formed by the concave or convex portions of the base film 11.

[Base film]
-If the base film 11 included in the inspection seal 10 satisfies the above-mentioned conditions 1-1 and 1-2, the synthetic resin for forming the base film 11 may be a resin other than the polyurethane resin. .. For example, as is clear from the base film of the test example, the synthetic resin for forming the base film 11 may be an EVA resin, a PVA resin, or the like.

[Fluidized bed]
-The material for forming the fluidized bed 15 is an ointment other than paraffin, squalane, and ceresin, provided that microwaves are more transparent than water and the base film 11 can be attached to the breast B. It may be an aliphatic hydrocarbon having.

-The viscosity of the fluidized bed 15 may be lower than 1000 mPa · s or higher than 200,000 mPa · s as long as the base film 11 can be attached to the breast B by the fluidized bed 15.

[Separate film]
-The separate film 13 may be omitted. Even in this case, if the inspection seal 10 includes the base film 11 that satisfies the above-mentioned conditions 1-1 and 1-2, the effect according to the above-mentioned (1-1) can be obtained. ..

[Protective film]
-The protective film 14 may be omitted. Even in this case, if the inspection seal 10 includes the base film 11 that satisfies the above-mentioned conditions 1-1 and 1-2, the effect according to the above-mentioned (1-1) can be obtained. ..

[Inspection sticker]
-The inspection sticker 10 may have a total light transmittance of 30% or more at least in a portion of the base film 11 other than the coordinate grid 12. In this case, the coordinate grid 12 of the base film 11 can be visually recognized by peeling the separate film 13 from the front surface 11F of the base film 11 and peeling the protective film 14 from the back surface 11R.

In the inspection sticker 10, the total light transmittance may be 30% or more in the portion other than the coordinate grid 12 in the laminated body of the separate film 13 and the base film 11. As a result, when the inspection sticker 10 is attached to the inspection target, the coordinate grid 12 of the base film 11 can be visually recognized regardless of whether the separate film 13 is peeled off from the base film 11 or not. It is possible.

[Inspection target]
-The inspection target is not limited to the breast, but may be other parts of the human body. That is, the inspection sticker 10 may be used not only for mammography but also for other diagnostic imaging.

[Second Embodiment]
A second embodiment of the inspection seal will be described with reference to FIGS. 8 to 12. In the second embodiment, the same reference numerals as those used in the first embodiment are attached to the configurations common to those in the first embodiment. In the following, the configuration of the inspection seal, the method of using the inspection seal, and the examples will be described in order.

[Construction of inspection seal]
The configuration of the inspection seal will be described with reference to FIG.
The inspection sticker 10 is a sticker used for mammography, which is an example of image diagnosis using microwaves, like the inspection sticker 10 of the first embodiment. The inspection sticker 10 is a sticker attached to the breast to be inspected in mammography.

As shown in FIG. 8, the inspection seal 10 includes a base film 11 and an adhesive layer 17. The base film 11 has a coordinate grid 12 for guiding the position of the scan in the inspection target. The coordinate grid 12 is an example of a scan index. The base film 11 is made of polyurethane resin. The adhesive layer 17 is formed of a urethane-based adhesive. The adhesive layer 17 is laminated on the base film 11. The thickness of the adhesive layer 17 is 5 μm or more and 25 μm or less.

In the inspection seal 10 of the present embodiment, the following three conditions are satisfied in the laminated body of the base film 11 and the adhesive layer 17.

(Condition 2-1) The tensile elongation at break specified in JIS K 7127 is 130% or more.
(Condition 2-2) 100% elongation tensile stress is 10 MPa or less.
(Condition 2-3) The moisture permeation specified in JIS Z 0208 is 750 g / m ² · day or more under the conditions of 40 ° C. and 90% relative humidity.

The inspection seal 10 has a tensile elongation at break suitable for sticking to an inspection target and a 100% elongation tensile stress. Therefore, according to the inspection sticker 10, it is easy to attach the sticker to the inspection target and peel it off from the inspection target. Further, when the moisture permeability of the inspection sticker 10 satisfies the above range, sweating in the inspection target can be suppressed when the inspection sticker 10 is attached to the inspection target.

In the inspection seal 10, it is preferable that the following conditions are further satisfied in the laminated body of the base film 11 and the adhesive layer 17.
(Condition 2-4) It has a transmittance of 70% or more with respect to microwaves having a frequency of 2 GHz.

In mammography using the inspection sticker 10, a probe that oscillates a microwave having a frequency of 2 GHz is used. Since the base film 11 has a transmittance of 70% or more with respect to the microwave of 2 GHz, it is possible to suppress the attenuation of the microwave oscillated from the probe. This improves the accuracy of the image obtained as a result of scanning. As a result, the accuracy of diagnostic imaging is improved.

