JP2020078296A - Food composition - Google Patents

Abstract

To provide a food composition in which a metal oxide-containing powder (component A) generating hydrogen by being brought into contact with water, and an oxide of such as a transition metal, or a salt (component B) of such as a transition metal can be brought into contact with water in the body by combining the two components.SOLUTION: A food composition contains a metal oxide-containing powder (component A) generating hydrogen by being brought into contact with water, and a metal oxide powder and/or a metal salt (component B). The food composition is such that: the component A contains at least two kinds of metal oxides having a normal electrode potential smaller than that of Cu; the metal oxide in the component B is at least one kind of metal oxide selected from the group consisting of transition metals and the group 12 elements; and the metal salt in the component B is at least one kind of metal salt selected from the group consisting of transition metals and the group 12 elements.SELECTED DRAWING: None

Description

  The present invention relates to a food composition containing a metal oxide-containing powder that generates hydrogen upon contact with water, and a specific metal oxide powder and/or a specific metal salt.

  Patent Document 1 discloses a metal oxide-containing powder that is contacted with water to generate hydrogen.

JP, 2013-212498, A

The metal oxide-containing powder disclosed in Patent Document 1 is a powder containing a metal oxide obtained by partially oxidizing a metal powder that generates hydrogen (H ₂ ) upon contact with water. When the contained powder is brought into contact with water in the body, hydrogen having a small bubble diameter is generated, and active oxygen (superoxide anion (O ₂ ⁻ ), singlet oxygen ( ¹ O ₂ ), hydrogen peroxide (H ₂ ) existing in the body is generated. O ₂ ), hydroxyl radical (.OH))), and can particularly contribute to deactivating the hydroxyl radical.

  The present invention focuses on the function of a superoxide anion scavenging enzyme (superoxide dismutase (SOD)) that rapidly inactivates a superoxide anion in the presence of a transition metal or the like, and a metal oxide that generates hydrogen in contact with water. An object of the present invention is to provide a food composition in which an oxide such as a transition metal or a salt such as a transition metal (component B) is further used in combination with the contained powder (component A) so that these two components can come into contact with water in the body. .

The present invention is
A food composition comprising a metal oxide-containing powder (component A) that generates hydrogen upon contact with water, and a metal oxide powder and/or a metal salt (component B),
The component A contains an oxide of at least two kinds of metals having a standard electrode potential smaller than that of Cu,
The metal oxide in the component B is an oxide of at least one metal selected from the group consisting of transition metals and Group 12 elements,
The metal salt in Component B is a food composition which is a salt of one or more metals selected from the group consisting of transition metals and Group 12 elements.
Hereinafter, one or more metals selected from the group consisting of transition metals and Group 12 elements are referred to as “transition metals and the like”.

  According to the present invention, a metal oxide-containing powder (component A) that generates hydrogen upon contact with water is further combined with an oxide and/or salt of transition metal (component B), and these two components are It is possible to provide a food composition capable of contacting water in the body.

It is the residual rate of O ₂ ⁻ (superoxide anion) of the test sample A. It is the residual rate of O ₂ ⁻ (superoxide anion) of the test sample A/B. It is the residual rate of OH radicals of the test sample A. It is the residual rate of OH radicals of the test sample A/B. It is a lipid peroxide production rate of the test sample A. It is a lipid peroxide production rate of the test sample A/B.

[Component A]
The component A in the present invention is a metal oxide powder that generates hydrogen upon contact with water, and contains at least two kinds of metal oxides having a standard electrode potential smaller than that of Cu.

The component A can be obtained by oxidizing the powder of the metal X which produces hydrogen by contacting with water.
However, since it is difficult to generate hydrogen when the powder of the metal X is completely oxidized, it is preferable that the powder is not completely oxidized (hereinafter, complete oxidation is referred to as partial oxidation).
A suitable manufacturing method is illustrated below.

(1) Metal X
As the at least two kinds of metals X having a standard electrode potential smaller than the standard electrode potential of _Cu (hereinafter also referred to as “V _Cu ”) in the component A, hydrogen generation by contact with water of the component A (hereinafter referred to as “hydrogen generation”). From the standpoint of "property"), the standard electrode potential is smaller than V _Cu , preferably 3 or more, more preferably 4 or more, further preferably 5 or more, further preferably 7 or more, further preferably 10 or more. More preferably, it is 12 or more kinds of metals, and it is more preferable to combine Cu with these metals.

As the metal X in the component A, from the viewpoint of hydrogen generation,
One or more kinds of metal X ₁ selected from metals having a standard electrode potential of -2,000 or less;
One or more kinds of metal X ₂ whose standard electrode potential is selected from more than -2,000 and less than 0.600,
A combination of metals selected from each of one or more kinds of metals X _{3 having} a standard electrode potential of more than -0.600 and less than V _Cu (for example, in the case of two kinds, a combination of metals X ₁ and X ₂ , a metal X ₁ And X ₃ or the combination of metals X ₂ and X ₃ and, in the case of 3 kinds, the combination of metals X ₁ , X ₂ and X ₃ ) are preferable, and it is more preferable to further combine Cu with these combinations.

From the viewpoint of hydrogen generation, when the metals X ₁ , X ₂ and X ₃ are combined, 100 parts by weight of the metal X _i (i=1 or 2) having one standard electrode potential is added next to the metal X _i . The metal X _j having a high standard electrode potential is preferably 10 to 25 parts by weight, more preferably 15 to 20 parts by weight.

When using the metal X ₁ and the metal X ₂ , 100 parts by weight of the metal X ₁ is used.
The metal X ₂ is preferably 10 to 25 parts by weight, more preferably 15 to 20 parts by weight.

When all the metals X ₁ , X ₂ and X ₃ are used,
For 100 parts by weight of metal X ₁ ,
The metal X ₂ is preferably 10 to 25 parts by weight, more preferably 15 to 20 parts by weight,
The metal X ₃ is preferably 1 to 6.25 parts by weight, more preferably 1.5 to 5 parts by weight.

As the metal X, it is preferable to select a metal contained as a mineral in the body,
More preferably, at least two or more metals selected from the group consisting of K, Ca, Na, Mg, Mn, Cr, Zn, Fe, Mo and Co, preferably three or more metals, more preferably four or more metals. More preferably, Cu is further combined with these combinations.

