JP2020015768A - Agrochemical composition and pest control method - Google Patents

Abstract

To provide an agrochemical composition exhibiting high pest control effect on pest, safe to crop plants, and excellent in physical chemistry.SOLUTION: The agrochemical composition contains an agrochemical compound (a1) selected from a compound group A and an agrochemical compound (a2) selected from the compound group A, and a weight ratio of the agrochemical compound (a1) and the agrochemical compound (a2), agrochemical compound (a2)/agrochemical compound (a1), is 1/1,000 or less. The pest control method includes a process for applying the agrochemical compound (a1) selected from the compound group A and the agrochemical compound (a2) selected from the compound group A, and the weight ratio of the agrochemical compound (a1) and the agrochemical compound (a2), agrochemical compound (a2)/agrochemical compound (a1), is 1/1,000 or less.SELECTED DRAWING: None

Description

  The present invention relates to a pesticide composition and a method for controlling pests.

  Conventionally, pesticides have been used for the purpose of controlling pests, and many pesticide compounds are known as active ingredients of pesticides (see Patent Documents 1 and 2).

U.S. Pat. No. 6,537,948 International Publication No. WO 2017/065228

  An object of the present invention is to provide an agrochemical composition that exhibits a high control effect on pests, is safe for crops, and has excellent physicochemical properties.

The present inventor has found that an excellent pesticide composition can be obtained by combining a pesticide compound with a different pesticide compound at a weight ratio of 1/1000 or less.
The present invention includes the following [1] to [3].

[1] An agricultural chemical compound (a1) selected from the compound group A and an agricultural chemical compound (a2) selected from the compound group A, wherein the weight ratio of the agricultural chemical compound (a1) to the agricultural chemical compound (a2) is (A2) / A pesticide composition having a pesticide compound (a1) of 1/1000 or less.
[2] The weight ratio between the pesticide compound (a1) and the pesticide compound (a2) is 1/1000 to 1 / 1,000,000,000,000,000,000 for the pesticide compound (a2) / the pesticide compound (a1). The pesticidal composition according to [1].
[3] a weight ratio between the pesticide compound (a1) and the pesticide compound (a2), including a step of applying the pesticide compound (a1) selected from the compound group A and the pesticide compound (a2) selected from the compound group A; Is a pesticide compound (a2) / pesticide compound (a1) of 1/1000 or less.

  ADVANTAGE OF THE INVENTION According to this invention, it becomes possible to provide the pesticidal composition which demonstrates high control effect with respect to pests, is safe for crops, and has excellent physicochemical properties.

  The pesticidal composition of the present invention (hereinafter, referred to as the present composition) comprises, as an active ingredient of a main pesticide, a pesticide compound (a1) selected from the following compound group A (hereinafter sometimes referred to as a main drug substance). And a trace amount of an agrochemical compound (a2) (hereinafter, sometimes referred to as a minor drug substance) different from the agrochemical compound (a1) selected from the following compound group A.

Compound group A consists of the following pesticide compounds.
Herbicide compounds
2,3,6-TBA (2,3,6-trichlorobenzoic acid), 2,4-D, 2,4-DB, acetochlor (acetochlor), acifluorfen (acifluorfen), acronifen (aclonifen), ACN ( 2-amino-3-chloronaphthalene-1,4-dione), alachlor (alachlor), alidochlor (allidochlor), alloxydim (alloxydim), amethrin (ametryn), amicarbazone (amicarbazone), amidosulfuron, aminocyclo Pyracrol (aminocyclopyrachlor), aminocyclopyrachlor-methyl (aminocyclopyrachlor-methyl), aminopyralid (aminopyralid), amiprophos-methyl (amiprophos-methyl), amitrole (amitrole), anilofos (anilofos), ashram (asulam), atrazine (atrazine) ), Azafenidin, azimsulfuron, beflubutamid, benazolin-ethyl yl), bencarbazone (bencarbazone), benfluralin (benfluralin), benfresate (benfuresate), bensulfuron (bensulfuron), bensulfuron-methyl (bensulfuron-methyl), bensulide (bensulide), bentazon (bentazon), benthiocarb (benthiocarb), benzfen Dizone (benzfendizone), benzobicyclon (benzobicyclon), benzofenap (benzofenap), benzthiazuron (benzthiazuron), bialaphos (bialafosbialaphos), bicyclopyrone (bicyclopyrone), bifenox (bifenox), bispyribac (bixlozone) (bixlozone) , Bromacil, bromobutide, bromofenoxim, bromoxynil, bromoxynil-octanoate, butachlor, butafenasi (Butafenacil), butamifos (butamifos), buturerin (butralin), butroxydim (butroxydim), butyrate (butylate), cafenstrole (cafenstrole), carbetamide (carbetamide), carfentrazone (carfentrazone), carfentrazone ethyl (carfentrazone) -ethyl), chloromethoxyfen, chloramben, chloridazone, chlorimuron, chlorimuron, chlorimuron-ethyl, chlorobromuron, chlorotomuron, chloroxuron chloroxuron), chlorpropham, chlorsulfuron, chlorthal-dimethyl, chlorthiamide, chlorthiamid, sinidone, sinidon-ethyl, cinmethylin (cinmethyli) n), sinosulfuron, clethodim, clodinafop, clodinafop, clodinafop-propargyl, clomazone, clomazone, clomeprop, clopyralid, cloransulam, cloransulam Rhammethyl (cloransulam-methyl), cumyluron, cyanazine, cyclopyranil, cyclopyranil, cycloate, cyclopyrimorate, cyclosulfamuron, cyclosulfamuron, cycloxydim, cyhalofop (Cyhalofop), cyhalofop-butyl, daimuron, dalapon, dazomet, dazomet, desmedipham, desmethrin, desmetryn, di-allate, dicamba , Clovenil (dichlobenil), dicloprop (dichlorprop), dicloprop 2-ethylhexyl (dichlorprop-2-ethylhexyl), dicloprop butyl (dichlorprop-butotyl), dicloprop isooctyl (dichlorprop-isoctyl), dicloprop-methyl (dichlorprop- methyl), dicloprop P (dichlorprop-P), dicloprop P 2-ethylhexyl (dichlorprop-P-2-ethylhexyl), diclohop (diclofop), diclohopmethyl (diclofop-methyl), dicloslam (diclosulam), difenoxuron (difenoxuron) ), Difenzoquat, difenzoquat methyl sulfate (difenzoquat metilsulfate), diflufenican, diflufenzopyr, diflufenzopyr, diflufenzopyr-sodium, dimefuron, dimefuronate (Dimepip erate), dimethachlor, dimethametryn, dimethenamid, dimethenamid P (dimethenamid-P), dimepiperate, dinitramine, dinoseb, dinoterb, dinoterb , Diquat, diquat-dibromide, DSMA (disodium methylarsonate), dithiopyr, diuron, DNOC (2-methyl-4,6-dinitrophenol), esprocarb, esprocarb Fluralin (ethalfluralin), ethametsulfuron (ethametsulfuron), ethametsulfuron-methyl (ethametsulfuron-methyl), ethidimuron (ethidimuron), ethofumesate (ethofumesate), ethoxyfen-ethyl, ethoxysulfuronide, ethoxysulfuronide (Etobenzanid ), Fenoxaprop, fenoxaprop-ethyl, fenoxaprop-P, fenoxaprop-P, fenoxaprop-P-ethyl, fenoxasulfone, fen Quinotrione (fenquinotrione), fentrazamide, fenuron, fenuron M, flamprop-M, flazasulfuron, floraslam, florasulam, florpyrauxifen, florpyrauxifene benzyl (Florpyrauxifen-benzyl), fluazifop (fluazifop), fluazifop-butyl (fluazifop-butyl), fluazifop P (fluazifop-P), fluazifop-P-butyl (fluazifop-P-butyl), fluazolate (fluazolate), flucarbazone (flucarbazone), Flucetosulfuron, full Phenacet (flufenacet), flufenpyr (flufenpyr), flufenpyr-ethyl (flufenpyr-ethyl), flumetetsulam (flumetsulam), flumethoslam (flumetsulam), flumicrolac (flumiclorac), flumiclorac-pentyl, fluometuron ( fluometuron), fluoroglycofen-ethyl, flupoxam, flupropanate, flupropansulfuron, flupyrsulfuron, flupyrsulfuron-methyl-sodium, flurenol, Fluridone (fluridone), flurochloridone (flurochloridone), fluoxypyr (fluroxypyr), fluoxypyrbutomethyl (fluroxypyr-butometyl), fluoxypyreptyl (fluroxypyr-meptyl), flurtamone (flurtamone), fluthiacet (fluthiacet), Fluthiacet-methyl, fomesafen, fomesafen-sodium, foramsulfuron, fosamine, glufosinate, glufosinate-P, glufosinate-P (Glyphosate), halauxifen, halauxifen-methyl, halosafen, halosulfuron, halosulfuron-methyl, haloxyfop, haloxyfop et Tyl (haloxyfop-etotyl), haloxyfop-methyl, haloxyfop-P, haloxyfop-P-ethtyl, haloxyfop-P-methyl, haloxyfop-P-methyl, hexazinone ), Imazamethabenz, imaza Tavenzmethyl (imazamethabenz-methyl), imazamox (imazamox), imazapic (imazapic), imazapyr (imazapyr), imazaquin (imazaquin), imazethapyr (imazethapyr), imazosulfuron (imazosulfuron), indanofan (indanofan), indanofan, indanofando (Iodosulfuron), iodosulfuron-methyl-sodium, iofensulfuron, ioxynil, ioxynil-octanoate, ipfencarbazone, isoproturon (Isoproturon), isouron, isoxaben, isoxachlortole, isoxaflutole, isoxaflutole, lactofen, lenacil, linuron, male Maleic hydrazide, MCPA (2- (4-chloro-2-methylphenoxy) acetic acid), MCPB (4- (4-chloro-2-methylphenoxy) butanoic acid), mecoprop (mecoprop), mecoprop P ( mecoprop-P), mefenacet (mefenacet), meso-sulfuron (mesosulfuron), meso-sulfuron-methyl (mesosulfuron-methyl), mesotrione (mesotrione), metatam (metam), metamihop (metamifop), metamitron (metamitron), metazachlor (metazachlor), Metazosulfuron, methabenzthiazuron, methiozolin, methyzimolin, methyldymron, metobromuron, metolachlor, metosuron, metoxuron, metoxuron, metoxuron , Metsulfuron, metsulfuron methyl (mets ulfuron-methyl), molinate, monolinuron, naproanilide, napropamide, napropamide M, napropamide-M, naptalam, neburon, nicosulfuron, norflurazon (Norflurazon), oleic acid, orbencarb, orthosulfamuron, oryzalin, oryzalin, oxadiargyl, oxadiazon, oxasulfuron, oxaziclomefone , Oxyfluorfen, paraquat, paraquat-dichloride, pebulate, pelargonic acid, pendimethalin, penoxsulam, pen Tanocrol (pentanochlor), pentoxazone (pentoxazone), petoxamide (pethoxamid), phenisopham (phenisopham), phenmedipham (phenmedipham), picloram (picloram), pyrocorinafen (picolinafen), pinoxaden (pinoxaden), piperophos (piperophos) (Pretilachlor), primisulfuron (primisulfuron), primisulfuron-methyl (primisulfuron-methyl), prodiamine (prodiamine), profluazole (profluazol), propoxydim (profoxydim), prometon (prometon), promethrin (prometryn), Propachlor, propanil, propaquizafop, propazine, propham, propham, propisochlor, propoxycarbazone, propirisulfur (Propyrisulfuron), propyzamide, prosulfocarb, prosulfuron, pyraclonil, pyraclonil, pyraflufen-ethyl, pyrasulfotole, pyrazolynate, pyrazosulfuron ), Pyrazosulfuron-ethyl, pyrazoxyfen, pyribenzoxim, pyributicarb, pyributicarb, pyridafol, pyridate, pyridate, pyriftalid, pyriminobac, pyriminobac Methyl (pyriminobac-methyl), pyrimisulfan, pyrithiobac, pyroxasulfone, pyroxyslam, pyroxsulam, quinclorac, quinmerac (Quinmerac), quizalofop-ethyl, quizalofop-ethyl, quizalofop-tefuryl, quizalofop-P, quizalofop-P-ethyl, quizalofop-P-ethyl, quizalofop P-tefuril (quizalofop-P-tefuryl), rimsulfuron, saflufenacil, sethoxydim, sethoxydim, EPTC (S-ethyl N, N-dipropylcarbamothioate), siduron, siduron, simazine, simethrin ( simetryn), S-metolachlor (S-metolachlor), MSMA (sodium hydrogen methylarsonate), sulcotrione (sulcotrione), sulfentrazone (sulfentrazone), sulfometuron (sulfometuron), sulfometuron-methyl (sulfometuron-methyl), TCA Ethazyl (TCA-ethadyl), sulfosulfuron, swep, TCA (2,2,2-trichloroacet) ic acid), tebutam, tebuthiuron, tefuryltrione, tebotrione, tembotrione, tepraloxydim (tepraloxydim), terbacil, terbumeton, terbuthylazine, terbuthylazine terbutryn), tetflupyrolimet (tetflupyrolimet), taxomin A (thaxtomin A), tenylchlor (thenylchlor), thiazopyr (thiazopyr), thidiadimine (thidiazimin), thiencarbazone (thiencarbazone), thiencarbazone-methyl, thiencarbazone-methyl Luflon (thifensulfuron), thifensulfuron-methyl, thiafenacil, thioafazil, tiocarbazil, tolpyralate, topramezone, tralkoxydim, tril Phamon (triafamone), trialate (tri-allate), triasulfuron (triasulfuron), triaziflam (triaziflam), tribenuron (tribenuron), tribenuron-methyl (tribenuron-methyl), triclopyr (triclopyr), triclopyrbutyr ( triclopyr-butotyl, triclopyr-ethyl, triclopyr-triethylammonium, tridiphane, trietazine, trietazine, trifloxysulfuron, trifloxysulfuron sodium salt -sodium), trifludimoxazin, trifluralin, triflusulfuron, triflusulfuron-methyl, triflusulfuron-methyl, tritosulfuron, vernalate, compound X, 4- (4 -fluorophenyl) -6-[(2-hydroxy-6-oxo-1-cyclohexen-1-yl) carbonyl] -2-methyl-1,2,4-triazine-3,5 (2H, 4H) -dione, 2-chloro-N- (1-methyl-1H-tetrazol-5-yl) -3- (methylthio) -4- (trifluoromethyl) benzamide, 2-methyl-N- (5-methyl-1,3,4- oxadiazol-2-yl) -3- (methanesulfonyl) -4- (trifluoromethyl) benzamide, 4-amino-3-chloro-5-fluoro-6- (7-fluoro-1H-indol-6-yl) pyridine-2 -carboxylic acid,

Safeners Benoxacol, cloquintocet, cloquintocet-mexyl, cyometrinil, cyprosulfamide, dichlormid, dicyclonone, disulfoton (Disulfoton), daimuron, fenchlorazole, fenchlorazole-ethyl, fenclorim, fenclorim, flurazole, furilazole, furilazole, fluxofenim, hexim , Isoxadifen, isoxadifen-ethyl, mefenpyr, mefenpyr-ethyl, mefenpyr-diethyl, mefenate, mephenate, metcamamifen fen), oxabetrinil, 1,8-naphthalic anhydride, octane-1,8-diamine, AD-67 (4- (dichloroacetyl ) -1-oxa-4-azaspiro [4.5] decane), CL-304415 (4-carboxy-3,4-dihydro-2H-1-benzopyran-4-acetic acid), CSB (1-bromo-4- [ (chloromethyl) sulfonyl] benzene), DKA-24 (2,2-dichloro-N- [2-oxo-2- (2-propenylamino) ethyl] -N- (2-propenyl) acetamide), MG191 (2- ( dichloromethyl) -2-methyl-1,3-dioxolane), MG-838 (2-propenyl 1-oxa-4-azaspiro [4.5] decane-4-carbodithioate), PPG-1292 (2,2-dichloro-N- (1,3-dioxan-2-ylmethyl) -N- (2-propenyl) acetamide), R-28725 (3- (dichloroacetyl) -2,2-dimethyl-1,3-oxazolidine), R-29148 (3 -(dichloroacetyl) -2,2,5-trimethyl-1,3-oxazolidine), TI-35 (1- (dichloroacetyl) azepane),

Fungicide compound acibenzolar-S-methyl, aldimorph, amethoctrazine, aminopyrifen, amisulbrom, ammonium salts of phosphorous acid, Anilazine, azaconazole, azoxystrobin, basic copper sulfate, benalaxyl, benalaxyl M, benodanil, benomyl Benthiavalicarb, Benthiavalicarb, Benthivalicarb-isopropyl, Benzovindiflupyr, Binapacryl, Binapacryl, Biphenyl, Bitertanol, Bixafen, Blastafen Gin S (blasticidin-S), Rudeaux mixture (Bordeaux mixture), boscalid, bromothalonil, bromuconazole, bupirimate, bupirimate, calcium salts of phosphorous acid, captafol, Captan, carbendazim, carbendazim, carboxin, carpropamid, quinomethionate, chinome, chitin, chloroneb, chlorothalonil, chlorozolinate, coletochlorin B colletochlorin B), copper (II) acetate, copper (II) hydroxide, copper oxychloride, copper (II) sulfate (copper (II) sulfate), coumoxystrobin, cyazofamid, cyflufenamid Cymoxanil, cyproconazole, cyprodinil, cyprodinil, dichlobentiazox, dichlofluanid, dichlofluanid, diclosymet, diclomezine, dicloran, thocloran ), Difenoconazole, diflumetorim, dimethachlone, dimethirimol, dimethirimol, dimethomorph, dimoxystrobin, diniconazole, diniconazole M, diniconazole-M dinocap), dipotassium hydrogenphosphite, dipymetitrone, dithianon, bisethylenediamine copper (II) complex dodecylbenzenesulfonate (dode) cylbenzenesulphonic acid bisethylenediamine copper (II) salt), dodemorph, dodine, edifenphos, enoxastrobin, epoxiconazole, etaconazole, ethaboxam, etiriboxam (Ethirimol), etridiazole (etridiazole), famoxadone, fenamidone, phenaminestrobin (fenaminstrobin), fenarimol, fenarimol, fenbuconazole, fenfuram, fenhexamid , Fenoxanil, fenpiclonil, fenpicoxamide, fenpropidin, fenpropidin, fenpropimorph, fenpyrazamine, fenpyrazamine, trife acetate Niltin (fentin acetate), triphenyltin chloride (fentin chloride), triphenyltin hydroxide (fentin hydroxide), ferbam (ferbam), ferimzone (ferimzone), florylpicoxamide (florylpicoxamid), fluazinam (fluazinam), Fludioxonil, flufenoxystrobin, fluindapyr, flumorph, flumorph, fluopicolide, fluopimomide, fluopyram, fluoxaprolin, fluoxaproline Fluoxastrobin, fluquinconazole, fluquinconazole, flusilazole, flusulfamide, flutianil, flutianil, flutolanil, flutriafol, fluki Pyroxad (fluxapyroxad), folpet, fosetyl (fosetyl), fosetyl-aluminium, fiberidazole (fuberidazole), furaxyl (furalaxyl), furametpyr (furametpyr), guazatine, hexaconazole Hymexazole, imazalil, imimibenconazole, iminoctadine, iminoctadine acetate (iminoctadine triacetate), impilfluxam (inpyrfluxam), iodocarb, ipconazole (ipconazole) Trifluconazole (ipfentrifluconazole), ipflufenoquin (ipflufenoquin), iprobenfos (iprobenfos), iprodione (iprodione), iprovalicarb (iprovalicarb), isofetamide (isofetamid), isoflurcipram (iso flucypram), isoprothiolane, isopyrazam, isotianil, isotianil, kasugamycin, kresoxim-methyl, laminarin, mancozeb, mandestrobin, mandestrobin (Mandipropamid), maneb (maneb), mefentrifluconazole (mefentrifluconazole), mepanipyrim (mepanipyrim), mepronil (mepronil), meptyldinocap (meptyldinocap), metalaxyl (metalaxyl), metalaxyl M (metalaxyl-M), metaxonol metconazole), methasulfocarb, metiram, metominostrobin, metrafenone, methyltetraprole, machine oil (mineral oils), microbutanyl (myclobut) anil), naftifine, nuarimol, octhilinone, ofurace, orysastrobin (orysastrobin), oxadixyl (oxadixyl), oxathiapiproline (oxathiapiprolin), oxine copper (oxine-copper), oxolinic Acid (oxolinic acid), oxpoconazole (oxpoconazole), oxpoconazole fumarate (oxpoconazole fumarate), oxycarboxin (oxycarboxin), oxytetracycline (oxytetracycline), pefurazoate (pefurazoate), penconazole (penconazole), pencyclon (Pencycuron), penflufen, penthiopyrad, phenamacril, phosphorous acid, fusalide (phthalide), picarbutrazox (picarbutrazox), picoxystrobin (picoxystrobin), Peralin (piperalin), polyoxins (polyoxins), potassium bicarbonate (potassium hydrogencarbonate), potassium dihydrogen phosphite (potassium dihydrogenphosphite), probenazole (probenazole), prochloraz (prochloraz), procymidone (procymidone), propamidine (propamidine), propamidine (Propamocarb), propiconazole (propiconazole), propineb (propineb), proquinazide (proquinazid), prothiocarb (prothiocarb), prothioconazole (prothioconazole), pydiflumetofen (pydiflumetofen), pyraclostrobin (pyraclostrobin) Robin (pyrametostrobin), pyraoxystrobin (pyraoxystrobin), pyrapropoyne (pyrapropoyne), pyraziflumide (pyraziflumid), pyrazophos (pyrazophos), pyribencarb (pyribencarb), pyributicar b), pyridachlometyl, pyrifenox, pyrimetanil, pyrimorph, pyriophenone, pyriofenone, pyrisoxazole, pyroquilon, quinconazole, quinofazole ( quinofumelin), quinoxyfen, quintozene, quinoa saponins (Saponins of Chenopodium quinoa), sodium hydrogencarbonate (sodium hydrogencarbonate), sedaxane (sedaxane), silthiofam (silthiofam), simeconazole (simeconazole), Sodium salts (sodium salts of phosphorous acid), spiroxamine (spiroxamine), streptomycin (streptomycin), sulfur (sulfur), tebuconazole (tebuconazole), tebufloquin (tebufloquin), teclofthalam (teclofthalam), technase (Tecnazene), terbinafine (terbinafine), tetraconazole (tetraconazole), thiabendazole (thiabendazole), thifluzamide (thifluzamide), thiophanate (thiophanate), thiophanate-methyl (thiophanate-methyl), thiuram (thiram), thymol (thymol), thiazinyl ( tiadinil), tolclofos-methyl, tolfenpyrad, tolprocarb, tolylfluanid, tolylfluanid, triadimefon, triadimenol, triazoxide, triclopyricarb ), Tricyclazole (tricyclazole), tridemorph (tridemorph), trifloxystrobin (trifloxystrobin), triflumizole (triflumizole), triforine, triticonazole, triticonazole Damaishin (validamycin), Barifenareto (valifenalate), vinclozolin (vinclozolin), mustard powder (yellow mustard powder), zineb (zineb), zinc thiazole (zinc thiazole), ziram (ziram), zoxamide (zoxamide),

Insecticide compounds abamectin, acephate, acequinocyl, acequinocyl, acetamiprid, acetoprole, acrinathrin, acynonapyr, afidopyropena, afidopyropena (Alanycarb), aldicarb, alethrin, alpha-cypermethrin, alpha-endosulfan, aluminum phosphide, amitraz, azadirachtin, azamethichhos (Azamethiphos), azinphos-ethyl, azinphos-methyl, azocyclotin, bendiocarb, benfluthrin, benfluca Benfuracarb, bensultap, benzoximate, benzpyrimoxan, beta-cyfluthrin, beta-cypermethrin, bifenazate, bifenazate (Bifenthrin), bioallethrin (bioallethrin), bioresmethrin (bioresmethrin), bistrifluron (bistrifluron), borax (borax), boric acid (boric acid), brofuranilide (broflanilide), bromopropylate, buprofezin (buprofezin) ), Butocarboxime, butoxycarboxim, cadusafos, calcium cyanide, calcium phosphide, carbaryl, carbofuran, carbosulfan (Carbosulfan , Cartap hydrochloride, cartap, cartap, quinomethionat, chlorantraniliprole, chlordane, chlorethoxyne, chlorethoxyfos, chlorfenapyr, chlorfenvinphos , Chlorfluazuron, chlormephos, chlorpicrin, chloropicrin, chlorpyrifos, chlorpyrifos-methyl, chromafenozide, clofentezine, concanamycin A (concanacin A) ), Coumaphos, cryolite, cyanophos, cyanantraniliprole, cycloniliprole, cycloprothrin Cycloxaprid, cyenopyrafen, cyflumetofen, cyfluthrin, cyfluthrin, cyhalodiamide, cyhalothrin, cyhalothrin, cyhexatin, cypermethrin, cyphenothrin, cyphenothrin ), Dazomet, deltamethrin, demeton-S-methyl, diafenthiuron, diazinon, diazinon, dichlorvos, dichlororomezotiaz , Dicophor (dicofol), dicrotophos (dicrotophos), difluvidazin (diflovidazin), diflubenzuron (diflubenzuron), dimefluthrin (dimefluthrin), dimethoate (dimethoate), dimethylvinphos (dimethylvinphos), gympro Lidaz (Dimpropyridaz), dinotefuran, disodium octaborate, disulfoton, DNOC (2-methyl-4,6-dinitrophenol), doramectin, doramectin, emamectin benzoate benzoate), empentrin (empenthrin), endosulfan, EPN (O-ethyl O- (4-nitrophenyl) phenylphosphonothioate), epsilon-metofluthrin, epsilon-monfluorothrin, epsilon-momfluorothrin Rate (esfenvalerate), ethiofencarb (ethiofencarb), ethione (ethion), ethiprole (ethiprole), ethoprophos (ethoprophos), etofenprox (etofenprox), etoxazole (etoxazole), vanfur (famphur), fenamiphos (fenamiphos), fenazaquin (fenamiphos) fenazaquin), fenbu oxide Thassin (fenbutatin oxide), fenitrothion (fenitrothion), fenobcarb (fenobucarb), fenoxycarb (fenoxycarb), fenpropatrin (fenpropathrin), fenpyroximate (fenpyroximate), fenthion (fenthion), fenvalerate (fenvalerate), fipronil (fipronil), Flomethokin, flonicamid, fluacrypyrim, fluazaindolizine, fluazazuron, fluazuron, flubendiamide, flucycloxuron, flucycloxuron, flucythrinate, fluenthrin Sulfone (fluensulfone), flufenoxpron (flufenoprox), flufenoxuron (flufenoxuron), flufiprole (flufiprole), flumethrin (flumethrin), fluopyram (fluopyram), flupira Difuron (flupyradifurone), fluprimine (flupyrimin), fluraraner (fluralaner), fluvalinate (fluvalinate), fluxamethamide (fluxametamide), formethatenate (formetanate), fosthiazate (fosthiazate), furamethrin (furamethrin), furathiocarbin (gamma) (Gamma-cyhalothrin), GS-omega / kappa HXTX-Hv1a peptide (GS-omega / kappa HXTX-Hv1a peptide), halfenprox (halfenprox), halofenozide (halofenozide), heptafluthrin (heptafluthrin), heptenophos (heptenophos) , Hexaflumuron, hexythiazox, potassium salt of hop beta acid, hydramethylnon, hydroprene, imicyafos, imidacloprid , Imidaclothiz, imiprothrin, indoxacarb, indoxacarb, isocycloseram, isofenphos, isoprocarb, isoprocarb, isopropyl O- (methoxyaminothiophosphoryl) salicylate (isopropyl-O- (methoxyaminothiophosphoryl) salicylate), isoxathion, ivermectin, kadesthrin, kappa-tefluthrin, kappa-bifenthrin, kappa-bifenthrin, kinoprene, lambda-dahalothrin cyhalothrin, lenoremycin, lepimectin, lime sulfur mixture, lime sulfur, lotilaner, lufenuron, machine oil, malathion, mecarbam, mecarbam Phosphorus (meperfluthrin), metaflumizone (metaflumizone), metham (metam), methamidophos (methamidophos), methidathion (methidathion), methiocarb (methiocarb), mesomil (methomyl), methoprene (methoprene), methoxychlor, methoxyfenozide (methoxyfen) Methyl bromide, Metofluthrin, Metoflucarb, Methocarb, Methoxadiazone, Mevinphos, Milbemectin, Milbemycin oxime, Momfluorothrin, Monofluorothrin monocrotophos), moxidectin (moxidectin), nared (naled), neem oil (neem oil), nicotine (nicotine), nicotine-sulfate, nitenpyram (nitenpyram), novalron (novaluron), Novif Lumuron (noviflumuron), omethoate (omethoate), oxamyl (oxamyl), oxazosulfyl (oxazosulfyl), oxydimetone methyl (oxydemeton-methyl), parathion (parathion), parathion-methyl (parathion-methyl), permethrin (permethrin), Phenothrin, phenthoate, phorate, phosalone, phosmet, phosphamidon, phosphine, phoxim, pirimicarb, pirimiphos-methyl ), Potassium cyanide (potassium cyanide), praletrin (prallethrin), profenofos (profenofos), profluthrin (profluthrin), propargite (propargite), propetamphos (propetamphos), propoxur (propoxur), propylene arginate Propylene glycol alginate, prothiofos, pyflubumide, pymetrozine, pyraclofos, pyrethrins, pyridaben, pyridalyl, pyridafenquinone, pyridafenquinone ), Pyrimidifen, pyriminostrobin, pyriprole, pyriproxyfen, quinalphos, resmethrin, rotenone, ryanodine, sarolaner ), Selamectin, sigma-cypermethrin, silafluofen, sodium borate, sodium cyanide, sodium metaborate ium metaborate, spinetoram, spinosad, spirodiclofen, spiromesifen, spiromesifen, spiropidion, spirotetramat, sulfluramid, sulfotep Sulfoxaflor, sulfuryl fluoride, tartar emetic, tau-fluvalinate, tebufenozide, tebufenpyrad, tebupirimfos, tebubenzuron, teflubenzuron Tefluthrin, temephos, terbufos, tetrachlorantraniliprole, tetrachlorvinphos, tetradifon, tetramethrin , Tetramethylfluthrin, tetraniliprole, theta-cypermethrin, thetacloprid, thiacloprid, thiamethoxam, thiocyclam, thiocyclam, thiodicarb, thiophanox ( thiofanox), thiometon, thiosultap-disodium, thiosultap-monosodium, thiosultap-monosodium, thioxazafen (tioxazafen), tolfenpyrad, tralomethrin, transfluthrin, Triazamate, triazophos, trichlorfon, triflumezopyrim, triflumuron, triflumuron, trimethacarb, ticlopyrazov Roll (tyclopyrazoflor), vamidothion (vamidothion), XMC (3,5-dimethylphenyl N-methylcarbamate), xylylcarb (xylylcarb), zeta-cypermethrin (zeta-cypermethrin), zinc phosphide (zinc phosphide), compound Y,

Plant growth regulator compound 1-methylcyclopropene (1-methylcyclopropene), 1,3-diphenylurea (1,3-diphenylurea), 2,3,5-triiodobenzoic acid (2,3,5-triiodobenzoic acid), IAA ((1H-indol-3-yl) acetic acid), IBA (4- (1H-indol-3-yl) butyric acid), MCPA (2- (4-chloro-2-methylphenoxy) acetic acid), MCPB (4- (4-chloro-2-methylphenoxy) butyric acid), 4-CPA (4-chlorophenoxyacetic acid), 5-aminolevulinic acid hydrochloride, 6-benzylaminopurine , Abscisic acid, AVG (aminoethoxyvinylglycine), ansimidol (ancymidol), buturealine (butralin), calcium carbonate (calcium carbonate), calcium chloride (calcium chloride), calcium formate (calcium formate), calcium peroxide ( calcium peroxide), calcium polysulfide, calcium sulfate Calcium sulfate, chlormequat-chloride, chlorpropham, chlorpropham, choline chloride, cloprop, cyanamide, cyaniamide, cyclanilide, daminozide Decan-1-ol, dichlorprop, dikegulac, dimethipin, diquat, ethephon, ethychlozate, flumetralin, Flurprimidol, forchlorfenuron, formononetin, gibberellin A, gibberellin A3, hymexazol, inabenfide, isoprothione Kinetin ), Lipochitooligosaccharides (eg, lipochitooligosaccharide SP104), maleic hydrazide, mefluidide, mefluidide, mepiquat-chloride, oxidized glutathione, pacrobutrazol , Pendimethalin, prohexandione-calcium, prohydrojasmon, pyraflufen-ethyl, sintofen, sodium 1-naphthaleneacetate ), Sodium cyanate, streptomycin, thidiazuron, triapenthenol, tribufos, trinexapac-ethyl, uniconazole P (uniconaz) ole-P), 2- (naphthalene-1-yl) acetamide (2- (naphthalene-1-yl) acetamide), [4-oxo-4- (2-phenylethyl) amino] butyric acid, 5- (trifluoro Methyl) benzo [b] thiophen-2-carboxylate, 3-[(6-chloro-4-phenylquinazolin-2-yl) amino] propan-1-ol.

Compound X in compound group A is a compound represented by the following formula (1) and described in US Pat. No. 6,537,948, and can be produced by a known method.

Compound Y in compound group A is a compound represented by the following formula (2) and described in WO 2017/065228, and can be produced by a known method.

  Some of the compound groups A take the form of an agriculturally acceptable salt with an inorganic base or an organic base or the like, but the present invention also includes the use of an agricultural chemical compound in the form of the salt. You. Such salts include, for example, inorganic bases (eg, hydroxides, carbonates, bicarbonates, acetates, hydrides, etc. of alkali metals (lithium, sodium, potassium, etc.), and alkaline earth metals (magnesium, calcium, etc.). Hydroxides, hydrides and the like of barium and the like, ammonia), organic bases (eg, dimethylamine, triethylamine, piperazine, pyrrolidine, piperidine, 2-phenylethylamine, benzylamine, ethanolamine, diethanolamine, pyridine, collidine and the like), Salts formed by mixing with metal alkoxides (eg, sodium methoxide, potassium tert-butoxide, magnesium methoxide, and the like) are included.

  Among the compound groups A, there are known crystal polymorphs having different crystal structures. In the present invention, all of these crystal polymorphs and a mixture comprising any two or more of them are used. Included.

  The preparation of the composition of the present invention contains a major drug substance and a minor drug substance and an inert carrier. The preparation of the composition of the present invention is usually prepared by mixing a main drug substance and a trace drug substance with an inert carrier such as a solid carrier, a liquid carrier, and a gaseous carrier. Add emulsions, oils, powders, granules, wettable powders, flowables, microcapsules, aerosols, smokers, poison baits, resin preparations, shampoos, pastes, foams, carbon dioxide It is formulated into gas preparations, tablets and the like. These preparations may be processed into mosquito coils, electric mosquito repellent mats, liquid mosquito repellent preparations, fumigation agents, fumigants, sheet preparations, spot-on preparations, and oral treatments.

  Examples of the solid carrier used in the formulation include clays (kaolin clay, diatomaceous earth, bentonite, acid clay, etc.), synthetic hydrous silicon oxide, talc, ceramics, and other inorganic minerals (sericite, quartz, sulfur, activated carbon) , Calcium carbonate, hydrated silica, etc.), and synthetic resins (polyester resins such as polypropylene, polyacrylonitrile, polymethyl methacrylate, and polyethylene terephthalate), nylon resins such as nylon-6, nylon-11 and nylon-66, polyamide resins, Polyvinyl chloride, polyvinylidene chloride, vinyl chloride-propylene copolymer, etc.).