The polyurethane resin for forming the base film 11 includes any one selected from the group composed of an ether-based polyurethane resin, an ester-based polyurethane resin, and a carbonate-based polyurethane resin. As a result, it is possible to obtain a base film 11 having high bonding suitability and high moisture permeability.

When the base film 11 is formed of an ether-based polyurethane resin, the thickness of the base film 11 is preferably 30 μm or less. The thickness of the base film 11 may be, for example, 5 μm or more and 30 μm or less. When the base film 11 is formed of an ester-based polyurethane resin, the thickness of the base film 11 may be, for example, 5 μm or more and 15 μm or less. When the base film 11 is formed of a carbonate-based polyurethane resin, the thickness of the base film may be, for example, 5 μm or more and 15 μm or less.

The base film 11 has a pair of surfaces facing each other. The pair of surfaces is composed of a front surface 11F and a back surface 11R. One of the pair of surfaces is a guide surface on which the coordinate grid 12 is printed. In this embodiment, the coordinate grid 12 is located on the back surface 11R. That is, the back surface 11R is an example of the guide surface. The base film 11 is transparent or translucent. In the base film 11, the total light transmittance defined in JIS K 7361-1 is preferably 30% or more, and more preferably 50% or more.

The adhesive layer 17 covers the back surface 11R. As a result, the coordinate grid 12 is sandwiched between the base film 11 and the adhesive layer 17, so that the coordinate grid 12 does not form the outer surface of the inspection seal 10. Therefore, the coordinate grid 12 is hard to peel off from the inspection sticker 10. When viewed from the direction in which the base film 11 and the adhesive layer 17 overlap, the adhesive layer 17 covers the entire base film 11. In the adhesive layer 17, the surface in contact with the base film 11 is the front surface 17F, and the surface facing the front surface 17F is the back surface 17R. The adhesive layer 17 has a thickness that covers the entire coordinate grid 12 and makes the back surface 17R a substantially flat surface. The adhesive layer 17 is transparent or translucent. The total light transmittance of the adhesive layer 17 is preferably 30% or more, and more preferably 50% or more.

The inspection seal 10 further includes a separate film 13 and a protective film 14. The separate film 13 is detachably laminated on the surface 11F of the base film 11. The protective film 14 is detachably laminated on the back surface 17R of the adhesive layer 17. In the portion of the inspection sticker 10 excluding the coordinate grid 12, the total light transmittance defined in JIS K 7361-1 is preferably 30% or more, and more preferably 50% or more.

In the inspection sticker 10, a laminate of the base film 11 and the adhesive layer 17 is attached to the subject. In the inspection seal 10, the separate film 13 and the protective film 14 sandwich the laminate of the base film 11 and the adhesive layer 17 in the thickness direction of the base film 11. Therefore, the laminate of the base film 11 and the adhesive layer 17 is protected from the outside by the separate film 13 and the protective film 14 until just before they are attached to the subject. Therefore, the base film 11 and the adhesive layer 17 are kept clean until they are attached to the subject.

[How to use the inspection sticker]
A method of using the inspection seal 10 will be described with reference to FIGS. 9 and 10.
As shown in FIG. 9, when using the inspection sticker 10, the user first peels off the separate film 13 from the base film 11 and peels off the protective film 14 from the adhesive layer 17. When the inspection sticker 10 is used, the separate film 13 may be peeled off before the protective film 14, or the protective film 14 may be peeled off before the separate film 13.

As shown in FIG. 10, the adhesive layer 17 is attached to the breast B of the subject S. At this time, the inspection sticker 10 is attached to the breast B so that the sign 16 of the inspection sticker 10 overlaps the nipple. In the present embodiment, since the marker 16 is located at the center of the coordinate grid 12, a part of the coordinate grid 12 is positioned in the entire circumferential direction of the papilla by overlapping the marker 16 and the papilla. Can be done. As a result, the guidance of the coordinate grid 12 facilitates scanning of the entire breast B.

When the laminate of the base film 11 and the adhesive layer 17 is attached to the breast B, the position of the marker 16 is set to the position of the papilla while the four sides forming the edges of the laminate are pulled outward. match. Next, by gradually attaching the laminate to the breast B from the upper end to the lower end of the laminate, wrinkling of the laminate is suppressed. In the laminated body, the side located above the papilla is the upper end, and the side located below the papilla is the lower end. When wrinkles are formed on the laminate, the wrinkled portion of the laminate is peeled off from the breast B, and a force for pulling the laminate toward the outside of the edge is applied to the laminate. The laminate is attached to breast B. Thereby, it is possible to remove the wrinkles generated in the laminated body.