As the metal X, from the viewpoint of hydrogen generation and mineral content,
It is preferable that at least two or more metals selected from the group consisting of Mg, Zn and Fe, preferably three metals,
More preferably, at least two or more metals selected from the group consisting of K, Mg, Zn and Fe, preferably three or more metals, and more preferably four metals,
More preferably, at least two or more, preferably three or more, and more preferably four or more metals selected from the group consisting of K, Ca, Na, Mg, Al, Zn, and Fe,
More preferably at least Mg and Zn are included,
It is more preferable to combine Cu with these combinations.

  The half reaction and the standard electrode potential, which are the basis of the standard electrode potential of the target metal X, are represented by the numerical values in the table below.

In the production of the component A, from the viewpoint of stabilizing the hydrogen generating property and mineral content when partially oxidizing the powder of the metal X (or preferably a combination of Cu),
Partial oxidation may be performed by combining the metal X (or a combination of Cu) with one or more, preferably two or more, and more preferably three elements selected from the group consisting of V, Se and P. preferable.

  The metal X may be a commercially available pure metal, or may be derived from a natural mineral containing the metal X.

  Examples of the natural minerals containing the metal X include igneous rocks and/or contact metamorphic rocks in which a large amount of minerals are eluted when contacted with water or an organic acid, which is a suitable raw material of the component B described later.

(2) Metal X powder manufacturing process The metal X powder corresponds to a desired mesh using an atomizing method, a centrifugal force atomizing method, a plasma atomizing method, a rotating electrode method, a mechanical process method, a chemical process method, or the like. It can be manufactured with different dimensions.

  The metal X powder may be produced by ball milling natural minerals in a size corresponding to the desired mesh.

  Here, the "mesh" means the number of meshes 1 inch above the sieve composed of meshes woven with metal wires, and has the following relationship with the guideline of the maximum spherical diameter passing through the mesh.

The size of the powder that passes through the x-mesh screen is called "x-mesh",
The size of the powder that passes through the sieve of x mesh or more is referred to as "x mesh or more".

When partially oxidizing the powder of the metal X, from the viewpoint of hydrogen generation, the metal X is
The powder is preferably 80 mesh or more, more preferably 100 mesh or more, further preferably 500 mesh or more, further preferably 1000 mesh or more,
From the viewpoint of long-term hydrogen generation,
It is preferably a mixed powder of 100 to 3000 mesh,
More preferably, it is a mixed powder of 100-500 mesh mixed powder and 1000-3000 mesh mixed powder,
More preferably, it is a mixed powder of 100-200 mesh mixed powder and 1000-2000 mesh mixed powder.

In the case of the combination of the mixed powder of 100 to 500 mesh and the mixed powder of 1000 to 3000 mesh or the combination of the mixed powder of 100 to 200 mesh and the mixed powder of 1000 to 2000 mesh,
With respect to 100 parts by weight of the metal contained in the metal X forming the mixed powder of 100 to 500 mesh or the mixed powder of 100 to 200 mesh,
The metal contained in the metal X constituting the mixed powder of 1000 to 3000 mesh or the mixed powder 50 of 1000 to 2000 mesh 50 is preferably 50±15 parts by weight, more preferably 50±10 parts by weight, still more preferably 50±5 parts by weight. Parts by weight.

The mixed powder of 100 to 3000 mesh or the mixed powder of 100 to 200 mesh is preferably at least two or more metals selected from the group consisting of Mg, Zn and Fe, preferably three metals,
More preferably, at least two or more metals selected from the group consisting of K, Mg, Zn and Fe, preferably three or more metals, and more preferably four metals,
More preferably, at least two or more, preferably three or more, and more preferably four or more metals selected from the group consisting of K, Ca, Na, Mg, Al, Zn, and Fe,
More preferably at least Mg and Zn are included,
It is more preferable that Cu is combined with the mixed powder of the mixed powder of 1000 to 3000 mesh or the mixed powder of 2000 to 3000 mesh.

(3) Partial Oxidation Step of Metal X Powder The powder of the metal X described above is added to, for example, strongly electrolyzed acidic water (also referred to as strongly acidic electrolyzed water).
Preferably at 10 to 50° C. for 10 to 240 minutes,
More preferably 15 to 120 minutes at 15 to 40°C,
More preferably, partial oxidation is performed by immersing at 20 to 30° C. for 30 to 90 minutes.

  Strongly electrolyzed acidic water is an aqueous solution containing hypochlorous acid (HClO) as a main component, and strongly acidic generated on the anode side when sodium chloride is added to water as an electrolyte and electrolyzed through an ion exchange membrane. Is a highly acidic liquid having a pH=2 to 3 and a redox potential of 1000 mV or more and a strong oxidizing power.

  Strongly electrolyzed acidic water can be produced, for example, by a JIS B 8701 hypochlorous acid water generator.

  For the partial oxidation of the metal X powder, a liquid having an oxidizing power can be used in addition to the strongly electrolyzed acidic water. Perchloric acid; aqueous hydrogen peroxide solution; nitric acid; chlorine fluoride, bromine trifluoride, pentafluoride. Although halogen compounds such as bromine fluoride can be used, strong electrolyzed acidic water is preferable from the viewpoint of safety in food applications and the viewpoint of having a bactericidal action.

The partially-oxidized metal X powder was placed in an electric dryer,
It is preferably 80 to 200° C., more preferably 90 to 180° C., further preferably 110 to 150° C., preferably 1 to 36 hours, more preferably 3 to 24 hours, still more preferably 6 to 12 hours. A metal oxide-containing powder (hereinafter also referred to as “metal oxide-containing powder 1”) in which the dried metal X is partially oxidized is obtained.

(4) Metal oxide-containing powder alloy-plating step From the viewpoint of maintaining hydrogen generation stability as a food composition for a long time under atmospheric environment (hereinafter referred to as “stability”), metal oxide-containing powder It is preferable to subject 1 to the following processing.

To 100 parts by weight of the metal oxide-containing powder 1,
Preferably 50 to 99 parts by weight, more preferably 70 to 95 parts by weight, and even more preferably 80 to 90 parts by weight of an organic chelate compound,
The metal oxide-containing powder 2 is obtained by adding 1 to 50 parts by weight, more preferably 5 to 30 parts by weight, and further preferably 10 to 20 parts by weight of an electrolyte and stirring and mixing.

As an organic chelate compound, from the viewpoint of safety in food applications,
Preferably, containing at least one or more organic acids selected from the group consisting of citric acid, ascorbic acid, malic acid, malonic acid, EDTA,
More preferably, at least one organic acid selected from the group consisting of citric acid, ascorbic acid, malic acid, malonic acid,
More preferably, it contains citric acid and/or ascorbic acid.