  Examples of the liquid carrier include water, alcohols (methanol, ethanol, isopropyl alcohol, butanol, hexanol, benzyl alcohol, ethylene glycol, propylene glycol, phenoxyethanol, etc.), ketones (acetone, methyl ethyl ketone, cyclohexanone, etc.), aromatic hydrocarbons (E.g., toluene, xylene, ethylbenzene, dodecylbenzene, phenylxylylethane, methylnaphthalene), aliphatic hydrocarbons (hexane, cyclohexane, kerosene, light oil, etc.), esters (ethyl acetate, butyl acetate, isopropyl myristate) Ethyl oleate, diisopropyl adipate, diisobutyl adipate, propylene glycol monomethyl ether acetate, etc.), nitriles (acetonitrile, isobutyro) Ethers (diisopropyl ether, 1,4-dioxane, ethylene glycol dimethyl ether, diethylene glycol dimethyl ether, diethylene glycol monomethyl ether, propylene glycol monomethyl ether, dipropylene glycol monomethyl ether, 3-methoxy-3-methyl-1-butanol, etc.) ), Acid amides (N, N-dimethylformamide, N, N-dimethylacetamide, etc.), halogenated hydrocarbons (dichloromethane, trichloroethane, carbon tetrachloride, etc.), sulfoxides (dimethylsulfoxide, etc.), propylene carbonate and vegetable oil (Soy oil, cottonseed oil, etc.).

  Examples of the gaseous carrier include fluorocarbon, butane gas, LPG (liquefied petroleum gas), dimethyl ether, and carbon dioxide gas.

  Examples of the surfactant include nonionic surfactants such as polyoxyethylene alkyl ether, polyoxyethylene alkyl aryl ether, and polyethylene glycol fatty acid ester, and anions such as alkyl sulfonate, alkyl benzene sulfonate and alkyl sulfate. Surfactants.

  Other adjuvants for preparations include fixing agents, dispersants, coloring agents and stabilizers, specifically, casein, gelatin, sugars (starch, gum arabic, cellulose derivatives, alginic acid, etc.), lignin derivatives, bentonite, Synthetic water-soluble polymer (polyvinyl alcohol, polyvinylpyrrolidone, polyacrylic acid, etc.), PAP (isopropyl acid phosphate), BHT (2,6-di-tert-butyl-4-methylphenol), BHA (2-tert- A mixture of butyl-4-methoxyphenol and 3-tert-butyl-4-methoxyphenol).

  Examples of the base material for the resin preparation include vinyl chloride polymers and polyurethanes. These base materials may be phthalic acid esters (dimethyl phthalate, dioctyl phthalate, etc.), adipic acid esters if necessary. , A plasticizer such as stearic acid may be added. The resin formulation is obtained by kneading the compound in the base material using a usual kneading apparatus, and then molding by injection molding, extrusion molding, press molding, and the like. It can be processed into resin preparations such as plate, film, tape, net, and string. These resin preparations are processed, for example, as animal collars, animal ear tags, sheet preparations, drawstrings, and horticultural supports.

  Examples of the bait bait include, for example, cereal flour, vegetable oil, sugar, crystalline cellulose, etc., and, if necessary, an antioxidant such as dibutylhydroxytoluene and nordihydroguaiaretic acid, and a preservative such as dehydroacetic acid. In addition, an anti-feeding agent for children and pets, such as pepper powder, a cheese flavor, an onion flavor, pest-inducing flavors such as peanut oil, and the like are added.

  The total content of the agrochemical compound in the composition of the present invention is usually in the range of 0.01 to 99% by weight, preferably 1 to 80% by weight, more preferably 2 to 50% by weight, and still more preferably 10 to 30% by weight. It is. Specifically, 3 wt%, 6 wt%, 8 wt%, 12 wt%, 15 wt%, 20 wt%, 25 wt%, 40 wt%, 60 wt%, 70 wt%, 90 wt%, etc. No.

In the composition of the present invention, the weight ratio between the main drug substance and the minor drug substance is 1/10 ＾ 3 or less in the ratio of the trace drug substance / the main drug substance. Specifically, 1/10 微量 3, 1/10 ＾ 4, 1/10 ＾ 5, 1/10 ＾ 6, 1/10 ＾ 7, 1/10 ＾ 8, 1/10 / 10 9, 1/10 ＾ 10, 1/10 ＾ 11, 1/10 ＾ 12, 1/10 ＾ 13, 1/10 ＾ 14, 1/10 ＾ 15 and the like. Here, the caret symbol “＾” is an operator representing a power, for example, “10 ＾ 5” means “10 ⁵ ” (that is, 10 to the fifth power) (hereinafter the same).

  From this section, when the main drug substance or the trace drug substance is a salt, the weight ratio usually means the ratio by the salt, but the ratio of the acid equivalent is also disclosed.

  Preferred pesticidal compounds as the main drug substance include flumioxazine, compound X, imazosulfuron, propylisulfuron, sulfosulfuron, bromobutide, butamiphos, flumicrolacpentyl, lactofen, clethodim, 2,4-D choline salt, dicambabipro Amine, dicambadiglycolamine salt, dicambatetrabutylamine salt, glyphosate potassium salt, glyphosate monoethanolamine salt, glufosinate ammonium salt, clothianidin, oxazosulfyl, compound Y, nitenpyram, cartap, fenitrothion, esfenvalerate, fenpropa Trin, pyriproxyfen, ethoxazole, pyridalyl, impilfluxam, methyltetraprole, pyridaclomethyl, procymidone, tolclofosmethyl, oxo Clinics acid, furametpyr, diclocymet, ferimzone, validamycin, isotianil, diniconazole M, include the man d'Est robin. Preferred pesticide compounds as the trace drug substance are flumioxazine, compound X, imazosulfuron, propylisulfuron, sulfosulfuron, bromobutide, butamiphos, flumilaclacpentyl, lactofen, clethodim, clothianidin, oxazosulfyl, compound Y, nitenpyram, Cartap, fenitrothion, esfenvalerate, fenpropatrin, pyriproxyfen, ethoxazole, pyridalyl, impilfluxam, methyltetraprole, pyridaclomethyl, procymidone, tolclofosmethyl, oxolinic acid, flametopyr, diclosimet, ferimzone, validamycin, isotianil , Diniconazole M, and mandestrobin.

  The composition of the present invention, for a wide range of pests, exerts a more synergistic control effect than expected from the control effect when the main drug substance or a trace drug substance is used alone, and ordinary tillage cultivation, A wide range of pests can be effectively controlled in agricultural and vegetable fields, orchards (including orchards) and non-agricultural lands where no-tillage cultivation is performed. Furthermore, if no phytotoxicity that causes a problem to useful plants is caused, and if phytotoxicity is caused without using a trace substance, it is reduced or eliminated in the composition of the present invention. Moreover, in the composition of the present invention, superior physicochemical properties are obtained as compared with the composition when used without a trace substance.

  The composition of the present invention may be used in combination with other pesticidal compounds, in addition to the main drug substance and the trace drug substance. In that case, the weight ratio may be about the same as that of the main drug substance (1/100 to 100 times), but the weight ratio range of the trace drug substance (independent of the trace drug substance with respect to the main drug substance, usually 1: 1) / 10 ＾ 15 to 1/10 ＾ 3).

  The pest control method of the present invention (hereinafter referred to as the method of the present invention) is a method in which pests are generated or generated in a crop field, a vegetable field, an orchard or a non-agricultural land, etc. And a step of applying it to a place to be applied. In crop fields and vegetable fields, apply to the crop seeds or, if not to the seeds, before and at the same time and / or after sowing of the crop seeds, It may be applied to the field.

  The method of the present invention has a step of simultaneously applying or sequentially applying a main drug substance and a trace drug substance to a place (including a seed) where a pest is occurring or occurs. When applied sequentially, the order in which the main drug substance and the trace drug substance are applied is not particularly limited. The simultaneous application includes the case where the composition of the present invention is applied.

  In the method of the present invention, the weight ratio of the main drug substance and the trace drug substance is 1/10 ＾ 3 or less in the ratio of the trace drug substance / the main drug substance. Specifically, 1/10 微量 3, 1/10 ＾ 4, 1/10 ＾ 5, 1/10 ＾ 6, 1/10 ＾ 7, 1/10 ＾ 8, 1/10 / 10 9, 1/10 ＾ 10, 1/10 ＾ 11, 1/10 ＾ 12, 1/10 ＾ 13, 1/10 ＾ 14, 1/10 ＾ 15 and the like.

  When the method of the present invention is not carried out on seeds and is used in cultivation of agricultural crops, one or more compounds selected from the group consisting of insecticide compounds, nematicide compounds and fungicide compounds are treated. Before, simultaneously with, and / or after sowing of the crop seed, the main drug substance and the trace drug substance may be applied to a field where the crop seed is sown or a field where the seed is to be sown.

Examples of plants to which the composition of the present invention can be used include the following.
Agricultural crops: Maize (horse tooth, hard grain, soft grain, explosive, glutinous, sweet), rice (long grain, short grain, medium grain, japonica, tropical japonica, indica, jawanica, rice) , Upland rice, floating rice, direct sowing, transplantation, glutinous rice), wheat (bread wheat (hard, soft, medium, red, white), macaroni, spelled, club wheat, autumn and spring sowing, respectively) , Barley (Nijo barley (= beer wheat), Rokujo barley, Hadakamu, and wheat, each fall-sown type, spring-sown type), rye (fall-sown type, spring-sown type), triticale (fall-sown type, spring-sown type) , Oat (autumn sowing type, spring sowing type), sorghum, cotton (upland type, pima type), soybean (infinite growth type, finite growth type, semi-finite growth type), peanut (peanut), Saito ( Bean beans, bean beans, adzuki beans, cowpea, mung bean, uradame beans, safflower beans, takaeuzuki, moss bean, tepali bean, fava beans, peas, chickpeas, lentils, lupine, bean beans, alfalfa, buckwheat, sugar beet, rapeseed, canola, spring seeding Type), sunflower, sugarcane, tobacco, etc.
Vegetables: Solanaceous vegetables (eggplant, tomato, pepper, capsicum, bell pepper, potato, etc.), Cucurbite vegetables (cucumber, pumpkin, zucchini, watermelon, melon, squash, etc.), Brassicaceae vegetables (radish, turnip, horseradish, Kohlrabi, Chinese cabbage, cabbage, mustard, broccoli, cauliflower, etc., Asteraceae vegetables (burdock, shungiku, artichoke, lettuce, etc.), lily vegetables (leek, onion, garlic, asparagus, etc.), and Umbelliferous vegetables (carrot, parsley) , Celery, American spinach, etc.), red crab vegetables (spinach, chard etc.), lamiaceae vegetables (perilla, mint, basil, lavender, etc.), strawberry, sweet potato, yam, taro etc.,
Fruit trees; Nuts (apples, pears, Japanese pears, karin, quince, etc.), drupes (peaches, plums, nectarines, plums, sweet cherry, apricots, prunes, etc.), citrus fruits (unshiu mandarin, orange, lemon, lime, grapefruit) ), Nuts (chestnuts, walnuts, hazelnuts, almonds, pistachios, cashew nuts, macadamia nuts, etc.), berries (blueberries, cranberries, blackberries, raspberries, etc.), grapes, oysters, olives, loquats, bananas, coffee, Date palm, coconut palm, etc.
Others: tea, mulberry, flowering trees, street trees (ash, birch, dogwood, eucalyptus, ginkgo, lilac, maple, oak, poplar, hanazou, fu, sycamore, zelkova, kurobe, mominoki, tsuga, pine, pine, spruce, yew ), Flowers, houseplants, grasshoppers, pastures.

  Examples of the non-cultivated land in the present invention include an athletic ground, a vacant lot, a track end, a park, a parking lot, a road end, a riverbed, under a transmission line, a residential land, a factory site, and the like.

  The above-mentioned plant may be a plant that can be produced by natural crossing, a plant that can be generated by mutation, an F1 hybrid plant, or a transgenic plant (also referred to as a transgenic plant). These plants are generally resistant to herbicides, accumulate toxic substances to pests (also called pest resistance), suppress susceptibility to diseases (also called disease resistance), increase yield potential, increase biological and abiotic potential. It has properties such as improvement in resistance to stress factors and quality modification of products (for example, increase / decrease in the content of specific components, change in composition, improvement in preservability or processability).

  An F1 hybrid plant is a first-generation hybrid obtained by crossing varieties of two different strains, and is generally a plant having the characteristics of heterosis with superior traits than either of the parents. Transgenic plants are introduced by introducing foreign genes from other organisms such as microorganisms, so as to impart characteristics that cannot be easily obtained by cross breeding, mutagenesis or natural recombination in the natural environment. Plant.

  Techniques for producing the above-mentioned plants include, for example, conventional breeding techniques; genetic recombination techniques; genome breeding techniques; new breeding techniques; and genome editing techniques. The conventional breeding technique is a technique for obtaining a plant having desirable properties by mutation or crossing. Genetic recombination technology is a technology that gives a new property to an organism by extracting a target gene (DNA) from an organism (for example, a microorganism) and introducing it into the genome of another target organism. Antisense or RNA interference technology that confers new or improved properties by silencing other genes present. Genomic breeding technology is a technology for improving breeding efficiency using genomic information, and includes DNA marker (also called genomic marker or gene marker) breeding technology and genomic selection. For example, DNA marker breeding is a method in which a progeny having a desired useful trait gene is selected from a large number of crossed progeny using a DNA marker that is a DNA sequence that serves as a marker of the location of a specific useful trait gene on the genome. is there. By analyzing the progeny of the cross using DNA markers when they are young plants, they have the characteristic that the time required for breeding can be shortened effectively.

  In addition, genomic selection is a method of creating prediction formulas from phenotypes and genomic information obtained in advance and predicting characteristics without evaluating phenotypes from prediction formulas and genomic information, contributing to efficiency of breeding It is a technology that can be done. The term “new breeding techniques” is a general term for breeding (breeding) techniques that combine molecular biological techniques. For example, cisgenesis / intragenesis, oligonucleotide-directed mutagenesis, RNA-dependent DNA methylation, genome editing, grafting to GM rootstocks or scions, reverse breeding, agroinfiltration, seed production technology (Seed Production) Technology, SPT). The genome editing technique is a technique for converting genetic information in a sequence-specific manner, and is capable of deleting a base sequence, replacing an amino acid sequence, introducing a foreign gene, and the like. Examples of such tools include zinc finger nucleases (Zinc-Finger Nucleases, ZFN, and ZFNs) that are capable of sequence-specific DNA cleavage, TALEN, Chrisper Casnin (CRISPR / Cas9), and Crisper CPF1 (CRISPER). / Cpf1) and meganuclease (Meganuclease). There are also sequence-specific genomic modification techniques such as CAS9 nickase and Target-AID created by modifying the aforementioned tools.

  Examples of the above-mentioned plants include genetically modified crops (http://www.isaaa.org/) in an electronic information site (http://www.isaaa.org/) of the International Agri-biotechnology Corporation (INTERNATINAL SERVICE for the ACQUISITION of AGRI-BIOTECH APPLICATIONS, ISAAA). Plants listed in the registration database (GM APPROVAL DATABASE) can be mentioned. More specifically, for example, herbicide-tolerant plants, pest-tolerant plants, disease-tolerant plants, and quality-modified products (for example, increase or decrease in component content, change in composition, improvement in preservability or processability) plants , Fertility trait modified plants, abiotic stress-tolerant plants, or trait modified plants related to growth and yield.

  Examples of plants to which herbicide tolerance has been imparted are given below.

  Mechanisms of herbicide resistance include, for example, reducing the affinity of the herbicide with its target; rapid metabolism (degradation, modification, etc.) of the herbicide by expression of enzymes that inactivate the herbicide; Inhibition of uptake into plants; and inhibition of translocation of herbicides in plants.

  Plants to which herbicide tolerance has been imparted by genetic recombination techniques include, for example, protoporphyrinogen oxidase (hereinafter abbreviated as PPO) herbicides such as flumioxazin; Dioxygenase (hereinafter abbreviated as HPPD) inhibitors; imidazolinone herbicides such as imazethapyr; acetolactate synthase (hereinafter abbreviated as ALS) inhibitors such as sulfonylurea herbicides such as thifensulfuron-methyl; glyphosate and the like 5-enolpyruvylshikimate-3-phosphate synthase (hereinafter abbreviated as EPSPS) inhibitor; glutamine synthase inhibitors such as glufosinate; auxin-type herbicides such as 2,4-D and dicamba; bromoxynil and the like There are plants to which resistance to oxynil herbicides has been imparted. Preferred herbicide-tolerant transgenic plants include wheat, barley, rye, oats and other wheat, canola, sorghum, soybean, corn, cotton, rice, rape, sugar beet, sugar cane, grapes, lentils, sunflower, alfalfa, fruits Vegetables, such as drupe, coffee, tea, strawberry, buckwheat, tomato, potato, cucumber, lettuce, more preferably wheat, barley, rye, oats, etc., soybean, corn, rice, grapes, tomato, Potatoes and fruits.

  The following shows specific herbicide-tolerant plants.

  Glyphosate herbicide-resistant plant: a glyphosate-resistant EPSPS gene (CP4 epsps) derived from Agrobacterium tumefaciens strain CP4 and a glyphosate N-acetyltransferase gene derived from Bacillus licheniformis. N-acetyltransferase gene (gat4601 or gat4621), glyphosate oxidase gene (goxv247) derived from Ochrobacterum anthropi strain LBAA (goxv247), or EPSPS gene having a glyphosate resistance mutation derived from corn (Zea mays) ( mepsps or 2mepsps). The main plants are, for example, alfalfa (Medicago sativa), Argentine canola (Brassica napus), cotton (Gossypium hirsutum L.), creeping bentgrass (Agrostis stolonifera), corn (Zea mays L.) polished canola (Brassica rapa), Potato (Solanum tubeHDDrosum L.), soybean (Glycine max L.), sugar beet (Beta vulgaris) and wheat (Triticum aestivum). Several glyphosate-tolerant plants are commercially available. For example, a transgenic plant into which CP4 epsps has been introduced is a trade name including “Roundup Ready (registered trademark)”, and a transgenic plant into which gat4601 or gat4621 has been introduced is “Optimum GAT (registered trademark)”, “Optimum (registered trademark)”. Genetically modified plants into which mepsps or 2mepsps have been introduced under a trade name such as ") Gly canola" are sold under the trade name "GlyTol (trademark)". As more specific glyphosate-tolerant plants, for example, corn is `` Roundup Ready (trademark) Maize '', `` Roundup Ready (trademark) 2 Maize '', `` Agrisure (trademark) GT '', `` Agrisure (trademark) GT / CB / LL "," Agrisure (TM) GT / RW "," Agrisure (TM) 3000GT "," YieldGard (TM) VT (TM) Rootworm (TM) RR2 "and" YieldGard (TM) VT Triple "; Ready (TM) Soybean "and" Optimum GAT (TM) "; Cotton is" Roundup Ready (TM) Cotton "," Roundup Ready (TM) Flex Cotton "and" GlyTol (TM) "; Canola is" Roundup Ready (TM) " Canola "and" Optimum® Gly canola "; Alfalfa is" Roundup Ready (TM) Alfalfa "; Rice is" Roundup Ready Rice "; Sugarcane is" Roundup Ready (TM) sugarbeet "and" InVigor (TM) sugarbeet " Wheat sold under the trade name “Roundup Ready ™ wheat” (Triticum aestivum) Have been.

  Glyphosinate herbicide-tolerant plants: Streptomyces hygroscopicus-derived phosphinothricin N-acetyltransferase (Phosphinothricin N-acetyltransferase, hereinafter abbreviated as PAT) gene (bar), Streptomyces bilideclo At least one of the PAT gene (pat) derived from Mogenes (Streptomyes viridochromogenes) or the synthesized PAT gene (pat syn) derived from Streptomyes viridochromogenes strain Tu494 Obtained by introduction. As main plants, for example, Argentine canola (Brassica napus), chicory (Cichorium intybus) cotton (Gossypium hirsutum L.), corn (Zea mays L.) polished canola (Brassica rapa), rice (Oryza sativa L.), soybean (Glycine max L.) and sugar beet (Beta vulgaris). Some glufosinate-tolerant plants are commercially available. For example, transgenic plants into which bar or pat has been introduced are sold under the trade names “LibertyLink ™”, “InVigor ™”, or “WideStrike ™”. More specific glyphosinate-tolerant plants include, for example, corn “Roundup Ready ™ 2”, “Liberty Link ™”, “Herculex ™ I”, “Herculex RW”, “Herculex XTRA ™” , "Agrisure (trademark) GT / CB / LL", "Agrisure (trademark) CB / LL / RW" and "Bt10"; cotton is "FiberMax (trademark) Liberty Link (trademark)"; rice is "Liberty Link (trademark) ) Rice; canola under the trade name “inVigor ™ Canola”; soybeans under the trade name “Liberty Link ™ Soybean”; sugar cane under the trade name “Liberty Link ™ sugarbeet”.

Oxynil herbicide (for example, bromoxynil) resistant plants: Obtained by introducing a nitrilase gene (bxn) from Klebsiella pneumoniae subsp. Ozaenae. Main plants include, for example, Argentine canola (Brassica napus), cotton (Gossypium hirsutum L.) and tobacco (Nicotiana tabacum L.). Several oxynil herbicide-tolerant plants are commercially available. For example, it is sold under a trade name including “Navigator (trademark)” or “BXN (trademark)”. As more specific oxynyl herbicide-tolerant plants, for example, cotton is sold under the trade name of "BXN (trademark) Cotton"; Argentina canola is sold under the trade name of "Navigator (trademark) Cotton".
ALS herbicide-tolerant plant: Carnation (Dianthus caryophyllus) into which an ALS herbicide-tolerant ALS gene (surB) derived from tobacco (Nicotiana tabacum) is introduced as a selection marker is, for example, "Moondust (trademark)" or "Moonshadow (trademark)" , Moonshade (TM), Moonlite (TM), Moonaqua (TM), Moonvista (TM), Moonique (TM), Moonpearl (TM), Moonberry (TM) Or sold under the trade name "Moonvelvet (TM)". A flax (Linum usitatissumum L.) into which an ALS herbicide-resistant ALS gene (als) derived from Arabidopsis thaliana has been introduced is sold, for example, under the trade name of “CDC Triffid Flax”. Maize (Zea mays L.), which is resistant to sulfonylurea and imidazolinone herbicides into which a maize-derived ALS herbicide-resistant ALS gene (zm-hra) has been introduced, is, for example, a trademark of "Optimum GAT (trademark)". Sold by name. A soybean having resistance to an imidazolinone herbicide into which an ALS herbicide-resistant ALS gene (csr1-2) derived from Arabidopsis thaliana is introduced is sold, for example, under the trade name of “Cultivance”. Soybeans into which the ALS herbicide-resistant ALS gene (gm-hra) derived from soybean (Glycine max) has been introduced are, for example, trademarks of “Treus ™”, “Plenish ™” and “Optimum GAT ™”. Sold by name. There is also a cotton into which the ALS herbicide-resistant ALS gene (S4-HrA) derived from tobacco (Nicotiana tabacum cv. Xanthi) has been introduced.

  HPPD herbicide-tolerant plant: obtained by introducing the HPPD gene (avhppd-03) derived from oat (Avena sativa). For example, at the same time as the above gene, a soybean into which a PAT gene (pat) derived from Streptomyces viridochromogenes (Streptomyes viridochromogenes) has been introduced, a soybean resistant to mesotrione and glufosinate has a "Herbicide-tolerant Soybean line" Sold under the trade name.

  2,4-D-tolerant plant or ACCase herbicide-tolerant plant: Sphingobium herbicidovorans-derived allyloxyalkanoate dioxygenase (aryloxyalkanoate dioxygenase) gene (aad-1) introduced 2 Corn resistant to, 4-D or ACCase herbicides is sold, for example, under the trade name "Enlist (TM) Maize". Soybeans and cotton that are resistant to 2,4-D or ACCase herbicides into which an allyloxyalkanoate dioxygenase gene (aad-12) derived from Delftia acidovorans has been known, for example, It is sold under the trade name "Enlist (TM) Soybean".

  Dicamba herbicide-resistant plant: obtained by introducing a dicamba monooxygenase gene (dmo) derived from Stenotrophomonas maltophilia strain DI-6. Soybeans and cottons into which the above genes have been introduced are known. A soybean (Glycine max L.) into which a glyphosate-resistant EPSPS gene (CP4 epsps) derived from Agrobacterium tumefaciens strain CP4 was introduced at the same time as the above-mentioned gene, for example, “Genuity® Roundup” Ready ™ 2 Xtend ™.

  Further plants with altered herbicide resistance are widely known, e.g., alfalfa, apple, barley, eucalyptus, flax, grape, lentil, rape, rape, pea, potato, rice, sugar beet having tolerance to glyphosate , Sunflower, tobacco, tomato bugs and wheat (see, for example, US5188642, US4940835, US5633435, US5804425, US5627061); beans, cotton, soybean, pea, potato, sunflower, tomato, tobacco, resistant to dicamba Corn, sorghum and sugarcane (see, for example, WO2008 / 051633, US7105724 and US5670454); soybean, sugar beet, potato, tomato and tobacco (see, for example, US6376754, US5646024, US5561236) resistant to glufosinate; Cotton, peppers, resistant to -D Apple, tomato, sunflower, tobacco, potato, corn, cucumber, wheat, soybean, sorghum and cereals (see, eg, US6153401, US6100446, WO2005 / 107437, US5608147 and US5670454); ALS-inhibiting herbicides (eg, sulfonylurea herbicides) , Corn, barley, millet, barley, cotton, mustard, lettuce, lentil, melon, millet, oats, nata, potato, rice, rye, sorghum, Soybean, sugar beet, sunflower, tobacco, tomato and wheat (see, for example, US5013659, WO2006 / 060634, US4761373, US5304732, US6211438, US6211439 and US6222100), especially rice having resistance to imidazolinone herbicides are known, A specific mutation (acetohydroxyacid synthase gene) For example, rice having S653N, S654K, A122T, S653 (At) N, S654 (At) K, A122 (At) T (for example, see US2003 / 0217381, WO2005 / 020673); HPPD-inhibiting herbicides (for example, isoxa) Isoxazole herbicides such as flutol; triketone herbicides such as sulcotrione and mesotrione; and pyrazole herbicides such as pyrazolinate) or barley, sugarcane, and rice which are resistant to diketonitrile, a degradation product of isoxaflutole. Corn, tobacco, soybean, cotton, rapeseed, sugar beet, wheat and potato (see, for example, WO2004 / 055191, WO1996 / 38567, WO1997 / 049816 and US6791014); and wheat, soybean resistant to PPO-inhibiting herbicides. , Cotton, sugar beet, rapeseed, rice, corn, sorghum, sugarcane and sugar beet (for example, US2002 / 0073443, US2008 / 0052798, Pest Management Science, 6 1, 2005, 277-285).

  As a plant to which a herbicide tolerance has been imparted by a conventional breeding technique or a genomic breeding technique, for example, a rice “Clearfield (registered trademark) Rice” which is resistant to imidazolinone-based ALS-inhibiting herbicides such as imazethapyr and imazamox. , Wheat "Clearfield (R) Wheat", sunflower "Clearfield (R) Sunflower", lentil "Clearfield (R) lentils" and canola "Clearfield (R) canola" (product of BASF); Soybean “STS soybean” resistant to sulfonylurea-based ALS-inhibiting herbicides such as methyl; corn “SR corn” resistant to acetyl-CoA carboxylase inhibitors such as trione oxime-based herbicides and aryloxyphenoxypropionic acid-based herbicides (Also known as “Poast Protected® corn”); Tribenuron et al. Sunflower “ExpressSun®” resistant to sulfonylurea herbicides; Rice “Provisia ™ Rice” resistant to acetyl-CoA carboxylase inhibitors such as quizalofop; and canola resistant to photosystem II inhibitors Triazine Tolerant Canola "; sorghum" Igrowth (TM) "which is resistant to imidazolinone herbicides.

  As a plant to which herbicide resistance has been imparted by genome editing technology, a canola “SU Canola (registered trademark)” having sulfonylurea-based herbicide resistance using rapid variety development technology (Rapid Trait Development System, RTDS (registered trademark)) Is mentioned. RTDS (registered trademark) corresponds to oligonucleotide-directed mutagenesis of genome editing technology. Gene Repair Oligonucleotide (GRON), that is, cleavage of DNA in a plant via a chimeric oligonucleotide of DNA and RNA. This is a technique that can introduce mutations without any modification. Other examples include maize in which herbicide resistance and phytic acid content have been reduced by deleting the endogenous gene IPK1 using zinc finger nuclease (see, eg, Nature 459, 437-441 2009); Rice that has been herbicide-tolerant using Cassine (see, for example, Rice, 7, 5 2014).

  Examples of plants to which herbicide tolerance has been imparted by the new breeding technology include soybeans in which the characteristics of a GM rootstock have been imparted to spikelets using a breeding technique using a graft. Specific examples include soybeans in which glyphosate resistance is imparted to non-transgenic soybean scions using Roundup Ready (registered trademark) soybean having glyphosate resistance as a stock (see Weed Technology 2013, 27, 412.). .

  Examples of plants provided with pest resistance are given below.

  Examples of plants to which resistance to lepidopteran insect pests have been imparted by genetic recombination techniques include, for example, delta-endotoxin (δ-endotoxin), an insecticidal protein derived from the soil bacterium Bacillus thuringiensis (hereinafter referred to as Bt bacterium). Maize (Zea mays L.), soybean (Glycine max L.), cotton (Gossypium hirsutum L.), rice (Oryza sativa L.), poplar (Populus sp.), Tomato (Lycopersicon esculentum) into which the encoding gene has been introduced. , Eggplant (Solanum melongena) and sugarcane (Saccharum sp.). Examples of delta-endotoxins that confer resistance to lepidopteran pests include, for example, Cry1A, Cry1Ab, modified Cry1Ab (a partially deleted Cry1Ab), Cry1Ac, Cry1Ab-Ac (a hybrid protein in which Cry1Ab and Cry1Ac are fused), Cry1C, Cry1F, Cry1Fa2 (modified Cry1F), moCry1F (modified Cry1F), Cry1A. 105 (a hybrid protein in which Cry1Ab, Cry1Ac, and Cry1F are fused), Cry2Ab2, Cry2Ae, Cry9C, Vip3A, and Vip3Aa20.

  Examples of plants to which resistance to Coleoptera insects are imparted by genetic recombination techniques include, for example, corn and potato into which a gene encoding a delta-endotoxin that is an insecticidal protein derived from soil bacteria Bt is introduced. . Examples of delta-endotoxins that confer resistance to Coleoptera pests include Cry3A, mCry3A (modified Cry3A), Cry3Bb1, Cry34Ab1, Cry35Ab1, Cry6A, Cry6Aa, and mCry6Aa (modified Cry6Aa).

  Examples of plants that have been given resistance to dipteran pests by genetic recombination technology include, for example, maize into which a synthetic gene encoding a hybrid protein eCry3.1Ab obtained by fusing Cry3A and Cry1Ab derived from the soil bacterium Bt is introduced. (Zea mays L.) and cotton (Gossypium hirsutum L.) into which a gene encoding a tryptic inhibitor CpTI derived from cowpea (Vigna unguiculata) has been introduced. Furthermore, there are poplar and the like into which a gene encoding an API that is a protease inhibitor protein A derived from kwai (Sagittaria sagittifolia) has been introduced, and it shows resistance to a wide range of pests.

  The insecticidal proteins that impart pest resistance to plants include hybrid proteins of the above insecticidal proteins, partially deleted proteins, and modified proteins. Hybrid proteins are made by combining different domains of multiple insecticidal proteins using genetic engineering techniques, and Cry1Ab-Ac and Cry1A. 105 mag is known. As a partially deleted protein, Cry1Ab or the like in which a part of the amino acid sequence is deleted is known. As the modified protein, Cry1Fa2, moCry1F, mCry3A, and the like are known in which one or more amino acids of the natural delta-endotoxin are substituted. The modified protein also includes a case where a non-naturally occurring proteolytic enzyme recognition sequence is inserted into a toxin. For example, Cry3A055 wherein a cathepsin G-recognition sequence is inserted into a Cry3A toxin (WO2003 / 018810) Reference).

  A cotton (event MON88702) into which a modified BT protein Cry51Aa2 (Cry51Aa2.834_16) has been introduced by genetic recombination technology has been developed by Monsanto, and lygus species such as Lygus lineolaris; It is resistant to Thrips eyes, such as genus species.

  Other insecticidal proteins that impart pest resistance to plants by genetic recombination techniques include, for example, insecticidal proteins derived from Bacillus cereus or Bacillus popilliae; plant insecticidal proteins Vip1, Vip2 , Vip3 (Vip3Aa to Vip3Aj, Vip3Ba, Vip3B and Vip3Ca are known as subclasses, and specifically, for example, Vip3Aa20 and Vip3Aa61 are known) and Vip4; Photolabhas luminescence (Photorhabdus luminescens) Insecticidal protein derived from a bacterium such as Photorhabdus spp. Or Xenorhabdus nematophilus such as Xenorhabdus spp., A nematode symbiotic (nematode-colonizing) bacterium; scorpion toxin, spider toxin Toxins produced by animals, including insect-specific neurotoxins, such as bee toxins; Toxins produced by filamentous fungi such as Streptomycetes venom; plant lectins such as pea lectin, barley lectin, snowdrop lectin; agglutinin; proteases such as trypsin inhibitor, serine protease inhibitor, patatin, cystatin, papain inhibitor Inhibitors; ribosome-inactivating proteins (RIP) such as ricin, corn-RIP, abrin, ruffin, saporin, bryodin; steroids such as 3-hydroxysteroid oxidase, ecdysteroid-UDP-glucosyltransferase, cholesterol oxidase Metabolic enzymes; ecdysone inhibitors; HMG-CoA-reductase; ion channel inhibitors such as sodium channel inhibitors and calcium channel inhibitors; juvenile hormone esterase; diuretic hormone Receptor; stilbene synthase; bibenzyl synthase; chitinase; and glucanase.

  In addition, plants to which pest resistance has been imparted by introducing one or more insecticidal protein genes are already known, and some plants are commercially available.

  Examples of cotton provided with pest resistance include `` Bollgard (TM) cotton '', `` BXN (TM) Plus Bollgard (TM) Cotton '', and `` BXN (TM) Plus '' that express the insecticidal protein Cry1Ac derived from Bt bacteria. Bollgard (trademark) Cotton, JK1, Roundup Ready (trademark) Bollgard (trademark) Cotton and Ingard (trademark); Herculex (expressing insect-killing protein-modified Cry1F (Cry1Fa2) derived from Bt bacterium (Cry1Fa2) (Trademark) I "and" Herculex (trademark) CB ";" VIPCOT (trademark) Cotton "expressing the insecticidal protein Vip3A derived from Bt bacteria;" Bollgard II (trademark) expressing the insecticidal proteins Cry1Ac and Cry2Ab derived from Bt bacteria " ) cotton, Roundup Ready (trademark) Bollgard II (trademark) Cotton, Roundup Ready (trademark) Flex (trademark) Bollgard II (trademark) Cotton, and Fibermax (trademark) Liberty Link (trademark) Bollgard II (trademark) ) ";" Bollgard III (registered trademark) expressing the insecticidal proteins Cry1Ac, Cry2Ab and Vip3A derived from Bt bacteria. "And" Bollgard (R) III x Roundup Ready (TM) Flex (TM) ";" VIPCOT (TM) Roundup Ready Flex (TM) Cotton "expressing insecticidal proteins Vip3A and Cry1Ab from Bt bacteria; Bt bacteria "VIPCOT (registered trademark) Cotton" expressing insecticidal proteins Vip3A and Cry1Ac from the strain; "WideStrike (trademark) Cotton", "WideStrike (trademark) Roundup Ready (trademark) expressing the insecticidal proteins Cry1Ac and Cry1F derived from Bt bacteria. ) Cotton "and" Widestrike (TM) Roundup Ready Flex (TM) Cotton ";" TwinLink (TM) Cotton "and" Glytol (TM) x Twinlink (TM) "expressing insecticidal proteins Cry1Ab and Cry2Ae from Bt bacteria. "Widestrike (registered trademark) 3" and "Widestrike (trademark) x Roundup Ready Flex (trademark) x VIPCOT (trademark) Cotton" expressing insecticidal proteins Cry1Ac, Cry1F and Vip3A derived from Bt bacterium; Glytol® expressing the Cry1Ab, Cry2Ae and Vip3A x Twinlink ™ x VIPCOT ™ Cotton ”, which are commercially available.