When the laminated body is attached to the breast B, a jig capable of pulling the laminated body toward the outside of the edge of the laminated body may be used. Further, as described above, when the separate film 13 is half-cut, the protective film 14 is peeled off from the adhesive layer 17, and then the separate film 13, the base film 11, and the adhesive layer 17 are formed. The separate film 13 may be peeled off from the base film 11 after the laminate to be formed is attached to the breast B.

[Example]
Examples and comparative examples of the inspection seal will be described with reference to FIGS. 11 and 12.
[Comparative Example 2-1]
A PET film having a thickness of 12 μm (Toray Industries, Inc., Lumirror S10) (Lumilar is a registered trademark) was prepared as a base film. In addition, a protective film having a thickness of 38 μm and composed of a PET film and a release layer (Toray Film Processing Co., Ltd., Therapy WZ) (Therapele is a registered trademark) was prepared. An acrylic pressure-sensitive adhesive (HiPAS10 manufactured by Cosmedy Pharmaceutical Co., Ltd.) (HiPAS is a registered trademark) was applied to the protective film by gravure coating, and the acrylic pressure-sensitive adhesive was dried. As a result, an adhesive layer having a thickness of 20 μm was obtained. Next, a laminate was obtained by laminating the base film and the adhesive layer. By aging the laminate in an environment of 40 ° C., an inspection seal of Comparative Example 2-1 was obtained.

[Comparative Example 2-2]
In Comparative Example 2-1 by the same method as in Comparative Example 2-1 except that the base film was changed to a PET film having a thickness of 4.5 μm (manufactured by Toray Industries, Inc., Lumirror F48), Comparative Example 2 An inspection seal of -2 was obtained.

[Comparative Example 2-3]
As a separate film, a PET film (manufactured by Toray Industries, Inc., Therapy BX-9) having a release layer and a thickness of 75 μm was prepared. Then, using a separate film as a support, EVA resin (Japan Polyethylene Corporation, Novatec LV440) (Novatec is a registered trademark) is extruded and laminated to form an EVA film having a thickness of 30 μm as a base film. did. Other than that, the inspection seal of Comparative Example 2-3 was obtained by the same method as in Comparative Example 2-1. When the adhesive layer coated on the protective film and the base film were attached, a laminate of the separate film and the base film was attached to the adhesive layer. Then, after aging the laminate composed of the separate film, the base film, the adhesive layer, and the protective film, the separate film was peeled off and used as an inspection seal of Comparative Example 2-3.

[Comparative Example 2-4]
An inspection seal of Comparative Example 2-4 was obtained by the same method as in Comparative Example 2-3 except that the thickness of the base film was changed to 15 μm in Comparative Example 2-3.

[Example 2-1]
An inspection seal of Example 2-1 was obtained by the same method as in Comparative Example 2-3 except that the thickness of the base film was changed to 5 μm in Comparative Example 2-3.

[Example 2-2]
In Example 2-1 according to the same method as in Example 2-1 except that the adhesive layer was formed by using a urethane-based adhesive (manufactured by Toyochem Co., Ltd., SP-205). An inspection seal was obtained. When forming the adhesive layer, the adhesive layer is formed by adding 1% of a curing agent (manufactured by Toyochem Co., Ltd., T-501B) to the urethane adhesive and then stirring the urethane adhesive. A coating solution for forming the above was obtained.

[Example 2-3]
In Comparative Example 2-1 the same method as in Comparative Example 2-1 except that the base film was changed to a PU film having a thickness of 30 μm (Nihon Matai Co., Ltd., Esmer URS) (Esmer is a registered trademark). Obtained an inspection seal of Example 2-3.

[Example 2-4]
An inspection seal of Example 2-4 was obtained by the same method as in Example 2-3 except that the thickness of the adhesive layer was changed to 10 μm in Example 2-3.

[Example 2-5]
An inspection seal of Example 2-5 was obtained by the same method as in Example 2-3 except that the thickness of the adhesive layer was changed to 5 μm in Example 2-3.

[Example 2-6]
An inspection seal of Example 2-6 was obtained by the same method as in Example 2-3 except that the thickness of the adhesive layer was changed to 30 μm in Example 2-3.