As the electrolyte, from the viewpoint of safety in food applications,
Preferably, at least one ion selected from the group consisting of Na ⁺ , K ⁺ , Ca ²⁺ , Mg ²⁺ , Cl ⁻ , PO ₄ ^{3 −} , and HCO ₃ ⁻ is dissolved in water, such as NaCl. It is an inorganic/organic salt electrolyte that dissociates.

  As the electrolyte, an industrial grade one that is a synthetic product can be used, but a naturally derived one such as a natural salt can also be used.

  A mold 1 whose upper and lower surfaces are open and a plate 1 that can close the lower surface of the mold 1 are prepared, and the mold 1 is placed on the plate 1 and the upper surface of which is open to the atmosphere. A form A composed of 1 and 1 is obtained.

The materials of the plate 1 and the plate 2 described later, and the mold 1 and the mold 2 described later are
From the viewpoint of durability against the reaction of the metal oxide-containing powders 2 and 3 with the organic chelate compound, the electrolyte and water in the process of obtaining the metal oxide-containing powder 4 described later,
It is preferably one or more metals selected from the group consisting of noble metals, stainless steel, aluminum alloys, titanium alloys and nickel alloys, and more preferably stainless steel, aluminum alloys, titanium alloys and nickel in view of economic efficiency. One or more metals selected from the group consisting of alloys, more preferably stainless steel.

The sizes of the molds 1 and 2 are determined from the viewpoint of the uniformity of pressurization in the pressing step described later.
The width is preferably 20 to 500 mm, more preferably 30 to 300 mm, further preferably 50 to 150 mm,
The length is preferably 100 to 1000 mm, more preferably 200 to 700 mm, further preferably 300 to 500 mm,
The depth is preferably 1 to 20 mm, more preferably 2 to 15 mm, further preferably 3 to 10 mm, and the depth of the mold 2 is preferably 30 to 100% of the depth of the mold 1, more preferably 50 to 10. 90%, more preferably 60 to 80%.

  The size of the plates 1 and 2 is such that the width and length are 5 to 10% larger than the width and length of the molds 1 and 2 so that the lower surfaces of the molds 1 and 2 can be closed, and the thickness is about 1 to 3 mm. is there.

  The mold A is constructed by spraying water on the surface of the plate 1 with a spraying machine such as a sprayer and then placing the mold 1 thereon.

  The water to be sprayed is preferably purified water in which tap water is passed through a water purifier using activated carbon or the like (the same applies to the water used below), and when the plate 1 has the above-mentioned suitable dimensions, it is preferable. Is 1 to 10 g, more preferably 2 to 8 g, still more preferably 3 to 6 g.

  The metal oxide-containing powder 2 is filled in the form A to the extent of scraping.

  Water is sprayed on the surface of the metal oxide-containing powder 2 exposed on the open surface of the mold by a spraying machine such as a sprayer.

  The amount of water to be sprayed is preferably 1 to 10 g, more preferably 2 to 8 g, still more preferably 3 to 6 g when the plate 1 has the above-mentioned suitable dimensions.

  After spraying water on the exposed surface of the metal oxide-containing powder 2 of the mold A, the mold A is placed in an indoor environment (temperature is preferably 25±4° C., more preferably 25±2° C., further preferably 25±2° C.). 1° C., relative humidity is preferably 65±5%, more preferably 65±3%, even more preferably 65±1%), preferably 6 to 48 hours, more preferably 12 to 36 hours, more preferably 18 The metal oxide-containing powder 3 swollen by standing for -30 hours is obtained.

  Due to the above-mentioned aging of the metal oxide-containing powder 2, the citric acid and the salt absorb water to react with the metal powder, and the metal powder is melted while generating heat and hydrogen gas, and the whole metal is in the form of an alloy plate. Oxide-containing powder 3 is obtained. Since the metal oxide-containing powder 3 expands due to bubbles generated inside due to generation of heat and hydrogen gas, it is replaced with a mold 2 having a size larger than that of the mold 1.

Instead of spraying water on the surface of the metal oxide-containing powder 2 exposed on the upper surface of the mold A, the mold A is placed in a constant temperature and humidity chamber,
The temperature is preferably 25±4° C., more preferably 25±2° C., further preferably 25±1° C.,
The relative humidity is preferably 80 to 100%, more preferably 90 to 100%, still more preferably 95 to 100%,
The swelled metal oxide-containing powder 3 is obtained by preferably standing for 7 to 30 days, more preferably 10 to 20 days, and further preferably 14 to 16 days.

  The mold 1 is removed, and the mold 1 is replaced with a mold 2 having the same depth as that of the mold 1 and a large area. The mold 1 is composed of the plate 1 and the mold 2, and the metal oxide-containing powder 3 opens the mold 2. The mold B inserted in the state exposed above the surface is obtained.

The plate 2 is placed on the metal oxide-containing powder 3 exposed from the mold B in a constant temperature and humidity room, and in an indoor environment,
While hot pressing from both the plate 1 side and the plate 2 side,
After standing at 50 to 200° C. for 15 minutes to 6 hours, more preferably at 60 to 150° C. for 30 minutes to 4 hours, and further preferably at 70 to 100° C. for 1 to 2 hours,
With the press on without heating
Preferably 25±4° C., more preferably 25±2° C., even more preferably 25±1° C.,
It is preferably left to stand for 12 to 36 hours, more preferably 16 to 32 hours, and further preferably 20 to 28 hours to obtain an alloy plate-shaped metal oxide-containing powder 4.

  In the hot pressing step, the hydrogen gas in the metal oxide-containing powder 3 is removed, and a more complicated redox reaction proceeds in the metal oxide-containing powder 3 to form an alloy plate-shaped metal oxide-containing powder 4. .

  As the heating press, for example, an NF single-action compression molding machine manufactured by Shindo Metal Industry Co., Ltd. can be used.

(5) Re-grinding step of alloy plate-shaped metal oxide-containing powder The alloy plate-shaped metal oxide-containing powder 4 taken out of the mold B is taken out in a drying chamber.
The temperature is preferably 25±4° C., more preferably 25±2° C., even more preferably 25±1° C.,
The relative humidity is preferably 30 to 70%, more preferably 35 to 65%, further preferably 40 to 55%,
After standing for 1 to 12 hours, more preferably 2 to 6 hours, and further preferably 3 to 5 hours,
The alloy plate-shaped metal oxide-containing powder 4 is preferably cut into 1 to 30 mm, more preferably 3 to 20 mm, further preferably 5 to 15 mm square in a plan view to form a tile,
Tile-shaped in an indoor environment, preferably still for 3 hours to 20 days, more preferably 1 to 10 days, still more preferably 2 to 5 days (more preferably still until the cut surface becomes dark) A metal oxide-containing powder 5 of is obtained.