  As examples of corn imparted with insect resistance, `` YieldGard (registered trademark) Rootworm RW '' expressing the insecticidal protein Cry3Bb1 derived from Bt bacteria, `` YieldGard (TM) RW + RR '', `` YieldGard (TM) VT ( ™ Rootworm ™ RR2 ”and“ MaxGard ™ ”;“ YieldGard® VT Triple ”and“ YieldGard ™ Plus with RR ”expressing the insecticidal proteins Cry3Bb1 and Cry1Ab from Bt bacteria; Bt "Bt Xtra (trademark) Maize" expressing the insecticidal protein Cry1Ac derived from fungi; "YieldGard Plus (registered trademark)" expressing the insecticidal proteins Cry1Ab and Cry3Bb1 derived from Bt bacteria; "Bt10", "Liberty Link (trademark) Yieldgard (trademark) Maize", "Agrisure (trademark) GT / CB / LL" and "YieldGard (trademark) CB + RR"; insecticidal protein Cry1A derived from Bt bacterium. "YieldGard (TM) VT Pro (TM)" and "Genuity (TM) VT Double Pro (TM)" expressing 105 and Cry2Ab2; "Agrisure (TM) RW expressing the insecticidal protein mCry3A from Bt bacteria. "And" Agrisure (TM) GT / RW ";" Starlink (TM) Maize "expressing the insecticidal protein Cry9C from Bt bacteria;" YieldGard (TM) "expressing the insecticidal protein Cry1Ab from Bt bacteria," MaizeGard (TM), NaturGard KnockOut (TM), Maximizer (TM), Roundup Ready (TM) YieldGard (TM) maize, Agrisure (TM) CB / LL and Mavera (TM) YieldGard (Trademark) Maize ";" Agrisure (registered trademark) 3122 "expressing insecticidal proteins Cry1Ab, Cry1F, modified Cry3A, Cyr34Ab1, and Cyr35Ab1 derived from Bt bacteria;" Agrisure (registered trademark) expressing insecticidal protein Vip3Aa20 derived from Bt bacteria " "Agri" expressing insecticidal proteins Vip3Aa20 and Cry1Ab from Bt strain sure (registered trademark) Viptera (trademark) 2100 '' and `` Agrisure (registered trademark) Viptera (trademark) 3110 ''; `` Agrisure (registered trademark) Viptera (trademark) Agrisure® Viptera® 3111) and Agrisure® Viptera® 4; Agrisure (expressing the insecticidal proteins Vip3Aa20, Cry1Ab and modified Cry1F from Bt bacteria). (Registered trademark) Viptera (trademark) 3220 ";" Agrisure (registered trademark) Duracade (trademark) "expressing insecticidal protein eCry3.1Ab (a chimeric protein of Cry3A-Cry1Ab) derived from Bt bacterium; insecticidal protein derived from Bt bacterium eCry3.1Ab (a chimeric protein of Cry3A-Cry1Ab), `` Agrisure (registered trademark) Duracade (trademark) 5122 '' expressing modified Cry3A, Cry1Ab and modified Cry1F; insecticidal protein eCry3.1Ab (of Cry3A-Cry1Ab derived from Bt bacterium) Chimeric protein), modified Cry3A, modified Cry1Ab and Vip3A variants “Agrisure® Duracade® 5222”; “Herculex® RW” expressing insecticidal proteins Cyr34Ab1 and Cyr35Ab1 from Bt bacteria; expressing insecticidal proteins Cyr34Ab1, Cyr35Ab1 and Cry1F from Bt bacteria “Herculex XTRA ™”; insecticidal protein Cry1A from Bt bacterium. 105, “Genuity® VT Triple Pro ™” expressing Cry2Ab2 and Cry3Bb1; insecticidal proteins Cry1F, Cry2Ab, Cyr34Ab1, Cyr35Ab1, Cry3Bb1, and Cry1A. "Genuity (R) SmartStax (R)" expressing 105; modified insecticidal proteins Cry1F, Cry2Ab and Cry1A. "Power Core (trademark) expressing 105;" Herculex XTRA (trademark) RR "expressing insecticidal protein modified Cry1F, Cyr34Ab1 and Cyr35Ab1 from Bt bacterium; insecticidal protein modified Cry1F, Cyr34Ab1, Cyr35Ab1 from Bt bacterium `` Optimum (registered trademark) Intrasect Xtreme '' expressing Cry1Ab and modified Cry3A; `` Optimum (registered trademark) Intrasect XTRA '' expressing insecticidal protein modified Cry1F, Cyr34Ab1, Cyr35Ab1 and Cry1Ab derived from Bt bacterium; "Optimum (R) TRIsect", which expresses the modified insecticidal proteins Cry1F and Cyr3A, is commercially available.

  As examples of plants that have been imparted with other pest resistance, potatoes expressing the insecticidal protein Cry3A derived from Bt bacteria `` Atlantic NewLeaf (TM) potato '', `` NewLeaf (TM) Russet Burbank potato '', `` Lugovskoi plus '', "Elizaveta plus", "Hi-Lite NewLeaf (trademark) Y potato, Superior NewLeaf (trademark) potato" and "Shepody NewLeaf (trademark) Y potato"; rice plants expressing insecticidal proteins Cry1Ab and Cry1Ac from Bt bacteria "hanyou 63 ”and“ Huahui-1 ”; soybean“ Intacta ™ Roundup Ready ™ 2 Pro ”expressing the insecticidal protein Cry1Ac from Bt bacteria; eggplant“ BARI Bt expressing the insecticidal protein Cry1Ac from Bt bacteria ” Begun-1, -2, -3 and -4 ", which are commercially available.

  In addition, corn having resistance to corn root worm “YieldGard corn rootworm”, “YieldGard VT”, “Herculex RW”, “Herculex Rootworm” and “Agrisure CRW”; corn having resistance to corn borer “YieldGard corn borer” , "YieldGard plus", "YieldGard VT Pro", "Agrisure CB / LL", "Agrisure 3000GT", "Hercules I", "Hercules II", "KnockOut", "NatureGard" and "StarLink"; Western Bean Cut Worm , "Herculex I", "Herculex Xtra", "NewLeaf", "NewLeaf Y" and "NewLeaf Plus" corn with resistance to corn borer, black cut worm and fall army worm; resistance to corn borer and corn root worm "YieldGard Plus", a corn with a resistance; cotton "Bollg," which has resistance to Tobacco ard I "and" Bollgard II "; cotton" Bollgard II "," WideStrike (TM) "which has resistance to fake tobacco, cotton ball worm, fall army worm, beat army worm, cabbage looper, soy looper and pink ball worm. And "VipCot"; potatoes "NewLeaf", "NewLeaf Y" and "NewLeaf Plus" having tobacco tobacco resistance; eggplants "Bt brinjal", "Dumaguete Long Purple" having resistance to eggplant worms, fruit bowlers and cotton ball worms "And" Mara "(see, for example, US5128130).

  Further plants having pest resistance are generally known, for example, Sankameiga-resistant rice (see, for example, Molecular Breeding, Vol. 18 (2006), No. 1), Lepidoptera-resistant lettuce (for example, US5349124), and rice (for example, see WO2001 / 021821) having resistance to Lepidoptera (for example, Japanese squirrels, Ichimonediseri, Rice armyworm, Konomeigame, rice case worm, and rice army worm). Methods for producing such plants are generally known to those skilled in the art and are described, for example, in the above publications.

  As plants to which pest resistance has been imparted by RNA interference technology, lepidopteran pests (for example, cutworms such as corn borers, corn ear worms, black cut worms and fall army worms) and Coleoptera pests (corn rootworms) Corn which is resistant to) is marketed or developed under the trade name of "SmartStax (registered trademark)", "SmartStax (registered trademark) Pro" or "Genuity (registered trademark) SmartStax Pro".

  As a plant to which pest resistance has been imparted by a conventional breeding technique or genomic breeding technique, for example, an aphid resistance gene “Rag1 (Resistance to Aphis glycines 1)” gene or “Rag2 (Resistance to Aphis glycines)” 2) A soybean resistant to the soybean aphid (Aphis glycines) having the gene (see J. Econ. Entomol., 2015, 108, 326.); a soybean resistant to the soybean cyst nematode (Heterodera glycines) (Phytopathology) , 2016, 106, 1444.); Cotton (J. Nematol., 2009, 41, 140) resistant to root-knot nematode (Meloidogyne incognita); Rice “Kanto BPH1” resistant to brown planthopper; Soybean "Fukuminori" which shows resistance is mentioned.

  These plants imparted with pest resistance are given resistance to any harmful insects (especially lepidopterous insects, Coleoptera insects, Diptera insects, Coleoptera insects), harmful spiders and harmful nematodes. Have been. The plant imparted with pest resistance is preferably a barley (eg, wheat, barley, rye, oat), corn, canola, sorghum, soybean, rice, rape, sugar beet, sugar cane, grape, lentil, sunflower, alfalfa, Nuts, drupes, peanuts, coffee, tea, strawberries, grass, vegetables (e.g., tomatoes, potatoes, cucurbits and lettuce), more preferably soybeans, corn, tomatoes, rice and wheat. (Eg, wheat, barley, rye and oat), most preferably soybeans, rice, corn and oats (eg, wheat, barley, rye and oat).

  Examples of plants to which disease resistance has been imparted are described below.

  Plants conferred disease resistance by genetic recombination techniques, for example, express so-called `` pathogenicity-related proteins '' (PRP, see, for example, EP0392225) or so-called `` antifungal proteins '' (AFP, see, for example, US6864068) Plant. Various antifungal proteins having activity against phytopathogenic fungi have been isolated from specific plant species and become common knowledge. Examples of such antipathogenic substances and plants capable of synthesizing such antipathogenic substances are known, for example, from EP0392225, WO1993 / 05153, WO1995 / 33818 and EP0353191. Plants that have resistance to fungicidal pathogens, viral and bacterial pathogens are created by introducing a disease resistance gene. A number of resistance genes have been identified and isolated and used to improve disease resistance, such as tobacco mosaic virus (TMV) resistant tobacco plants N gene introduced into tobacco lines susceptible to TMV (see, for example, US Pat.No. 5,571,706), Prf gene introduced into plants to obtain enhanced pathogen resistance (see, for example, WO 1998/02545), And the Rps2 gene from Arabidopsis thaliana (see, for example, WO1995 / 028423) which has been used to create resistance to bacterial pathogens such as Pseudomonas syringae. Plants exhibiting a systemic acquired resistance response have been obtained by introducing a nucleic acid molecule encoding the TIR domain of the N gene (see, for example, US 6630618). Further examples of known resistance genes include the Xa21 gene that has been introduced into a number of rice varieties (see, for example, US5952485, US5977434, WO1999 / 009151, WO1996 / 022375), for coletotrichum resistance Rcg1 gene (see, for example, US2006 / 225152), prp1 gene (see, for example, US5859332, WO2008 / 017706), ppv-cp gene that introduces resistance to plumpox virus (see, for example, US PP15,154Ps), P1 gene (see, e.g., US5968828), genes such as Blb1, Blb2, Blb3, RB2 and Rpi-vnt1 to introduce resistance to potato blight (phytophthora infestans) in potatoes (e.g., see US7148397), LRPKml Gene (see, for example, WO1999 / 064600), P1 gene for potato virus Y resistance (see, for example, US5968828), HA5-1 gene (see, for example, US5877403 and US6046384), potato virus X (PVX) , A PIP gene to introduce broad resistance to viruses such as potato virus Y (PVY), potato leaf roll virus (PLRV) (see e.g., EP0707069), and Arabidopsis to obtain fungal resistance Genes such as the NI16 gene, ScaM4 gene and ScaM5 gene (see, for example, US6706952 and EP1018553). In addition, beans that have resistance to Bean golden mosaic virus (hereinafter referred to as BGMV) are plants to which resistance has been imparted by RNA interference technology. (sense and antisense ac1 gene) is introduced to inhibit BGMV resistance by inhibiting synthesis of BGMV replication protein. Methods for producing such plants are generally known to those skilled in the art and are described, for example, in the above publications.

  Examples of antipathogenic substances that can be expressed by such plants include ion channel blockers (sodium channel blockers, calcium channel blockers, etc.); viral KP1, KP4 and KP6 toxins; stilbene synthase; bibenzyl synthase So-called “pathogenicity-related proteins” (PRP; see, for example, EP0392225); antipathogenic substances produced by microorganisms (eg, peptide antibiotics, heterocyclic antibiotics (eg, WO1995 / 033818; And protein factors or polypeptide factors involved in the defense of plant pathogens (so-called “plant disease resistance genes” described in WO2003 / 000906)).

  Antipathogenic substances produced by plants can protect plants from various pathogenic microorganisms such as fungi, viruses and bacteria. Useful plants of increasing interest in connection with the present invention include wheat (e.g., wheat, barley, rye and oat), soybean, corn, rice, rapeseed, nuts, drupes, peanuts, coffee, tea, strawberries. Vines and vegetables (e.g., tomatoes, potatoes), cucurbits, papayas, melons, lentils (lenses) and lettuce, more preferably soybeans, tomatoes, rice and barley (e.g., wheat, barley, Rye and oat), most preferably soybeans, rice and barley (eg, wheat, barley, rye and oat).

  Plants having resistance to fungal pathogens include, for example, soybeans having resistance to soybean rust (Phakopsora pachyrhizi and Phakopsora meibomiae) (see, for example, WO2008 / 017706); and phytophthora infestans. Solanaceous plants such as cotton, tomato, potato and the like (see, for example, US5859332, US7148397, EP1334979); corn (for example, US2006) which is resistant to Colletotrichum such as Colletotrichum graminicola. Apples having resistance to the apple scab (venturia inaequalis) (see, for example, WO1999 / 064600); Fusarium species (for example, fusarium graminearum, fusarium sporotrichioides, fusarium lateritium, fusarium pseudograminearum, fusarium sambucinum, fusarium fusarium) culmorum, fusarium poae, fusarium acuminatum, fusarium equiseti) (eg, rice, wheat, barley, rye, corn, oat, potato, melon, soybean and sorghum) (see, eg, US Pat. No. 6,646,184, EP1477557); has a wide range of fungicidal resistance Plants such as corn, soybean, barley (especially wheat, barley, rye, and oat) rice, tobacco, sorghum, sugarcane, potato, and the like (see, for example, US5859332, US5689046, US6706952, EP1018553, and US6020129).

  Examples of plants having resistance to bacterial pathogens include, for example, rice having resistance to xylella fastidiosa (see, for example, US6232528); rice, cotton having resistance to bacterial canker, and the like. Plants such as soybean, potato, sorghum, corn, wheat, barley, sugarcane, tomato and pepper (see, for example, WO2006 / 42145, US5952485, US5977434, WO1999 / 09151, WO1996 / 22375); against Pseudomonas syringae Resistance tomato (see, for example, Can. J. Plant Path., 1983, 5: 251-255).

  Examples of plants having resistance to viral pathogens include, for example, drupes having resistance to plum pox virus (for example, plum, almond, apricot, cherry, peach, nectarine) (for example, US PP15154Ps, Potato virus Y (see, for example, US5968828); potato, tomato, cucumber resistant to tomato spotted wilt virus And plants such as legumes (see, for example, EP0626449, US5973135); corn having resistance to maize streak virus (see, for example, US6040496); papaya ring spot virus (papaya ring spot virus). papaya (see, for example, S5877403, US6046384); cucumber mosaic Cucurbitaceous plants (eg, cucumber, melon, watermelon, and pumpkin) and solanaceous plants (eg, potato, tobacco, tomato, eggplant, paprika, pepper, and pepper) having resistance to cucumber mosaic virus (eg, US6849780) Cucumber plants (e.g., cucumber, melon, watermelon, and pumpkin) having resistance to watermelon mosaic virus 2 and zucchini yellow mosaic virus (see, e.g., US6015942); Potato leaf roll virus (potatoes having potato leafroll virus resistance (see, for example, US5576202); viruses such as potato virus X (potato virus X), potato virus Y (potato virus Y), potato leaf roll virus (potato leafroll virus) Potatoes with broad resistance to See, for example, EP0707069); kidney beans that are resistant to Bean golden mosaic virus (see, for example, Mol Plant Microbe Interact. 2007 Jun; 20 (6): 717-26.). No.

  There are plants that are resistant to antibiotics (eg, kanamycin, neomycin, and ampicillin). The naturally occurring bacterial nptII gene expresses an enzyme that blocks the action of the antibiotics kanamycin and neomycin. The ampicillin resistance gene, ampR (also known as blaTEM1), is derived from the bacterium Salmonella paratyphi and is used as a marker gene in the transformation of microorganisms and plants. ampR is involved in the synthesis of beta-lactamases, enzymes that neutralize penicillin group antibiotics, including ampicillin. Plants having resistance to antibiotics include, for example, potatoes, tomatoes, flax, canola, rapeseed, rapeseed seeds and corn (e.g., Plant Cell Reports, 20, 2001, 610-615, Trends in Plant Science, 11, 2006, 317-319, Plant Molecular Biology, 37, 1998, 287-296, Mol Gen Genet., 257, 1998, 606-13.Plant Cell Reports, 6, 1987, 333-336, Federal Register (USA), Volume 60, No. 113, 1995, p. 31139. Federal Register (USA), Volume 67, No. 226, 2002, p. 70392, Federal Register (USA), Volume 63, No. 88, 1998, 25194, Federal Register (USA), Volume 60, No. 141, 1995, 37870, Canadian Food Inspection Agency, FD / OFB-095-264-A, October 1999, FD / OFB-099-127-A, October 1999). Preferably, said plant is selected from soybeans, tomatoes and barley (e.g., wheat, barley, rye and oat), most preferably selected from soybeans and barley (e.g., wheat, barley, rye and oat). You.

  Available plants that have been given resistance to plant virus diseases include, for example, papaya “Rainbow”, “SunUp” and “Huanong No. 1 that have been given resistance to Papaya ringspot virus. Potatoes "Innate (R) Hibernate", "Innate (R) Glaciate" and "Innate (R) Acclimate" exhibiting resistance to potato plague (phytophthora infestans); Potato virus Y and / or potato cigar Potato “Newleaf ™” which shows resistance to the virus (PLRV).

  As a plant to which disease resistance has been imparted by a conventional breeding technique or genome breeding technique, a rice which has been imparted with resistance to blast; a rice which has been imparted with resistance to sheath blight Wheat conferred with resistance to leaf rust; Wheat conferred with resistance to stripe rust; Wheat conferred with resistance to stem rust; Wheat conferred resistance to powdery mildew; wheat conferred resistance to leaf blotch; wheat conferred resistance to glume blotch; Wheat conferred resistance to tan spot; Barley conferred resistance to powdery mildew; Barley conferred resistance to dwarf leaf rust; Barley conferred resistance to net blotch; barley conferred resistance to scald; barley conferred resistance to Ramularia leaf spot disease; Anthracnose Corn); corn which has been given resistance to gray leaf spot; corn which has been given resistance to Goss's wilt disease (Goss's wilt); fusarium stalk rot Corn that has been given resistance to Fusarium stalk rot; soybean that has been given resistance to Asian soybean rust; soybean that has been given resistance to phytophthora stem and root rot Soybean with resistance to sudden death syndrome; against soybean disease (Phytophthora rot) Pepper with resistance; lettuce with resistance to powdery mildew; tomato with resistance to bacterial wilt; resistance to Gemini virus Tomatoes given; lettuce given resistance to downy mildew; rapeseed, cabbage, brussels sprouts, cauliflower, colored green (Borekale), broccoli, etc. given resistance to clubroot Cruciferous plants; rapeseed, cabbage, brussels sprouts, cauliflower, colored green (Borekale), broccoli and other cruciferous plants imparted with resistance to canker (black leg); melons caused by Fusarium oxysporum f.sp. melonis Melon (for example, see WO2009 / 000736) which has been imparted with resistance to Fusarium wilt.

  As a plant to which disease resistance has been imparted by genome editing technology, the powdery mildew resistance gene (MILDEW RESISTACE LOCUS O, hereinafter abbreviated as MLO) is deleted using turren and crisper cassine Bread wheat resistant to powdery mildew (see, for example, Nat. Biotech., 32, 947-951 2014); by using Crisper Cassine to delete the SlMLO1 gene, one of the MLOs, Slmlo1 tomato (Tomelo) showing resistance to powdery mildew (see, for example, Scientific Reports 7, Article number: 482 2017); by using the tallen to edit the OsSWEET14 gene in rice, Rice resistant to Xanthomonas oryzae pv. Oryzae causing bacterial leaf blight (see Nat. Biotechnol. 30, 390-392 2012); using Crispar Cassine Rice (PLoS ONE 11: e0154027. Doi: 10.1371 / journal.pone.0154027 2016) which shows resistance to Magnaporthe oryzae which causes blast by modifying the OsERF922 gene in rice Cucumber vein yellow ining virus (CVYV), zucchini yellow mosaic virus (ZYMV), papaya ringspot virus-typeW (PRSV) by disrupting the recessive eIF4E (eukaryotic translation initiation factor 4E) gene using Crisper Cassine. -W) resistant cucumber (see Mol. PlantPathol. 17, 7 1140-1153 2016); caused by Phytophthora sojae by disrupting the RXLR effector gene (Avr4 / 6) using Crisper Cassine Soybean (see Mol Plant Pathol 17 (1) 127-139 2016) that is resistant to phytophthora stem and root rot.

  Introduced Rvi6 (formerly called HcrVf2) gene, which is resistant to Apple scab caused by Venturia inaequalis, using cisgenesis as a plant that has been given disease resistance by new breeding technology Apples resistant to mold blight disease (see, for example, Plant Biotech. J., 12, 2-9, 2014); Examples of giving GM rootstocks, which is a breeding technology using grafting, to spikelets Sweet cherry (Plant Biotech. J., 12, 1319-), which has transferred its properties from transgenic rootstocks resistant to infection of Prunus necrotic ringspot virus to non-transgenic scions. 1328 2014).

  Examples of plants with altered product quality are given below.

  By modifying the quality of the product is meant synthesis of the modified component or an increase or decrease in the amount of the component compared to the corresponding wild-type plant. Plants with altered product quality include, for example, modified plants with increased or decreased content of vitamins, amino acids, proteins and starch, various oils, and modified plants with reduced nicotine content.

  Plants whose product quality has been modified by genetic recombination techniques include, for example, a double chain of alfalfa-derived S-adenosyl-L-methionine: trans-caffeoyl-CoA3-methyltransferase (ccomt) gene involved in lignin production. Alfalfa whose lignin content has been reduced by RNA interference by introducing a gene that produces RNA; triacylglycerides containing lauric acid by introducing a 12: 0 ACP thioesterase gene from Laurier (Umbellularia californica) involved in fatty acid synthesis An increased content of canola "Laurical (trademark) Canola"; suppresses the gene expression by introducing a partial gene (gm-fad2-1) of ω-6 desaturase derived from soybean, which is a fatty acid desaturase, Soy "Plenish (TM)" and "Treus (TM)" with increased oleic acid content; A double-stranded RNA of a soybean-derived acyl-acyl carrier protein thioesterase gene (fatb1-A) and a double-stranded RNA of a soybean-derived δ-12 desaturase gene (fad2-1A) Soybean "Vistive Gold (TM)" whose saturated fatty acid content has been reduced by introducing the gene; a primrose delta-6 desaturase gene (Pj.D6D) and a Neurospora crassa-derived delta-12 desaturase gene (Nc.Fad3). Genetically modified soybean in which one of the omega-3 fatty acids, stearidonic acid, has been produced by the introduction; biotransformation by introducing the thermostable alpha-amylase gene (amy797E) of Thermococcales sp. Corn “Enogen®” with enhanced production of ethanol; Maize "Mavera (TM) Maize" and "Mavera (TM) YieldGard (TM) Maize", which have increased lysine production by introducing a dihydrodipicolinate synthase gene (cordapA) from Corynebacterium glutamicum A potato "Amflora (trademark)" in which the amylose content in starch granules was reduced and the amylopectin content was increased by introducing the antisense gene gbss of potato-derived starch synthase (granule-bound starch synthase enzame, GBSS); , "Starch Potato"; two genes, Asn1 related to suppression of starch degradation and production of asparagine by introducing genes pPhL and pR1 that generate double-stranded RNA of transcription factor genes PhL and R1 that promote the degradation of potato-derived starch. Inhibition of asparagine synthesis by introducing the gene asn1 that produces heavy-chain RNA (carcinogenic substance by heating) (In order to suppress the accumulation of asparagine and reducing sugars involved in the production of acrylamide) and the potato-derived polyphenol oxidase gene ppo5, which is a double-stranded RNA-gene ppo5. (Registered trademark) Cultivate "," Innate (registered trademark) Generate "," Innate (registered trademark) Accelerate "," Innate (registered trademark) Invigorate "," Innate (registered trademark) Glaciate "," Innate (registered trademark) Acclimate " And "Innate (registered trademark) Hibernate"; tobacco whose nicotine content has been reduced by introducing an antisense gene (NtQPT1) of the quinolinate phosphoribosyltransferase gene QpTase derived from tobacco (Nicotiana tabacum); Narcissus pseudonarcissus ) -Derived phytoene synthase gene (psy) and soil that synthesizes carotenoids Golden, a rice that can produce β-carotene in endosperm tissue and harvest rice containing vitamin A by introducing a carotene desaturase gene (crt1) from the bacterium Erwinia uredovora and expressing it endosperm-specifically Rice (Golden rice). In addition, for example, potatoes and corns with modified amylopectin content (see, eg, US6784338, US2007 / 0261136, WO1997 / 04471); canola, corn, cotton, grape, cattail with modified oil content , Cowpea (catalpa), rice, soybean, oilseed rape, wheat, sunflower, bitter melon, safflower (safflower) and plants of the genus Vernonia (e.g., US7294759, US7157621, US5850026, US6441278, US5723761, US6380462, US6365802, US6974898, 2001) / 079499, US2006 / 0075515 and US7294759); sunflower with increased fatty acid content (see eg US6084164); soybean with reduced allergen content (see eg US6864362); tobacco with reduced nicotine content (see US6864362) See, for example, US2006 / 0185684, WO2005 / 000352 and WO2007 / 064636); canola and soybean with increased lysine content (eg, Bio / Technolog corn and soybeans with altered methionine, leucine, isoleucine and / or valine composition (see, eg, US6946589, US6905877); soybeans with increased sulfur amino acid content (see US Pat. For example, EP0929685, WO1997 / 041239); 3′-Phosphoadenosine-5′-phosphosulfate reductase derived from Escherichia coli (3′-Phosphoadenosine-5′-phosphosulfate reductase) is specifically expressed on the leaf surface. Corn with increased methionine content (see PNAS, 2017, 114 (43), 11386.); increased free amino acids (eg, asparagine, aspartic acid, serine, threonine, alanine, histidine and glutamic acid) Tomato (see, for example, US6727411); Corn with increased amino acid content (see, for example, WO 05/077117); Potato, corn with modified starch content Kosi and rice (see, for example, WO1997 / 044471 and US7317146); tomato, corn, grape, alfalfa, apple, legumes and pea with altered flavonoid content (see, for example, WO00 / 04175); phenolic compounds Corn, rice, sorghum, cotton and soybean with altered content (see, for example, US 2008/0235829); tomato and canola with increased vitamin A content (see, for example, US 6797498, US 7348167); Vitamin E content Increased amounts of tomato, canola, soybean, wheat, sunflower, rice, corn, barley and rye (see, eg, US7348167, WO2004 / 058934); alfalfa, apple, legume, corn, grape with altered flavonoid content , Tomatoes and peas (see, for example, WO 00/04175). Methods for producing such plants are generally known to those skilled in the art and are described, for example, in the publications mentioned above. Preferably, the plant is selected from soybean, canola, tomatoes, rice and varieties (eg wheat, barley, rye and oat), most preferably from soybean, canola, rice, wheat and barley.

  Rapeseed "Nexera (R) Canola" producing unsaturated omega-9 fatty acids as a plant whose product quality has been modified by conventional breeding techniques or genomic breeding techniques; soybean with reduced allergen content “Yumeminori”: Rice for the purpose of modifying to a good taste, for example, rice with a reduced amylose content “Yumepurika” is commercially available. Also, citrus in which properties of fruits (for example, the weight of the fruits, the degree of aroma, the juiciness, and the sugar content) thereof are modified by genomic selection is known (see Scientific Reports 7, 4721 2017).

  Examples of the plant in which the nutrient utilization of the plant has been modified include a plant in which assimilation or metabolism of nitrogen or phosphorus is enhanced. Plants having enhanced nitrogen assimilation ability and nitrogen utilization ability by genetic recombination technology include, for example, canola, corn, wheat, sunflower, rice, tobacco, soybean, cotton, alfalfa, tomato, wheat, potato, sugar beet, sugarcane and Rapeseed (see, for example, WO1995 / 009911, WO1997 / 030163, US6084153, US5955651, and US6864405). Examples of plants in which phosphorus uptake has been improved by genetic recombination techniques include, for example, alfalfa, barley, canola, corn, cotton, tomato, rapeseed, rice, soybean, sugar beet, sugarcane, sunflower, wheat, and potato (for example, See US7417181, US2005 / 0137386). Methods for producing such plants are generally known to those skilled in the art and are described, for example, in the publications mentioned above. Preferably, the plant is selected from soy, tomato and barley (eg, wheat, barley, rye and oat), most preferably from soy, rice, corn and wheat.

  Plants in which fertility traits and the like have been modified by genetic recombination techniques include plants in which male sterility and fertility restoration traits have been imparted to the plant. For example, maize and chicory which have been given a male sterility trait by expressing a ribonuclease gene (barnase) derived from Bacillus amyloliquefaciens in anther tapetum cells; a DNA adenine methylase gene (dam) derived from Escherichia coli; Maize to which a male sterility trait has been imparted by introduction; a maize-derived alpha-amylase gene (zm-aa1) that provides a male sterility trait and a maize-derived ms45 protein gene (ms45) that provides a fertility restoration trait Maize whose fertility traits have been controlled by cultivation; canola conferred with fertility restoring function by expressing a Bacillus-derived ribonuclease inhibitory protein gene (barstar) in anther tapetum cells; bacillus conferring a male sterility trait Ribonuclease gene (b) arnase) and canola in which the fertility trait is controlled by expressing a ribonuclease-inhibiting protein gene (barstar) derived from Bacillus that gives the fertility restoring trait. Other plants to which the fertility trait has been imparted by genetic recombination techniques include tomato, rice, mustard, wheat, soybean and sunflower (e.g., US6720481, US6281348, US5659124, US6399856, US7345222, US7230168, US6072102, EP1135982, WO2001. / 092544 and WO1996 / 040949). Methods for producing such plants are generally known to those skilled in the art and are described, for example, in the publications mentioned above. Preferably, the plant is selected from corn, canola, soybean, rice, tomatoes and oats (eg wheat), most preferably from corn, canola, soybean, rice, wheat.

  Plants conferred abiotic stress tolerance can be drought, high salinity, high light intensity, high UV irradiation, chemical contamination (eg, high heavy metal concentrations), low or high temperatures, and limited nutrients (ie, nitrogen, phosphorus). Plants that show increased tolerance to abiotic stress conditions such as feeding and population stress (see, eg, WO 2000/004173, WO 2007/131699, CA2521729 and US2008 / 0229448).

  Examples of plants to which abiotic stress resistance has been imparted by genetic recombination techniques include, for example, rice, corn, soybean, sugarcane, alfalfa, wheat, tomato, potato, barley, rapeseed, legume, oat, sorghum, which are resistant to drought. And cotton (see, for example, WO2005 / 048693, WO2008 / 002480 and WO2007 / 030001); corn, soybean, wheat, cotton, rice, rapeseed and alfalfa that are resistant to low temperatures (see, for example, US4731499 and WO2007 / 112122) Rice, cotton, potato, soybean, wheat, barley, rye, sorghum, alfalfa, grape, tomato, sunflower and tobacco (see, for example, US7256326, US7034139, WO / 2001/030990) which are resistant to high salinity. . There is also a corn “DroughtGard (registered trademark)” (product of Monsanto) into which the cold shock protein gene cspB of Bacillus subtilis has been introduced.

  As a plant to which abiotic stress tolerance has been imparted by a conventional breeding technique or a genomic breeding technique, for example, corn having drought tolerance includes "Agrisure Artesian (registered trademark)" and "Optimum ( (Registered trademark) AQUAmax (registered trademark) ".

  As a plant to which other characteristics are imparted, there is a plant whose maturation characteristics are modified. Modification of maturation properties includes, for example, delayed ripening, delayed softening, and early maturation. Plants whose maturation properties have been modified by genetic recombination techniques, for example, by introducing the S-adenosylmethione hydrolase gene (sam-K) derived from Escherichia coli bacteriophage T3 for the production of the plant hormone ethylene, can maintain shelf life. Improved melon and tomato; a gene lacking a part of the tomato-derived ACC synthase gene involved in the production of the plant hormone ethylene; an ACC deaminase gene derived from Pseudomonas chlororaphis, which degrades ACC, an ethylene precursor; Shelf by introducing at least one of a tomato-derived polygalacturonase gene double-stranded RNA gene that degrades cell wall pectin or a tomato-derived ACC oxidase gene involved in ethylene production. Tomato with improved durability; polygalacturonase from tomato Include tomatoes was improved shelf-life "FLAVR SAVR (trademark)" by introducing a gene pg to generate a double-stranded RNA of the child. Other plants whose maturation characteristics have been modified by genetic recombination techniques include, for example, tomato, melon, raspberry, strawberry, muskmelon, pepper and papaya whose ripening has been delayed (for example, US5767376, US7084321, US6107548). , US5981831, WO1995 / 035387, US5952546, US5512466, WO1997 / 001952, WO1992 / 008798 and Plant Cell. 1989, 53-63; see Plant Molecular Biology, 50, 2002). Methods for producing such plants are generally known to those skilled in the art and are described, for example, in the publications mentioned above. Preferably, the plant is a fruit (e.g., tomato, vine, melon, papaya, banana, pepper, raspberry and strawberry); drupes (e.g., cherries, apricots and peaches); nuts (e.g., apples and medusa) Pear); and selected from citrus fruits (e.g., citron, lime, orange, pomelo, grapefruit, and mandarin), more preferably selected from tomato, melon, papaya, vine, apple, banana, orange, and strawberry; Most preferred are tomato, melon and papaya.

  Plants that have been given other quality modifications by genetic recombination techniques include, for example, endogenous plants by introducing a 3-phytase gene (phyA) derived from Aspergillus niger, a phytic acid-degrading enzyme of plants. A canola “Phytaseed (registered trademark) Canola” in which the degradation of phytic acid is enhanced; a dihydroflavonol-4-reductase gene derived from petunia (Petunia hybrida), which is an enzyme that produces the blue pigment delphinidin and its derivatives; Carnation "Moondust (trademark)", "Moonshadow" whose flower color is controlled to be blue by introducing a flavonoid-3 ', 5'-hydroxylase gene from pansy (Viola wittrockiana), salvia (Salvia splendens) or carnation. (Trademark) "," Moonshade (trademark) "," Moonlite (trademark) "," Moonaqu " a (TM), Moonvista (TM), Moonique (TM), Moonpearl (TM), Moonberry (TM) and Moonvelvet (TM); Produces the blue pigment delphinidin and its derivatives Rose whose flower color was controlled to be blue by introducing an anthocyanin-5-acyltransferase gene derived from Torenia sp. And a flavonoid-3,5'-hydroxylase gene derived from pansy. Rice that has immunity-tolerant hay fever effect by introducing the antigen protein gene (7crp) of the Japanese cedar pollen; enhances the degradation of endogenous phytic acid by introducing the 3-phytase gene (phyA) from black mold Corn; producing high quality fiber with improved fiber micronaire, increased fiber strength, uniform length and color Cotton (see, for example, WO1996 / 26639, US7329802, US6472588 and WO2001 / 17333) can be mentioned.