[Example 2-7]
A PU film (Esmer URS, manufactured by Nihon Matai Co., Ltd.) having a thickness of 30 μm and formed of an ether-based polyurethane resin was prepared as a base film. In addition, a protective film (Cerapeel WZ, manufactured by Toray Film Processing Co., Ltd.) having a thickness of 30 μm and composed of a PET film and a release layer was prepared. A 1% curing agent (manufactured by Toyochem Co., Ltd., T-501B) was added to a urethane adhesive (manufactured by Toyochem Co., Ltd., SP-205), and these were stirred to prepare a coating liquid. Next, the coating liquid was applied to the protective film by gravure coating, and the urethane adhesive was dried. As a result, an adhesive layer having a thickness of 20 μm was obtained. Then, a laminate was obtained by laminating the base film and the adhesive layer. The laminate was aged in an environment of 40 ° C. to obtain an inspection seal of Example 2-7.

[Example 2-8]
An inspection seal of Example 2-8 was obtained by the same method as in Example 2-7 except that the thickness of the adhesive layer was changed to 10 μm in Example 2-7.

[Example 2-9]
An inspection seal of Example 2-9 was obtained by the same method as in Example 2-7 except that the thickness of the adhesive layer was changed to 5 μm in Example 2-7.

[Example 2-10]
An inspection seal of Example 2-10 was obtained by the same method as in Example 2-7 except that the thickness of the adhesive layer was changed to 30 μm in Example 2-7.

[Example 2-11]
In Comparative Example 2-1 except that the base film was changed to a PU film (manufactured by Okura Industrial Co., Ltd., Silklon HVL85) (Silklon is a registered trademark) having a thickness of 15 μm and formed from an ether-based polyurethane resin. Obtained an inspection seal of Example 2-11 by the same method as in Comparative Example 2-1.

[Example 2-12]
In Example 2-7, except that the base film was changed to a PU film (manufactured by Okura Industrial Co., Ltd., Silklon HVL85) having a thickness of 15 μm and formed of an ether-based polyurethane resin. An inspection seal of Example 2-12 was obtained by the same method as in 7.

[Example 2-13]
In Comparative Example 2-1 by the same method as in Comparative Example 2-1 except that the base film was changed to a PU film having a thickness of 5 μm (thin film urethane film manufactured by Nakajima Kogyo Co., Ltd.). A 2-13 inspection seal was obtained.

[Example 2-14]
An inspection seal of Example 2-14 was obtained by the same method as in Example 2-13 except that the thickness of the adhesive layer was changed to 10 μm in Example 2-13.

[Example 2-15]
An inspection seal of Example 2-15 was obtained by the same method as in Example 2-13 except that the thickness of the adhesive layer was changed to 5 μm in Example 2-13.

[Example 2-16]
An inspection seal of Example 2-16 was obtained by the same method as in Example 2-13 except that the thickness of the adhesive layer was changed to 30 μm in Example 2-13.

[Example 2-17]
In Example 2-7, the same method as in Example 2-7 was used except that the base film was changed to a PU film having a thickness of 5 μm (thin film urethane film manufactured by Nakajima Kogyo Co., Ltd.). An inspection seal of 2-17 was obtained.

[Example 2-18]
An inspection seal of Example 2-18 was obtained by the same method as in Example 2-17 except that the thickness of the adhesive layer was changed to 10 μm in Example 2-17.

[Example 2-19]
An inspection seal of Example 2-19 was obtained by the same method as in Example 2-17 except that the thickness of the adhesive layer was changed to 5 μm in Example 2-17.

[Example 2-20]
An inspection seal of Example 2-20 was obtained by the same method as in Example 2-17 except that the thickness of the adhesive layer was changed to 30 μm in Example 2-17.

[Example 2-21]
A water transfer type tattoo sticker (3M Japan Ltd., A-One transfer sticker part number: 52103) was prepared. Then, instead of the base film, the enclosed adhesive layer was attached to the PVA layer which is the image receiving layer to obtain an inspection sticker of Example 2-21. Since the PVA layer is applied to the release paper, the PVA layer was attached to the adhesive layer, and then the release paper was moistened with a tissue moistened with water to transfer the PVA layer to the adhesive layer. As a result, the PVA layer was peeled off from the paper pattern. Then, the laminated body containing the PVA layer and the adhesive layer is left to stand in an environment of 40 ° C. for 2 hours to sufficiently dry the surface of the PVA layer, and then the inspection seal of Example 2-21 is evaluated. It was. Further, when the inspection sticker of Example 2-21 is attached, the laminate of the release paper and the PVA layer is attached to the adhesive layer laminated on the separate film, and then the separate film of the adhesive layer is peeled off. It was. Then, the adhesive layer was attached to the object, and then the release paper was moistened to peel the release paper from the PVA layer. In this state, the sticking suitability of the inspection seal of Example 2-21 was evaluated.