  The tile-shaped metal oxide-containing powder 5 is crushed and sieved with a ball mill or the like in an indoor environment to obtain a metal oxide-containing powder (component A) having a desired size.

The size of the metal oxide-containing powder (component A) is preferably stepwise,
Preferably 100±50 mesh, more preferably 100±30 mesh, more preferably 100±10 mesh powder 1,
Preferably 300±100 mesh, more preferably 300±50 mesh, more preferably 300±30 mesh powder 2,
Preferably 700±300 mesh, more preferably 700±250 mesh, more preferably 700±200 mesh powder 3,
Preferably 2000±1000 mesh, more preferably 2000±500 mesh, more preferably 2000±200 mesh powder 4,
The weight ratio (powder 1/powder 2/powder 3/powder 4) is
Mixing is preferably 2 to 20/20 to 40/20 to 40/20 to 40, more preferably 5 to 15/25 to 35/25 to 35/25 to 35.

  The metal oxide-containing powder (component A) is further left to stand in an indoor environment for preferably 1 to 24 hours, more preferably 2 to 12 hours, and further preferably 3 to 6 hours, and packaged in a desired form.

[Component B]
The component B is a transition metal oxide or a transition metal salt capable of supplying the transition metal and the like required for SOD that rapidly deactivates the superoxide anion in the body.
The component B is not a metal oxide in a mode of generating hydrogen by contacting with water.

Since the transition metal oxide and/or the transition metal salt in the component B act in the body,
Preferably, an oxide and/or salt such as a transition metal existing in the body as a mineral,
More preferably, it is an oxide and/or a salt of at least one transition metal selected from the group consisting of Sc, Ti, V, Cr, Mn, Fe, Co, Ni, Cu and Zn,
More preferred are oxides and/or salts of at least one transition metal selected from the group consisting of Mn, Fe, Cu and Zn.
As the transition metal salt, silicate and/or carbonate is preferable.

  The component B can be obtained as follows.

(Form B1 of component B)
Oxides of transition metals and the like are contained in large amounts in igneous rocks and/or contact metamorphic rocks that elute many kinds of minerals when they come into contact with water or organic acids, and these igneous rocks and/or contact metamorphic rocks are crushed into fine powders. As a result, the component B, which is a powder (form B1) of a transition metal oxide and/or a transition metal salt, can be obtained.

(Form B2 of component B)
From the obtained transition metal hydroxide, etc., by separating and drying a liquid fraction from the transition metal etc. oxide and/or transition metal etc. salt containing slurry obtained by contacting the transition metal etc. element containing solution with a basic solution. The powder B (form B2) of component B can be obtained by pulverizing the oxide of transition metal produced by firing the dried product.

(Form B3 of component B)
The transition metal etc. and/or salt containing transition metal etc. (form B3) obtained by contacting the solution containing the element such as transition metal with the basic solution can be used as the component B as it is.

(Manufacturing method of form B1)
Form B1 is, specifically, excavating the original soil or rock containing the igneous rock and/or contact metamorphic rock, and the excavated original soil or rock is, for example, crushed, sieved, or classified, and the igneous rock and /Or contact metamorphic rocks are selected, the selected igneous rocks and/or contact metamorphic rocks are crushed, and have a nominal mesh opening according to JIS Z 8801-1, and preferably pass through a sieve of 38 to 850 µm, more preferably 38 to Passing through a 500 μm sieve, more preferably passing through a 38 to 250 μm sieve, further preferably passing through a 38 to 125 μm sieve, further preferably passing through a 38 to 63 μm sieve, and further preferably Pulverize to a degree that it will pass through a 38-53 μm sieve.

The contact metamorphic rocks that can be used as the raw material for the component B are metamorphosed from existing rocks due to heat and pressure of magma,
Crystalline limestone typified by marble, which was created by the contact metamorphism of limestone.
A skarn mainly composed of calcium and silicon, which is formed when the magma comes into contact with limestone and the components of the magma (silicon, iron, aluminum, etc.) react with the components of limestone (calcium),
It is possible to use hornfels and the like in which rocks other than limestone have undergone contact metamorphism.

  Among the contact metamorphic rocks, hornfels is preferable from the viewpoints of the number of types of minerals that are considered to be useful for the human body to be eluted by the organic acids described later and the low uranium content (safety).

Hornfels is a contact metamorphic rock with the following chemical composition:
(1) SiO ₂ is preferably 55 to 85 mass %, more preferably 60 to 75 mass %, further preferably 65 to 75 mass %;
(2) Al ₂ O ₂ is preferably 5 to 25% by mass, more preferably 10 to 20% by mass;
(3) Fe ₂ O ₂ is preferably 1 to 10% by mass, more preferably 1 to 5% by mass;
(4) TiO ₂ is preferably 0.1 to ₂ % by mass, more preferably 0.1 to 1% by mass;
(5) CaO is preferably 1 to 10% by mass, more preferably 1 to 5% by mass;
(6) MgO is preferably 1 to 10% by mass, more preferably 1 to 5% by mass;
(7) Na ₂ O is preferably 1 to 10% by mass, more preferably 2 to 6% by mass;
(8) K ₂ O is preferably 1 to 10% by mass, more preferably 1 to 5% by mass;
(9) MnO is preferably 0.01 to 1% by mass, more preferably 0.01 to 0.1% by mass;
(10) Ignition loss (Ig. Loss) is preferably 1 to 5% by mass, more preferably 1 to 3% by mass.

Examples of hornfels include muddy hornfels in which mudstone has been contact-modified, siliceous hornfels in which chert has been contact-modified, and sandstone hornfels in which sandstone has been contact-modified.
From the viewpoint of the number of types of minerals that are considered to be useful for the human body to be eluted by the organic acids described below and the low uranium content (safety), preferably sandstone hornfels composes the Shimanto Belt Formation of Japan. Sandstone hornfels derived from marine sedimentary rocks, more preferably Oita prefecture or southern Kyushu (preferably Kagoshima prefecture or Miyazaki prefecture), more preferably Oita prefecture or Miyazaki prefecture.