  Examples of a plant whose traits related to plant growth or yield have been modified include plants having enhanced growth ability. Plants whose traits related to growth and yield have been modified by genetic recombination techniques, for example, by introducing a gene (bbx32) that encodes a transcription factor that controls circadianity derived from Arabidopsis thaliana, enhances plant growth. Soybean with high yield as expected; introduction of a transcription factor gene (athb17) belonging to the homeodomain-leucine 14 zipper (HD-Zip) family class II HD-Zip II) derived from Arabidopsis thaliana As a result, corn that can be expected to have a high yield has been developed.

  As a plant whose quality has been modified by genome editing technology, it lacks the IPK1 gene encoding inositol-1,3,4,5,6-pentakisphosphate 2-kinase, an enzyme for phytic acid biosynthesis, using zinc finger nuclease. Corn "ZFN-12 maize" with reduced phytic acid content by elimination of phenolic acid content; by using Crispar Cassine, the gene encoding polyphenol oxidase is deleted to impart browning resistance. Mushrooms (see, for example, Nature., Vol 532, 21 APRIL 2016).

  Plants whose quality has been modified by the new breeding technology include, for example, using cisgenesis to introduce a low polyphenole oxidase (enzyme that causes browning) production gene sequence GEN-03 isolated from apple into a new apple variety. "Arctic (registered trademark)", an apple with reduced polyphenole oxidase expression and non-browning; An example of giving the properties of a GM rootstock, which is a breeding technology using a graft, to a scion, is a salt-resistant tomato stand. Examples include tomatoes obtained by imparting salt tolerance to tomatoes of non-transgenic spikelets using trees (see Physiol Plantarum, 124, 465-475 2005).

  In rice, genes exhibiting resistance to many diseases, pests and abiotic stress are known, and the production of resistant varieties into which these are introduced is active. Diseases in rice, and genes showing resistance to abiotic stress, for example, BPH1, BPH2, BPH3, BPH4, BPH5, BPH6, BPH7, BPH8, BPH9, BPH10, BPH11, BPH12, BPH13, BPH14, BPH15, BPH17 , BPH18, BPH19, BPH20, BPH21, BPH22, BPH23, BPH24, BPH25, BPH26, BPH27, BPH28, BPH29, BPH32, qBPH-12, qBPHR-1, qBPHR-3, qBPHR-8, qBPHR-5-1qBPHR-5 -2 Brown rice planthopper resistance genes such as qBPHR-11-1 and qBPHR-11-2; seradium planter resistance such as WBPH1, WBPH2, WBPH3, WBPH4, WBPH5, WBPH6, OVC, qOVA-5-2, qOVA1-3, qOVA5-1 Sex genes; QsbH, GL, HGL1H, GsH, HGL1H, GL5H, GLsH, GL5H, GL5H, GL5H, GL5H, GL5H, GL5H, GL5H, GL5H, GL5H, GL5H, GL8H, GL5H, GL8H, GL5H, GL5H, GL8H, GL5H, GL5H, GL5H, GL5H, GL5H, GL5H8H , GLH9, GLH10, GLH11, GLH12, GLH13, GRH1, GRH2, GRH3, GRH4, GRH5, Zlh1, Zlh2, Zlh3, qGRH-4, qGRH-2, qGRH-5, qGRH-6, qGRH-11, qG Leafhopper resistance gene such as RH-3; Rootweed resistance gene such as SB; Pii, PI65, PIZT, PI24, PI29, PI25, Pi-jnw1, PB1, PIQ6, PID3, PI67, PITQ5, PITP, PITQ6, PLM2, PISE3, IPI, PISE1, PI157, PIQ4, PI21, PIA, PIB, PIK, PIKUR1, PIKUR2, PI3, PIF, PIZH, PIR4, PIR7, PI30, PI, PIGD2, PIG, PIGD3, PIGD1, PIZ, PI (, PI18 , PIM, PI17, PI20, PI1, PI19, PI5, PISH, PI10, PI9, PI21, PI22, PI44, PI22, PI13, PII, PIB1, PIQ1, PIQ2, PIQ3, PIIS1, PII2, PI62, PI12, IPI3, PI14 , PI15, PI16, PIT, PI11, PI6, PI23, PI14, PI11, PIIS2, PIB2, PI12, PI39, PI40, PITA, PIR2-3, PIR9-2, PIR12-2, PIRF2-1, qRBR-2, qRBR -3, PI27, PI28, PI26, PIGM, PI47, PI48, PI7, PI56, PI49, PI34, PIKG, PI38, PI32, PI31, PI46, PIX, PIXY, Pita3, PI41, PI42, PI2, PI36, PI37, PIKH , PIKM, PIKP, PI35, PIZ5, PIB2, PI43, PI50, PI51, PID1, PIY1, PIY2, PI55-2, PICO39, PI55-1, PIBH8, PIR7A, PIR7B, PID2, PI33, qBFR4-1, qBFR4-2, qRBR-2, qRBR-3, qRBR-8, qRBR-1-1, qRBR-1-3, qRBR-7-1, qRBR-7-2, qRBR-9- 1, blast resistance genes such as qRBR-9-2, qRBR-9-3, qRBR-1-2, qRBR-1-4; genes against stripe blight resistance such as STVA, STVB, Stvb-i; XA21D, XA, XA40, XANM, XA8, XA33, XA34, XA35, XA36, XA37, XA7, XA3, XA25, XA28, XA29, XA30, XA31, XA32, XA38, XA39, XA11, XA16, XA17, XA18 , XA20, XA14, XA2, XA12, XA1, XAK, XAA, XAH, XA10, XA23, XA22, XA24, XA21, SERRT13, XA4, XA5, XA13 etc .; blight resistance genes such as qSB-3, qSB-7, qSB-11, and qSB-9-1; sesame leaf blight resistance genes such as CE; yellow dwarf disease resistance genes such as YDV; BSV etc. Black streak dwarf disease resistance gene; Amy1A, Amy1C, Amy3A, Amy3B etc. high temperature attendance school resistance genes; dul3, qAC9.3, rsr1, Wx and Wx1-1 etc. low amylose genes; AP01, SCM2, Sd1 etc. Lodging resistance inheritance Offspring resistance genes such as Sdr4; low temperature resistance genes such as CTB1, CTB2, qLTG3-1; drought resistance genes such as Dro1; DEP1, Cn1a, GPS, SPIKE, PTB1, TAWAWA1, WFP, IPA1, GS3, GS5, GS6, GL3.1, GW2, GW8, qGL3, qSS7, qSW5, etc., genes related to paddy number or seed shape; Hd1, Ghd8, DTH8, etc., genes regulating daylength reactivity; FLO4, PDIL1, etc. endosperm powder Sex genes; lipoxygenase-deficient (reduced old rice odor) genes such as LOX3; and genes related to amylopectin chain length such as Alk are known. Rice varieties incorporating one or more of these genes at the same time have been developed or marketed.

  The above-mentioned plants may be subjected to abiotic stress resistance, disease resistance, herbicidal use using genetic recombination technology, conventional breeding technology, genome breeding technology, new breeding technology or genome editing technology, etc. By multiplying two or more strains that have been imparted with drug resistance, pest resistance, growth and yield traits, modification of nutrient utilization, modification of product quality, fertility traits, etc., and plants having the same or different properties Plants to which two or more properties of the parent line have been imparted are also included.

  Commercially available plants that have been rendered resistant to two or more herbicides include, for example, cotton “GlyTol ™ LibertyLink ™” and “GlyTol ™ LibertyLink ™” which are resistant to glyphosate and glufosinate; Maize “Roundup Ready ™ LibertyLink ™ Maize” having glyphosate resistance and glufosinate resistance; soybean “Enlist ™ Soybean” having glufosinate resistance and 2,4-D resistance; soybean having glyphosate resistance and dicamba resistance Genuity® Roundup Ready ™ 2 Xtend ™ ”; maize and soybean“ OptimumGAT ™ ”with glyphosate resistance and ALS inhibitor resistance; glyphosate, glufosinate and 3,4-D herbicides Genetically modified soybeans "Enlist E3 (TM)" and "Enlist (TM) Roundup Ready 2 Yield (R)" that are resistant to Corn “Enlist® Roundup Ready® Corn 2” resistant to rephosate, 2,4-D and allyloxyphenoxypropionic acid (FOPs) herbicides; glyphosate, 2,4-D and allyloxyphenoxy Corn “Enlist® Roundup Ready® Corn 2” resistant to propionic acid (FOPs) herbicides; Cotton “Bollgard II® XtendFlex ™ Cotton resistant to dicamba, glyphosate and glufosinate Cotton "Enlist ™ Cotton" which is resistant to glyphosate, glufosinate and the three herbicides 2,4-D; to three herbicides glyphosate, glufosinate and HPPD herbicides (eg isoxaflutol) The soybean "Liberty Link (registered trademark) GT27 (trademark)" which is resistant is mentioned. In addition, cotton resistant to both glufosinate and 2,4-D; cotton resistant to both glufosinate and dicamba; corn resistant to both glyphosate and 2,4-D; glyphosate and HPPD herbicides Soybeans resistant to both; maize resistant to glyphosate, glufosinate, 2,4-D, allyloxyphenoxypropionic acid (FOPs) and cyclohexadione (DIMs) herbicides have also been developed.

  Commercially available plants provided with herbicide resistance and pest resistance include, for example, corn “YieldGard Roundup Ready ™” and “YieldGard Roundup Ready 2 ™” having glyphosate resistance and resistance to corn borer. Maize "Agrisure CB / LL (TM)" having glufosinate resistance and corn borer resistance; corn "Yield Gard VT Root worm / RR2 (TM)" having glyphosate resistance and corn root worm resistance; Maize “Yield Gard VT Triple ™” having resistance to corn rootworm and corn borer; glufosinate resistance and lepidopteran pest resistance (Cry1F) (eg, Western bean cut worm, corn borer, black cut worm and fall Army worm) Maize "Herculex I (trademark)"; maize "YieldGard Corn Rootworm / Roundup Ready 2 (trademark)" having glyphosate resistance and corn root worm resistance; Maize "Agrisure GT / RW (TM)" having Western corn rootworm, Northern corn rootworm and Mexican corn rootworm); glufosinate resistance and Coleoptera pest resistance (Cry34 / 35Ab1) (for example, Western corn rootworm) Maize "Herculex RW (trademark)", which has resistance to root worms, northern corn root worms and Mexican corn root worms; "Yield Gard VT Root worm / RR2 (trademark), which has glyphosate resistance and corn root worm resistance ) "; Dicamba tolerance, glyphosate Sex, Gurihoshineto resistance and lepidopteran insect resistant cotton (e.g., bollworm acids and tobacco budworm, resistance to such armyworm acids) is cotton "Bollgard (R) 3 XtendFlex (registered trademark)" with.

  Examples of commercially available plants provided with disease resistance and insect resistance include, for example, potato "Hi-Lite NewLeaf (trademark) Y provided with potato virus Y resistance and insect resistance. Potato "," NewLeaf (trademark) Y Russet Burbank Potato "and" Shepody NewLeaf (trademark) Y Potato "; potato" NewLeaf (trademark) Plus provided with potato leafroll virus resistance and pest resistance Russet Burbank Potato ".

  Commercially available plants that have been imparted with herbicide resistance and product quality modifying properties include, for example, canola "InVigor (TM) Canola", which is imparted with glufosinate tolerance and fertility traits; Corn “InVigor ™ Maize”; soybean “Vistive Gold ™” having glyphosate resistance and modified oil content.

  Examples of commercially available plants having three or more traits include glyphosate-tolerant, glufosinate-tolerant and lepidopteran-tolerant (Cry1F) (ie, against Western bean cutworm, corn borer, black cutworm and fall armyworm). Maize "Herculex I / Roundup Ready 2 (TM)" having resistance to glyphosate, corn rootworm and corn borer resistant "YieldGard Plus / Roundup Ready 2 (TM)"; glyphosate resistant, glufosinate Maize "Agrisure GT / CB / LL (TM)" having resistance and corn borer resistance; glufosinate resistance, lepidopteran pest resistance (Cry1F) and Coleoptera pest resistance (Cry34 / 35Ab1) (i.e., western bean cutworm, Corn borer, black cut worm and faller Maize “Herculex Xtra ™” having resistance to lepidopteran pests such as meeworm and Coleoptera pests such as western corn rootworm, northern corn rootworm, and Mexican corn worm; glufosinate resistance, corn borer resistance (Cry1Ab ) And Coleoptera pest resistance (Cry3A) (ie, resistance to western corn rootworm, northern corn rootworm, and Mexican corn rootworm) "Agrisure CB / LL / RW (TM)"; glyphosate resistance, corn borer Maize “Agrisure ™ 3000GT” having resistance (Cry1Ab) and Coleoptera pest resistance (Cry3A) (ie, resistance to western corn rootworm, northern corn rootworm, and Mexican corn rootworm); glyphosate resistance, corn root Corn "Mavera high-value corn" having resistance to corn and European corn borer and high lysine trait; European corn borer, Southwestern cornborer, corn earworm, fall army worm, black cut worm and / or western bean worm Optimum (registered trademark) Leptra (trademark), which has resistance to pests that infest the aerial parts of plants such as glyphosate resistance, glufosinate resistance, soybean spot spot (frogeye leaf spot) resistance, sudden death syndrome (sudden) death Syndrome resistance, southern stem canker resistance, phytophthora stem and root rot resistance, southern root-knot nematode resistance, white rot resistance , Brown stem rot resistance, soybean Soybean "Credenz (R) soybean" having nematode (soybean cyst nematode) resistance, improved iron deficiency chlorosis, and modified chloride sensitivity; Cotton `` Stoneville (registered trademark) Cotton '' provided with pest resistance (ST5517GLTP, ST4848GLT, ST4949GLT, ST5020GLT, ST5115GLT, ST6182GLT, ST4747GLB2, to respond to the occurrence of weeds and pests in the field in each region. There are nine varieties of ST4946GLB2 and ST6448GLB2).

  Commercially available or developed plants are listed below (A1 to A556). In addition, the contents in parentheses mean [plant name, Event Name, Event code, trade name (Tradename)]. NA means “no information” or “unavailable information”. Many of these plants are registered in the database (GM APPROVAL DATABASE) on the electronic information site (http://www.isaaa.org/) of the INTERNATINAL SERVICE for the ACQUISITION of AGRI-BIOTECH APPLICATIONS, ISAAA. It is listed in.