[Example 2-22]
As a separate film, a PET film (manufactured by Toray Industries, Inc., Therapy BX-9) having a release layer and a thickness of 75 μm was prepared. Then, an aqueous polyurethane containing an ester-based polyol (Takelac WS-5984, manufactured by Mitsui Chemicals, Inc.) (Takelac is a registered trademark) was applied and then dried. Then, the dried layer was aged at room temperature for 2 days to obtain a base film having a thickness of 15 μm. An inspection seal of Example 2-22 was obtained by forming an adhesive layer on the base film in the same manner as in Example 2-2.

[Example 2-23]
An inspection seal of Example 2-23 was obtained by the same method as in Example 2-22, except that the thickness of the adhesive layer was changed to 10 μm in Example 2-22.

[Example 2-24]
An inspection seal of Example 2-24 was obtained in the same manner as in Example 2-22, except that the thickness of the base film was changed to 5 μm in Example 2-22.

[Example 2-25]
An inspection seal of Example 2-25 was obtained by the same method as in Example 2-24 except that the thickness of the adhesive layer was changed to 10 μm in Example 2-24.

[Example 2-26]
In Example 2-22, the same as in Example 2-22, except that the aqueous polyurethane containing an ester-based polyol was changed to an aqueous polyurethane containing an ether-based polyol (Takelac WS-6021, manufactured by Mitsui Chemicals, Inc.). By the method, an inspection seal of Example 2-26 was obtained.

[Example 2-27]
An inspection seal of Example 2-27 was obtained by the same method as in Example 2-26 except that the thickness of the adhesive layer was changed to 10 μm in Example 2-26.

[Example 2-28]
An inspection seal of Example 2-28 was obtained by the same method as in Example 2-26 except that the thickness of the base film was changed to 5 μm in Example 2-26.

[Example 2-29]
An inspection seal of Example 2-29 was obtained by the same method as in Example 2-28 except that the thickness of the adhesive layer was changed to 10 μm in Example 2-28.

[Example 2-30]
In Example 2-22, the same as in Example 2-22, except that the aqueous polyurethane containing an ester-based polyol was changed to an aqueous polyurethane containing a carbonate-based polyol (Takelac W-6110, manufactured by Mitsui Chemicals, Inc.). By the method, an inspection seal of Example 2-30 was obtained.

[Example 2-31]
An inspection seal of Example 2-31 was obtained by the same method as in Example 2-30 except that the thickness of the adhesive layer was changed to 10 μm in Example 2-30.

[Example 2-32]
An inspection seal of Example 2-32 was obtained by the same method as in Example 2-30 except that the thickness of the base film was changed to 5 μm in Example 2-30.

[Example 2-33]
An inspection seal of Example 2-33 was obtained by the same method as in Example 2-32 except that the thickness of the adhesive layer was changed to 10 μm in Example 2-32.

[Evaluation method]
[Tensile breaking elongation]
The tensile elongation at break was measured by a method according to JIS K 7127 "Plastic-Tensile Specific Test Method-Part 3: Film and Sheet Test Conditions". When measuring the tensile elongation at break, the inspection seal was die-cut into a dumbbell shape (test piece type 5), and the tensile fracture measurement was carried out using a tensile tester. The test speed was set to 300 mm / min, and the distance between marked lines L ₀ was set to 25 mm. The amount of elongation at break was measured, and the elongation at break was calculated. In the tensile fracture measurement, the tensile fracture measurement was performed on the laminate composed of only the base film and the adhesive layer.

[100% elongation tensile stress]
In tensile fracture measurement, the stress when the distance between marked lines L ₀ reaches 100% elongation is divided by the initial value in the cross-sectional area of the inspection seal the tensile force when the elongation of the inspection seal is 100%. It was calculated by doing.

[Adhesion suitability]
A model for breast cancer palpation training (manufactured by Tanak Co., Ltd.) was used to evaluate the suitability of applying the test sticker. An examination sticker was attached to the breast of the model, and the following three items were evaluated.
(Item 1) Wrinkles on the inspection sticker (Item 2) Floating of the inspection sticker (Item 3) Repeated application and peeling of the inspection sticker (reworkability)

In item 1, whether or not the inspection sticker was wrinkled when the inspection sticker was attached to the breast was evaluated in the following three stages. Of the following three stages, the inspection sticker having an evaluation of "○" or "Δ" is an inspection sticker having a sticking suitability.
○ No wrinkles △ Fine wrinkles occur, but there is no problem in the inspection × Wrinkles that are large enough to interfere with the inspection occur