  For example, the sandstone hornfels collected at the border between Oita and Miyazaki prefectures are among the minerals useful for the human body, in addition to compounds containing major mineral elements such as magnesium oxide, aluminum oxide, ferric oxide, and potassium oxide. It contains trace metal elements such as vanadium, rubidium, titanium and zirconium, and radioactive rare earth elements such as uranium, thorium, lanthanum, lutetium and erbium, which are difficult to collect in the rocks.

  For example, according to the analysis results by the Oita Prefectural Industrial Science and Technology Center, the sandstone hornfels collected at the prefectural border between Oita Prefecture and Miyazaki Prefecture have the composition (oxide conversion) shown in Table 3.

(Method of manufacturing forms B2 and B3)
The igneous rock and/or contact metamorphic rock powder produced by the production method of form B1 is directly mixed with an organic acid or an aqueous solution thereof which can be used as a food additive, and an elution aqueous solution mixture containing minerals (hereinafter referred to as “containing component B”). (Also referred to as an “aqueous solution”) can be used as form B2, and the powder obtained by pulverizing the concentrated dried product can be used as form B3.

  The organic acid used in the elution step is preferably one that can be used as a food or food additive such as acetic acid.

The organic acid that can be used as a food additive is, for example, an organic acid that is approved as a food additive by a governmental agency that manages the safety of food additives in Japan.
According to the Ministry of Health, Labor and Welfare website (http://www.mhlw.go.jp/stf/seisakunitsuite/bunya/kenkou_iryou/shokuhin/syokuten/index.html) as of December 1, 2015, the Ministry of Health, Labor and Welfare The use of "additives", "existing additives", "natural flavors" and "general food additives" (about 100 items) as food additives is permitted.

As an organic acid approved for use as a food additive, for example,
The list of designated additives specified by the Ministry of Health, Labor and Welfare (Appendix 1 of the regulation) (revised September 18, 2015)
Adipic acid, L-ascorbic acid (also known as vitamin C), benzoic acid, erythorbic acid (also known as isoascorbic acid), citric acid, gluconic acid, L-glutamic acid, succinic acid, fatty acids, oxalic acid, DL-tartaric acid (also known as dl) -Tartaric acid), L-tartaric acid (also known as d-tartaric acid), sorbic acid, nicotinic acid (also known as niacin), lactic acid, glacial acetic acid, fumaric acid, propionic acid, hexanoic acid (also known as caproic acid), folic acid, butyric acid, DL- Malic acid (also known as dl-malic acid) and the like,
The list of existing additives includes L-aspartic acid, 5'-adenylic acid, alginic acid, isoalpha-bitter acid, itaconic acid, oligogalacturonic acid, higher fatty acid, 5'-cytidylic acid, hyaluronic acid, phytic acid, ferulic acid. Acids, gallic acid, mevalonic acid and the like are mentioned.

Organic acids, preferably used organic acids that have been approved for use as these food additives, from the viewpoint of dissolution efficiency and taste of the drinking water composition,
Preferably, at least one compound selected from the group consisting of citric acid, L-tartaric acid, fumaric acid, DL-malic acid, succinic acid, lactic acid, acetic acid, gluconic acid and L-ascorbic acid,
More preferably, at least one compound selected from the group consisting of citric acid, acetic acid and L-ascorbic acid,
More preferred is citric acid.

  From the viewpoint of easy solubility in water, it is preferable to use citric acid hydrate (preferably monohydrate) as citric acid.

  In the elution step, the igneous rock and/or contact metamorphic rock powders described above are eluted using the organic acid or the aqueous solution thereof as a solvent to obtain an elution aqueous solution mixture.

  The pH of the solvent is preferably 1 to 4, more preferably 1 to 3, and still more preferably 1 to 2 from the viewpoint of elution efficiency.

  The organic acid can be used as long as it is liquid, but it is preferable to use an aqueous solution of the organic acid from the viewpoint of elution efficiency and pH control.

  The pH of the organic acid aqueous solution can be adjusted depending on the degree of dilution with water, or can be separately adjusted by adding an organic acid.

  Dilution water when using an aqueous solution of an organic acid may be tap water, distilled water, ion-exchanged water, or the like, but the hardness of tap water is preferably 0 to 0 from the viewpoint of elution efficiency and ease of water quality management. It is 120 mg/L, more preferably 1-110 mg/L, still more preferably 10-100 mg/L, further preferably 20-90 mg/L, further preferably 30-80 mg/L.

  Distilled water and/or ion-exchanged water is preferably used as the dilution water when using the aqueous solution of the organic acid, from the viewpoint of elution efficiency and water quality control.

  From the viewpoint of elution efficiency, the temperature of the solvent is preferably 10 to 90°C, more preferably 20 to 90°C, further preferably 40 to 90°C, further preferably 60 to 90°C, further preferably 70 to 90°C. is there.

  From the viewpoint of eluting a sufficient amount of minerals, the elution time is preferably 0.5 to 24 hours, more preferably 1 to 18 hours, further preferably 2 to 10 hours, further preferably 2 to 6 hours, The higher the temperature of the solvent, the shorter the elution time can be. The preferable elution time of the elution system containing the contact metamorphic rock powder and the solvent is preferably within the above range.

  The elution time is preferably 0.5 to 24 hours, more preferably 5 to 24 hours, and further preferably 10 to 24, from the viewpoint of eluting a sufficient amount of minerals in an elution system containing igneous rock powder and a solvent. The time is more preferably 15 to 24 hours, and the higher the temperature of the solvent, the shorter the elution time can be.

  In the elution system containing the powder of the igneous rock and/or the contact metamorphic rock and the solvent, the amount of the solvent is preferably 100 to 10,000 parts by mass, more preferably 200 to 100 parts by mass with respect to 100 parts by mass of the powder of the igneous rock and/or the contact metamorphic rock. 5000 parts by mass, more preferably 300 to 3000 parts by mass, further preferably 300 to 1500 parts by mass, further preferably 500 to 1500 parts by mass, further preferably 500 to 1000 parts by mass.

  The elution system is preferably stirred from the viewpoint of elution efficiency. For example, when the stirring blade is rotated and stirred, preferably 1 to 100 rpm, more preferably 5 to 60 rpm, still more preferably 10 to 30 rpm. is there.

[Food composition of the present invention]
The present invention is a food composition containing component A and component B, and adjusts the five sense characteristics such as taste, aroma and color, storage stability, pH, viscosity, specific gravity, surface tension, aqueous solution characteristics such as hardness and the like. Food additives for can be added as additives.
The present invention includes the following embodiments depending on the forms of the component A and the component B.