A1: [Alfalfa, J101, MON-00101-8, Roundup Ready (TM) Alfalfa], A2: [Alfalfa, J101 x J163, MON-00101-8 x MON-00163-7, Roundup Ready (TM) Alfalfa], A3: [Alfalfa, J163, MON-00163-7, Roundup Ready (TM) Alfalfa], A4: [Alfalfa, KK179, MON-00179-5, HarvXtra (TM)], A5: [Alfalfa, KK179 x J101, MON -00179-5 x MON-00101-8], A6: [apple, GD743, OKA-NB001-8, Arctic (TM) "Golden Delicious" Apple], A7: [apple, GS784, OKA-NB002-9, Arctic (Trademark)], A8: [apple, NF872, OKA-NB003-1, Arctic (trademark) Fuji Apple], A9: [Argentina canola, 23-18-17 (Event 18), CGN-89111-8, Laurical ( Trademark) Canola], A10: [Argentine canola, 23-198 (Event 23), CGN-89465-2, Laurical (trademark) Canola], A11: [Argentine canola, 61061, DP-061061-7], A12: [ Argentina Canola, 73496, DP-073496-4, Optimum (Registration Gly canola], A13: [Argentine canola, 73496 x RF3, DP-073496-4 x ACS-BN003-6, NA], A14: [Argentine canola, GT200 (RT200), MON-89249-2, Roundup Ready (Trademark) Canola], A15: [Argentine canola, GT73 (RT73), MON-00073-7, Roundup Ready (trademark) Canola], A16: [Argentine canola, HCN10 (Topas 19/2), NA, Liberty Link ( Trademark) Independence (TM)], A17: [Argentine Canola, HCN28 (T45), ACS-BN008-2, InVigor (TM) Canola], A18: [Argentine Canola, HCN28 x MON88302, ACS-BN008-2 x MON- 88302-9, InVigor ™ x TruFlex ™ Roundup Ready ™ Canola], A19: [Argentina Canola, HCN92 (Topas 19/2), ACS-BN007-1, Liberty Link ™ Innovator ™ ], A20: [Argentina Canola, HCN92 x MON88302, ACS-BN007-1 x MON-88302-9, Liberty Link (TM) Innovator (TM) x TruFlex (TM) Roundup Ready ™ Canola], A21: [Argentine Canola, MON88302, MON-88302-9, TruFlex ™ Roundup Ready ™ Canola], A22: [Argentine Canola, MON88302 x MS8 x RF3, MON-88302- 9 x ACS-BN005-8 x ACS-BN003-6, InVigor ™ x TruFlex ™ Roundup Ready ™ Canola], A23: [Argentina Canola, MON88302 x RF3, MON-88302-9 x ACS-BN003 -6, NA], A24: [Argentine canola, MPS961, NA, Phytaseed (TM) Canola], A25: [Argentine canola, MPS962, NA, Phytaseed (TM) Canola], A26: [Argentine canola, MPS963, NA, Phytaseed (trademark) Canola], A27: [Argentine canola, MPS964, NA, Phytaseed (trademark) Canola], A28: [Argentine canola, MPS965, NA, Phytaseed (trademark) Canola], A29: [Argentine canola, MS1 (B91 -4), ACS-BN004-7, InVigor ™ Canola], A30: [Alze Chin Canola, MS1 x MON88302, ACS-BN004-7 x MON-88302-9, InVigor ™ x TruFlex ™ Roundup Ready ™ Canola], A31: [Argentina Canola, MS1 x RF1 (PGS1), ACS -BN004-7 x ACS-BN001-4, InVigor ™ Canola], A32: [Argentine Canola, MS1 x RF1 (PGS2), ACS-BN004-7 x ACS-BN002-5, InVigor ™ Canola], A33: [Argentine canola, MS1 x RF3, ACS-BN004-7 x ACS-BN003-6, InVigor (trademark) Canola], A34: [Argentina canola, MS8, ACS-BN005-8, InVigor (trademark) Canola], A35: [Argentine canola, MS8 x MON88302, ACS-BN005-8 x MON-88302-9, InVigor (TM) x TruFlex (TM) Roundup Ready (TM) Canola], A36: [Argentine canola, MS8 x RF3, ACS -BN005-8 x ACS-BN003-6, InVigor ™ Canola], A37: [Argentina Canola, MS8 x RF3 x GT73 (RT73), ACS-BN005-8 x ACS-BN003-6 x MON-00073-7 , NA], A38: [Arze Chin Canola, OXY-235, ACS-BN011-5, Navigator ™ Canola], A39: [Argentine Canola, PHY14, NA, NA], A40: [Argentine Canola, PHY23, NA, NA], A41: [Argentina Canola, PHY35, NA, NA], A42: [Argentine canola, PHY36, NA, NA], A43: [Argentine canola, RF1 (B93-101), ACS-BN001-4, InVigor ™ Canola], A44: [Argentine canola, RF1 x MON88302, CS-BN001-4 x MON-88302-9, InVigor ™ x TruFlex ™ Roundup Ready ™ Canola], A45: [Argentine canola, RF2 (B94-2), ACS-BN002-5, InVigor ™ Canola], A46: [Argentine Canola, RF2 x MON88302, ACS-BN002-5 x MON-88302-9, InVigor ™ x TruFlex ™ Roundup Ready ™ Canola ], A47: [Argentine canola, RF3, ACS-BN003-6, InVigor ™ Canola], A48: [Peas, EMBRAPA5.1, EMB-PV051-1, NA], A49: [ Nation, 11 (7442), FLO-07442-4, Moondust (trademark)], A50: [Carnation, 11363 (1363A), FLO-11363-1, Moonshadow (trademark)], A51: [Carnation, 1226A (11226) , FLO-11226-8, Moonshade (TM)], A52: [Carnation, 123.2.2 (40619), FLO-40619-7, Moonshade (TM)], A53: [Carnation, 123.2.38 (40644), FLO -40644-4, Moonlite (TM)], A54: [carnation, 123.8.12, FLO-40689-6, Moonaqua (TM)], A55: [carnation, 123.8.8 (40685), FLO-40685-1, Moonvista (trademark)], A56: [carnation, 1351A (11351), FLO-11351-7, Moonshade (trademark)], A57: [carnation, 1400A (11400), FLO-11400-2, Moonshade (trademark)], A58: [Carnation, 15, FLO-00015-2, Moondust (trademark)], A59: [Carnation, 16, FLO-00016-3, Moondust (trademark)], A60: [Carnation, 19907, IFD-19907-9 , Moonique (TM)], A61: [Carnesi , 25947, IFD-25947-1, Moonpearl (TM)], A62: [Carnation, 25958, IFD-25958-3, Moonberry (TM)], A63: [Carnation, 26407, IFD-26407-2, Moonvelvet (Trademark)], A64: [carnation, 4, FLO-00004-9, Moondust (trademark)], A65: [carnation, 66, FLO-00066-8, NA] A66: [carnation, 959A (11959), FLO -11959-3, Moonshade (TM)], A67: [Carnation, 988A (11988), FLO-11988-7, Moonshade (TM)], A68: [Chicory, RM3-3, NA, SeedLink (TM)], A69: [Chicory, RM3-4, NA, SeedLink (trademark)], A70: [Chicory, RM3-6, NA, SeedLink (trademark)], A71: [Water, 19-51a, DD-01951A-7, NA ], A72: [cotton, 281-24-236, DAS-24236-5, NA], A73: [cotton, 281-24-236 x 3006-210-23 (MX B-13), DAS-24236-5 x DAS-21023-5, WideStrike (TM) Cotton], A74: [cotton, 281-24-236 x 3006-210-23 x COT102 x 81910, DAS-24236-5 x DAS-21023-5 x SYN-IR102 -7 x DAS-81910-7, NA], A75 [Cotton, 3006-210-23, DAS-21023-5, NA], A76: [cotton, 3006-210-23 x 281-24-236 x MON1445, DAS-21023-5 x DAS-24236-5 x MON -01445-2, WideStrike ™ RoundupReady ™ Cotton], A77: [cotton, 3006-210-23 x 281-24-236 x MON88913, DAS-21023-5 x DAS-24236-5 x NAMON-88913 -8, Widestrike ™ RoundupReadyFlex ™ Cotton], A78: [cotton, 3006-210-23 x 281-24-236 x MON88913 x COT102, DAS-21023-5 x DAS-24236-5 x MON-88913 -8 x SYN-IR102-7, Widestrike (TM) RoundupReadyFlex (TM) Cotton], A79: [Water, 31707, NA, BXN (TM) PlusBollgard (TM) Cotton], A80: [Water, 31803, NA, BXN] (Trademark) PlusBollgard (TM) Cotton], A81: [cotton, 31807 x 31808, NA, NA], A82: [cotton, 31807, NA, BXN (TM) PlusBollgard (TM) Cotton], A83: [cotton, 31808 , NA, BXN (TM) PlusBollgard (TM) Cotton], A84: [Water, 42317, NA, BXN (TM) PlusBollgard (TM) Cotton], A85: [Water, 81910, DAS-81910-7, NA], A86: [Catalog, BNLA-6 01, NA, NA], A87: [cotton, BXN10211 (10211), BXN-10211-9, NA], A88: [cotton, BXN10215 (10215), BXN-10215-4NA, BXN (TM) Cotton], A89 : [Cotton, BXN102 cotton 22 (10222), BXN-10222-2, BXN (registered trademark) Cotton], A90: [cotton, BXN10224 (10224), BXN-10224-4NA, BXN (registered trademark) Cotton], A91: [ Cotton, COT102 (IR102), SYN-IR102-7, VIPCOT ™ Cotton], A92: [cotton, COT102 x COT67B, SYN-IR102-7NA x NASYN-IR67B-1, VIPCOT ™ Cotton], A93: [Water, COT102 x COT67B x MON88913, SYN-IR102-7NA x NASYN-IR67B-1NA x NAMON-88913-8, VIPCOT (TM) RoundupReadyFle x (TM) Cotton], A94: [Water, COT102 x MON15985, SYN- IR102-7NA x NAMON-15985-7, Bollgard (R) III], A95: [cotton, COT102 x MON15985 x MON88913, SYN-IR102-7NA x NAMON-15985-7NA x NAMON-88913-8, Bollgard (registered (Trademark) III x RoundupReady (trademark) Flex (trademark)], A96: [cotton, COT102 x MON15985 x MON88913 x MON88701, SYN-IR102-7NA x NAMON-15985-7NA x NAMON-88913-8NA x NAMONNA88701-3 NA], A97: [cotton, COT67B (IR67B), SYN-IR67B-1, NA], A98: [cotton, Event1, NA, JK1], A99: [cotton, GFMCry1A, GTL-GFM311-7, NA], A100: [cotton, GHB119, BCS-GH005-8, NA], A101: [cotton, GHB614, BCS-GH002-5, GlyTol (trademark)], A102: [cotton, GHB614 x LLCotton25, BCS-GH002-5NA x NAACS-GH001-3, GlyTol ™ LibertyLink ™, A103: [cotton, GHB614 x LLCotton25 x MON15985, BCS-GH002-5NA x NAACS-GH001-3NA x NAMON-15985-7, NA], A104: [Cotton, GHB614 x MON15985, BCS-GH002-5NA x NAMON-15985, NA], A105: [cotton, GHB614 x T304-40 x GHB119, BCS-GH002-5NA x NABCS-GH004-7NA x NABCS-GH005-8 , Glytol (trademark) x Twinlink (trademark)], A106: [Water, GHB614 x T304-40 x GHB119 x COT102, BCS-GH002-5NA x NABCS-GH004-7NA x NABCS-GH005-8NA x NASYN-IR102-7 , Glytol ™ x Twinlink ™ x VIPCOT ™ Cotton], A107: [cotton, GK12, NA, NA], A108: [cotton, LLCotton25, ACS-GH001-3NA, Fiberma x ™ LibertyLink ( Trademark)], A109: [ , LLCotton25 x MON15985, ACS-GH001-3NA x NAMON-15985-7, Fibermax x LibertyLink (TM) BollgardII (TM)], A110: [cotton, MLS9124, NA, NA], A111: [cotton, MON1076, MON-89924-2, Bollgard (TM) Cotton], A112: [Water, MON1445, MON-01445-2, RoundupReady (TM) Cotton], A113: [Water, MON15985, MON-15985-7, BollgardII ( Trademark) Cotton], A114: [cotton, MON15985 x MON1445, MON-15985-7NA x NAMON-01445-2, RoundupReady (trademark) BollgardII (trademark) Cotton], A115: [cotton, MON1698, MON-89383-1, RoundupReady (TM) Cotton], A116: [Water, MON531, MON-00531-6, Bollgard (TM) Cotton, Ingard (TM)], A117: [Water, MON531 x MON1445, MON-0531-6NA x NAMON-01445 -2, RoundupReady ™ Bollgard ™ Cotton], A118: [Water, MON757, MON-00757-7, Bollgard ™ Cotton], A119: [Water, MON88701, MONNA88701-3, NA], A120: [Cotton, MON88701 x MON88913, MONNA88701-3NA x NAMON-88913-8, NA], A121: [cotton, MON88701 x MON88913 x MON15985, MONNA88701-3NA x NAMON-88913-8NA x NAMON-15985-7, Bollgard II (R) XtendFlex (TM) Cotton, A122: [Water, MON88913, MON-88913-8, RoundupReady (TM)] Flex ™ Cotton], A123: [cotton, MON88913 x MON15985, MON-88913-8NA x NAMON-15985-7, RoundupReady ™ Flex ™ BollgardII ™ Cotton], A124: [cotton, NgweChi6Bt, NA, NgweChi6Bt], A125: [cotton, SGK321, NA, NA], A126: [cotton, T303-3, BCS-GH003-6, NA], A127: [cotton, T304-40, BCS-GH004-7, NA], A128: [cotton, T304-40 x GHB119, BCS-GH004-7NA x NABCS-GH005-8, TwinLink (TM) Cotton], A129: [creeping bent glass, ASR368, SMG-36800-2, NA] , A130: [Eggplant, BtBrinjalEventEE1, BtBrinjalEventEE1, BARIBtBegun-1, -2, -3and-4], A131: [Eucalyptus, H421, H421, GMEucalyptus], A132: [Ama, FP967 (CDCTriffid), CDC-FL001-2 , CDCTriffidFla x], A133: [Lentil, RH44, RH44, Clearfield (registered trademark)]
lentil], A134: [corn, 32138, DP-32138-132138, 2138SPTmaintainer], A135: [corn, 3272, SYN-E3272-5, Enogen (TM)], A136: [corn, 3272 x Bt11, SYN-E3272 -5 x SYN-BT011-1, NA], A137: [Corn, 3272 x Bt11 x GA21, SYN-E3272-5 x SYN-BT011-1 x MON-00021-9, NA], A138: [Corn, 3272 x Bt11 x MIR604, SYN-E3272-5 x SYN-BT011-1 x SYN-IR604-5, NA], A139: [Maize, 3272 x BT11 x MIR604 x GA21, SYN-E3272-5 x SYN-BT011-1 x SYN-IR604-5 x MON-00021-9, NA], A140: [Maize, 3272 x Bt11 x MIR604 x TC1507 x 5307 x GA21, SYN-E3272-5 x SYN-BT011-1 x SYN-IR604-5 x DAS-01507-1 x SYN-05307-1 x MON-00021-9, NA], A141: [Maize, 3272 x GA21, SYN-E3272-5 x MON-00021-9, NA], A142: [Maize , 3272 x MIR604, SYN-E3272-5 x SYN-IR604-5, NA], A143: [Maize, 3272 x MIR604 x GA21, SYN-E3272-5 x SYN-IR604-5 x MON-00021-9, NA ], A144: Corn 33121, DP-033121-3, NA], A145: [Maize, 4114, DP-004114-3, NA], A146: [Maize, 5307, SYN-05307-1, Agrisure (registered trademark) Duracade (trademark)] , A147: [Maize, 5307 x GA21, SYN-05307-1 x MON-00021-9, NA], A148: [Maize, 5307 x MIR604 x Bt11 x TC1507 x GA21, SYN-05307-1 x SYN-IR604- 5 x SYN-BT011-1 x DAS-01507-1 x MON-00021-9, Agrisure (R) Duracade (TM) 5122], A149: [Maize, 5307 x MIR604 x Bt11 x TC1507 x GA21 x MIR162, SYN -05307-1 x SYN-IR604-5 x SYN-BT011-1 x DAS-01507-1 x MON-00021-9 x SYN-IR162-4, Agrisure (R) Duracade (TM) 5222], A150: [ Maize, 59122, DAS-59122-7, Hercule x (registered trademark) RW], A151: [Maize, 59122 x DAS40278, DAS-59122-7 x DAS-40278-9, NA], A152: [Maize, 59122 x GA21 , DAS-59122-7 x MON-00021-9, NA], A153: [Maize, 59122 x MIR604, DAS-59122-7 x SYN-IR604-5, NA], A154: [Maize , 59122 x MIR604 x GA21, DAS-59122-7 x SYN-IR604-5 x MON-00021-9, NA], A155: [Maize, 59122 x MIR604 x TC1507, DAS-59122-7 x SYN-IR604-5 x DAS-01507-1, NA], A156: [corn, 59122 x MIR604 x TC1507 x GA21, DAS-59122-7 x SYN-IR604-5 x DAS-01507-1 x MON-00021-9, NA], A157: [Maize, 59122 x MON810, DAS-59122-7 x MON-00810-6, NA], A158: [Maize, 59122 x MON810 x MIR604, DAS-59122-7 x MON-00810-6 x SYN-IR604 -5, NA], A159: [Maize, 59122 x MON810 x NK603, DAS-59122-7 x MON-00810-6 x MON-00603-6, NA], A160: [Maize, 59122 x MON810 x NK603 x MIR604 , DAS-59122-7 x MON-00810-6 x MON-00603-6 x SYN-IR604-5, NA], A161: [Maize, 59122 x MON88017, DAS-59122-7 x MON-88017-3, NA ], A162: [Maize, 59122 x MON88017 x DAS40278, DAS-59122-7 x MON-88017-3 x DAS-40278-9, NA], A163: [Maize, 59122 x NK603, DAS-59122-7 x MON -00603-6, Herculex ™ RWRoundu pReady ™ 2], A164: [corn, 59122 x NK603 x MIR604, DAS-59122-7 x MON-00603-6 x SYN-IR604-5, NA], A165: [corn, 59122 x TC1507 x GA21, DAS-59122-7 x DAS-01507-1 x MON-00021-9, NA], A166: [Maize, 676, PH-000676-7, NA], A167: [Maize, 678, PH-000678-9, NA], A168: [Maize, 680, PH-000680-2, NA], A169: [Maize, 98140, DP-098140-6, Optimum GAT (trademark)], A170: [Maize, 98140 x 59122, DP- 098140-6 x DAS-59122-7, NA], A171: [Maize, 98140 x TC1507, DP-098140-6 x DAS-01507-1, NA], A172: [Maize, 98140 x TC1507 x 59122, DP- 098140-6 x DAS-01507-1 x DAS-59122-7, NA], A173: [Maize, Bt10, NA, Bt10], A174: [Maize, Bt11 (X4334CBR, X4734CBR), SYN-BT011-1 , Agrisure (trademark) CB / LL], A175: [Maize, Bt11 x 5307, SYN-BT011-1 x SYN-05307-1, NA], A176: [Maize, Bt11 x 5307 x GA21 SYN-BT011-1 x SYN-05307-1 x MON-00021-9, NA], A177: [Maize, Bt11 x 59122, SYN-BT011-1 x DAS-59122-7, NA], A178: [Maize, Bt11 x 59122 x GA21, SYN-BT011-1 x DAS-59122-7 x MON-00021-9, NA], A179: [Maize, Bt11 x 59122 x MIR604, SYN-BT011-1 x DAS-59122-7 x SYN-IR604-5, NA], A180: [Maize, Bt11 x 59122 x MIR604 x GA21, SYN-BT011-1 x DAS-59122-7 x SYN-IR604-5 x MON-00021-9, NA], A181 : [Maize, Bt11 x 59122 x MIR604 x TC1507, SYN-BT011-1 x DAS-59122-7 x SYN-IR604-5 x DAS-01507-1, NA], A182: [Maize, BT11 x 59122 x MIR604 x TC1507 x GA21, SYN-BT011-1 x DAS-59122-7 x SYN-IR604-5 x DAS-01507-1 x MON-00021-9, Agrisure (R) 3122], A183: [Maize, Bt11 x 59122 x TC1507, SYN-BT011-1 x DAS-59122-7 x DAS-01507-1, NA], A184: [Maize, Bt11 x 59122 x TC1507 x GA21, SYN-BT011-1 x DAS-59122-7 x DAS -01507-1 x MON-00021-9, NA], A185: [Maize, Bt1 1 x GA21, SYN-BT011-1 x MON-00021-9, Agrisure (TM) GT / CB / LL], A186: [Maize, Bt11 x MIR162, SYN-BT011-1 x SYN-IR162-4, Agrisure ( (Registered trademark) Viptera (trademark) 2100], A187: [Maize, Bt11 x MIR162 x 5307, SYN-BT011-1 x SYN-IR162-4 x SYN-05307-1, NA], A188: [Maize, Bt11 x MIR162 x5307 x GA21, SYN-BT011-1 x SYN-IR162-4 x SYN-05307-1 x MON-00021-9, NA], A189: [Maize, Bt11 x MIR162 x GA21, SYN-BT011-1 x SYN -IR162-4 x MON-00021-9, Agrisure (registered trademark) Viptera (trademark) 3110], A190: [corn, BT11 x MIR162 x MIR604, SYN-BT011-1 x SYN-IR162-4 x SYN-IR604- 5, Agrisure® Viptera® 3100], A191: [corn, BT11 x MIR162 x MIR604 x 5307, SYN-BT011-1 x SYN-IR162-4 x SYN-IR604-5 x SYN-05307-1 , NA], A192: [Maize, Bt11 x MIR162 x MIR604 x 5307 x GA21, SYN-BT011-1 x SYN-IR162-4 x SYN-IR604-5 x SYN-05307-1 x MON-00021-9, NA ], A193: [Maize, Bt11 x MIR162 x MIR604 x GA21, SYN-BT011-1 x SYN-IR162-4 x SYN-IR604-5 x MON-00021-9, Agrisure (R) Viptera (R) 3111, Agrisure (R) Viptera (R) ) 4], A194: [Maize, Bt11 x MIR162 x MIR604 x MON89034 x 5307 x GA21, SYN-BT011-1 x SYN-IR162-4 x SYN-IR604-5 x MON-89034-3 x SYN-05307-1 x MON-00021-9, NA], A195: [corn, BT11 x MIR162 x MIR604 x TC1507, SYN-BT011-1 x SYN-IR162-4 x SYN-IR604-5 x DAS-01507-1, NA], A196: [Maize, BT11 x MIR162 x MIR604 x TC1507 x 5307, SYN-BT011-1 x SYN-IR162-4 x SYN-IR604-5 x DAS-01507-1 x SYN-05307-1, NA], A197: [Maize, Bt11 x MIR162 x MIR604 x TC1507 x GA21, SYN-BT011-1 x SYN-IR162-4 x SYN-IR604-5 x DAS-01507-1 x MON-00021-9, NA], A198: [Maize , Bt11 x MIR162 x MON89034, SYN-BT011-1 x SYN-IR162-4 x MON-89034-3, NA], A199: [Maize, Bt11 x MIR162 x MON89034 x GA21, SYN-BT011-1 x SYN-IR162 -4 x MON-89034-3 x MON-00021-9, NA], A200: [ Maize, Bt11 x MIR162 x TC1507, SYN-BT011-1 x SYN-IR162-4 x DAS-01507-1, NA], A201: [Maize, Bt11 x MIR162 x TC1507 x 5307, SYN-BT011-1 x SYN- IR162-4 x DAS-01507-1 x SYN-05307-1, NA], A202: [Maize, Bt11 x MIR162 x TC1507 x 5307 x GA21, SYN-BT011-1 x SYN-IR162-4 x DAS-01507- 1 x SYN-05307-1 x MON-00021-9, NA], A203: [Maize, Bt11 x MIR162 x TC1507 x GA21, SYN-BT011-1 x SYN-IR162-4 x DAS-01507-1 x MON- 00021-9, Agrisure (TM) Viptera3220], A204: [Maize, Bt11 x MIR604, SYN-BT011-1 x SYN-IR604-5, Agrisure (TM) CB / LL / RW], A205: [Maize, Bt11x MIR604 x 5307, SYN-BT011-1 x SYN-IR604-5 x SYN-05307-1, NA], A206: [Maize, Bt11 x MIR604 x 5307 x GA21, SYN-BT011-1 x SYN-IR604-5 x SYN-05307-1 x MON-00021-9, NA], A207: [Maize, BT11 x MIR604 x GA21, SYN-BT011-1 x SYN-IR604-5 x MON-00021-9, Agrisure (TM) 3000GT] , A208: [Maize, Bt11 x MIR604 x TC1507, SYN-BT011-1 x SYN-IR604-5 x DAS-01507-1, NA], A209: [Maize, Bt11 x MIR604 x TC1507 x 5307, SYN-BT011-1 x SYN-IR604-5 x DAS- 01507-1 x SYN-05307-1, NA], A210: [Maize, Bt11 x MIR604 x TC1507 x GA21, SYN-BT011-1 x SYN-IR604-5 x DAS-01507-1 x MON-00021-9, NA], A211: [Maize, Bt11 x MON89034, SYN-BT011-1 x MON-89034-3, NA], A212: [Maize, Bt11 x MON89034 x GA21, SYN-BT011-1 x MON-89034-3 x MON-00021-9, NA], A213: [Maize, Bt11 x TC1507, SYN-BT011-1 x DAS-01507-1, NA], A214: [Maize, Bt11 x TC1507 x 5307, SYN-BT011-1 x DAS-01507-1 x SYN-05307-1, NA], A215: [Maize, Bt11 x TC1507 x 5307 x GA21, SYN-BT011-1 x DAS-01507-1 x SYN-05307-1 x MON-00021- 9, NA], A216: [Maize, Bt11 x TC1507 x GA21, SYN-BT011-1 x DAS-01507-1 x MON-00021-9, NA], A217: [Maize, Bt176 (176), SYN-EV176 -9, NaturGardKnockOut (TM), Max imizer (TM)], A218 : [Maize, BVLA430101, NA, NA], A219: [Maize, CBH-351, ACS-ZM004-3, Starlink (TM) Maize], A220: [Maize, DAS40278, DAS-40278-9, Enlist (TM) Maize], A221: [Maize, DAS40278 x NK603, DAS-40278-9 x MON-00603-6, NA], A222: [Maize, DBT418, DKB-89614-9, Bt Xtra ™ Maize], A223 : [Maize, DLL25 (B16), DKB-89790-5, NA], A224: [Maize, GA21, MON-00021-9, RoundupReady (TM) Maize, Agrisure (TM) GT], A225: [Maize, GA21 x MON810, MON-00021-9 x MON-00810-6, RoundupReady (TM) YieldGard (TM) maize], A226: [Maize, GA21 x T25, MON-00021-9 x ACS-ZM003-2, NA], A227: [Maize, HCEM485, HCEM485, NA], A228: [Maize, LY038, REN-00038-3, Mavera (TM) Maize], A229: [Maize, LY038 x MON810, REN-00038-3 x MON-00810 -6, Mavera ™ YieldGard ™ Maize], A230: Koshi, MIR162, SYN-IR162-4, Agrisure ™ Viptera], A231: [Maize, MIR162 x 5307, SYN-IR162-4 x SYN-05307-1, NA], A232: [Maize, MIR162 x 5307 x GA21, SYN-IR162-4 x SYN-05307-1 x MON-00021-9, NA], A233: [Maize, MIR162 x GA21, SYN-IR162-4 x MON-00021-9, NA], A234: [ Maize, MIR162 x MIR604, SYN-IR162-4 x SYN-IR604-5, NA], A235: [Maize, MIR162 x MIR604 x 5307, SYN-IR162-4 x SYN-IR604-5 x SYN-05307-1, NA], A236: [Maize, MIR162 x MIR604 x 5307 x GA21, SYN-IR162-4 x SYN-IR604-5 x SYN-05307-1 x MON-00021-9, NA], A237: [Maize, MIR162 x MIR604 x GA21, SYN-IR162-4 x SYN-IR604-5 x MON-00021-9, NA], A238: [Maize, MIR162 x MIR604 x TC1507 x 5307, SYN-IR162-4 x SYN-IR604-5 x DAS-01507-1 x SYN-05307-1, NA], A239: [Maize, MIR162 x MIR604 x TC1507 x 5307 x GA21, SYN-IR162-4 x SYN-IR604-5 x DAS-01507-1 x SYN- 05307-1 x MON-00021-9, NA], A 240: [Maize, MIR162 x MIR604 x TC1507 x GA21, SYN-IR162-4 x SYN-IR604-5 x DAS-01507-1 x MON-00021-9, NA], A241: [Maize, MIR162 x MON89034, SYN -IR162-4 x MON-89034-3, NA], A242: [Corn, MIR162 x MON89034 x GA21, SYN-IR162-4 x MON-89034-3 x MON-00021-9, NA], A243: [Corn , MIR162 x NK603, SYN-IR162-4 x MON-00603-6, NA], A244: [Maize, MIR162 x TC1507, SYN-IR162-4 x DAS-01507-1, NA], A245: [Maize, MIR162 x TC1507 x 5307, SYN-IR162-4 x DAS-01507-1 x SYN-05307-1, NA], A246: [Maize, MIR162 x TC1507 x
5307 x GA21, SYN-IR162-4 x DAS-01507-1 x SYN-05307-1 x MON-00021-9, NA], A247: [Maize, MIR162 x TC1507 x GA21, SYN-IR162-4 x DAS- 01507-1 x MON-00021-9, NA], A248: [Maize, MIR604, SYN-IR604-5, Agrisure (TM) RW], A249: [Maize, MIR604 x 5307, SYN-IR604-5 x SYN- 05307-1, NA], A250: [Maize, MIR604 x 5307 x GA21, SYN-IR604-5 x SYN-05307-1 x MON-00021-9, NA], A251: [Maize, MIR604 x GA21, SYN- IR604-5 x MON-00021-9, Agrisure (TM) GT / RW], A252: [Maize, MIR604 x NK603, SYN-IR604-5 x MON-00603-6, NA], A253: [Maize, MIR604 x TC1507, SYN-IR604-5 x DAS-01507-1, Optimum (registered trademark) TRIsect (trademark)], A254: [Maize, MIR604 x TC1507 x 5307, SYN-IR604-5 x DAS-01507-1 x SYN- 05307-1, NA], A255: [Maize, MIR604 x TC1507 x 5307 x GA21, SYN-IR604-5 x TC1507 x SYN-05307-1 x MON-00021-9, NA], A256: [Maize, MIR604 x TC1507 x GA21 SYN-IR604-5 x TC1507 x MON-00021-9, NA], A257: [Maize, MON801 (MON80100), MON801, NA], A258: [Maize, MON802, MON-80200-7, NA], A259: [Maize, MON809, PH-MON-809-2, NA], A260: [Maize, MON810, MON-00810-6, YieldGard (trademark), MaizeGard (trademark)], A261: [Maize, MON810 x MIR162, MON -00810-6 x SYN-IR162-4, NA], A262: [Corn, MON810 x MIR162 x NK603, MON-00810-6 x SYN-IR162-4 x MON-00603-6, NA], A263: [Corn , MON810 x MIR604, MON-00810-6 x SYN-IR604-5, NA], A264: [Maize, MON810 x MON88017, MON-00810-6 x MON-88017-3, YieldGard (TM) VTTriple], A265: [Maize, MON810 x NK603 x MIR604, MON-00810-6 x MON-00603-6 x SYN-IR604-5, NA], A266: [Maize, MON832, NA, RoundupReady (TM) Maize], A267: [Maize , MON863, MON-00863-5, YieldGard (TM) Rootworm RW, MaxGard (TM)], A268: [Maize , MON863 x MON810, MON-00863-5 x MON-00810-6, YieldGard (TM) Plus], A269: [Maize, MON863 x MON810 x NK603, MON-00603-6 x MON-00810-6 x MON-00863 -5, YieldGard (TM) PluswithRR], A270: [Maize, MON863 x NK603, MON-00863-5 x MON-00603-6, YieldGard (TM) RW + RR], A271: [Maize, MON87403, MON87403-1 , NA], A272: [Maize, MON87411, MON-87411-9, NA], A273: [Maize, MON87419, MON87419-8, NA], A274: [Maize, MON87427, MON-87427-7, RoundupReady (trademark) ) Maize], A275: [Maize, MON87427 x 59122, MON-87427-7 x DAS-59122-7, NA], A276: [Maize, MON87427 x MON88017, MON-87427-7 x MON-88017-3, NA ], A277: [Corn, MON87427 x MON88017 x 59122, MON-87427-7 x MON-88017-3 x DAS-59122-7, NA], A278: [Corn, MON87427 x MON89034, MON-87427-7 x MON -89034-3, NA], A279: [Corn, MON87427 x MON89034 x 59122, MON-87427- 7 x MON-89034-3 x DAS-59122-7, NA], A280: [corn, MON87427 x MON89034 x MON88017, MON-87427-7 x MON-89034-3 x MON-88017-3, NA], A281 : [Maize, MON87427 x MON89034 x MON88017 x 59122, MON-87427-7 x MON-89034-3 x MON-88017-3 x 59122, NA], A282: [Maize, MON87427 x MON89034 x NK603, MON-87427- 7 x MON-89034-3 x MON-00603-6, NA], A283: [Maize, MON87427 x MON89034 x TC1507, MON-87427-7 x MON-89034-3 x DAS-01507-1, NA], A284 : [Maize, MON87427 x MON89034 x TC1507 x 59122, MON-87427-7 x MON-89034-3 x DAS-01507-1 x DAS-59122-7, NA], A285: [Maize, MON87427 x MON89034 x TC1507 x MON87411 x 59122, MON-87427-7 x MON-89034-3 x DAS-01507-1 x MON-87411-9 x DAS-59122-7, NA], A286: [Maize, MON87427 x MON89034 x TC1507 x MON88017, MON-87427-7 x MON-89034-3 x DAS-01507-1 x MON-88017-3, NA], A287: [Corn, MON87427 x MON89034 x MIR162 x NK603, MON-87427-7 x MON-89034- Three x SYN-IR162-4 x MON-00603-6, NA], A288: [Corn, MON87427 x MON89034 x TC1507 x MON88017 x 59122, MON-87427-7 x MON-89034-3 x DAS-01507-1 x MON -88017-3 x DAS-59122-7, NA], A289: [Maize, MON87427 x NK603, MON-87427-7 x MON-00603-6, NA], A290: [Maize, MON87427 x TC1507, MON-87427 -7 x DAS-01507-1, NA], A291: [Corn, MON87427 x TC1507 x 59122, MON-87427-7 x DAS-01507-1 x DAS-59122-7, NA], A292: [Corn, MON87427 x TC1507 x MON88017, MON-87427-7 x DAS-01507-1 x MON-88017-3, NA], A293: [Maize, MON87427 x TC1507 x MON88017 x 59122, MON-87427-7 x DAS-01507-1 x MON-88017-3 x DAS-59122-7, NA], A294: [Maize, MON87460, MON-87460-4, Genuity (R) DroughtGard (TM)], A295: [Maize, MON87460 x MON88017, MON -87460-4 x MON-88017-3, NA], A296: [corn, MON87460 x MON89034 x MON88017, MON-87460-4 x MON-89034-3 x MON-88017-3, NA], A29 7: [Maize, MON87460 x MON89034 x NK603, MON-87460-4 x MON-89034-3 x MON-00603-6, NA], A298: [Maize, MON87460 x NK603, MON-87460-4 x MON-00603 -6, NA], A299: [Maize, MON88017, MON-88017-3, YieldGard ™ VT ™ Rootworm ™ RR2], A300: [Maize, MON88017 x DAS40278, MON-88017-3 x DAS -40278-9, NA], A301: [Maize, MON89034, MON-89034-3, YieldGard (TM) VTPro (TM)], A302: [Maize, MON89034 x 59122, MON-89034-3 x DAS-59122- 7, NA], A303: [Maize, MON89034 x 59122 x DAS40278, MON-89034-3 x DAS-59122-7 x DAS-40278-9, NA], A304: [Maize, MON89034 x 59122 x MON88017, MON- 89034-3 x DAS-59122-7 x MON-88017-3, NA], A305: [corn, MON89034 x 59122 x MON88017 x DAS40278, MON-89034-3 x DAS-59122-7 x MON-88017-3 x DAS-40278-9, NA], A306: [Maize, MON89034 x DAS40278, MON-89034-3 x DAS-40278-9, NA], A307: [Tow Sorghum, MON89034 x MON87460, MON-89034-3 x MON-87460-4, NA], A308: [Maize, MON89034 x MON88017, MON-89034-3 x MON-88017-3, Genuity (R) VTTriplePro (trademark) )], A309: [Maize, MON89034 x MON88017 x DAS40278, MON-89034-3 x MON-88017-3 x DAS-40278-9, NA], A310: [Maize, MON89034 x NK603, MON-89034-3 x MON-00603-6, Genuity (R) VTDoublePro (TM)], A311: [corn, MON89034 x NK603 x DAS40278, MON-89034-3 x MON-00603-6 x DAS-40278-9, NA], A312 : [Corn, MON89034 x TC1507, MON-89034-3 x DAS-01507-1, NA], A313: [Corn, MON89034 x TC1507 x 59122, MON-89034-3 x DAS-01507-1 x DAS-59122- 7, NA], A314: [corn, MON89034 x TC1507 x 59122 x DAS40278, MON-89034-3 x DAS-01507-1 x DAS-59122-7 x DAS-40278-9, NA], A315: [corn, MON89034 x TC1507 x DAS40278, MON-89034-3 x DAS-01507-1 x DAS-40278-9, NA], A316: [Corn, MON890 34 x TC1507 x MON88017, MON-89034-3 x DAS-01507-1 x MON-88017-3, NA], A317: [Maize, MON89034 x TC1507 x MON88017 x 59122, MON-89034-3 x DAS-01507- 1 x MON-88017-3 x DAS-59122-7, Genuity (R) SmartStax (TM)], A318: [Maize, MON89034 x TC1507 x MON88017 x 59122 x DAS40278, MON-89034-3 x DAS-01507 -1 x MON-88017-3 x DAS-59122-7 x DAS-40278-9, NA], A319: [Corn, MON89034 x TC1507 x MON88017 x DAS40278, MON-89034-3 x DAS-01507-1 x MON -88017-3 x DAS-59122-7 x DAS-40278-9, NA], A320: [Maize, MON89034 x TC1507 x NK603, MON-89034-3 x DAS-01507-1 x MON-00603-6, PowerCore (Trademark)], A321: [corn, MON89034 x TC1507 x NK603 x DAS40278, MON-89034-3 x DAS-01507-1 x MON-00603-6 x DAS-40278-9, NA], A322: [corn, MON89034 x TC1507 x NK603 x MIR162, MON-89034-3 x DAS-01507-1 x MON-00603-6 x SYN-IR162-4, NA], A323: (Maize, MON89034 x TC1507 x NK603 x MIR162 x DAS402 78, MON-89034-3 x DAS-01507-1 x MON-00603-6 x SYN-IR162-4 x DAS-40278-9, PowerCore (TM) x MIR162 x Enlist (TM)], A324: [Maize, MON89034 x GA21, MON-89034-3 x MON-00021-9, NA], A325: [Maize, MS3, ACS-ZM001-9, InVigor (TM) Maize], A326: [Maize, MS6, ACS-ZM005- 4, InVigor (TM) Maize], A327: [Maize, MZHG0JG, SYN-000JG-2, NA], A328: [Maize, MZIR098, SYN-00098-3, NA], A329: [Maize, NK603, MON- 00603-6, RoundupReady ™ 2Maize], A330: [Maize, NK603 x MON810 x 4114 x MIR604, MON-00603-6 x MON-00810-6 x DP004114-3 x SYN-IR604-4, NA], A331 : [Maize, NK603 x MON810, MON-00603-6 x MON-00810-6, YieldGard (trademark) CB + RR], A332: [Maize, NK603 x T25, MON-00603-6 x ACS-ZM003-2, RoundupReady (TM) LibertyLink (TM) Maize], A333: [Maize, T14, ACS-ZM002-1, LibertyLink (TM) Maize], A334: [Toma Kosi, T25, ACS-ZM003-2, LibertyLink (TM) Maize], A335: [Maize, T25 x MON810, ACS-ZM003-2 x MON-00810-6, LibertyLink (TM) Yieldgard (TM) Maize], A336 : [Maize, TC1507, DAS-01507-1, Hercule x (trademark) I, Hercule x (trademark) CB], A337: [Maize, TC1507 x 59122 x MON810 x MIR604 x NK603, DAS-01507-1 x DAS- 59122-7 x MON-00810-6 x SYN-IR604-5 x MON-00603-6, Optimum (trademark) Intrasect X treme], A338: [Maize, TC1507 x MON810 x MIR604 x NK603, DAS-01507-1 x MON-00810-6 x SYN-IR604-5 x MON-00603-6, NA], A339: [Maize, TC1507 x 5307, DAS-01507-1 x SYN-05307-1, NA], A340: [Maize, TC1507 x 5307 x GA21, DAS-01507-1 x SYN-05307-1 x MON-00021-9, NA], A341: [Maize, TC1507 x 59122, DAS-01507-1 x DAS-59122-7, Hercule x XTRA (trademark)], A342: [Maize, TC1507 x 59122 x DAS40278, DAS-01507-1 x DAS-59122-7 x DAS-40278-9, NA], A343: [Maize, TC1507 x 59122 x MON810, DAS-01507-1 x DAS-59122-7 x MON-00810-6, Optimum (R) AcreMax (R) Xtra], A344: [Maize, TC1507 x 59122 x MON810 x MIR604, DAS-01507-1 x DAS-59122-7 x MON-00810-6 x SYN-IR604-5, Optimum (R) AcreMa x (R) X Treme], A345: [Maize, TC1507 x 59122 x MON810 x NK603, DAS-01507-1 x DAS-59122-7 x MON-00810-6 x MON-00603-6, Optimum (TM) Intrasect X TRA], A346: [Maize, TC1507 x 59122 x MON88017, DAS-01507- 1 x DAS-59122-7 x MON-88017-3, NA], A347: [Maize, TC1507 x 59122 x MON88017 x DAS40278, DAS-01507-1 x DAS-59122-7 x MON-88017-3 x DAS- 40278-9, NA], A348: [Maize, TC1507 x 59122 x NK603, DAS-01507-1 x DAS-59122-7 x MON-00603-6, Hercule x X TRA (trademark) RR], A349: [Maize , TC1507 x 59122 x NK603 x MIR604, DAS-01507-1 x DAS-59122-7 x MON-00603-6 x SYN-IR604-5, NA], A350: [Maize, TC1507 x DAS40278, DAS-01507-1 x DAS-4 0278-9, NA], A351: [Maize, TC1507 x GA21, DAS-01507-1 x MON-00021-9, NA], A352: [Maize, TC1507 x MIR162 x NK603, DAS-01507-1 x SYN- IR162-4 x MON-00603-6, Optimum (R) Leptra (TM)], A353: [Maize, TC1507 x MIR604 x NK603, DAS-01507-1 x SYN-IR604-5 x MON-00603-6, Optimum® TRIsect], A354: [Maize, TC1507 x MON810, DAS-01507-1 x MON-00, NA], A355: [Maize, TC1507 x MON810 x MIR162, DAS-01507-1 x MON-00810- 6 x SYN-IR162-4, NA], A356: [Maize, TC1507 x MON810 x MIR162 x NK603, DAS-01507-1 x MON-
00810-6 x SYN-IR162-4 x MON-00603-6, NA], A357: [Maize, TC1507 x MON810 x MIR604, DAS-01507-1 x MON-00810-6 x SYN-IR604-5, NA] , A358: [Maize, TC1507 x MON810 x NK603, DAS-01507-1 x MON-00810-6 x MON-00603-6, Optimum (trademark) Intrasect], A359: [Maize, TC1507 x MON810 x NK603 x MIR604, DAS-01507-1 x MON-00810-6 x MON-00603-6 x SYN-IR604-5, NA], A360: [Maize, TC1507 x MON88017, DAS-01507-1 x MON-88017-3, NA] , A361: [Maize, TC1507 x MON88017 x DAS40278, DAS-01507-1 x MON-88017-3 x DAS-40278-9, NA], A362: [Maize, TC1507 x NK603, DAS-01507-1 x MON- 00603-6, Hercule x (trademark) IRR], A363: [Maize, TC1507 x NK603 x DAS40278, DAS-01507-1 x MON-00603-6 x DAS-40278-9, NA], A364: [Maize, TC6275 , DAS-06275-8, NA], A365: [Maize, VCO-01981-5, VCO-01981-5, NA], A366: [Maize, DK404SR, DK404SR, NA], A367: [Maize , EXP1910IT, EXP1910IT, NA], A368: [Melon, MelonA, NA, NA], A369: [Melon, MelonB, NA, NA], A370: [Papaya, 55-1, CUH-CP551-8, Rainbow, SunUp ], A371: [Papaya, 63-1, CUH-CP631-7, NA], A372: [Papaya, Huanong No.1, NA, Huanong No.1], A373: [Papaya, X17-2, UFL-X17CP-6 , NA], A374: [Petunia, Petunia-CHS, NA, NA], A375: [Plum, C-5, ARS-PLMC5-6, NA], A376: [Polish canola, HCR-1, NA, NA] , A377: [Polish canola, ZSR500, NA, Hysyn101RRRoundup-Ready (trademark)], A378: [Polish canola, ZSR502, NA, Hysyn101RRRoundup-Ready (trademark)], A379: [Polish canola, ZSR503, NA, Hysyn101RRRoundup-Ready] (Trademark)], A380: [poplar, Btpoplar, poplar12 (Populusnigra), NA, NA], A381: [poplar, Hybridpoplarclone741, NA, NA], A382: [potato, 1210amk, NA, Lugovskoiplus], A383: [potato , 2904 / 1kgs, NA, Elizavetaplus], A384: [ Potato, AM04-1020, BPS-A1020-5, StarchPotato], A385: [Potato, ATBT04-27, NMK-89367-8, AtlanticNewLeaf (TM) potato], A386: [Potato, ATBT04-30, NMK-89613- 2, AtlanticNewLeaf (TM) potato], A387: [Potato, ATBT04-31, NMK-89170-9, AtlanticNewLeaf (TM) potato], A388: [Potato, ATBT04-36, NMK-89279-1, AtlanticNewLeaf (TM) potato], A389: [Potato, ATBT04-6, NMK-89761-6, AtlanticNewLeaf ™ potato], A390: [Potato, BT06, NMK-89812-3, NewLeaf ™ RussetBurbankpotato], A391: [Potato, BT10, NMK-89175-5, NewLeaf ™ RussetBurbankpotato], A392: [Potato, BT12, NMK-89601-8, NewLeaf ™ RussetBurbankpotato], A393: [Potato, BT16, NMK-89167-6, NewLeaf ( Trademark) RussetBurbankpotato], A394: [Potato, BT17, NMK-89593-9, NewLeaf (TM) RussetBurbankpotato], A395: [Potato, BT18, NMK-89906-7, NewLeaf (TM) RussetBur bankpotato], A396: [Potato, BT23, NMK-89675-1, NewLeaf (R) RussetBurbankpotato], A397: [Potato, E12, SPS-00E12-8, Innate (R) Cultivate], A398: [Potato, E24 , SPS-00E24-2, NA], A399: [Potato, EH92-527-1, BPS-25271EH92-527-1-9, Amflora ™], A400: [Potato, F10, SPS-00F10-7, Innate (registered trademark) Generate, A401: [Potato, F37, SPS-00F37-7, NA], A402: [Potato, G11, SPS-00G11-9, NA], A403: [Potato, H37, SPS-00H37] -9, NA], A404: [Potato, H50, SPS-00H50-4, NA], A405: [Potato, HLMT15-15, NA, Hi-LiteNewLeaf (TM) Ypotato], A406: [Potato, HLMT15-3] , NA, Hi-LiteNewLeaf (TM) Ypotato], A407: [Potato, HLMT15-46, NA, Hi-LiteNewLeaf (TM) Ypotato], A408: [Potato, J3, SPS-000J3-4, Innate (R)] Accelerate], A409: [Potato, J55, SPS-00J55-2, NA], A410: [Potato, J7 8, SPS-00J78-7, NA], A411: [Potato, RBMT15-101, NMK-89653-6, NewLeaf (TM) YRussetBurbankpotato], A412: [Potato, RBMT21-129, NMK-89684-1, NewLeaf ( Trademark) PlusRussetBurbankpotato], A413: [Potato, RBMT21-152, NA, NewLeaf (TM) PlusRussetBurbankpotato], A414: [Potato, RBMT21-350, NMK-89185-6, NewLeaf (TM) PlusRussetBurbankpotato], A415: [Potato, RBMT22-082, NMK-89896-6, NewLeaf ™ PlusRussetBurbankpotato], A416: [Potato, RBMT22-186, NA, NewLeaf ™ PlusRussetBurbankpotato], A417: [Potato, RBMT22-238, NA, NewLeaf ™ PlusRussetBurbankpotato], A418: [Potato, RBMT22-262, NA, NewLeaf (TM) PlusRussetBurbankpotato], A419: [Potato, SEMT15-02, NMK-89935-9, ShepodyNewLeaf (TM) Ypotato], A420: [Potato, SEMT15- 07, NA, ShepodyNewLeaf (TM) Ypotato], A421: [Potato, SEMT15-15, NMK-89930-4, ShepodyNewLeaf (TM) Ypotato], A422: [Potato, SPBT02-5, NMK-89576-1, SuperiorNewLeaf (trademark) potato], A423: [Potato, SPBT02-7, NMK-89724-5, SuperiorNewLeaf (trademark) potato], A424: [ Potato, TIC-AR233-5, TIC-AR233-5, NA], A425: [Potato, V11, SPS-00V11-6, Innate (registered trademark) Invigorate], A426: [Potato, W8, SPS-000W8-4 , Innate (registered trademark) Glaciate], A427: [Potato, X17, SPS-00 X17-5, Innate (registered trademark) Acclimate], A428: [Potato, Y9, SPS-000Y9-7, Innate (registered trademark) ) Hibernate], A429: [rice, 7Crp # 10, NA, NA], A430: [rice, GMShanyou63, NA, BTShanyou63], A431: [rice, Huahui-1 / TT51-1, NA, Huahui-1], A432: [Rice, LLRICE06, ACS-OS001-4, LibertyLink (trademark) rice], A433: [Rice, LLRICE601, BCS-OS003-7, LibertyLink (trademark) rice], A434: [Rice, LLRICE62, ACS-OS002 -5, LibertyLink (TM) rice], A435: [rice, Taromommolaii + cry1Ab, NA, NA], A436: [rice, CL121 x CL141xCFX51, CL121xCL141xCFX51, Clearfield (R) Rice], A437: [Rice, IMINTA-1 x IMINTA-4, IMINTA-1 x IMINTA-4, Clearfield (R) Rice] , A438: [Rice, PWC16, PWC16, NA], A439: [Rose, WKS82 / 130-4-1, IFD-52401-4, NA], A440: [Rose, WKS92 / 130-9-1, IFD- 52901-9, NA], A441: [Soy, 260-05 (G94-1, G94-19, G168), DD-026005-3, NA], A442: [Soy, A2704-12, ACS-GM005-3 , LibertyLink (trademark) soybean], A443: [Soybean, A2704-21, ACS-GM004-2, LibertyLink (trademark) soybean], A444: [Soybean, A5547-127, ACS-GM006-4, LibertyLink (trademark) soybean ], A445: [soy, A5547-35, ACS-GM008-6, LibertyLink (trademark) soybean], A446: [soy, CV127, BPS-CV127-9, Cultivance], A447: [soy, DAS44406-6, DAS] -44406-6, NA], A448: [Soy, DAS68416-4, DAS-68416-4, Enlist (TM) Soybean], A449: [Soy, DAS68416-4 x MON89788, DAS-68416-4 x MON-89788 -1, NA], A450: [Soy, DAS81419, DAS-814 19-2, NA], A451: [Soy, DAS81419 x DAS44406-6, DAS-81419-2 x DAS-44406-6, NA], A452: [Soy, DP305423, DP-305423-1, Treus ™ Or Plenish (trademark)], A453: [soy, DP305423 x GTS40-3-2, DP-305423-1 x MON-04032-6, NA], A454: [soy, DP356043, DP-356043-5, OptimumGAT (Trademark)], A455: [soy, FG72 (FG072-2, FG072-3), MST-FG072-3, NA], A456: [soy, FG72 x A5547-127, MST-FG072-3 x ACS-GM006 -4, Liberty Link (registered trademark) GT27 (trademark)], A457: [Soybean, GTS40-3-2 (40-3-2), MON-04032-6, RoundupReady (trademark) soybean], A458: [Soybean GU262, ACS-GM003-1, LibertyLink ™ soybean], A459: [soybean, IND-00410-5, IND-00410-5, VerdecaHB4Soybean], A460: [soybean, MON87701, MON-87701-2, NA ], A461: [Soy, MON87701 x MON89788, MON-87701-2 x MON-89788-1, Intacta (TM) RoundupReady (TM) 2Pro], A462: [Soy, MON87705, MON-87705-6, VistiveGold (trademark) )], A463: [Soybean, MON87705 x MON87708, MON-87705-6 x MON-87708-9, NA], A464: [Soybean, MON87705 x MON87708 x MON89788, MON-87705-6 x MON-87708-9 x MON-89788-1, NA], A465 : Soybean, MON87705 x MON89788, MON-87705-6 x MON-89788-1, NA], A466: [soybean, MON87708, MON-87708-9, Genuity (R) RoundupReady (TM) 2 X tend (TM) ], A467: [Soy, MON87708 x MON89788, MON-87708-9 x MON-89788-1, Roundup Ready 2 X tend (R)], A468: [Soy, MON87712, MON-87712-4, NA], A469: [Soy, MON87751, MON-87751-7, NA], A470: [Soy, MON87751 x MON87701 x MON87708 x MON89788, MON-87751-7 x MON-87701-2 x MON87708 x MON89788, NA], A471: [Soy, MON87769, MON87769-7, NA], A472: [Soy, MON87769 x MON89788, MON-87769-7 x MON-89788-1, NA], A473: [Soy, MON89788, MON-89788-1, Genuity (Registered trademark) Roundup Ready 2 Yield (trademark)], A474: [soybean, SYHT0H2, SYN-000H2-5, Herbicide-tolerantSoybeanline], A475: [soybean, W62, ACS -GM002-9, LibertyLink ™ soybean], A476: [Soy, W98, ACS-GM001-8, LibertyLink ™ soybean], A477: [Soy, OT96-15, OT96-15, NA], A478: [Pepo Pumpkin (Cucurbitapepo), CZW3, SEM-0CZW3-2, NA], A479: [Pepo Pumpkin (Cucurbita pepo), ZW20, SEM-0ZW20-7, NA], A480: [Sugar beet, GTSB77 (T9100152), SY-GTSB77 -8, InVigor ™ sugarbeet], A481: [sugar beet, H7-1, KM-000H71-4, Roundup Ready ™ sugarbeet], A482: [sugar beet, T120-7, ACS-BV001-3, LibertyLink ( Sugarbeet], A483: [sugar cane, CTB141175 / 01-A, CTB141175 / 01-A, NA], A484: [sugar cane, NXI-1T, NXI-1T, NA], A485: [sugar cane, NXI-4T, NXI-4T, NA], A486: [sugar cane, NXI-6T, NXI-6T, NA], A487: [sunflower, X81359, X81359, Clearfield® Sunflower], A488: [sweet pepper, PK-SP01, X81359, NA], A489: [Tobacco, C / F / 93 / 08-02, NA, NA], A490: [Tobacco, Vector21-41, NA, NA ], A491: [Tomato, 1345-4, NA, NA], A492: [Tomato, 35-1-N, NA, NA], A493: [Tomato, 5345, NA, NA], A494: [Tomato, 8338] , CGN-89322-3, NA], A495: [Tomato, B, SYN-0000B-6, NA], A496: [Tomato, Da, SYN-000DA-9, NA], A497: [Tomato, DaDongNo9, NA , NA], A498: [Tomato, F (1401F, h38F, 11013F, 7913F), SYN-0000F-1, FLAVRSAVR (TM)], A499: [Tomato, FLAVRSAVR, CGN-89564-2, FLAVRSAVR (TM)] , A500: [Tomato, HuafanNo1, NA, NA], A501: [Tomato, PK-TM8805R (8805R), NA, NA], A502: [Wheat, MON71800, MON-71800-3, RoundupReady (TM) wheat], A503: [Wheat, AP205CL, AP205CL, Clearfield (registered trademark) Wheat], A504: [Wheat, AP602CL, AP602CL, Clearfield (registered trademark) Wheat], A505: [Wheat, BW255-2 x BW238-3, BW255-2 x BW238-3, Clearfield (registered trademark) Wheat], A506: [Wheat, BW7, BW7, Clearfield (registered trademark) Wheat], A507: [Wheat, Teal11A, Teal11A, Clearfield (registered trademark) ) Wheat], A508: [Wheat, SWP965001, SWP965001, NA], A509: [Maize, NA, NA, Agrisure Artesian (TM)], A510: [Maize, NA, NA, Optimum (R) AQUAmax (R) )], A511: [Canola, NA, NA, SU canola (R)], A512: [Canola, NA, NA, Nexera (R) Canola], A513: [Soy, NA, NA, STS soybean], A514: "Maize, NA, NA, SR corn", A514: "Sunflower, NA, NA, ExpressSun (registered trademark)", A515: [Rice, NA, NA, Golden rice], A516: [Maize, NA, NA, NA , Poast Protected (registered trademark) corn], A517: [Sunflower, NA, NA, ExpressSun (registered trademark)], A518: [Rice, NA, NA, Provisia (Rice) Rice], A519: [canola, NA, NA , Triazinon Tolerant Canola], A520: [Maize, NA, NA, SmartStax (registered trademark) Pro], A521: [Soy, NA, NA, Credenz (registered trademark) soybean], A522: [Maize, TC1507 x 59122, DAS -01507-1 × DAS-59122-7, Optimum® AcreMax® 1], A523: [Maize, 4114 x MON810 x MIR604, DP-0
04114-3 × MON-00810-6 × SYN-IR604-5, Qrome (trademark)], A524: [Water, NA, NA, Stoneville (registered trademark) Cotton ST5517GLTP], A525: [Water, NA, NA, Stoneville (Registered trademark) Cotton ST4848GLT], A526: [cotton, NA, NA, Stoneville (registered trademark) Cotton ST4949GLT], A527: [cotton, NA, NA, Stoneville (registered trademark) Cotton ST5020GLT], A528: [cotton, NA , NA, Stoneville (registered trademark) Cotton ST5115GLT], A529: [Water, NA, NA, Stoneville (registered trademark) Cotton ST6182GLT], A530: [Water, NA, NA, Stoneville (registered trademark) Cotton ST4747GLB2], A531: [Water, NA, NA, Stoneville (registered trademark) Cotton ST4946GLB2], A532: [cotton, NA, NA, Stoneville (registered trademark) Cotton ST6448GLB2], A533: [soy, NA, NA, Enlist E3 (trademark)], A534: [Soy, NA, NA, Enlist (R) Roundup Ready 2 Yield (R)], A535: [Maize, NA, NA, Enlist (R) Roundup Ready (R) Corn 2], A536: [Maize , NA, NA, Smartstax (registered trademark) Enlist (trademark) ], A537: [Maize, NA, NA, Powercore (registered trademark) Enlist (trademark)], A538: [Catalyst, NA, NA, Enlist (trademark) Cotton], A539: [Cat, NA, NA, Bollgard ( (Registered trademark) 3 XtendFlex (registered trademark)], A540: [corn, NA, NA, SmartStax (registered trademark) RIB Complete (registered trademark) Corn], A541: [corn, NA, NA, VT Double PRO (registered trademark)] RIB Complete (registered trademark) Corn], A542: [corn, NA, NA, VT Double PRO (registered trademark) Corn], A543: [corn, NA, NA, Genuity (registered trademark) VT Triple PRO (registered trademark) RIB] Complete Corn], A544: [Maize, NA, NA, Trecepta (TM) Corn], A545: [Soy, NA, NA, Fukuminori], A546: [Soy, NA, NA, Yumeminori], A547: [Maize, NA, NA, ZFN-12 maize], A548: [rice, NA, NA, Yumepirika], A549: [rice NA, NA, Kanto BPH1], A550: [Water, NA, MON88702, NA], A551: [Soybean, DP305423 x MON87708, DP-305423-1 x MON-87708-9, NA], A552 : [Soybean, DP305423 x MON87708 x MON89788, DP-305423-1 x MON-87708-9 x MON-89788-1, NA], A553: [Soybean, DP305423 x MON89788, DP-305423-1 x MON-89788- 1, NA], A554: [cotton, 3006-210-23 x 281-24-236 x MON88913 x COT102 x 81910, DAS-21023-5 x DAS-24236-5 x MON-88913-8 x SYN-IR102- 7], A555: [cotton, GHB811, BCS-GH811-4, NA], A556: [sorghum, NA, NA, Igrowth ™].