In item 2, when the inspection sticker was attached to the breast, whether or not a part of the inspection sticker was lifted from the breast was evaluated in the following three stages. Of the following three stages, the inspection sticker having an evaluation of "○" or "Δ" is an inspection sticker having a sticking suitability.
○ No floating △ Floating due to unevenness of the nipple occurs, but it does not hinder the inspection × The inspection seal is greatly lifted from the breast, which hinders the inspection

In item 3, the following three stages were evaluated in the operation of attaching the inspection sticker to the breast, then peeling the inspection sticker from the breast once, and then attaching the inspection sticker to the breast again.
○ It is possible to peel off and re-paste the inspection sticker after pasting it △ The inspection sticker is deformed when the inspection sticker is peeled off, but it can be pasted and used again × Peel off the inspection sticker The inspection sticker is torn or the inspection sticker cannot be reattached.

[Humidity permeability]
The moisture permeability of the inspection seal was measured by a method conforming to JIS Z 0208 "Moisture Permeability Test Method for Moisture-Proof Packaging Material (Cup Method)". At the time of measuring the moisture permeability, calcium chloride (anhydrous) was measured as a hygroscopic agent. The initial weight of the moisture permeable cup containing the hygroscopic agent was then measured by an electronic balance. Then, after leaving the inspection seal in an environment of 40 ° C. and 90% relative humidity for 2 hours, the weight of the moisture permeable cup was measured. Then, the increase in the weight of the moisture permeable cup was calculated as the amount of water vapor permeated.

[Sweating survey]
A 5 cm square test piece was cut out from the inspection sticker. Then, the test pieces were attached to the arms of three healthy subjects, and each subject was allowed to stay in a resting state for 5 minutes in a test room at 40 ° C. and a relative humidity of 20%. Then, the test piece was peeled off from each subject, and it was confirmed whether or not sweating occurred in the part of the subject's arm from which the test piece was peeled off.

○ No sweating was observed in all subjects × Sweating was observed in one or more subjects

[Evaluation results]
The results of each evaluation will be described with reference to FIGS. 11 and 12.
As shown in FIG. 11, it was confirmed that by using the base film made of polyurethane resin, wrinkles were suppressed in the inspection seal and the reworkability of the inspection seal was enhanced. When the thickness of the base film is 30 μm, the inspection seal is wrinkled to the extent that it does not interfere with the inspection. Therefore, the thickness of the base film made of polyurethane resin is preferably 30 μm or less. .. Further, when the thickness of the base film is 5 μm, the thickness of the base film is 5 μm or more because the inspection seal is deformed in the reworkability test, although the inspection is not hindered. Is preferable.

Further, by using a base film having high bonding suitability, it is possible to satisfy that the tensile elongation at break of the inspection seal is 420% or more and the 100% elongation tensile stress is 10 MPa or less. Was recognized. It was recognized that this makes it possible to improve the sticking suitability of the inspection sticker. Then, it was confirmed that by using a base film having a high moisture permeability, the moisture permeability of the inspection seal can be set to 783 g / m ² · day or more, and sweating can be suppressed.

On the other hand, it was found that the base film made of PET resin had low bonding suitability. It can be said that these results were obtained because the tensile elongation of the PET resin base film was low and the base film did not stretch when the inspection seal was attached to the inspection target. Further, it is possible to improve the bonding suitability of the EVA resin base film by reducing the thickness to 5 μm. However, the moisture permeability is low, which may cause sweating in the portion to which the inspection sticker is attached to the extent that the inspection is hindered. Further, according to the base film made of PVA resin, it was confirmed that the reworkability of the inspection seal was low because the base film was torn. On the other hand, even when a base film made of PVA resin is used, wrinkles and floating do not occur. Therefore, in order to improve the bonding suitability, the tensile elongation at break may be 130% or more.

As a pressure-sensitive adhesive for forming the pressure-sensitive adhesive layer, it was found that the urethane-based pressure-sensitive adhesive has a higher moisture permeability than the acrylic-based pressure-sensitive adhesive. Further, it was confirmed that by forming the adhesive layer using a urethane-based adhesive, the moisture permeability of the inspection seal can be set to 750 g / m ² · day or more, and thus sweating can be suppressed. .. By reducing the thickness of the adhesive layer, the moisture permeability of the inspection seal can be increased and sweating can be suppressed, but the inspection seal floats due to the unevenness of the nipple. Further, even when the pressure-sensitive adhesive layer is formed by the urethane-based pressure-sensitive adhesive, when the thickness of the pressure-sensitive adhesive layer is 30 μm, sweating by the subject is difficult to be suppressed because the moisture permeability is low. Further, if the thickness of the adhesive layer is too thick, the adhesive strength of the adhesive layer is too strong, which causes a burden on the subject when peeling off the inspection sticker, or inspection depending on the combination with the base film. The seal for use may be torn. In this respect, the thickness of the adhesive layer is preferably 5 μm or more and 25 μm or less.