<<Embodiment example 1>>
A food composition, wherein component A is a powder (kit component A), component B is a powder or solution (kit component B), and the kit comprises kit component A and kit component B.

  For example, a food composition kit comprising a container A filled with powdered ingredient A and a container B filled with ingredient B of form B1, B2 or B3.

  The container A and the container B may be foldable packaging of paper, or containers made of paper, wood, plastic, or ceramics such as glass, but are sealed except when in use so that the component A and the component B are hard to contact with the atmosphere. Is preferred.

Examples of the method of ingestion into the body include the following methods:
(1) Taking appropriate amounts of the components A and B from the containers A and B and ingesting them into the body as they are; or
(2) If necessary, pour into the body with water or an organic acid that can be used as a food additive or an aqueous solution thereof to eat.

<<Embodiment example 2>>
A food composition kit comprising a water-soluble capsule A filled with a powder component A and a water-soluble capsule B filled with a powder component B.

Examples of the method of ingestion into the body include the following methods:
An appropriate amount of water-soluble capsule A and an appropriate amount of water-soluble capsule B are poured into water and eaten together with water or an organic acid that can be used as a food additive or an aqueous solution thereof.

<<Embodiment example 3>>
The weight ratio (A/B) of powdered component A to powdered (preferably Form 1 or 3) component B is preferably 20/80 to 80/20, more preferably 30/70 to 40/60, and A food composition comprising a mixed powder of 35/65 to 45/55 of component A and component B, which is preferably encapsulated in a water-soluble capsule.

  As a method of ingestion into the body, a water-soluble capsule is poured into the body along with an appropriate amount of water for eating.

In the food composition of the present invention, a metal oxide-containing powder (component A) that generates hydrogen upon contact with water is further used in combination with a transition metal oxide and/or a transition metal salt (component B). Since the composition is a food composition whose components can contact water in the body,
The component A comes into contact with water in the body to generate hydrogen having a small bubble diameter, and active oxygen existing in the body (superoxide anion (O ₂ ⁻ ), singlet oxygen ( ¹ O ₂ ), hydrogen peroxide (H ₂ O ₂ ), hydroxyl radical (.OH))), in particular, helps to deactivate the hydroxyl radical,
The function of superoxide anion scavenging enzyme (superoxide dismutase (SOD)) that rapidly inactivates the superoxide anion in the presence of the transition metal or the like due to the component B coming into contact with water and the transition metal or the like flowing out into the water is more effective. It can be expected to be activated.

  Therefore, the food composition of the present invention is highly effective in controlling the generation of active oxygen in the body (for example, aging, carcinogenesis, lifestyle-related diseases). In addition, since it is possible to provide an in-vivo environment in which two types of strong active oxygen are easily deactivated, it is possible to provide an in-vivo environment in which these situations are alleviated or the QOL decrease caused by these situations is suppressed.

  For example, the food composition of the present invention contributes to the supply of trace minerals necessary for the enzymes involved in the production of white blood cells, and therefore occurs in a large amount when an anticancer agent is taken, and not only the attacking action of cancer cells It is expected that the inactivation of excess active oxygen, which causes the side effect of white blood cell count reduction, will be appropriately promoted, the recovery of white blood cell count will be promoted more than ever, and the QOL of cancer patients will be improved.

  Similarly, the food composition of the present invention is expected to suppress poor physical condition due to aging and/or lifestyle-related diseases, or due to food intake that may cause aging and/or lifestyle-related diseases such as alcohol drinking.

"Example"
Component A is a powder (kit component A), component B is a powder or solution (kit component B), and a food composition that is a kit containing kit component A and kit component B is in solution after ingestion into the body. The effect of the food composition of the present invention was verified by assuming the above embodiment.

A. Test Raw Material (1) Component A
(1-1) Metal powder 2 g each of 100-mesh potassium, copper, and calcium;
1g each of 100 mesh powder of molybdenum, vanadium, nickel, manganese, selenium, sodium, cobalt, lithium, phosphorus, chromium
A total of 13 kinds of metal powders are subjected to a bowl roll pulverizer and pulverized to 1000 to 3000 mesh to obtain metal powder.

(1-2) Oxidation After mixing 70 g of 100-mesh magnesium, 12 g of zinc, 2 g of iron, and the above metal powder with a blender, oxidation is performed with super-oxidized water for sterilization, and then water is removed. The super-acidic water used in this example has a pH of 2.8 and an ORP of 1000 mV or higher (vs. Ag/AgCl), and a strong acid water generator (product name: Santron) manufactured by Koshin Co., Ltd. Generated.

(1-3) Ionized mixture 85 g of citric acid and 7.5 g of natural salt were mixed with a blender, to which the metal powder sterilized and oxidized in (1-3) above was added, and further mixed with a blender to ionize and mix. The body.
The salt is known to chelate calcium, vitamins and the like.

(1-4) Formwork and stainless steel plate One stainless steel formwork 1 (length x width x height = 100 mm x 400 mm x 7 mm),
1 formwork 2 (110mm×420mm×5mm),
Prepare two stainless steel plates 3 (130 mm x 440 mm x 1 to 3 mm).

(1-5) Alloy Plate Water is sprayed onto the surface of the stainless steel plate 3 by spraying the water, and the mold 1 is placed on it. In that state, the ionized mixture is put in the mold 1, water is sprayed on the surface of the ionized mixture by spraying, and the mixture is left as it is for 24 hours. As a result, the citric acid and the salt contained in the ionized mixture absorb water to react the magnesium powder, and the magnesium powder is dissolved. At this time, the molten magnesium is bonded so as to enclose the other 15 kinds of metal powders while generating heat and hydrogen gas, thereby forming an alloy plate. Since bubbles are generated inside the alloy plate due to the generation of heat and hydrogen gas, the alloy plate expands. Therefore, the mold 2 is replaced with a mold 2 having a size larger than that of the mold 1.

(1-6) Redox reaction Another stainless steel plate 3 is placed on the alloy plate and pressed for about 1 hour while applying heat of about 100°C to 200°C from above and below the alloy plate and the stainless steel plate 3. As a result, the bubbles in the alloy plate are almost eliminated. After that, if heating is stopped and the material is left pressed for about 24 hours, the generation of hydrogen gas causes the exchange of electrons between the metal powders in the alloy plate, that is, the redox reaction.

(1-7) Drying By the end of the generation of hydrogen gas, the water content is almost gone, and a relatively soft alloy plate is obtained. This is put in a drying chamber and dried for about 3 to 4 hours.