  In the present invention, the composition of the present invention can be applied to the above-mentioned modified plants A1 to A556 or cultivated areas thereof. When the composition of the present invention is applied to the above-mentioned plants, it is more preferable to apply the composition to its seeds and vegetative reproductive organs.

  In practicing the method of the present invention, the main drug substance and the trace drug substance are applied to places where pests are or will occur. Examples of the method of applying the main drug substance and the trace drug substance include a method of spraying the composition of the present invention on soil and a method of spraying the composition of the present invention on weeds. The spraying is usually performed by diluting the composition of the present invention with water, and the spraying water amount is not particularly limited, but is usually in the range of 10 to 5000 L / ha, preferably 100 to 500 L / ha, more preferably 140 to 300 L / ha. It is.

Application rates of main raw material and trace drug substance as the total amount, typically 10000 m ² per 1～5000G, preferably 2~2000g per 10000 m ^2, more preferably 5~1000g per 10000 m ^2. Specifically, 3 g, 4 g, 7 g, 10 g, 15 g, 20 g, 30 g, 40 g, 50 g, 70 g, 80 g, 100 g, 150 g, 200 g, 300 g, 400 g, 500 g, 700 g, 800 g, 1500 g, 3000 g per 10,000 m ² And 4000 g. When the seed is treated, 0.2 g, 0.5 g, 1 g, 2 g, 5 g, 10 g, 20 g, 50 g, 100 g, 200 g, 500 g and the like can be mentioned per 100 kg seed.

  In the method of the present invention, the main drug substance and the trace drug substance may be mixed with an adjuvant and applied. The type of adjuvant is not particularly limited, but oils such as Agri-Dex and MSO, nonionics (e.g., esters or ethers of polyoxyethylene) such as Indus, anionics (substituted sulfonates) such as Gramine S, and Genamine T Cationic (polyoxythyleneamine) such as 200BM, and organic silicon such as Silwet L77.

  The pH and hardness of the spray liquid prepared when carrying out the method of the present invention are not particularly limited, but are usually in the range of pH 5-9 and the hardness is usually in the range of 0 to 500.

  The time zone for carrying out the method of the present invention is not particularly limited, but is usually in the range of 5:00 am to 9:00 pm, and the photon flux density at the place of application is usually 10 to 2500 micromol / m 2 / sec.

When the composition of the present invention is applied to a crop field, the composition of the present invention may be applied to crop seeds, or the composition of the present invention may be applied to a field before sowing of the crop seeds. The composition of the present invention may be applied to the field at the same time and / or after sowing.
When applying the composition of the present invention before sowing of agricultural crop seeds, 50 days before sowing to immediately before sowing, preferably 30 days to just before sowing, more preferably 20 days before sowing to just before sowing, further preferably before sowing. The composition of the present invention is applied from 10 days to immediately before sowing.
When the composition of the present invention is applied after seeding of agricultural crop seeds, the composition of the present invention is usually applied immediately after sowing to before harvesting. More preferably, immediately after sowing to before emergence, during the true leaf 1 to 6 leaf stages of the crop, and / or during the flowering / fruit setting stage.
The case where the composition of the present invention is applied simultaneously with the seeding of the crop seed is the case where the seeder and the sprayer are integrated.

  In the practice of the method of the present invention, a preparation containing a main drug substance and a trace drug substance as active ingredients can be used after being diluted with water. Further, a preparation containing a main drug substance as an active ingredient as an active ingredient and another preparation containing a trace drug substance may be mixed and used. Further, a formulation containing a main drug substance and a trace drug substance as active ingredients, and a formulation containing other pesticidal compounds as active ingredients may be mixed and used.

  The pests of the present invention include harmful arthropods such as weeds, phytopathogenic microorganisms, harmful insects, harmful mites, harmful molluscs, harmful nematodes, and the like.

  Examples of weed species that can be controlled by the composition of the present invention include, but are not limited to, the following.

Stinging nettle (Urticaceae): Urtica urens
Polygonaceae (Polygonaceae): Polygonum convolvulus, Polygonum lapathifolium, Polygonum pensylvanicum, Polygonum persicaria, Polygonum longisetum, Polygonum longisetum , Knotweed (Polygonum cuspidatum), Rubix (Rumex japonicus), Rumex crispus, Rumex obtusifolius, Rubix (Rumex acetosa)
Purslane Weed (Portulacaceae): Purslane (Portulaca oleracea)
Caryophyllaceae: Stellaria media, Stellaria aquatica, Cerastium holosteoides, Cerastium glomeratum, Spergula arvensis, Silene gall
Pomegranate Weeds (Molluginaceae):
Chenopodiaaceae: Chenopodium album, Chenopodium ambrosioides, Butterfly (Kochia scoparia), Hijiki Nohara (Salsola kali), Atriplex spp.

Amaranthaceae: Amaranthus retroflexus, Amaranthus viridis, Amaranthus lividus, Amaranthus spinosus, Amaranthus hybridus, Amaranthus hybridus ant Amaranthus patulus, Amaranthus tuberculatus = Amaranthus rudis = Amaranthus tamariscinus, Amaranthus blitoides, Haibiyu (Amaranthus deflexus), Amaranthus aerant, Almaranthus aerant, Amaranthus au genus ), Sanguinaria (Alternanthera tenella)
Poppy Weeds (Papaveraceae): Papaver rhoeas, Papaver dubium, Azamige (Argemone mexicana)
Brassicaceae: Brassicaceae: Radish (Raphanus raphanistrum), Radish (Raphanus sativus), Radish (Sinapis arvensis), Nasuna (Capsella bursa-pastoris), Brassica juncea, Brassica napus (Brassica napus) (Descurainia pinnata), Squashes burdock (Rorippa islandica), Killer's crow (Rorippa sylvestris), Gumbinazna (Thlaspi arvense), Miyagashi (Myagrum rugosum), Mamegunbana (Lepidium virginicum), Karaxana mus
Weeds (Capparaceae): Cleome affinis

Legume weeds (Fabaceae): Kusanem (Aeschynomene indica), Zigzag joint vetch (Aeschynomene rudis), Red horned foxtail (Sesbania exaltata), Ebisugusa (Cassia obtusifolia), Habasou (Cassia occidentalis), Juzohagi (Desmo) adscendens), Desmodium illinoense, Trifolium repens, Pueraria lobata, Vicia angustifolia, Indigofera hirsuta, Indigofera hirsella nx Vigna sinensis)
Oxalidaceae: Oxalis corniculata, Oxalis strica, Oxalis oxyptera
Anthracnose weeds (Geraniaceae): American aurora (Geranium carolinense), Dutch aurora (Erodium cicutarium)
Euphorbiaceae Weeds (Euphorbiaceae): Euphorbia helioscopia, Euphorbia maculata, Euphorbia humistrata, Euphorbia esula, Euphorbia brassicae, Euphorbia heterophylla (Acalypha australis), Tropic croton (Croton glandulosus), Lobdo croton (Croton lobatus), Brazilian citrus (Phyllanthus corcovadensis), Castor bean (Ricinus communis)

Malvaceae Weeds: Abutilon theophrasti, sika deer (Sida rhombiforia), marba sika deer (Sida cordifolia), American sika deer (Sida spinosa), Sida glaziovii (Sida glaziovii), Sida santaremensis (Sida santaremnen) ), Ginseng (Hibiscus trionum), Western mallow (Anoda cristata), Enoki mallow (Malvastrum coromandelianum)
Onabraceae Weeds: Ondaceae (Ludwigia epilobioides), Lumbwigia octovalvis, Lutwigia decurre, Oenothera biennis, Oenothera laciniata
Sterculiaceae Weed (Waltheria indica)
Violaceae Weed: Vicia arvensis, Wild Pansy (Viola tricolor)
Cucurbitaceae: Cucurbitaceae: Arechiuri (Sicyos angulatus), Wild Cucumber (Echinocystis lobata), Wild Bittern (Momordica charantia)
Lythraceae: Ameminia multiflora, Ammannia auriculata, Ammannia coccinea, Lythrum salicaria, and Rota indica
Dipterocarpaceae Weed (Elatinaceae): Dipterocarp (Elatine triandra), California Water Wort (Elatine californica)

Apiaceae: Apiaceae (Oenanthe javanica), Nolan ginseng (Daucus carota), Dokunin ginseng (Conium maculatum)
Araliaceae Weeds (Hydrocotyle sibthorpioides), Brazil Phytophthora (Hydrocotyle ranunculoides)
Pinaceae Weeds (Ceratophyllaceae): Pinus (Ceratophyllum demersum)
Red-backed weed (Cabombaceae): Red-backed peach (Cabomba caroliniana)
Arinophoraceae Weeds (Haloragaceae): Greater Samoan (Myriophyllum aquaticum), Fusamo (Myriophyllum verticillatum), Water Millfoils (Myriophyllum spicatum, Myriophyllum heterophyllum, etc.)
Sapindaceae: Cardiospermum halicacabum
Primulaceae: Primulaceae: Anagallis arvensis
Asclepiadaceae: Asclepias syriaca, Honey Vine Milkweed (Ampelamus albidus)
Rubiaceae Weeds (Rubiaceae): Catchweed Bed Straw (Galium aparine), Yaemgra (Galium spurium var.

Convolvulaceae: Convolvulaceae: morning glory (Ipomoea nil), American morning glory (Ipomoea hederacea), malva morning glory (Ipomoea purpurea), Malva American morning glory (Ipomoea hederacea var. Integriuscula), mameasa laga (Iosa moa) , Noasagao (Ipomoea acuminata), Tutanoharukou (Ipomoea hederifolia), Marbarukou (Ipomoea coccinea), Rukosou (Ipomoea quamoclit), Ipomoea grandifolia (Ipomoea grandifolia), Ipomoea alipostia alopoia Convolvulus arvensis, Convolvulus arvensis, Convolvulus arvensis, Convolvulus arvensis, Convolvulus arvensis, Convolvulus arvensis, Convolvulus arvensis, Convolvulus arvensis, Convolvulus arvensis, Convolvulus arvensis, Convolvulus arvensis, Convolvulus arvensis, Convolvulus arvensis, Convolvulus arvensis a cissoides), Okinawa morning glory (Jacquemontia tamnifolia)
Purple Weed (Boraginaceae): Forget-me-not (Myosotis arvensis)
Lamiaceae Weeds (Lamiaceae): Lamium purpureum, Laminium amplexicaule, Lemonis nepetaefolia, Hyptis suaveolens, Hyptis lophanta, eon urus gibbon

Solanaceae weeds (Solanaceae): Datura stramonium, Solanum nigrum, Terimino dogwood (Solanum americanum), American dogwood (Solanum ptycanthum), Kinewoodwood (Solanum sarraides) , Kingfisher (Solanum aculeatissimum), Wild tomato (Solanum sisymbriifolium), Warnasubi (Solanum carolinense), Sennari physalis (Physalis angulata), Smooth ground cherry (Physalis subglabrata), Giant squirrel (Nicandra physaloides)
Scrophulariaceae: Scrophulariaceae: Veronica hederaefolia, Veronica persica, Veronica arvensis, Azena (Lindernia procumbens), Azena (Lindernia dubia), Azenia nia opa gus (Dopatrium junceum), giant abalone (Gratiola japonica),
Plantain Weeds (Plantaginaceae): Plantain (Plantago asiatica), Plantain lanceolata, Plantain major (Plantago major), Mizuhakobe (Callitriche palustris)

  Asteraceae: Asteraceae: Xanthium pensylvanicum, Xanthium occidentale, Xanthium falcon (Xanthium italicum), wild sunflower (Helianthus annuus), chamomile (Matricaria chamomilla), Matricaria chamomant (Matricaria chamomantata) ), Oriental Magpie (Matricaria matricarioides), Artemisia princeps, Artemisia vulgaris, Artemisia verlotorum, Artemisia verlotorum, Solidago altissima, Taraxacumtaga, Taraxacum officale, Taraxacum officale (Galinsoga parviflora), noborigine (Senecio vulgaris), Senecio brasiliensis (Senecio brasiliensis), Senecio grisebachii (Senecio grisebachii), aretinogi (Conyza bonariensis), giant antler (C) onyza smatrensis), Conyza canadensis, Ragweed (Ambrosia artemisiaefolia), Kwamodoki (Ambrosia trifida), Tawkogi (Bidens tripartita), Bidens pilosa, Bidens subsuna (Bidens subs) Thistle (Cirsium arvense), American Thistle (Cirsium vulgare), Maria Thistle (Silybum marianum), Masked Tistle (Carduus nutans), Sticky Pear (Lactuca serriola), Nogeshi (Sonchus oleraceus), Oninogeshi (Sonchus aspings) Wedelia glauca), perforated black foot (Melampodium perfoliatum), red croaker (Emilia sonchifolia), Shiozakisou (Tagetes minuta), paracles (Blainvillea latifolia), Kotobukigi (Tridax procumbens), Yerba po Rosa (Porophyllum ruderale), Paraguay star bar (Acanthospermum australe), Bristolie star bar (Acanthospermum hispidum), Scarlet crab (Cardiospermum halicacabum), Cuckoo thistle (Ageratum conyzoides), Common bone set (Eupatorium perfoli) , Dandborogiku (Erechtites hieracifolia), American Everlasting (Gamochaeta spicata), Vladimir japonicus (Gnaphalium spicatum), Jageria Hitra (Jaegeria hirta), Sesamekart (Parthenium hysterophorus), Menagomi (Siegesbeckis oralis), Takasaburo (Eclipta prostrata), American Takasaburo (Eclipta alba), Goldfish (Centipeda minima),

Almodataceae Weeds (Alismataceae): Urikawa (Sagittaria pygmaea), Omodaka (Sagittaria trifolia), Greater Omodaka (Sagittaria sagittifolia), Tailing Omodaka (Sagittaria montevidenasis), Aginashi (Sagittaria aginada mosquito algiosa) aquatica)
Yellow smelt family (Limnocharitaceae): Yellow smelt (Limnocharis flava)
Hydrocharitaceae: Frogbit (Limnobium spongia), Chromo (Hydrilla verticillata), Common Water Nymph (Najas guadalupensis)
Araceae Weed (Araceae): Pistia stratiotes
Lemaceae Weeds (Lemnaceae): Duckweed (Lemna aoukikusa), Duckweed (Spirodela polyrhiza), Daphnia duckweed (Wolffia spp)
Beetle family weed (Potamogetonaceae): Beetle (Potamogeton distinctus), Pondweeds (Potamogeton crispus, Potamogeton illinoensis, Stuckenia pectinata, etc.)
Liliaceae: Wild Onion (Allium canadense), Wild Garlic (Allium vineale), Nobile (Allium macrostemon)
Water Mallow Weeds: Water Hyacinth (Eichhornia crassipes), American Eel (Heteranthera limosa), Water Ole (Monochoria korsakowii), Eel (Monochoria vaginalis)
Commelinaceae Weeds (Commelinaceae): Commelina communis, Commelina bengharensis, Elect Dayflower (Commelina erecta), Ilexa (Murdannia keisak)

  Poaceae Weeds: Echinochloa crus-galli, Echinochloa oryzicola, Echinochloa crus-galli var formosensis, Late Watergrass (Echinochloa oryzoides), Echinochloa colony (Echinochloa colon) Echinochloa crus-pavonis, Enocologna (Setaria viridis), Achinokonokorogosa (Setaria faberi), Kinenokoro (Setaria glauca), American Enokorogosa (Setaria geniculata), Meishishiba (Digitaria ciliaris), Large crabgrass (Digitaria sanguinalis), Myrtle crab (Digitaria sanguinalis) Digitaria horizontalis), Japanese grasshopper (Digitaria insularis), Japanese hawk (Eleusine indica), Poa annua, Poa annua, Poa trivialis, Poa pratensis, Alospecurus aequal opecurus myosuroides, oats (Avena fatua), sorghum sorghum (Sorghum halepense), shatter cane (Sorghum vulgare), barley (Agropyron repens), barley (Lolium multiflorum), barley (Lolium perenne), and boum (Lolium) Bromus catharticus), Arechinohikiki (Bromus sterilis), Suzumechanikiki (Bromus japonicus), Ravenwood (Bromus secalinus), Umanohakiki (Bromus tectorum), Hosonogemugi (Hordeum jubatum), Goatberry (Aegilopsace linus) Kusayoshi (Phalaris minor), Silky Bentgrass (Apera spica-venti), Okusakiki (Panicum dichotomiflorum), Texas Panicum (Panicum texanum), Gineakibi (Panicum maximum), Meriken acne (Brachiaria platyphylla), Ruzigrass (Brachiaria zi) , Alexandergrass (Brachiaria plantaginea), Surinamegrass (Brachiaria decumbens), Palisadegrass (Brachiaria brizantha), Colombian grass (Brachiaria humidicola), Cinrus noiga (Cenchrus echinatus), Crimrus noiga (Cenchrus pauciflorus), Narcovipe (Eriochpeni um) setosum), African bearded moss (Chloris gayana), bearded moss (Chlorisvirgata), onion dust (Eragrostis pilosa), rubygaya (Rhynchelitrum repens), skull frog (Dactyloctenium aegyptium), wild squirrel (Ischaemum gozasa (Ischaemum rugosum) Oryza sativa), American spruce budworm (Paspalum notatum), Coastal sandpaspalm (Paspalum maritimum), Kushweed spruce (Paspalum distichum), Kikuyugrass (Pennisetum clandestinum), Hosobatachikara Ba (Pennisetum setosum), horned reeds (Rottboellia cochinchinensis), Azegaya (Leptochloa chinensis), Oniazegaya (Leptochloa fascicularis), Itoazegaya (Leptochloa filiformis), Amazon sprangle top (Leptochloa panicaia, Leptochloa panicaia) , Glyceria leptorrhiza, Glyceria acutiflora, Greyceria maxima, Agrostis gigantea (Agrostis gigantea), and Agrosida gallium (Agroa sylvania) , Centipede (Eremochloa ophiuroides), Fenuca arundinacea, Fenuca rubra (Festuca rubra), Imperata cylindrica, Miscanthus sinensis, Switchgrass (Panicum virgatum), Bas (Zoysia japonica)

Cyperaceae Weeds (Cyperaceae): Cyperus microiria, Cyperus iria, Cyperus compressus, Cyperus difformis, Cyperus flaccidus, Cyperus flaccidus, Cyperus flaccidus (Cyperus odoratus), Cyperus serotinus, Cyperus rotundus, Yellow sedge (Cyperus esculentus), Cyperus esculentus (Kyllinga gracillima), Eidakug (Kyllinga brevifolia), Hiderico mis (charb) acicularis), kuroguwai (Eleocharis kuroguwai), fireflies (Schoenoplectiella hotarui), dog fireflies (Schoenoplectiella juncoides), taiwanmai (Schoenoplectiella wallichii), swordfish (Schoenoplectiella mucronatus), kangare (Schoenoplectiella triangulatus), pulp (Schoenoplectiella nipponicus), Sankakui (Schoenoplectiella triqueter), Koukiyagara (Bolboschoenus koshevnikovii), Ukiyagara (Bolboschoenus fluviatilis)
Equisetaceae: horsetail (Equisetum arvense), dogwood (Equisetum palustre)
Salamander Weed (Salviniaceae): Salamander (Salvinia natans)
Azollaceae Weed (Azollaceae): Azolla japonica, Azolla imbricata
Marblesaceae (Marsileaceae): Marsileaceae (Marsilea quadrifolia)
Others: Filamentous algae (Pithophora, Cladophora), moss, moss, hornwort, cyanobacteria, ferns, perennial crops (nuts, stones, berries, nuts, citrus, hops, grapes, etc.) Sucker.

  Regarding the above weeds, intra-species variation is not particularly limited. That is, those in which the sensitivity to a specific herbicide is reduced (also referred to as showing resistance) are also included. The decrease in sensitivity may be due to a mutation at the target site (action point mutation) or may be due to a factor other than the action point mutation (non-action point mutation). An action point mutation is a mutation in a nucleic acid sequence portion (open reading frame) corresponding to the amino acid sequence of a protein, in which an amino acid substitution has occurred in the protein as a target site, deletion of a suppressor sequence in a promoter region, and deletion of an enhancer sequence. Includes those in which the protein at the target site is overexpressed due to amplification or mutation such as an increase in the copy number of the gene.

  Factors that reduce sensitivity due to non-effect point mutations include metabolic enhancement, malabsorption, translocation dysfunction, and excretion out of the system. As an example of a factor of metabolism enhancement, an activity of a metabolic enzyme such as cytochrome P450 monooxygenase, arylacylamidase, esterase, and glutathione S transferase is increased. Out-of-system efflux includes transport to the vacuole by the ABC transporter.

  Examples of herbicide-resistant weeds include:

Glyphosate resistance:
As an example of the decrease in sensitivity of a weed due to the action point mutation, a weed having a mutation that causes one or more of the following amino acid substitutions in the EPSPS gene is given. Thr102Ile, Pro106Ser, Pro106Ala, Pro106Leu. According to the present invention, ohibashi, mugwort, barley, barnacle grass, water skimp, water hemp, and so on, which have one or more of these mutations (for example, a double mutation of Thr102Ile and Pro106Ser), can be effectively controlled. Similarly, examples of glyphosate resistance due to an action point mutation include an increase in the copy number of the EPSPS gene. INDUSTRIAL APPLICABILITY The present invention can effectively control glyphosate-resistant ginkgo biloba, water hemp, squirrel, etc., whose EPSPS gene copy number has been increased. Examples of decreased weed susceptibility due to the non-action point mutation include glyphosate-resistant ginkgo sprouts, oleoresinum, and aretinogus which are associated with the ABC transporter, and these are effectively controlled by the present invention.

ALS-inhibiting herbicide resistance:
Examples of the decrease in sensitivity of a weed due to an action point mutation include a weed having a mutation that causes one or more of the following amino acid substitutions in the ALS gene. Ala122Thr, Ala122Val, Ala122Tyr, Pro197Ser, Pro197His, Pro197Thr, Pro197Arg, Pro197Leu, Pro197Gln, Pro197Ala, Pro197Ile, Ala205Val, Ala205Phe, Asp376Glu, Asp376Gln, Asp376Asn, Arg377His, TrpGr, SrpGr, TrpGrp According to the present invention, ALS inhibitor-resistant Aogatoi, Honagaoageoto, Honokaaoagetoi, water hemp, pomegranate and the like having these action point mutations are effectively controlled. An example of a decrease in the sensitivity of a weed due to the non-effect point mutation includes a weed that has become resistant to an ALS inhibitor due to the involvement of CYP or GST, and these are effectively controlled by the present invention. Examples of such known are a pearl bark overexpressing CYP81A10 and CYP81A1v1, an Arabidopsis overexpressing CYP81A12 and CYP81A21, and a giant scallop overexpressing GSTF1 and GSTU2.

ACCase inhibitor resistance:
An example of a decrease in the sensitivity of a weed due to an action point mutation is a weed having a mutation that causes one or more of the following amino acid substitutions in the ACCase gene. Ile1781Leu, Ile1781Val, Ile1781Thr, Trp1999Cys, Trp1999Leu, Ala2004Val, Trp2027Cys, Ile2041Asn, Ile2041Val, Asp2078Gly, Cys2088Arg, Gly2096Ala. According to the present invention, ACCase-resistant weeds having these action point mutations can be effectively controlled. An example of a decrease in the sensitivity of a weed due to the non-action point mutation is a weed that has become resistant to an ACCase inhibitor due to the involvement of CYP or GST, and these are effectively controlled by the present invention. Examples of such known are a pearl bark overexpressing CYP81A10 and CYP81A1v1, an Arabidopsis overexpressing CYP81A12 and CYP81A21, and a giant scallop overexpressing GSTF1 and GSTU2.

PPO inhibitor resistance:
As an action point mutation, a mutation that causes one or more of the following amino acid substitutions in the PPO gene is known as a resistance mutation of carfentrazone-ethyl, fomesafen or lactofen, or is predicted to be a resistance mutation Is done. Arg128Leu, Arg128Met, Arg128Gly, Arg128His, Arg128Ala, Arg128Cys, Arg128Glu, Arg128Ile, Arg128Lys, Arg128Asn, Arg128Gln, Arg128Ser, Arg128Thr, Arg128Val, Arg128Tl, Gly210, LyGl, Gly210, LyGl, Gly210 All numbers are standardized by the sequence of PPO2 of Amaranthus palmeri). Usually, PPO1 and PPO2 are present in PPO of weeds, but the mutation may be present in either PPO1 or PPO2 or in both. It is preferably a case where PPO2 has a mutation. For example, Arg128Met means that the 128th amino acid has a mutation. Arg128Leu is known as Arg98Leu in PPO2 of ragweed (Weed Science 60, 335-344), Arg128Met is known in PPO2 of P. japonicus (Pest Management Science 73, 1559-1563), and Arg128Gly is P. (Pest Management Science 73, 1559-1563) and water hemp PPO2 (Pest Management Science, doi: 10.1002 / ps.5445), and Arg128Ile and Arg128Lys are known as water hemp PPO2 (Pest Management Science, doi: 10.1002 / ps.5445), Arg128His is known as Arg132His in PPO2 of Boeing (WSSA annual meeting, 2018), and Gly114Glu, Ser149Ile and Gly399Ala are known in PPO2 of Blue-winged Blueberry (Frontiers in Plant Science 10, Article 568), Ala210Thr is known as Ala212Thr in PPO1 of Ohishiba (WSSA annual meeting, 2019). PPO inhibitor-resistant weeds having these action point mutations are not limited to the aforementioned weed species. That is, PPO1 or PPO2 Arg128Leu, Arg128Met, Arg128Gly, Arg128His, Arg128Ala, Arg128Cys, Arg128Glu, Arg128Ile, Arg128Lys, Arg128Asn, Arg128Gln, Arg128Ser, Arg128Thr, ArgGr, 210, LyGr, 210, LyGlA, Gly, ArG128, LygAlGr, 210, Lyg , Ser149Ile or Gly399Ala mutation, but also water hemp, ragweed having the mutation, Drosophila having the mutation, etc. can be effectively controlled. As non-action point mutations, water hemp that has become resistant to PPO inhibitors due to the involvement of CYP or GST, and water hemp that has become resistant to carfentrazone-ethyl, such as P. pallidum, are known ( PLOS ONE, doi: 10.1371 / journal.pone.0215431), but they are also effectively controlled.

  Auxin herbicide resistance: Action point mutations include mutations that cause Gly-Asn in the degron region of the AUX / IAA gene. Butterflies, Pleurotus corviformis and water hemp having this mutation are glyphosate resistant and can be effectively controlled. As non-action point mutations, dicamba-resistant scrophium and 2,4-D-resistant water hemp, which are suggested to be involved in CYP, are also effectively controlled. The same applies when GST is involved.

Auxin herbicide resistance:
Examples of the action point mutation include a mutation causing Gly-Asn in the degron region of the AUX / IAA gene. According to the present invention, pests, water-bottled squirrels and water hemp having this mutation are effectively controlled. Examples of non-effect point mutations include dicamba-resistant blue-chestnuts and 2,4-D-resistant water hemp, suggesting the involvement of CYP, and these are effectively controlled by the present invention. The same applies to non-effect point mutations involving GST.

HPPD inhibitor resistance:
Examples of decreased weed susceptibility due to non-effect point mutations include water hemp and scutellaria, which are involved in CYP or GST and become resistant to HPPD inhibitors. Controlled. As an example of these, A. pallidum overexpressing CYP72A219, CYP81B and CYP81E8 is known.

Photosystem II inhibitor resistance:
An example of a decrease in the sensitivity of a weed due to an action point mutation is a weed having a mutation that causes one or more of the following amino acid substitutions in the psbA gene. Val219Ile, Ser264Gly, Ser264Ala, Phe274Val. According to the present invention, the photochemical system II inhibitor-resistant Rhododendron aegypti and water hemp having these action point mutations can be effectively controlled. Examples of decreased sensitivity of weeds due to non-effect point mutations include CYP, GST, or AAA, which are associated with photosystem II inhibitors and are resistant to photosystem II inhibitors. Is effectively controlled. As an example of these, a worm that overexpresses CYP71R4 is known.

Glutamate synthase inhibitor resistance:
An example of a decrease in the sensitivity of a weed due to an action point mutation is a weed having a mutation that causes an amino acid substitution of Asp171Asn in the glutamine synthase gene. According to the present invention, a glutamine synthase inhibitor-resistant giant moth, water hemp, etc. having this mutation can be effectively controlled. Examples of decreased sensitivity of weeds due to non-effect point mutations include G. serrata and water hemp, which have become glufosinate resistant due to CYP or GST, but these are effectively controlled by the present invention. . As an example of these, A. pallidum overexpressing CYP72A219, CYP81B and CYP81E8 is known.

  Resistant weeds are two or more of the above groups (arbitrarily selected two groups, arbitrarily selected three groups, arbitrarily selected four groups, arbitrarily selected five groups, arbitrarily selected six groups) , 7 and 8) can be effectively controlled even if they are "stuck" (stacked) resistant weeds. Examples of stacked resistant weeds include water hemp, which is resistant to all photosystem II inhibitors, HPPD inhibitors, 2,4-D, PPO inhibitors, ALS inhibitors, and glyphosate. Controlled. The stack may be a combination of action point mutations, a combination of non-action point mutations, or a combination of action mutations and non-action point mutations.

  The composition of the present invention can control harmful arthropods, harmful molluscs and harmful nematodes such as harmful insects and harmful mites. Specifically, the following are mentioned, for example.

  Hemiptera: Brown planthopper (Laodelphax striatellus), brown planthopper (Nilaparvata lugens), brown planthopper (Sogatella furcifera), corn planthopper (Peregrinus maidis), yellow-tailed mosquito (Javesella pellucida), black moss Planthopper (Delphacidae); Leafhopper (Nephotettix cincticeps); Leafhopper (Nephotettix virescens); , Corn leaf hoppers (Dalbulus maidis), white leafhoppers (Cofana spectra), Amrasca biguttula biguttula, etc., leafhoppers (Cicadellidae); European spitol bugs (Philaenus spumarius), etc .; Kogashi Araceae (Cercopidae); bean aphids (Aphis fabae), soybean aphids (Aphis glycines), cotton aphids (Aphis gossypii), European apple aphids (Aphis pomi), snowy aphids (Aphis spiraecola), ), Barley aphid aphid (Brachycaudus helichrysi), radish aphid (Brevicoryne brassicae), rosy apple aphid (Dysaphis plantaginea), red radish aphid (Lipaphis erysimi), tulip beetle (Macrosiphum aurum) The aphid (Nasonovia ribisnigri), the wheat aphid (Rhopalosiphum padi), the corn aphid (Rhopalosiphum maidis), the citrus black aphid (Toxoptera citricida), Aphididae (Dakifolia sera), Aphididae (Dakifolia serrata), Aphididae (Dakifolia phylla) (Phylloxera devastatrix), Pecan leaf phylloxera (Phylloxera notabilis), Southern pecan leaf phylloxera (Phylloxera russelae), etc .; Phylloxeridae; Aphid family (Adelgidae) such as aphids (Aphrastasia pectinatae); Stink bugs (Eysarcoris lewisi), white stink bugs (Eysarcoris ventralis), purple stink bugs (Eysarcoris annamita), whale stink bugs (Halyomorpha halys), southern stink bugs (Nezara viridula), and brown stink bug hersten (Euschis sting bugs) (Pentatomidae), such as (Piezodorus guildinii), Oebalus pugnax, and Dichelops melacanthus; acuta) such as Alydidae; Coleus punctiger; (Togo hemipterus), Bliss Us leucopterus), etc. (Lygaeidae); Red-spotted beetle (Trigonotylus caelestialium), Akasujisukasutemu (Stenotus rubrovittatus), Sphagnum beetle (Stenodema calcarata), Sabiirokasami (Lygaceae, Lysae) and lyricus (Lygas lyris) ); Whiteflies (Trialeurodes vaporariorum), Bemisia tabaci, Citrus whiteflies (Dialeurodes citri), Citrus whiteflies (Aleurocanthus spiniferus), Cherophyllum whiteflies (Aleurocanthus camelliae), etc. (Aleyrodidae); White-spotted scale insects (Abidillaspis cyanophylli), Red-spotted scale scales (Aonidiella aurantii), Pear-spotted scale scales (Diaspidiotus perniciosus), Pseudaulacaspis pentagona, and Unis spp. (Diaspididae) such as Unaspis citri; Coccidae such as Rubyops (Ceroplastes rubens); ); Pearacoccus solani, Phenacoccus solenopsis, Phylococcus cotyledon (Planococcus kraunhiae), Pseudococcus comstocki), Planococcus ciol occupied moss Pseudococcidae (Pseudococcidae), e.g., Pseudodococcus longispinus, Tattle Meely bug (Brevennia rehi); Rapeseed lice (Diaphorina citri); a chinensis), Potato beetle lice (Bactericera cockerelli), Piapsilla (Cacopsylla pyricola), etc .; Psyllidae; (Cimex lectularius), netite (Cimex hemipterus) and other bed bugs (Cimicidae); Quesada gigas and other semifamily (Cicadidae); (Triatoma spp.), Venezuelan green turtles (Rhodonius prolixus), and other red turtles (Reduviidae).