As shown in FIG. 12, it was confirmed that the tensile elongation at break differs depending on the polyol constituting the polyurethane resin, and thus the test result of the bonding suitability differs. It was found that the base film made of ester-based polyurethane resin or ether-based polyurethane resin is less likely to cause wrinkles because it has a higher tensile elongation at break than the base film made of carbonate-based polyurethane resin. Further, the base film made of carbonate-based polyurethane resin is less likely to be deformed in the reworkability test than the base film made of ester-based polyurethane resin or ether-based polyurethane resin even if the thickness of the base film is thin. Admitted. Further, the base film made of ether-based polyurethane resin has a higher moisture permeability than the base film made of ester-based polyurethane resin or carbonate-based polyurethane resin, so that even if the thickness of the base film is thick, it is inspected. It was found that sweating in the person was suppressed.

As described above, by using the base film made of polyurethane resin having high bonding suitability, it is satisfied that the tensile elongation at break of the inspection seal is 310% or more and the 100% elongation tensile stress is 10 MPa or less. It was recognized that it was possible. It was recognized that this makes it possible to improve the sticking suitability of the inspection sticker. Then, it was confirmed that by using a base film made of polyurethane resin having high moisture permeability, the moisture permeability of the inspection seal can be set to 752 g / m ² · day or more, and sweating can be suppressed.

As described above, according to the second embodiment of the inspection seal, the effects listed below can be obtained.
(2-1) The inspection seal 10 has a tensile elongation at break suitable for attachment to the breast B and a 100% elongation tensile stress. Therefore, according to the inspection sticker 10, it is easy to attach the sticker to the breast B.

(2-2) Further, when the moisture permeability of the inspection sticker 10 satisfies the above range, sweating in the breast B can be suppressed when the inspection sticker 10 is attached to the breast B.

(2-3) Since the coordinate grid 12 is sandwiched between the base film 11 and the adhesive layer 17, the coordinate grid 12 does not form the outer surface of the inspection seal 10. Therefore, the coordinate grid 12 is hard to peel off from the inspection sticker 10.

(2-4) The total light transmittance is 30% or more in the portion of the inspection sticker 10 excluding the coordinate grid 12. Therefore, when the inspection sticker 10 is attached to the breast B, the position of the inspection sticker 10 with respect to the breast B can be adjusted while visually confirming the position of the coordinate grid 12 with respect to the breast B.

(2-5) When the inspector scans the probe along the scan direction DS, the scan along the first grid line 12A1 and the scan along the second grid line 12A2 may be alternately performed. it can. As a result, it is possible to prevent the inspector from scanning the same grid line 12A multiple times or leaking a scan of a certain grid line 12A. That is, according to the grid line 12A, it is possible to reduce scanning errors by the inspector.

(2-6) When the inspection sticker 10 is used, the central portion of the coordinate grid 12 can be overlapped with the papilla of the subject S. Therefore, a part of the coordinate grid 12 can be positioned on the entire circumferential direction of the papilla. As a result, the entire breast B can be easily scanned by the guidance of the coordinate grid 12.

[Example of modification of the second embodiment]
The above-mentioned second embodiment can be modified and implemented as follows.
[Base film]
If the laminate of the base film 11 and the adhesive layer 17 included in the inspection seal 10 satisfies the above-mentioned conditions 2-1 and 2-2, the synthetic resin for forming the base film 11 is a polyurethane resin. It may be a resin other than.

[Adhesive layer]
-If the laminate of the base film 11 and the adhesive layer 17 included in the inspection seal 10 satisfies the above-mentioned conditions 2-1 and 2-2, the adhesive for forming the adhesive layer 17 is urethane-based. An adhesive other than the adhesive may be used.

[Separate film]
-The separate film 13 may be omitted. Even in this case, if the inspection seal 10 includes the base film 11 and the adhesive layer 17, the effect according to (2-1) described above can be obtained.

[Protective film]
-The protective film 14 may be omitted. Even in this case, if the inspection seal 10 includes the base film 11 and the adhesive layer 17, the effect according to (2-1) described above can be obtained.

[Inspection sticker]
-In the inspection sticker 10, the total light transmittance may be 30% or more at least in the portion other than the coordinate grid 12 in the laminated body of the base film 11 and the adhesive layer 17. In this case, the coordinate grid 12 of the base film 11 can be visually recognized by peeling the separate film 13 from the base film 11 and peeling the protective film 14 from the adhesive layer 17.