(1-8) Oxidation reaction The alloy plate taken out from the drying chamber is cut into about 10 mm square and left to stand for about 3 days to proceed with the oxidation reaction.

(1-9) Mixed powder A 10 mm square alloy plate that has been left for about 3 days is finely crushed with a crusher to give a powder of about 100 mesh. This is passed through a sieve to take out about 10% of the 100-mesh powder, and the remaining powder is further pulverized to obtain a 300-mesh powder. This is passed through a sieve to take out about 30% of the powder of 300 mesh, and the remaining powder is further pulverized to give powder of about 900 mesh. This is passed through a sieve to take out approximately 30% of the powder of 900 mesh, and the remaining powder is made into 1000 to 3000 mesh with a bowl roll grinder. After that, these powders having different sizes are mixed with a blender to obtain a mixed powder.

(1-10) Compound A
The obtained mixed powder is allowed to continue to oxidize to form component A.

(2) Component A stock solution and test sample A
5 g of citric acid (Kishida Chemical Co., Ltd., food additive) is dissolved in 100 ml of pure water (Wako Pure Chemical Industries, Ltd., CAS No.7732-18-5), and 3 g of component A is dissolved in this.
After becoming a transparent liquid after 30 minutes, the black precipitate remaining on the bottom of the container is left as it is and the supernatant liquid is used as a stock solution of the component A solution.
A stock solution of the component A solution and its diluted solution with pure water were used as test sample A.

(3) Component B stock solution

(3-1) Raw material (3-1-1) Contact metamorphic rock: Sandstone hornfels powder having chemical composition shown in Table 3 (manufactured by Only Co., nominal mesh size 45 μm (325 mesh) sieve passed product)
(3-1-2) Organic acid: Citric acid monohydrate (Kishida Chemical Co., food additive grade)
(3-1-3) Water: Pure water (3-1-4) Organic acid aqueous solution: 500 g of water was added to 50 g of organic acid to prepare an organic acid aqueous solution having 9.1% by mass and pH=1.7.

(3-2) Elution conditions A 1000 ml beaker was filled with an organic acid aqueous solution (500 ml), 100 g of sandstone hornfels powder was added, the temperature was raised to 80°C, and stirring was performed at 10 to 20 rpm using a stirring rod, The solution obtained by elution under atmospheric pressure for 24 hours at 80° C. was used as a stock solution of the component B solution.

(4) Component A/B mixed solution and test sample A/B
The component A solution stock solution and the component B stock solution stock solution are mixed at a weight ratio of 1:1 to prepare a component A/B mixed solution stock solution.
A stock solution of the component A aqueous solution and its diluted solution with pure water were used as test samples A/B.

B. Test conditions (1) SOD-like activity acting superoxide anion (O ^2-) superoxide erasing ability dismutase (Superoxide dismutase, SOD) is measured as like activity.
SOD Assay Kit-WST (Cat No. S311, Dojindo, Japan) was used for the measurement of O ² -elimination ability.

(1-1) To a 96-well plate (Lot. 9107, Corning, USA), 20 μL of a test product or control, 200 μL of WST working solution, and 20 μL of Enzyme working solution were added. For the blank, Dilution buffer was used as an alternative to Enzyme working solution. Three wells were used for one treatment group.

(1-2) The 96-well plate was sealed with a plate seal (Cat No. 62-0891-48, WATSON, Japan), shaken at 270 rpm for 10 seconds, and incubated at 37°C for 20 minutes.

(1-3) After 20 minutes, the absorbance (OD ₄₅₀ ) at ₄₅₀ nm was measured using a microplate reader (SPARK (registered trademark) 10M, TECAN, Switzerland).

(1-4) test articles, the control OD ₄₅₀ of the test product O ₂ ^- residual ratio and O ₂ ^- the erase ratio was calculated by the following equation, O ₂ ^- was SOD-like activity rate of test articles erasure rate.
O ₂ ^- residual rate (%) = (S-SB ) / (C-CB) × 100
O ₂ ^- erasure rate (%) = {(C- CB) - (S-SB)} / (C-CB) × 100 = SOD -like activity rate (%)
C: OD _{450 of} control
CB: control blank OD ₄₅₀
S: OD _{450 of} test product
SB: Blank OD _{450 of} test product

(2) OH radical scavenging action The radical scavenging action of the test product against OH generated from hydrogen peroxide is measured.

(2-1) 50 μL of a test substance or control and 50 μL of 1.5 mM hydrogen peroxide (H ₂ O ₂ , CAS No. 7722-84-1, Wako, Japan) were added to a 1.5 mL tube. Purified water was used as a blank instead of 1.5 mM H ₂ O ₂ .

(2-2) The solutions were mixed using a vortex mixer and incubated at 37°C for 20 minutes.

(2-3) After 20 minutes, 1.49 mL of 100 mmol/L DA-64 (CAS No. 115871-19-7, Wako, Japan) and 0.5% Triton X-100 (CAS No. 9002-93-1, Sigma , USA) containing 0.1 mol/L PIPES (CAS No. 5625-37-6, Dojindo, Japan) 10 μL of the incubated solution was added to a 5 mL tube containing buffer solution, and the solution was mixed using a vortex mixer. Incubated at 0°C for 5 minutes.

(2-4) After 5 minutes, 200 μL of the solution incubated in the 96-well plate was added, and the absorbance at ₇₂₇ nm (OD ₇₂₇ ) was measured using a microplate reader.

(2-5) The OH radical residual rate and OH radical scavenging rate of the test product were calculated from the OD _{727 of the} test product and the control by the following formulas.
OH radical residual rate (%) = (S-SB)/(C-CB) x 100
OH radical scavenging rate (%) = {(C-CB)-(S-SB)}/(C-CB) x 100
C: control OD ₇₂₇
CB: control blank OD ₇₂₇
S: OD _{727 of} test product
SB: Blank OD _{727 of} test product

(3) Lipid Peroxide Production Inhibitory Action A conjugated diene produced by the oxidation of linoleic acid, which is one of unsaturated fatty acids, is measured.

(3-1) 10 mM Sodium Dodecyl Sulfate (SDS, CAS No.) containing 1200 μL of 0.26 mM linoleic acid (CAS No. 60-33-3, Wako, Japan) in a 1.5 mL tube (Cat No. 0030125150, Eppendorf, Germany) 151-21-3, Sigma, USA) solution, 15 μL of test article and control were added and the solution was mixed by sonication. PBS was used as a blank.