  Lepidoptera: Lepidoptera: Chilo suppressalis, Dark-Headed Stem Borer (Chilo polychrysus), White Stem Borer (Scirpophaga innotata), Itten-Oimeiga (Scirpophaga incertulas), Rupela albina, Cnaphalocrocis alis, Marina, pat. Riceha casino meiga (Marasmia exigua), Wata no meiga (Notarcha derogata), Awano meiga (Ostrinia furnacalis), European corn borer (Ostrinia nubilalis), Himadara no meiga (Hellula undalis), Monkuro no mega (Herpetogram tera sul) , Rice case worm (Nymphula depunctalis), sugar cane borer (Diatraea saccharalis), egg plant fruit borer (Leucinodes orbonalis), etc. (Crambidae); Pygidae family (Pyralidae) such as Emadophora batangensis and Cadra cautella; Spodoptera litura; Spodoptera exigua; Spodoptera exigua; inferens), Spodoptera mauritia, Naranga aenescens, Spodoptera frugiperda, Spodoptera exempta, Agrotis ipsilon, Agrotis ipsilon, Autographa nigris , Trichoplusia spp., Helicobacter spp. Velvet bean caterpillar (Anticarsia gemmatalis), Noctuidae (Alabama argillacea) and hop wine bowlers (Hydraecia immanis); Noctuidae (Pieridae) such as Pieris rapae; Graphholita molesta; ), Legume mini squirrel (Leguminivora glycinivorella), azukisamushiga (Matsumuraeses azukivora), apple kokumakumonamaki (Adoxophyes orana fasciata), chanokokakumamonhamaki (Adoxophyes honmai), chahamaki (Homona magnanarcomonus, homona magnanarcomonus) Alcophoraceae (Tortricidae), such as Tortricidae; , Kinmon Gracilillaridae such as Phyllonorycter ringoniella; Grasshopper family such as Carposina sasakii; Carposinidae such as Carposina sasakii; Coffee leaf minor (Leucoptera coffeella); Family (Lyonetiidae); genus Limantria (Lymantria spp.) Such as gypsy moth (Lymantria dispar); (Plutellidae); peach moth (Anarsia lineatella); Arcticidae (Arctiidae); Giant sugar cane borer (Telchin licus), etc. (Castniidae); Cossidae (Cossus insularis) and the like; Cossidae (Cossidae); and the like; Stathmopodidae such as Stathmopoda masinissa; Sphingidae such as Acherontia lachesis; spruce budgrass (Nokona feralis); Hesperiidae, such as the rice beetle (Parnara guttata);

  Thysanoptera: Thrips thrips (Frankliniella occidentalis), Thrips palmi (Thrips palmi), Thrips palmi (Thomas) Thripidae (Thripidae) such as E. thrips (Echinothrips americanus) and avocadosrips (Scirtothrips perseae);

  Diptera: Anthromycidae (Anthomyiidae), such as the fly (Delia platura), onion fly (Delia antiqua), and sugar beet fly (Pegomya cunicularia); Agromyzidae (Agromyzidae) or Chloe or Chloe (Chloe) from the family Agromyzidae; Bactrocera cucurbitae, Citrus fruit flies (Bactrocera dorsalis), Nas fly (Bactrocera latifrons), Olive fruit flies (Bactrocera oleae), Quinland fruit flies (Bactrocera tryoni), Mediterranean fruit flies (Ceratitis capitata), and Rhogo latte ) And other fruit flies (Tephriti dae); Ephrodidae, Drosophila (Drosophila) Drosophilidae (Drosophilidae); Phyllidae (Megaselia spiracularis); Phylidae; Drosophila (Clogmia albipunctata); (Sciaridae); Hemophilidae (Cecidomyiidae) such as Hessian fly (Mayetiola destructor) and Inosintometabae (Orseolia oryzae); Diopsidae (Diopsidae) such as Diopsis macrophthalma; (Simulium japonicum), Simulium damnosum Culex pipiens; Simuliidae; Phylbetominae; pallens), Culex tritaeniorhynchus, Culex pipiens f. molestus, Culex quinquefasciatus, Culex pipiens pipiens, Culex vishne es, Aedes aedicaes (Culex vishneies) ), Anopheles sinensis, Anopheles gambiae, Anopheles stephensi, Anopheles coluzzii, Anopheles albimanus, Anopheles sundaicus, Anopheles arabiensis, Anopheles funesophe, Anopheles arabiens, Anopheles funesophe Family (Culicidae); Prosimulium yezoe nsis), blackflies (Simulium ornatum), etc. (Simulidae); cattle flies (Tabanus trigonus), etc .; (Haematobia irritans), etc .; Muscidae; Calliphoridae; Sarcophagidae; Physididae (Fannidae).

  Coleoptera: Diabrotica spp., For example, Western corn rootworm (Diabrotica virgifera virgifera), Southern corn rootworm (Diabrotica undecimpunctata howardi), Northern corn rootworm (Diabrotica barberi), Mexican corn rootworm (Diabrotica virgifera zeae)), bean leaf beetle (Cerotoma trifurcata) such as banded cucumber beetle (Diabrotica balteata) and cucabit beetle (Diabrotica speciosa); (Phyllotreta striolata), Cabbage Free Beetle (Phyllotreta cruciferae), Western Black Free Beetle (Phyllotreta pusilla), Cabbage Stem Free Beetle (Psylliodes chrysocephala), Hop Free Beetle (Psylliodes punctulata), Colorado Potato Beetle (Leptinot) arsa decemlineata), rice beetle (Oulema oryzae), grape colaspis (Colaspis brunnea), corn-free beetle (Chaetocnema pulicaria), sweet potato beetle (Chaetocnema confinis), potato-free beetle (Epitrix cucumeris), igera disp. Chrysomelidae (Chrysomelidae) such as corn leaf beetle (Myochrous denticollis), beetle beetle (Laccoptera quadrimaculata) and tobacco flea beetle (Epitrix hirtipennis); seed corn beetle (Stenolophus lecontei); Family (Carabidae); Douganebubui (Anomala cuprea), Pussy beetle (Anomala rufocuprea), Aodougane (Anomala albopilosa), Bean beetle (Popillia japonica), Nagachakogane (Heptophylla picea), European mache (Rhizotro) Scarabaeidae (Scarabaeidae) such as Phyllophaga spp. Such as Holotrichia spp., June beetle (Phyllophaga crinita), and Diloboderus spp. Anthriibidae (Araecerus coffeae) and the like; Anthriibidae (Cylas formicarius) and other weevils (Aponidae); Bark beetle (Scolytidae) such as coffee berry borer (Hypothenemus hampei); weevil (Euscepes postfasciatus); alfalfa weevil (Hypera postica); Rice weevil (Echinocnemus squameus), rice weevil (Lissorhop) trus oryzophilus), Rhodobius weevil (Rhabdoscelus lineaticollis), Cottonweed weevil (Anthonomus grandis), Shibao weevil (Sphenophorus venatus), Southern corn billbug (Sphenophorus callosus), (Sphenophorus levis), genus Aracanthus (Aracanthus spp.), Such as the weevil (Scepticus griseus), the brown weevil (Scepticus uniformis), Aracanthus mourei, etc .; Occidental crabs (Tenebrionidae), such as Tribolium castaneum, Tribolium confusum, Alphitobius diaperinus, and the like, Coccinella crab (Epilachna vigintioctopuncte), such as Epilachna vigintioctopunctata, Us), Rhizopertha dominica, etc. (Bostrychidae); Leopard beetle (Ptinidae); Red-faced click beetle (Agriotes fuscicollis), red-spotted click beetle (Melanotus legatus), genus Anchostus (Anchastus spp.), Genus Conoderus (Conoderus spp.), Genus Ctenicera (Ctenicera spp.), Genus Limonius spp. (Elateridae) such as the genus (Aeolus spp.); Staphylinidae such as Paederus fuscipes; Anthrenus verbasci; ) Etc .; Dermestidae; Tobacco bug (Lasioderma serric) Orne), Sinoptera beetles (Stegobium paniceum), etc .; Anobiidae; Coleoptera helminths (Cryptolestes ferrugineus), etc .; Laemophloeidae, etc .; (Nitidulidae) such as (Brassicogethes aeneus).

  Orthoptera: Orthoptera: Locusta migratoria, Morocco locust (Dociostaurus maroccanus), Australian locust (Chortoicetes terminifera), Red locust (Nomadacris septemfasciata), Brown locust (Locustana pardalina), tree locasta or nacridium Locust (Calliptamus italicus), Differential Grasshopper (Melanoplus differentialis), Two Striped Grasshopper (Melanoplus bivittatus), Migratory Grasshopper (Melanoplus sanguinipes), Red Legged Grasshopper (Melanoplus femurrubrum), Clear Winged Grasshopper (Camnula pellucida) Mackerel grasshopper (Schistocerca gregaria), yellow winged drawcaster (Gastrimargus musicus), spursloated locust (Austracris guttulosa), cobaineago (Oxya yezoensis), scorpionfish (Ox Grasshoppers (Acrididae), such as ya japonica) and Patanga succincta; Grass family (Gryllotalpidae), such as grass (Gryllotalpa orientalis); A grasshopper (Tettigoniidae) such as mormon cricket (Anabrus simplex).

  Hymenoptera: Scorpionidae (Tenthredinidae) such as Japanese wasp (Athalia rosae) and Japanese Japanese wasp (Athalia japonica); Leaf cutting ant (Atta capiguara), etc., genus Atta spp. (Atta spp.), Genus Acromyrmex spp. Species of the genus Campus notus sp. Genus (Pogonomyrmex spp.) Such as Shugo kuari (Pogonomyrmex occidentalis), Asmania auropunctata) and other genus (Wasmania spp.), Asigamichito (Anoplolepis gracilipes) and other ant family (Formicidae); (Vespa velutina), wasps (Poestes jokahamae) and other wasps (Vespidae); momino giant bees (Urocerus gigas) and other wasps (Siricidae);

  Cockroaches (Blattodea): German cockroaches (Ectobiidae) such as German cockroaches (Blattella germanica); black cockroaches (Periplaneta fuliginosa), brown cockroaches (Periplaneta americana), small cockroaches (Periplaneta australasiae), and brown cockroaches (Periplaneta australasiae) Cockroach family (Blattidae) such as Blatta orientalis; Yamato termites (Reticulitermes speratus), house termites (Coptotermes formosanus), American Kansai termites (Incisitermes minor), Daikoku termites (Cryptotermes domesticus), and Thai termites (Osantotermes) Neotermes koshunensis, Glyptotermes satsumensis, Naka termites (Glyptotermes nakajimai), Catan termites (Glyptotermes fuscus), Hunting termites (Hodotermopsis sjostedti), Kousui terminus (Guangpsis termes) amamianus), Miyatakei termites (Reticulitermes miyatakei), Japanese terrestrial termites (Reticulitermes kanmonensis), Takasago termites (Nasutitermes takasagoensis), Nitobe termites (Pericapritermes nitobei), Musha termites (Sinocapritermes, termites, etc.

  Fleas (Siphonaptera): Human flea (Pulex irritans) and other plexus genus (Pulex spp.), Cat flea (Ctenocephalides felis), dog flea (Ctenocephalides canis) and other genus Ctenocephalides spp. Xenopsylla cheopis, etc., Xenopsylla spp., Sunnomi (Tunga penetrans), etc., Tunga spp. Nosopsyllus spp.).

  Psocodae: Pediculus spp., Such as head lice (Pediculus humanus capitis); Phylus spp., Such as psyllid (Pthirus pubis); Haematopinus spp .; Bovicola bovis, sheep lice (Bovicola ovis), Bovicola breviceps, etc .; Bovicola spp .; Damalinia forficula, etc .; Damarinia sp. Genus (Linognathus spp.) Such as sheep trunk parasitoid lice (Linognathus ovillus); Solenopotes genus (Solenopotes spp.) Such as Solenopotes capillatus; Cummingsia spp .; Trinoton spp .; Trichodectes spp. Such as Trichodectes canis; Felicola spp., Such as Lami (Felicola subrostratus); Menacanthus spp., Such as chicken whitefly (Menacanthus stramineus); Werneckiella spp., Trogium pulsatorium, etc. (Liposcelis corrodens), Hiratachatate (Liposcelis bostrychophila), Soumenchatate (Liposcelis pearmani), Scarlettaceae (Liposcelis entomophila), and the like (Liposcelidae or Liposcelid).

  Lepidoptera (Thysanura): Lepidoptera (Lepismatidae), such as yamato spot (Ctenolepisma villosa) and sea petrel (Lepisma saccharina).

  Acari: Tetranychus urticae, Tetranychus kanzawai, Tetranychus evansi, Red mites (Panonychus citri), Red spider mites (Panonychus ulmi), Oligonicus sp. (Oligonychus sp. ); Mandarin mite (Aculops pelekassi); Aculus schlechtendali), Aceria diospyri, Aceria tosichella, Eriophyidae such as Sheevtchenkella sp. Family (Tenuipalpidae); e); Ixodidae; for example, Haemaphysalis longicornis, Haemaphysalis flava, Haemaphysalis flava, Haemaphysalis japonica, Haemaphysalis campanulata, and the like genus Haemaphysalis spp. (Dermacentor variabilis), Dermacentor taiwanensis, Rocky Mountain Wood Chick (Dermacentor andersoni), Dermacentor reticulatus (Dermacentor reticulatus) and other genus Dermacentor spp. Killer genus such as black legged tick (Ixodes scapularis), western black tick (Ixodes pacificus), Ixodes holocyclus, Ixodes ricinus and other tick genus (Ixodes spp.), Lone star tic (Amblyomma americanum), gulf coast ticks (Amblyomma maculatum) (Amblyomma spp.), Rhipicephalus microp lus), cattle ticks (Rhipicephalus annulatus), Rhipicephalus ticks (Rhipicephalus sanguineus), Rhipicephalus appendiculatus, Rhipicephalus decoloratus, etc .; Rhipicephalus spp.); Argasidae), Tyrophagus putrescentiae, Tyrophagus similis, etc .; Acaridae; Dermatophagoides farinae, Dermatophagous pters, etc .; (Cheyletus malaccensis), southern house mite (Chelacaropsis moorei), dog mite (Cheyletiella yasguri), and other clawed mites (Cheyletidae); todectes cynotis, genus Choroptes spp., etc .; Psoroptidae; Sarcoptidae); Dermanyssus gallinae; Dermanyssidae; Dermanyssidae; Dermanyssidae; Ornithonyssus sylviarum; Ornithonyssus bacoron; Dermaticidae (Varroidae), such as Dermatophagoids (Varroa jacobsoni), Demodexidae (Demodicidae), such as Dermatophagoides (Demodex canis) and Dermatophagoides (Demodex cati); , Stag beetles (Leptotrombidium scutellare), etc. (Trombiculidae)

Araneae: A spider family (Eutichuridae) such as birch spider (Cheiracanthium japonicum); and a spider family (Theridiidae) such as Latrodectus hasseltii.
Polydesmida: Paradoxosomatidae, such as Oxidus gracilis and Nedyopus tambanus.
Isopoda: Armadillidiidae, such as Armadillidium vulgare.
Chilopoda: Scutigeridae, such as pheasant (Thereuonema hilgendorfi); Scolopendridae, such as Scolopendra subspinipes;
Gastropoda: Limacidae, such as Lime marginatus and Limax flavus; Phyllomycidae, such as slugs (Meghimatium bilineatum); (Ampullariidae); Lymnaeidae (Austropeplea ollula) and the like.

  Nematoda: Aphelenchoididae such as Aphelenchoides besseyi, etc .; Southern nematodes (Pratylenchus coffeae), Pratylenchus brachyurus, and Mugi negusales pula, s. Lentaceae (Pratylenchidae); Java root-knot nematode (Meloidogyne javanica), sweet potato root-knot nematode (Meloidogyne incognita), guava root-knot nematodes (Meloidogyne enterolobii), red-necked root-knot nematode (Meloidogyne hapla) Heteroderidae such as Globodera rostochiensis) and potato white cyst nematode (Globodera pallida); Hoplolimidae such as Rotylenchulus reniformis (Hoplolaimidae); Rubiaceae (Anguinidae); Tylenchulidae (Tylenchulus semipenetrans) and other Tylenchulidae; Longiridae (Vine grape) (Xiphinema index) and the like; Longidoridae; Trichodoridae; Bursaphelophilus xyl Parasita ahelenidae (Parasitaphelenchidae).

  Regarding the harmful arthropods such as harmful insects and harmful mites, harmful molluscs, and harmful nematodes, intra-species variation is not limited. That is, it also includes arthropod pests, molluscs, and nematodes that have decreased sensitivity (also referred to as showing resistance) to specific insecticides, acaricides, molluscicides, and nematicides. It is. Examples of the insecticide, the acaricide, the molluscicide and the nematicide include groups a1 to a26.

Group a1: Acetylcholinesterase inhibitors Group 1A carbamate and group 1B organophosphorus compounds of the class of action by IRAC, such as alanicarb, aldicarb, bendiocarb, benfuracarb, butocarboxy (Butocarboxim), butoxycarboxim (butoxycarboxim), carbaryl (carbaryl: NAC), carbofuran (carbofuran), carbosulfan (carbosulfan), ethiophencarb (ethiofencarb), fenobucarb (fenobucarb: BPMC), formetanate (formetanate), fratiothiocarb ( furathiocarb), isoprocarb (isoprocarb: MIPC), methiocarb (methiocarb), methomil (methomyl), methoxychlor (methoxychlor), metolcarb (metolcarb), oxamyl (oxamyl), pirimicarb (pirimicarb), promecarb (promecarb), propoxur (propoxur: PHC) ), Thiodicarb, thiofanox, triazamate, trimethacarb, xylylcarb (xylylcarb); acephate, azamethiphos, azinphos-ethyl, azinphos-methyl (azinphos-methyl) methyl), cadusafos, chlorethoxyfos, chlorfenvinphos, chlormephos, chlormephos, chlorpyrifos, chlorpyrifos-methyl, chlorpyrifos-methyl, coumaphos, cyanophos: CYAP , Demeton (demeton), demeton-S-methyl (demeton-S-methyl), diazinon (diazinon), dichlorvos (dichlorvos: DDVP), dicrotophos (dicrotophos), dimethoate (dimethoate), dimethylvinphos (dimethylvinphos), disulfoton ( disulfoton), EPN, ethion, ethopro phos), fanflu (famphur), fenamiphos (fenamiphos), fenchlorphos (fenchlorphos), fenitrothion (fenitrothion: MEP), fenthion (fenthion: MPP), phosthiazate (fosthiazate), heptenophos (heptenophos), imiciaphos (imicyafos), Isofenphos, isopropyl-O- (methoxyaminothiophosphoryl) salicylate, isopropyl-O- (methoxyaminothiophosphoryl) salicylate, isoxathion, malathion, malathion, mecarbam, methamidophos, methidathion : DMTP), mevinphos, monocrotophos, nared (naled: BRP), omethoate, omethoate, oxydemeton-methyl, parathion, parathion-methyl, phentoate (phenthoate: PAP), phorate, phosalone, ho Smet (phosmet: PMP), phosphamidon, phoxim, pirimiphos-methyl, profenofos, profenofos, propetamphos, prothiofos, pyraclofos, pyrazophos, pyrazophos (pyridaphenthion), quinalphos (quinalphos), sulfotep (sulfotep), sulprofos (sulprofos), tebupyrimphos (tebupirimfos), temephos (temephos), terbufos (terbufos), tetrachlorvinphos (tetrachlorvinphos), thiometon (thiometon) ), Triazophos, trichlorfon (DEP) and vamidothion.

Group a2: GABAergic chloride channel blocker Group 2A cyclic diene organochlorine and group 2B phenylpyrazole based compounds classified by IRAC, such as chlordane, endosulfan, dieldrin, ethiprole ), Fipronil and flufiprole, pyriprole.

Group a3: Group 3A pyrethroids and group 3B of the class of action by the sodium channel modulator IRAC, such as acrinathrin, allethrin, bifenthrin, kappa-bifenthrin, kappa-bifenthrin, bioallethrin, Bioresmethrin, cycloprothrin, cyclofluthrin, cyfluthrin, beta-cyfluthrin, beta-cyfluthrin, cyhalothrin, gamma-cyhalothrin, gamma-cyhalothrin, lambda-cyhalothrin , Cypermethrin, cypermethrin, alpha-cypermethrin, betacypermethrin (beta-cypermethrin), theta-cypermethrin (theta-cypermethrin), zeta-cypermethrin (zeta-cypermethrin), sigma-cypermethrin (sigma- cypermethrin), cyphenotrin (cyphenot hrin), deltamethrin (deltamethrin), empenthrin (empenthrin), esfenvalerate (esfenvalerate), etofenprox (etofenprox), fenpropatrin (fenpropathrin), fenvalerate (fenvalerate), flucitrinate (flucythrinate), flumethrin (flumethrin) ), Fluvalinate, fluvalinate (tau-fluvalinate), halfenprox (halfenprox), heptafluthrin (heptafluthrin), imiprothrin (imiprothrin), kadesulin (kadethrin), meperfluthrin (meperfluthrin), monfluorothrin ( momfluorothrin), permethrin, phenothrin, prarethrin, pyrethrins, resmethrin, silafluofen, tefluthrin, tefluthrin, kappa-tefluthrin ), Tetramethi Fluthrin (tetramethylfluthrin), tralomethrin (tralomethrin), transfluthrin (transfluthrin), benfluthrin (benfluthrin), flufenprox (flufenoprox), flumethrin (flumethrin), furamethrin (furamethrin), metofluthrin (metofluthrin), profluthrin (proflutrin) (dimefluthrin), a group consisting of DDT.

Group a4: nicotinic acetylcholine receptor competitive modulators Groups of action by the IRAC Group 4A neonicotinoids, 4B nicotine, 4C butenolide, 4D sulfoximine and 4E mesoion, such as acetamiprid, clothianidin, Dinotefuran, imidacloprid, imitecloprid, nitenpyram, thiacloprid, thiamethoxam, flupyradifurone, sulfoxaflor, sulfoxaflor, cycloxapromepyri, cycloxaprimexyl (Dicloromezotiaz) and flupirmine.

Group a5: nicotinic acetylcholine receptor allosteric modulator Group 5 Classification of action by the IRAC.

Group a6: Glutamatergic chloride channel allosteric modulator Group 6 of action classification by IRAC Abamectin system, milbemycin system, for example, abamectin (abamectin), emamectin benzoate (emamectin-benzoate), lepimectin, milbemectin (milbemectin) , Dimadectin (dimadectin), doramectin (doramectin), eprinomectin (eprinomectin), ivermectin (ivermectin), latidectin (latidectin), selamectin (selamectin), milbemycin D (milbemycin D), moxidectin (moxidectin) and nemadectin (nemadectin) .

Group a7: juvenile hormone mimic Group 7A juvenile hormone analogs of action classification by IRAC, Group 7B phenoxycarb and 7C pyriproxyfen, such as hydroprene, kinoprene, methoprene, phenoxycarb ( A group consisting of fenoxycarb) and pyriproxyfen.

Group a8: Group 9 of classifying actions by the string organ TRPV channel modulator IRAC.

Group a9: Microorganism-derived insect midgut endometrial disrupting agent IRAC Classification of action by IRAC Group 11A Bacillus thuringiensis, Group 11B Bacillus sphaericus, for example, Bacillus sphaericus, Bacillus thuringiensis BD # 32 strain (Bacillus thuringiensis strain BD # 32), Bacillus thuringiensis strain AQ52 (Bacillus thuringiensis strain AQ52), Bacillus thuringiensis isawai subsp.ABTS-1857 strain (Bacillus thuringiensis subsp.aizawai strain ABTS-1857), Subsp. Strain HD-1 (Bacillus thuringiensis subsp.kurstaki strain HD-1), Bacillus thuringiensis subsp. Strain BMP123 (Bacillus thuringiensis subsp.kurstaki strain BMP123), Bacillus thuringiensis tenebriosis subsp. thuringiensis subsp.Tenebriosis strain NB176), Bacillus thuringiensis var.israelensis, Bacillus thuringiensis aegipti (Bacillus thuringiensis var.aegypti), Bacillus thuringiensis colmeri var. , Bacillus thuringiensis var.darmstadiensis, Bacillus thuringiensis var.dendrolimus, Bacillus thuringiensis var.・ Thuringiensis japonensis varieties (Bacillus thuringiensis var. Japonensis), Bacillus thuringiensis morisoni subspecies (Bacillus thuringiensis subsp.morrisoni), Bacillus thuringiensis San Diego varieties (Bacillus thuringi) ensis var. san diego), Bacillus thuringiensis subsp.Thuringiensis strain MPPL002, Bacillus thuringiensis 7216 variant (Bacillus thuringiensis var. 7216), Bacillus thuringiensis T36 variant Tac (Bacillus thuringiensis var. Hybrid protein), Cry1C, Cry1F, Cry1Fa2 (modified cry1F), moCry1F (modified Cry1F), Cry1A. 105 (Cry1Ab, Cry1Ac, hybrid protein fused with Cry1F), Cry2Ab2, Cry2Ae, Cry9C, Vip3A, Vip3Aa20), a delta-endotoxin that confers resistance to Coleoptera insects (e.g. Cry3A, mCry3A (modified Cry3A), Cry3B1 , Cry34Ab1, Cry35Ab1), and delta-endotoxins having insecticidal activity against mosquitoes (eg, Cry1A, Cry4A, Cry4B, Cry11A).

Group a10: Oxidative phosphorylation uncoupling agent that disrupts the proton gradient. Group 13 of action classification by IRAC, for example, the group consisting of chlorfenapyr and sulfluramid.

Group a11: Nicotinic acetylcholine receptor channel blocker Group 14 Nereistoxin analogs of action classification by IRAC, such as bensultap, cartap, cartap hydrochloride, thiocyclam, thiocyclam Group consisting of disodium salt (thiosultap-disodium) and thiosultap-monosodium salt.

Group a12: Chitin biosynthesis inhibitor Group 15 benzoyl urea and group 16 buprofezin of action classification by IRAC such as bistrifluron, chlorfluazuron, diflubenzuron, flucycloxuron The group consisting of flucycloxuron, flufenoxuron, hexaflumuron, lufenuron, novalron, noviflumuron, noviflumuron, teflubenzuron, triflumuron and buprofezin.

Group a13: Molting inhibitor Group 17 in the classification of effects by IRAC, for example, the group consisting of cyromazine.

Group a14: molting hormone (ecdysone) receptor agonist A group of diacyl hydrazines classified by the IRAC, such as chromafenozide, halofenozide, methoxyfenozide, and methoxyfenozide, and tebufenozide.

Group a15: voltage-gated sodium channel blocker A group consisting of group 22A oxadiazine and group 22B semicarpazones, such as indoxacarb and metaflumizone, in the class of action by IRAC.

Group a16: Acetyl-CoA carboxylase inhibitor IRAC Group of action 23 Group consisting of tetronic acid, tetramic acid derivatives such as spirodiclofen, spiromesifen and spirotetramat.

Group a17: Ryanodine receptor modulator agent Group 28 of action class by IRAC, such as chlorantraniliprole, cyanantraniliprole, cycloniliprole, flubendiamide, flubendiamide, A group consisting of tetraniliprole, cyhalodiamide, and tetrachlorantraniliprole.

Group a18: String Organ Modulator Agent Group 29 of action classification by IRAC, for example the group consisting of flonicamid.

Group a19: Group 10 of action classification by tick growth inhibitor IRAC, for example, a group consisting of etoxozole, clofentezine, hexythiazox.

Group a20: Group 19 of octopamine receptor agonist IRAC classification of action, for example, the group consisting of amitraz.

Group a21: mitochondrial electron transport system complex IV inhibitor Group 24 of the action classification by IRAC, for example, a group consisting of phosphine.

  Group a22: a group consisting of isoxazoline compounds, for example, afoxolaner, fluralaner, sarolaner, and lotilaner.

Group a23: Mitochondrial ATP synthase inhibitor Group 12 of action classification by IRAC, for example, the group consisting of diafenthiuron.

Group a24: Mitochondrial electron transport system complex III inhibitor Group 20, classified by IRAC, for example, acequinocyl, bifenazate.

Group a25: mitochondrial electron transport system complex I inhibitor (METI)
Group 21 of action classification by IRAC, for example the group consisting of pyridaben, fenpyroximate.

  Group a26: a group consisting of azadiractin and pyridalyl.

  Causes of decreased sensitivity include [1] amino acid substitution of the target protein, [2] decreased target protein, [3] enhanced metabolism, [4] decreased skin permeability, and [5] excretion function by membrane transporters Enhancement. In [1], the target protein may have one or more amino acid substitutions. The metabolic enhancement of [3] means, for example, an increase in the activity of metabolic enzymes (also called detoxifying enzymes) such as cytochrome P450, carboxylesterase, and glutathione S-transferase. . Factors that reduce sensitivity include: [1] amino acid substitution of target protein, [2] reduction of target protein, [3] enhancement of metabolism, [4] decreased skin permeability, and [5] excretion function by membrane transporter May be present alone or in combination.

  Examples of harmful arthropods, harmful molluscs, and harmful nematodes, such as harmful insects and harmful mites, with reduced susceptibility include the following.