In the inspection sticker 10, the total light transmittance may be 30% or more in the portion other than the coordinate grid 12 in the laminated body of the separate film 13, the base film 11, and the adhesive layer 17. As a result, when the inspection sticker 10 is attached to the inspection target, the coordinate grid 12 which the base film 11 has is visually recognized regardless of whether the separate film 13 is peeled off from the base film 11 or not. Is possible.

-In the laminated body of the base film 11 and the adhesive layer 17, the moisture permeability may be less than 750 g / m ² · day. Even in this case, as long as the laminate of the base film 11 and the adhesive layer 17 satisfies the above-mentioned conditions 2-1 and 2-2, the effect according to the above-mentioned (2-1) can be obtained. Can be done.

[Other changes]
The inspection seal 10 of the second embodiment and the modification of the inspection seal 10 are within a range consistent with the configuration of the inspection seal 10 of the first embodiment and the configuration of the modification of the first embodiment. Therefore, it is possible to carry out these configurations in combination with each other.

10 ... Inspection seal, 11 ... Base film, 11F, 14F, 15F, 17F ... Front side, 11R, 14R, 15R, 17R ... Back side, 12 ... Coordinate grid, 12A, 12B ... Grid line, 12A1 ... First grid line, 12A2 ... 2nd grid line, 12B1 ... 1st division, 12B2 ... 2nd division, 12C ... position marker, 13 ... separate film, 14 ... protective film, 15 ... fluidized bed, 16 ... label, 17 ... adhesive layer.

Claims (12)

An inspection sticker used for diagnostic imaging using microwaves.
Equipped with a base film that has a scan index and can be attached to the inspection target,
An inspection seal having a tensile elongation at break of 130% or more and a 100% elongation / tensile strength of 4 N / cm or less in the base film. A fluidized bed composed of an aliphatic hydrocarbon that transmits microwaves more than water, and has a viscosity that allows the base film to be attached to the inspection target, and is laminated on the base film. The inspection seal according to claim 1, further comprising a layer. The inspection seal according to claim 2, wherein the shear viscosity of the fluidized bed at 30 ° C. and the shear viscosity defined in JIS Z 8803: 2011 is 1000 mPa · s or more and 200,000 mPa · s or less. The inspection seal according to claim 2 or 3, wherein the fluidized bed is formed of at least one selected from the group consisting of paraffin, squalane, and selecin. Further provided with an adhesive layer laminated on the base film,
The thickness of the adhesive layer is 5 μm or more and 25 μm or less.
In the inspection seal, in the laminate of the base film and the adhesive layer,
Moisture permeability as defined in JIS Z 0208 is, at 40 ° C. and 90% relative humidity conditions, inspection seal according to claim 1 is 750g ^/ m 2 · day or more. An inspection sticker used for diagnostic imaging using microwaves.
A base film that has an index to guide the position of the scan in the inspection target,
The adhesive layer laminated on the base film and having a thickness of 5 μm or more and 25 μm or less is provided.
In the inspection seal, the tensile elongation at break specified in JIS K 7127 is 130% or more, and the 100% elongation tensile stress is 10 MPa or less in the laminate of the base film and the adhesive layer. .. In the laminate of the adhesive layer and the base film, moisture permeability as defined in JIS Z 0208 is, 40 ° C. and at a relative humidity of 90% for, according to claim 6 is 750g ^/ m 2 · day or more Inspection seal. The base film has a pair of surfaces facing each other, and one of the pair of surfaces is a guide surface on which the index is printed.
The inspection seal according to claim 6 or 7, wherein the adhesive layer covers the guide surface. A separate film that is detachably laminated on the surface of the base film opposite to the guide surface, and
A protective film that is detachably laminated on the surface of the adhesive layer opposite to the surface in contact with the base film is further provided.
The inspection according to claim 8, wherein the total light transmittance defined in JIS K 7361-1 is 30% or more in the portion of the separate film, the base film, and the laminate of the adhesive layer excluding the index. Seal for. The index is a coordinate grid including a plurality of grid lines extending along the scanning direction and lining up along a direction intersecting the scanning direction, and in the plurality of grid lines, the grid line of the first color and the grid line. The inspection sticker according to any one of claims 1 to 9, wherein grid lines of a second color different from the first color are alternately arranged. The inspection sticker according to claim 10, further comprising a sign indicating a predetermined coordinate in the coordinate grid. The base film is made of polyurethane resin and
The inspection according to any one of claims 1 to 11, wherein the polyurethane resin contains at least one selected from the group composed of an ether-based polyurethane resin, an ester-based polyurethane resin, and a carbonate-based polyurethane resin. sticker.