(3-2) Add 6 μL of 0.2% 2,2'-Azobis (2-methylpropionamidine) Dihydrochloride (AAPH,CAS No. 2997-92-4, Wako, Japan) solution to a 1.5 mL tube, and use sonication and vortex mixer. The solution was mixed by.

(3-3) 200 μL was collected in a UV-transmissive 96-well plate (Cat No. 8404, Thermo Fisher, USA), and the absorbance at ₂₃₃ nm (OD ₂₃₃ ) was measured using a microplate reader.
(3-4) The UV-transmissive 96-well plate was sealed with a plate seal and incubated at 50°C for 90 minutes.
(3-5) After 90 minutes, the UV transmissive 96-well plate was shaken at 270 rpm for 30 seconds, and then OD ₂₃₃ was measured using a microplate reader.
(3-6) The lipid peroxide production rate and the lipid peroxide production inhibition rate of the test product were calculated from the OD _{233 of the} test product and the control by the following formula.
Lipid peroxide production rate (%) = (S-SB)/(C-CB) x 100
Lipid peroxide production inhibition rate (%) = {(C-CB)-(S-SB)}/(C-CB) x 100
C: Control OD ₂₃₃
CB: control blank OD ₂₃₃
S: OD _{233 of} test product
SB: Blank OD _{233 of} test product

(4) Significant difference test For each test, a significant difference test was carried out for the control and the test article addition group by the corresponding t test. In both tests, the significance level was less than 5% on both sides (P<0.05, P<0.01, P<0.001).

C. Results (1) Test sample A
The test sample A was prepared by diluting the stock solution of the component A solution with pure water to 0.1%, 0.2%, 1%, 10%, 20% and 100% (stock solution of the component A solution).

(2) Test sample A/B
The component A/B solution stock solution was diluted with pure water to 0.1%, 0.2%, 1%, 10%, 20%, and 100% (component A solution stock solution) to prepare test samples A/B.

D. Effect of the Invention (1) The results shown in Tables 4 to 9 are compared in FIGS.
FIG. 1 shows the residual rate of O ₂ ⁻ (superoxide anion) in test sample A,
FIG. 2 shows the residual rate of O ₂ ⁻ (superoxide anion) in the test samples A/B,
FIG. 3 shows the residual rate of OH radicals of the test sample A,
FIG. 4 shows the residual rate of OH radicals of the test samples A/B,
FIG. 5 shows the lipid peroxide production rate of test sample A,
FIG. 6 is the lipid peroxide production rate of test sample A/B.

(2) O ₂ ⁻ (superoxide anion) residual ratio The test sample A, which is an aqueous solution of the component A, has an O ₂ ⁻ (superoxide anion) scavenging ability (small residual ratio) of 10% and 20%. , Was significantly expressed at a concentration of 100%,
The test sample A/B, which is an aqueous solution of the present invention (food composition containing components A and B), has a stock solution of 0.1%, 0.2%. At the concentrations of 1%, 2%, 10%, 20% and 100%, the scavenging ability of O ₂ ⁻ (superoxide anion) is significantly expressed,
The erasability is improved at each step as compared with the test sample A at the above concentration.

(3) OH Radical Residual Rate Test sample A, which is an aqueous solution of component A,
A constant OH radical scavenging ability (small residual rate) is significantly expressed at a concentration of 0.1 to 20%, and a particularly good OH radical scavenging ability is expressed at a stock solution of 100%.
The test sample A/B, which is an aqueous solution of the present invention (food composition containing components A and B),
Stock solution 0.1%, 0.2%. At the concentrations of 1%, 2%, 10%, 20% and 100%, OH radical scavenging ability (small residual rate) is significantly expressed,
The erasing ability is remarkably improved at the above concentration of each stock solution.

(4) Lipid Peroxide Production Rate Test sample A, which is an aqueous solution of component A,
At a concentration of 0.2 to 2% of the stock solution, a constant lipid peroxide inhibitory ability (small production rate) is significantly expressed, and at a stock solution of 10 to 100%, a particularly good lipid peroxide inhibitory ability is expressed.
The test sample A/B which is an aqueous solution of the present invention (food composition containing components A and B) is
Stock solution 0.1%, 0.2%. At the concentrations of 1%, 2%, 10% and 20%, the lipid peroxide inhibitory ability was significantly expressed,
The suppression ability is remarkably improved at the above concentration of each stock solution.

The good O ₂ ⁻ (superoxide anion) and OH radical scavenging ability of the present invention is considered to be a synergistic action of Component A and Component B.

The good lipid peroxide production-inhibiting ability of the present invention is such that cholesterol and neutral fat are oxidized by active oxygen to become a bad lipid peroxide. The hydroxyl radical, which is the strongest active oxygen in the living body, becomes
・OH+H ₂ =H ₂ O+・H
In the above, since it is reduced to water by the component A, it is considered that the production of lipid peroxide is suppressed.

  On the other hand, it is presumed that the component B suppresses the production of lipid peroxide by a completely different mechanism. In the A+B component system, suppression of lipid peroxide production by this completely different unknown mechanism is predominant.

From the above, the present invention has high scavenging ability for O ₂ − (superoxide anion) and OH radical (hydroxyl radical) having extremely high reactivity, which are generated by inflammation and metabolism of the human body, and further has high peroxidation. It is also expected to contribute to the suppression of lifestyle-related diseases such as cancer and aging by scavenging SOD activity, OH radicals (hydroxyl radicals), and suppressing lipid peroxides because of its excellent lipid suppressing ability.

Claims (5)

A food composition comprising a metal oxide-containing powder (component A) that generates hydrogen upon contact with water, and a metal oxide powder and/or a metal salt (component B),
The component A contains an oxide of at least two kinds of metals having a standard electrode potential smaller than that of Cu,
The metal oxide in the component B is an oxide of one or more metals selected from the group consisting of transition metals and Group 12 elements,
The food composition, wherein the metal salt in Component B is a salt of at least one metal selected from the group consisting of transition metals and Group 12 elements.   The food composition according to claim 1, wherein the component A is obtained by oxidizing a powder of a metal that generates hydrogen by contacting with water.   The food according to claim 1 or 2, wherein the component A is a powder (kit component A), the component B is a powder or a solution (kit component B), and the kit includes the kit component A and the kit component B. Composition.   The food composition according to claim 1 or 2, wherein the component B is a powder.   The food composition according to claim 4, wherein a mixed powder of the component A and the component B having a weight ratio A/B of the component A and the component B of 20/80 to 80/20 is encapsulated in a water-soluble capsule.