Hemiptera with reduced sensitivity to one or more compounds selected from group a2;
Hemiptera with reduced sensitivity to one or more compounds selected from group a4;
Hemiptera with reduced sensitivity to one or more compounds selected from group a8;
Hemiptera with reduced sensitivity to one or more compounds selected from group a12;
One or more compounds selected from group a2, and Hemiptera with reduced sensitivity to one or more compounds selected from group a4;
One or more compounds selected from group a2, and Hemiptera with reduced sensitivity to one or more compounds selected from group a8;
One or more compounds selected from group a2, and Hemiptera with reduced sensitivity to buprofezin belonging to group a12;
One or more compounds selected from group a4, and Hemiptera with reduced sensitivity to one or more compounds selected from group a8;
One or more compounds selected from group a4, and Hemiptera with reduced sensitivity to buprofezin belonging to group a12;
One or more compounds selected from group a8, and Hemiptera with reduced sensitivity to buprofezin belonging to group a12;
One or more compounds selected from group a2, one or more compounds selected from group a4, and Hemiptera with reduced sensitivity to one or more compounds selected from group a8;
One or more compounds selected from group a2, one or more compounds selected from group a4, and a Hemiptera with reduced sensitivity to buprofezin belonging to group a12;
One or more compounds selected from group a2, one or more compounds selected from group a8, and Hemiptera with reduced sensitivity to buprofezin belonging to group a12;
One or more compounds selected from group a4, one or more compounds selected from group a8, and a Hemiptera with reduced sensitivity to buprofezin belonging to group a12;
One or more compounds selected from group a2, one or more compounds selected from group a4, one or more compounds selected from group a8, and a Hemiptera with reduced sensitivity to buprofezin belonging to group a12;
Grasshoppers with reduced sensitivity to one or more compounds selected from group a2;
Grasshoppers with reduced sensitivity to one or more compounds selected from group a4;
Grasshoppers with reduced sensitivity to one or more compounds selected from group a8;
Grasshoppers with reduced sensitivity to one or more compounds selected from group a12;
One or more compounds selected from the group a2, and a planthopper with reduced sensitivity to one or more compounds selected from the group a4;
One or more compounds selected from the group a2, and a planthopper family with reduced sensitivity to pymetrozine belonging to the group a8;
One or more compounds selected from the group a2 and a planthopper whose susceptibility to buprofezin belonging to the group a12 is reduced;
One or more compounds selected from the group a4, and a planthopper family with reduced sensitivity to pymetrozine belonging to the group a8;
One or more compounds selected from the group a4, and a planthopper family with reduced sensitivity to buprofezin belonging to the group a12;
One or more compounds selected from the group a2, one or more compounds selected from the group a4, and a planthopper family with reduced sensitivity to pymetrozine belonging to the group a8;
One or more compounds selected from the group a2, one or more compounds selected from the group a4, and a planthopper whose susceptibility to buprofezin belonging to the group a12 is reduced;
One or more compounds selected from the group a2, pymetrozine belonging to the group a8, and a planthopper family with reduced sensitivity to buprofezin belonging to the group a12;
One or more compounds selected from the group a4, pymetrozine belonging to the group a8, and a planthopper family with reduced sensitivity to buprofezin belonging to the group a12;
One or more compounds selected from the group a2, one or more compounds selected from the group a4, pymetrozine belonging to the group a8, and a planthopper family with reduced sensitivity to buprofezin belonging to the group a12;
Brown planthopper, brown planthopper, or brown planthopper with reduced sensitivity to one or more compounds selected from group a2;
Brown planthopper, brown planthopper, or brown planthopper with reduced sensitivity to one or more compounds selected from group a4;
Brown planthopper, brown planthopper, or brown planthopper with reduced sensitivity to one or more compounds selected from group a8;
Brown planthopper, brown planthopper, or brown planthopper with reduced sensitivity to one or more compounds selected from group a12;
One or more compounds selected from group a2, and a brown planthopper, sage brown planthopper, or brown planthopper with reduced sensitivity to one or more compounds selected from group a4;
One or more compounds selected from group a2, and brown planthoppers, brown planthoppers, or brown planthoppers having reduced sensitivity to pymetrozine belonging to group a8;
One or more compounds selected from group a2, and brown planthoppers, brown planthoppers, or brown planthoppers having reduced sensitivity to buprofezin belonging to group a12;
One or more compounds selected from the group a4, and brown planthoppers, brown planthoppers, or brown planthoppers having reduced sensitivity to pymetrozine belonging to the group a8;
One or more compounds selected from the group a4, and brown planthoppers, brown planthoppers, or brown planthoppers having reduced sensitivity to buprofezin belonging to the group a12;
One or more compounds selected from the group a2, one or more compounds selected from the group a4, and a brown planthopper, a brown planthopper, or a brown planthopper with reduced sensitivity to pymetrozine belonging to the group a8;
One or more compounds selected from the group a2, one or more compounds selected from the group a4, and a brown planthopper, a brown planthopper, or a brown planthopper with reduced sensitivity to buprofezin belonging to the group a12;
One or more compounds selected from group a2, pymetrozine belonging to group a8, and brown planthopper, cedar planthopper, or brown planthopper with reduced sensitivity to buprofezin belonging to group a12;
One or more compounds selected from group a4, pymetrozine belonging to group a8, and brown planthopper, sage brown planthopper, or brown planthopper with reduced sensitivity to buprofezin belonging to group a12;
One or more compounds selected from group a2, one or more compounds selected from group a4, pymetrozine belonging to group a8, and brown planthopper, cedar planthopper, or brown planthopper with reduced sensitivity to buprofezin belonging to group a12;
Aphid family with reduced sensitivity to one or more compounds selected from group a3;
Aphid family with reduced sensitivity to one or more compounds selected from group a8;
One or more compounds selected from the group a3 and aphids having reduced sensitivity to one or more compounds selected from the group a4;
One or more compounds selected from group a3 and aphid family with reduced sensitivity to one or more compounds selected from group a8;
One or more compounds selected from the group a4 and aphids with reduced sensitivity to one or more compounds selected from the group a8;
One or more compounds selected from group a3, one or more compounds selected from group a4, and one or more compounds selected from group a8, wherein the aphid family has reduced sensitivity to one or more compounds;
Peach aphid with reduced sensitivity to one or more compounds selected from group a1;
Cotton aphid or peach aphid with reduced sensitivity to one or more compounds selected from group a3;
Cotton aphid or peach aphid with reduced sensitivity to one or more compounds selected from group a4;
Cotton aphid or peach aphid with reduced sensitivity to one or more compounds selected from group a8;
A cotton aphid or a green peach aphid having reduced sensitivity to one or more compounds selected from group a3 and one or more compounds selected from group a4;
A cotton aphid or a green peach aphid having reduced sensitivity to one or more compounds selected from group a3 and one or more compounds selected from group a8;
A cotton aphid or a green peach aphid having reduced sensitivity to one or more compounds selected from group a4 and one or more compounds selected from group a8;
One or more compounds selected from group a3, one or more compounds selected from group a4, and a cotton aphid or peach peach aphid having reduced sensitivity to one or more compounds selected from group a8; selected from group a3 Tobacco whitefly with reduced sensitivity to one or more compounds;
Tobacco whitefly with reduced sensitivity to one or more compounds selected from group a4;
Peach aphid with reduced sensitivity to one or more compounds selected from group a1;
Cotton aphids having reduced sensitivity to carbamate compounds selected from group a1 and / or organophosphorus compounds selected from group a1;
Reduced susceptibility to malathion, chlorpyrifos, diazinon, fenobcarb, carbofuran, ethiprole, fipronil, flufiprole, etofenprox, dinotefuran, imidacloprid, nitenpyram, sulfoxaflor, thiacloprid, thiamethoxam, pymetrozine, and / or buprofezin;
Cedromorpha with reduced sensitivity to isoprocarb, chlorpyrifos, imidacloprid, and / or buprofezin;
Amrasca biguttula biguttula with reduced sensitivity to imidacloprid, thiamethoxam, acetamiprid, thiacloprid, clothianidin, and / or dinotefuran;
Cotton aphid with reduced sensitivity to pirimicarb and / or an organophosphorus compound selected from the group a1; triazamate, pirimicarb, endosulfan, deltamethrin, lambda cyhalothrin, DDT, and / or peach aphid with reduced sensitivity to imidacloprid;
Lettuce aphid with reduced sensitivity to pirimicarb, mesomil, acephate, dieldrin, and / or endosulfan;
English Grain Aphids with reduced sensitivity to lambda siahalosulin;
Onsin whitefly with reduced sensitivity to one or more compounds selected from group a4, bifenthrin, and / or spiromesifen;
Tobacco whitefly with reduced sensitivity to pirimiphosmethyl, profenophos, endosulfan, fipronil, lambda cyhalothrin, bifenthrin, alpha cypermethrin, cartap, buprofezin, spiromesifen, chlorantraniliprole, diafenthiuron, and / or azadirachtin;
Tangerine lice with reduced sensitivity to chlorpyrifos, bifenthrin, cypermethrin, acetamiprid, imidacloprid, thiamethoxam, nitenpyram, and / or chlorfenapyr;
Brown stink bug with reduced sensitivity to monocrotophos, methamidophos, acephate, endosulfan, beta-cyfluthrin, and / or imidacloprid;
Lepidoptera with reduced sensitivity to one or more compounds selected from group a14;
Lepidoptera with reduced sensitivity to one or more compounds selected from group a15;
Lepidoptera with reduced sensitivity to one or more compounds selected from group a17;
One or more compounds selected from group a14 and lepidoptera having reduced sensitivity to one or more compounds selected from group a17;
Diamondback moth with reduced sensitivity to one or more compounds selected from group a15;
Diamondback moth with reduced sensitivity to one or more compounds selected from group a17;
Cobb beetle with reduced sensitivity to one or more compounds selected from group a14;
Cobb beetle with reduced sensitivity to one or more compounds selected from group a17;
One or more compounds selected from the group a14 and one or more compounds selected from the group a17 having reduced susceptibility to the compound;
Poison ivy with reduced sensitivity to one or more compounds selected from group a3;
Helicoverpa armigera with reduced sensitivity to one or more compounds selected from group a9;
Corn ear worm with reduced sensitivity to one or more compounds selected from group a9;
Chahamaki with reduced sensitivity to one or more compounds selected from group a14;
Chahamaki with reduced sensitivity to one or more compounds selected from group a17;
Anopheles pallidum reduced in sensitivity to one or more compounds selected from group a14; Antelope linoleum reduced in sensitivity to one or more compounds selected from group a17; One or more compounds selected from group a14 , And diminished sensitivity to one or more compounds selected from group a17;
Diamondback moth with reduced sensitivity to one or more compounds selected from group a3;
Tuta absoluta having reduced sensitivity to one or more compounds selected from group a17;
Dictyostelium with reduced sensitivity to endosulfan, fipronil, and / or thiosultap monosodium salt;
European corn borers with reduced sensitivity to deltamethrin and / or lambda cyhalothrin;
A sugar cane borer with reduced sensitivity to the delta-endotoxin Cry1Ab and / or Cry1Ac;
Eggplant fruit borers with reduced sensitivity to profenophos, carbaryl, chlorpyrifos, endosulfan, deltamethrin, and / or fenvalerate;
Profenofos, chlorpyrifos, quinalphos, phoxime, triazophos, mesomil, thiodicarb, endosulfan, fipronil, cypermethrin, deltamethrin, beta-cyfluthrin, spinosad, abamectin, emamectin benzoate, lufenuron, diflubenzuron, methoxyfenozide, and / or susceptibility to indox Spodoptera litura with reduced sensitivity to chlorpyrifos, deltamethrin, cypermethrin, spinosad, abamectin, emamectin benzoate, lufenuron, indoxacarb, and / or methoxyfenozide;
Armyworm with reduced sensitivity to the delta-endotoxins Cry1Ab, Cry1Ac, Cry2Ab2, Cry2Ae, and / or Cry1F;
Poison ivy with reduced sensitivity to sulprofos, profenophos, monocrotophos, parathionmethyl, thiodicarb, mesomil, toxaphen, endosulfan, cypermethrin, deltamethrin, DDT, and / or spinosad;
Helicoverpa armigera with reduced sensitivity to monocrotophos, chlorpyrifos, profenophos, mesomil, thiodicarb, toxaphen, endosulfan, fenvalerate, deltamethrin, cypermethrin, DDT, indoxacarb, and / or chlorantraniliprole;
Corn earworms with reduced sensitivity to parathionmethyl, cypermethrin, endosulfan, and / or DDT;
Codling moss with reduced sensitivity to lambda cyhalothrin, thiacloprid, and / or methoxyfenozide;
European grape wine moss with reduced sensitivity to deltamethrin and / or indoxacarb;
Reduced sensitivity to mesomemil, dieldrin, permethrin, fipronil, spinosad, abamectin, emamectin benzoate, delta-endotoxin Cry1C, lufenuron, indoxacarb, chlorantraniliprole, flubendiamide, and / or diafenthiuron Konaga;
A Hymenoptera with reduced sensitivity to one or more compounds selected from group a2;
A Hymenoptera with reduced sensitivity to one or more compounds selected from group a3;
A Hymenoptera with reduced sensitivity to one or more compounds selected from group a4;
A Hymenoptera with reduced sensitivity to one or more compounds selected from group a9;
A Hymenoptera with reduced sensitivity to one or more compounds selected from group a17;
Thrush with reduced sensitivity to one or more compounds selected from group a3;
Thrips with reduced sensitivity to profenophos, chlorpyrifos, deltamethrin and / or lambda cyhalothrin;
Methiocarb, mesomil, bendiocarb, formethanate, carbofuran, malathion, chlorpyrifos, diazinon, methamidophos, dimethoate, dichlorvos, acephate, metidathion, toxaphene, endosulfan, fipronil, acrinatrine, alpha cypermethrin, bifenthrin, deltamethrin, deltamethrin, deltamethrin Thrips palmi with reduced sensitivity to taufluvalinate, cypermethrin, fenvalerate, cyfluthrin, imidacloprid, spinosad, spinetoram, abamectin, pyriproxyfen, and / or cyantranylprol;
Diptera with reduced sensitivity to one or more compounds selected from group a2;
Diptera with reduced sensitivity to one or more compounds selected from group a3;
Diptera with reduced sensitivity to one or more compounds selected from group a4;
A dipteran with reduced sensitivity to one or more compounds selected from group a9;
A dipteran with reduced sensitivity to one or more compounds selected from group a17;
Tomato leaf fly with reduced sensitivity to permethrin and / or fenvalerate;
Bean bean leaf fly with reduced sensitivity to methamidophos, parathionmethyl, pyrazophos, demeton, chlorpyrifos, triazophos, permethrin, cypermethrin, DDT, spinosad, abamectin, and / or cyromazine;
Coleoptera with reduced sensitivity to one or more compounds selected from group a2;
Coleoptera with reduced sensitivity to one or more compounds selected from group a3;
Coleoptera with reduced sensitivity to one or more compounds selected from group a4;
Coleoptera with reduced sensitivity to one or more compounds selected from group a9;
A Coleoptera with reduced sensitivity to one or more compounds selected from group a17;
One or more compounds selected from group a2 and Coleoptera with reduced sensitivity to one or more compounds selected from group a4;
Chrysomelidae with reduced sensitivity to one or more compounds selected from group a2;
Chrysomelidae with reduced sensitivity to one or more compounds selected from group a3;
Chrysomelidae with reduced sensitivity to one or more compounds selected from group a4;
Chrysomelidae with reduced sensitivity to one or more compounds selected from group a9;
Chrysomelidae with reduced sensitivity to one or more compounds selected from group a17;
One or more compounds selected from group a2 and a leaf beetle having reduced sensitivity to one or more compounds selected from group a4;
A rice beetle with reduced sensitivity to one or more compounds selected from group a2;
A rice beetle with reduced sensitivity to one or more compounds selected from group a4;
One or more compounds selected from group a2 and a rice beetle with reduced sensitivity to one or more compounds selected from group a4;
Diabrotica with reduced sensitivity to one or more compounds selected from group a2;
Diabrotica with reduced sensitivity to one or more compounds selected from group a3;
Diabrotica with reduced sensitivity to one or more compounds selected from group a4;
Diabrotica having reduced sensitivity to one or more compounds selected from group a9;
Diabrotica with reduced sensitivity to one or more compounds selected from group a17;
Western corn rootworm with reduced sensitivity to one or more compounds selected from group a2;
Western corn rootworm with reduced sensitivity to one or more compounds selected from group a3;
Western corn rootworm with reduced sensitivity to one or more compounds selected from group a4;
Western corn rootworm with reduced sensitivity to one or more compounds selected from group a9;
Western corn rootworm with reduced sensitivity to one or more compounds selected from group a17;
Western corn rootworm with reduced sensitivity to one or more compounds selected from group a2;
Western corn rootworm with reduced sensitivity to one or more compounds selected from group a3;
Southern corn rootworm with reduced sensitivity to one or more compounds selected from group a4;
Southern corn rootworm with reduced sensitivity to one or more compounds selected from group a9;
Southern corn rootworm having reduced sensitivity to one or more compounds selected from group a17;
Northern corn rootworm with reduced sensitivity to one or more compounds selected from group a2;
Northern corn rootworm with reduced sensitivity to one or more compounds selected from group a3;
Northern corn rootworm with reduced sensitivity to one or more compounds selected from group a4;
Northern corn rootworm having reduced sensitivity to one or more compounds selected from group a9;
Northern corn rootworm with reduced sensitivity to one or more compounds selected from group a17;
Cucabit beetle with reduced sensitivity to one or more compounds selected from group a2;
Cucabit beetle with reduced sensitivity to one or more compounds selected from group a3;
Cucabit beetle with reduced sensitivity to one or more compounds selected from group a4;
Cucabit beetle with reduced sensitivity to one or more compounds selected from group a9;
Cucabit beetle with reduced sensitivity to one or more compounds selected from group a17;
Colorado potato beetle with reduced sensitivity to one or more compounds selected from group a2;
Colorado potato beetle with reduced sensitivity to one or more compounds selected from group a3;
Colorado potato beetle with reduced sensitivity to one or more compounds selected from group a4;
Colorado potato beetle with reduced sensitivity to one or more compounds selected from group a11;
Colorado potato beetle with reduced sensitivity to one or more compounds selected from group a17;
A flea beetle with reduced sensitivity to one or more compounds selected from group a3;
A flea beetle with reduced sensitivity to one or more compounds selected from group a4;
A flea beetle with reduced sensitivity to one or more compounds selected from group a17;
Cabbage free beetle with reduced sensitivity to one or more compounds selected from group a3;
Cabbage free beetle with reduced sensitivity to one or more compounds selected from group a4;
Cabbage free beetle with reduced sensitivity to one or more compounds selected from group a17;
Western black free beetle with reduced sensitivity to one or more compounds selected from group a3;
Western black free beetle with reduced sensitivity to one or more compounds selected from group a4;
Western black free beetle with reduced sensitivity to one or more compounds selected from group a17;
Cabbage stem free beetle with reduced sensitivity to one or more compounds selected from group a3;
Cabbage stem free beetle with reduced sensitivity to one or more compounds selected from group a4;
Cabbage stem free beetle with reduced sensitivity to one or more compounds selected from group a17;
A hop-free beetle having reduced sensitivity to one or more compounds selected from group a3;
Hop-free beetle with reduced sensitivity to one or more compounds selected from group a4;
Hop-free beetle with reduced sensitivity to one or more compounds selected from group a17;
Weevil with reduced sensitivity to one or more compounds selected from group a2;
Weevil with reduced sensitivity to one or more compounds selected from group a4;
One or more compounds selected from group a2 and a weevil family with reduced sensitivity to one or more compounds selected from group a4;
A rice weevil with reduced sensitivity to one or more compounds selected from group a2;
A rice weevil with reduced sensitivity to one or more compounds selected from group a4;
One or more compounds selected from group a2 and a rice weevil with reduced sensitivity to one or more compounds selected from group a4;
Click beetles with reduced sensitivity to one or more compounds selected from group a2;
Click beetles with reduced sensitivity to one or more compounds selected from group a3;
Click beetles with reduced sensitivity to one or more compounds selected from group a4;
Okinawa cricket with reduced sensitivity to one or more compounds selected from group a2;
Okinawa cricket with reduced sensitivity to one or more compounds selected from group a3;
Okinawa cricket with reduced sensitivity to one or more compounds selected from group a4;
A firefly with reduced sensitivity to one or more compounds selected from group a2;
A firefly that has reduced sensitivity to one or more compounds selected from group a3;
A firefly that has reduced sensitivity to one or more compounds selected from group a4;
Crimson beetle with reduced sensitivity to one or more compounds selected from group a2;
Crimson beetle with reduced sensitivity to one or more compounds selected from group a3;
Crimson beetle with reduced sensitivity to one or more compounds selected from group a4;
Acropora with reduced sensitivity to one or more compounds selected from group a2;
Acropora with reduced sensitivity to one or more compounds selected from group a3;
Acropora with reduced sensitivity to one or more compounds selected from group a4;
A genus Conoderus having reduced sensitivity to one or more compounds selected from group a2;
A genus Conoderus having reduced sensitivity to one or more compounds selected from group a3;
A genus Conoderus having reduced sensitivity to one or more compounds selected from group a4;
Ctenicella with reduced sensitivity to one or more compounds selected from group a2;
Ctenicella with reduced sensitivity to one or more compounds selected from group a3;
Ctenicella with reduced sensitivity to one or more compounds selected from group a4;
Limonius with reduced sensitivity to one or more compounds selected from group a2;
Limonius with reduced sensitivity to one or more compounds selected from group a3;
Limonius with reduced sensitivity to one or more compounds selected from group a4;
Aeols with reduced sensitivity to one or more compounds selected from group a2;
Aeols with reduced sensitivity to one or more compounds selected from group a3;
Aeols with reduced sensitivity to one or more compounds selected from group a4;
Cabbage stem-free beetle with reduced sensitivity to lambda cyhalothrin;
Colorado potato beetle with reduced sensitivity to carbosulfan, carbofuran, hosalon, chlorpyrifos, azinphosmethyl, cyhalothrin, lambda cyhalothrin, deltamethrin, permethrin, imidacloprid, dinotefuran, clothianidin, thiacloprid, thiamethoxam, and / or nitenpyram;
Blossom beetle with reduced sensitivity to hosalon, lambda cyhalothrin, cypermethrin, alpha cypermethrin, zetacypermethrin, bifenthrin, beta-cyfluthrin, deltamethrin, esfenvalerate, taufulvalinate, and / or acetamiprid;
Mites having reduced sensitivity to one or more compounds selected from the group a2;
Mites having reduced sensitivity to one or more compounds selected from the group a3;
Mites with reduced sensitivity to one or more compounds selected from group a4;
Mites having reduced sensitivity to one or more compounds selected from group a9;
Mites having reduced sensitivity to one or more compounds selected from the group a17;
A spider mite with reduced sensitivity to one or more compounds selected from group a19, bifenthrin, abamectin, milbemectin, acequinosyl and / or bifenacet;
Apple spider mite with reduced sensitivity to fenpropatrin, spirodiclofen, clofentezin, hexthiazox, pyridaben, and / or fenpyroximate;
Bed bugs with reduced sensitivity to one or more compounds selected from group a1;
Bed bugs with reduced sensitivity to one or more compounds selected from group a2;
Bed bugs with reduced sensitivity to one or more compounds selected from group a3;
Bed bugs with reduced sensitivity to one or more compounds selected from group a4;
Bed bugs with reduced sensitivity to one or more compounds selected from group a5;
Bed bugs with reduced sensitivity to one or more compounds selected from group a10;
Bendiocarb, diazinon, dichlorvos, fenitrothion, fenobcarb, malathion, propoxur, dieldrin, fipronil, arrestrin, bifenthrin, cyfluthrin, beta-cyfluthrin, lambda cyhalothrin, cypermethrin, alpha cypermethrin, deltamethrin, esfenvalerate, ethfenvalerate Bed bugs with reduced sensitivity to Prox, permethrin, phenothrin, pyrethrin, tetramethrin, DDT, acetamiprid, dinotefuran, imidacloprid, thiamethoxam, spinosad, and / or chlorfenapyr;
Netite lice with reduced sensitivity to one or more compounds selected from group a1;
Netite lice with reduced sensitivity to one or more compounds selected from group a2;
Netite lice with reduced sensitivity to one or more compounds selected from group a3;
Netite lice with reduced sensitivity to one or more compounds selected from group a4;
Netite lice with reduced sensitivity to one or more compounds selected from group a10;
Bendiocarb, diazinon, fenitrothion, fenobcarb, malathion, propoxur, dieldrin, fipronil, arelesulin, bifenthrin, cyfluthrin, lambda cyhalothrin, cypermethrin, alpha cypermethrin, deltamethrin, esfenvalerate, etfenprox, permethrin, DDT Netite whitefly with reduced sensitivity to imidacloprid and / or chlorfenapyr;
Housefly having reduced sensitivity to one or more compounds selected from group a1;
Housefly having reduced sensitivity to one or more compounds selected from group a2;
Housefly having reduced sensitivity to one or more compounds selected from group a3;
Housefly having reduced sensitivity to one or more compounds selected from group a4;
Housefly having reduced sensitivity to one or more compounds selected from group a5;
Housefly having reduced sensitivity to one or more compounds selected from group a6;
Housefly having reduced sensitivity to one or more compounds selected from group a7;
Housefly having reduced sensitivity to one or more compounds selected from group a11;
Housefly having reduced sensitivity to one or more compounds selected from group a12;
Housefly having reduced sensitivity to one or more compounds selected from group a13;
Housefly having reduced sensitivity to one or more compounds selected from group a14;
Housefly having reduced sensitivity to one or more compounds selected from group a15;
Azamethiphos, azinphos-methyl, chlorpyrifos, chlorpyrifos-methyl, diazinon, dichlorvos, dimethoate, fenchlorphos, fenitrothion, mesomil, methoxychlor, nared, parathion-methyl, phoxime, propenophos, propoxur, tetrachlorbinphos, triazophos, trichlorphanesulfon, dildofrinil, endorphinil , Bifenthrin, cyfluthrin, beta-cyfluthrin, lambda cyhalothrin, cypermethrin, betacypermethrin, cyphenothrin, deltamethrin, esfenvalerate, phenothrin, pyrethrin, resmethrin, DDT, acetamiprid, dinotefuran, imidacloprithine, quintampinoate Abamectin, Emamecti Benzoate, methoprene, pyriproxyfen, cartap, diflubenzuron, lufenuron, triflumuron, cyromazine, methoxyfenozide, and / or reduced houseflies susceptibility to indoxacarb;
Simulium damnosum with reduced sensitivity to one or more compounds selected from group a1;
Simulium damnosum with reduced sensitivity to one or more compounds selected from group a3;
Culex pipiens reduced in sensitivity to one or more compounds selected from group a2;
Culex pipiens reduced in sensitivity to one or more compounds selected from group a3;
Culex pipiens with reduced sensitivity to bifenthrin, beta-cyfluthrin, lambda cyhalothrin, cypermethrin, deltamethrin, permethrin, and / or resmethrin;
Culex pipiens reduced in sensitivity to one or more compounds selected from group a3;
Culex pipiens with reduced sensitivity to deltamethrin, etofenprox, permethrin, and / or phenothrin;
Aedes domestica with reduced sensitivity to one or more compounds selected from group a1;
Aedes domestica with reduced sensitivity to one or more compounds selected from group a3;
Aedes domestica with reduced sensitivity to temefos, bifenthrin, beta-cyfluthrin, lambda cyhalothrin, cypermethrin, deltamethrin, permethrin, and / or resmethrin;
Aedes aegypti having reduced sensitivity to one or more compounds selected from the group a1;
Aedes aegypti having reduced sensitivity to one or more compounds selected from group a3;
Aedes aegypti having reduced sensitivity to one or more compounds selected from the group a7;
Aedes aegypti having reduced sensitivity to one or more compounds selected from group a9;
Chlorpyrifos, dichlorvos, fenitrothion, fenthion, malathion, pirimiphosmethyl, propoxur, temefos, arelesulin, bifenthrin, cyfluthrin, lambda cyhalothrin, cypermethrin, alpha cypermethrin, deltamethrin, etofenprox, permethrin, phenothrin or DDT, and / or DDT, Aedes aegypti with reduced susceptibility;
Aedes aegypti with reduced sensitivity to delta-endotoxins Cry4A, Cry4B;
Gambier anopheles with reduced sensitivity to one or more compounds selected from group a1;
Gambier anopheles with reduced sensitivity to one or more compounds selected from group a2;
Gambier anopheles with reduced sensitivity to one or more compounds selected from group a3;
Gambiae anemone with reduced sensitivity to bendiocarb, fenitrothion, pirimiphosmethyl, dieldrin, lambda cyhalothrin, deltamethrin, permethrin, and / or DDT;
Anopheles coluzzii with reduced sensitivity to one or more compounds selected from group a1;
Anopheles coluzzii with reduced sensitivity to one or more compounds selected from group a2;
Anopheles coluzzii with reduced sensitivity to one or more compounds selected from group a3;
Anopheles coluzzii with reduced sensitivity to bendiocarb, fenitrothion, dieldrin, lambda cyhalothrin, deltamethrin, permethrin, and / or DDT;
Anopheles arabiensis with reduced sensitivity to one or more compounds selected from group a1;
Anopheles arabiensis with reduced sensitivity to one or more compounds selected from group a2;
Anopheles arabiensis with reduced sensitivity to one or more compounds selected from group a3;
Anopheles arabiensis with reduced sensitivity to bendiocarb, malathion, dieldrin, lambda cyhalothrin, deltamethrin, permethrin, and / or DDT;
Anopheles funestus with reduced sensitivity to one or more compounds selected from group a2;
Anopheles funestus with reduced sensitivity to one or more compounds selected from group a3;
Anopheles funestus with reduced sensitivity to dieldrin, lambda cyhalothrin, deltamethrin, permethrin, and / or DDT;
Dictyostelium with reduced sensitivity to one or more compounds selected from group a1;
Dictyostelium with reduced sensitivity to one or more compounds selected from group a3;
Dictyostelium with reduced sensitivity to one or more compounds selected from group a5;
Dictyostelium having reduced sensitivity to one or more compounds selected from group a21;
Carbaryl, chlorpyrifos, chlorpyrifosmethyl, cyanophos, diazinon, dichlorvos, fenitrothion, malathion, foxime, pirimiphosmethyl, promecarb, propoxur, temefos, tetrachlorvinphos, bioresmethrin, cyfluthrin, cyhalothrin, cypermethrin, deltamethrin, permethrin, permethrin, permethrin, permethrin Scutellaria with reduced sensitivity to, spinosad, and / or phosphine;
German cockroaches having reduced sensitivity to one or more compounds selected from group a1;
German cockroaches having reduced sensitivity to one or more compounds selected from group a2;
German cockroaches having reduced sensitivity to one or more compounds selected from group a3;
German cockroaches having reduced sensitivity to one or more compounds selected from group a4;
German cockroaches having reduced sensitivity to one or more compounds selected from group a6;
German cockroaches with reduced sensitivity to chlorpyrifos, malathion, propoxur, fipronil, beta-cyfluthrin, cypermethrin, deltamethrin, permethrin, pyrethrin, DDT, imidacloprid, and / or abamectin;
A cat flea with reduced sensitivity to one or more compounds selected from group a1;
A cat flea with reduced sensitivity to one or more compounds selected from group a2;
A cat flea with reduced sensitivity to one or more compounds selected from group a3;
A cat flea with reduced sensitivity to one or more compounds selected from group a4;
A cat flea with reduced sensitivity to one or more compounds selected from group a5;
Reduced sensitivity to bendiocarb, carbaryl, chlorfenvinphos, chlorpyrifos, diazinon, fenthion, isofenphos, propethamphos, propoxur, malathion, fipronil, cyfluthrin, cypermethrin, fluvalinate, permethrin, pyrethrin, imidacloprid, and / or spinosad Cat flea;
American black mite with reduced sensitivity to one or more compounds selected from group a3;
American golden ticks with reduced susceptibility to DDT;
Ox tick with reduced sensitivity to one or more compounds selected from group a1;
Ox tick with reduced sensitivity to one or more compounds selected from group a2;
Ox tick with reduced sensitivity to one or more compounds selected from group a3;
Ox tick with reduced sensitivity to one or more compounds selected from group a6;
Ox tick with reduced sensitivity to one or more compounds selected from group a20;
Ox tick with reduced susceptibility to carbaryl, chlorpyrifos, coumaphos, fipronil, pyriprole, cypermethrin, deltamethrin, flumethrin, permethrin, ivermectin, and / or amitraz;
Rhipicephalus sanguineus having reduced sensitivity to one or more compounds selected from group a1;
Rhipicephalus sanguineus having reduced sensitivity to one or more compounds selected from group a3;
A tick, which is less sensitive to one or more compounds selected from group a20;
A tick with reduced sensitivity to permethrin and / or amitraz;

  Examples of harmful arthropods, harmful molluscs, and harmful nematodes such as harmful insects and harmful mites whose sensitivity has been reduced by amino acid substitution of the target protein include the following.

Cotton aphids having an amino acid substitution of R81T in the β subunit of the nicotinic acetylcholine receptor;
Peach aphid having an R81T amino acid substitution in the β subunit of the nicotinic acetylcholine receptor;
Diamondback moth with G4946E amino acid substitution at ryanodine receptor;
Conaga having an amino acid substitution of F1845Y or V1848I in the sodium channel;
Cedilopine with A2'N amino acid substitution in GABAergic chloride channel;
Cotton aphids having S431F and / or A302S amino acid substitutions in acetylcholinesterase;
Tobacco whitefly having an L925I and / or T929V amino acid substitution in a voltage-gated sodium channel;
Peach aphids having L1014F, M918T, and / or TL932F amino acid substitutions in voltage-gated sodium channels;
Peach aphids having A302S and / or A302G amino acid substitutions in the GABAergic chloride channel;
Citrus thrips having L1014F and / or M918T amino acid substitutions in voltage-gated sodium channels;
A Thrips palmi with a G275E amino acid substitution in the α6 subunit of the nicotinic acetylcholine receptor;
Corn earworms having L1029H, V421M, V421A, V421G and / or I951V amino acid substitutions in voltage-gated sodium channels;
Physcomitrella patens with L1029H, D1561V, E1565G, and / or V421M amino acid substitutions in voltage-gated sodium channels;
Colorado potato beetle having an amino acid substitution of R30K, S291G, and / or I392T in acetylcholinesterase;
Colorado potato beetle having an amino acid substitution of L1014F in a voltage-gated sodium channel;
Cedar planthopper with S298P amino acid substitution in acetylcholinesterase type 1;
A spider mite with an amino acid substitution of G323D in the GluCl1 subunit of the glutamate receptor;
A spider mite with an amino acid substitution of G326E in the GluCl3 subunit of the glutamate receptor;
Thrips with M918T, M918L, T929I, V1010A, and / or L1014F amino acid substitutions in voltage-gated sodium channels;
Whiteflies with L925I and / or T929I amino acid substitutions in voltage-gated sodium channels;
Tuta absoluta having G4903V, G4903E, I4746T, and / or I4746M amino acid substitutions in the ryanodine receptor;
Brown planthopper with A301S amino acid substitution in GABAergic chloride channel;
Brown planthopper having an amino acid substitution of Y151S in the α1 and α3 subunits of the nicotinic acetylcholine receptor;
European corn borer with L1014F amino acid substitution in voltage-gated sodium channel;
Apple spider mite with F1538I amino acid substitution in voltage-gated sodium channel;
Cabbage stem free beetle with L1014F amino acid substitution in voltage-gated sodium channel;
English-grain-aid having an amino acid substitution of L1014F in the voltage-gated sodium channel;
Diamondback moth having A282S, A282G, and / or A302S amino acid substitutions in a GABAergic chloride channel;
Konaga having M918I, T929I, and / or L1014F amino acid substitutions in voltage-gated sodium channels;
Bed bugs with V419L, L925I, and / or I936F amino acid substitutions in the α subunit of voltage-gated sodium channels;
Housefly having an amino acid substitution of V180L, V260L, G262A, G262V, G342A, G342V, G365A, F327Y, F407Y, and / or G445A in acetylcholinesterase;
Housefly having M918T, L1014F and / or L1014H amino acid substitutions in the α subunit of the voltage-gated sodium channel;
Housefly having A302S amino acid substitution in GABAergic chloride channel;
Culex pipiens with L1014F and / or L1014S amino acid substitutions in voltage-gated sodium channels;
Culex pipiens with A302S amino acid substitutions in the GABAergic chloride channel;
Culex pipiens with L1014F and / or L1014S amino acid substitutions in voltage-gated sodium channels;
Aedes mosquitoes having L1014F and / or L1014S amino acid substitutions in voltage-gated sodium channels;
Aedes domestica having an amino acid substitution of G119S in acetylcholinesterase;
Aedes aegypti with an amino acid substitution of V410L, G923V, L982W, S989P, I1011M, I1011V, V1016I, V1016G, T1520I, F1534C, and / or D1763Y in the voltage-gated sodium channel;
Gambier anopheles having L1014S and / or N1575Y amino acid substitutions in voltage-gated sodium channels;
Gambiae anemone having an amino acid substitution of G119S in acetylcholinesterase;
Anopheles coluzzii with L1014F and / or N1575Y amino acid substitutions in voltage-gated sodium channels;
Anopheles arabiensis with L1014F amino acid substitution in voltage-gated sodium channel;
Anopheles funestus with A296S, V327I amino acid substitutions in the GABAergic chloride channel;
Acerium japonicus with A302S amino acid substitution in GABAergic chloride channel;
German cockroaches having D58G, E434K, C764R, L933F, and / or P1880L amino acid substitutions in voltage-gated sodium channels;
German cockroach with A302S amino acid substitution in GABAergic chloride channel;
Cat flea having T929V and / or L1014F amino acid substitutions in voltage-gated sodium channels;
Cat flea having an A302S amino acid substitution in a GABAergic chloride channel;
A bovine tick having a C190A and / or F1550I amino acid substitution in a voltage-gated sodium channel.

  Examples of harmful arthropods, harmful molluscs, and harmful nematodes, such as harmful insects and harmful mites, whose susceptibility has decreased due to the decrease in the target protein, include the following.

  Housefly with reduced expression of α2 subunit of nicotinic acetylcholine receptor.

  Factors that increase the activity of metabolic enzymes include, for example, overexpression of metabolic enzyme genes (also referred to as quantitative mutations) and improvement in affinity for drugs by amino acid substitution of metabolic enzymes (also referred to as qualitative mutations). One or more factors that increase the activity of these metabolic enzymes may be present.

  Examples of harmful arthropods, harmful molluscs, and harmful nematodes, such as harmful insects and harmful mites, whose metabolic enzyme activity is increased due to overexpression of the metabolic enzyme gene, include the following.

Brown planthopper overexpressing CYP6ER1 (one of the cytochrome P450 genes);
Amrasca biguttula biguttula overexpressing glutathione-S-transferase gene;
Cotton aphid overexpressing cytochrome P450 monooxygenase gene;
Tobacco whitefly overexpressed with CYP6CM1 (one of the cytochrome P450-dependent monooxygenase genes);
Tobacco whitefly overexpressing cytochrome P450-dependent monoxygenase gene;
Physcomitrella overexpressed with a carboxylesterase gene and / or a microsomal-O-demethylase gene;
Codling moss in which glutathion-S-transferase gene and / or cytochrome P450 monooxygenase gene is overexpressed;
Sugar cane borers with reduced expression of three aminopeptidases N genes (DsAPN1, DsAPN2, and DsAPN3) and / or DsCAD1 (one of the cadherin genes);
Lepidoptera maggot with overexpressed cytochrome P450 gene;
Blossom beetle with overexpressed cytochrome P450 gene;
Peach aphid overexpressed by CYP6CY3 (one of the cytochrome P450 genes);
Peach aphid overexpressing the gene for E4, which is one of carboxylesterases, and / or the FE4 gene, which is one of carboxylesterases;
Lettuce aphid with overexpressed esterase gene;
lettuce aphid with glutathione S-transferases gene overexpression;
Brown stink bug overexpressed esterase gene;
a brown sting bug in which the gene for EST-2, one of cholinesterases, and / or the gene for EST-4, one of cholinesterases, is overexpressed;
Citrus thrips overexpressed with the esterase gene;
Citrus thrips overexpressed with cytochrome P450 monooxygenase gene;
Thrips palmi Karny with overexpressed glutathione S-transferases gene;
Helicoverpa armigera expressing CYP337B3 (one of the cytochrome P450 genes);
Helicoverpa armigera overexpressed with cytochrome P450 monooxygenases gene;
Helicoverpa armigera overexpressing glutathione S-transferases gene;
Helicoverpa armigera overexpressing the esterase gene;
Physcomitrella patens with overexpressed glutathione-S-transferase gene;
False tobacco moth with overexpressed esterase gene;
False tobacco moth with overexpressed cytochrome P450 gene;
Colorado potato beetle overexpressing glutathione-S-transferase gene;
Colorado potato beetle with overexpressed esterase gene;
Colorado potato beetle with overexpressed cytochrome P450 gene;
A spider mite overexpressed TuGSTd14 (one of the glutathione-S-transferase genes);
Onyx whitefly overexpressed by CYP6CM1 (one of the cytochrome P450 genes);
Amberjack mushroom with overexpressed cytochrome P450 gene;
Brown planthopper with reduced expression of CYP6AY1 (one of the cytochrome P450 genes);
brown planthopper with overexpressed carboxylesterases gene;
Brown planthopper with overexpressed gene of Nl-EST1, one of carboxylesterases;
Brown planthopper overexpressed with CYP6ER1, CYP6AY1, and / or CYP6FU1 (one of the cytochrome P450 genes);
European corn borer overexpressed cytochrome P450 monooxygenase gene;
European corn borer overexpressed glutathion-S-transferase gene;
Apple spider mite overexpressed with cytochrome P450-dependent monoxygenase gene;
Cabbage stem-free beetle with overexpressed cytochrome P450 gene;
Bed bugs overexpressing CYP397A1, CYP398A1, CYP6DN1, CYP4CM1, and / or CYP400A1 (all of which are one of the cytochrome P450 genes);
Bed bugs overexpressing CE3959 and / or CE21331 (both of which are carboxylesterases genes);
Bed bugs overexpressing S1 (one of the glutathione-S-transferase genes);
House flies overexpressed with CYP6A1, CYP6A5v1, CYP6A5v2, CYP6A36, CYP6A40, CYP6D1, CYP6D1v1, CYP6D3, CYP6D8, CYP6G2, and / or CYP6G4 (all cytochrome P450 genes);
Aedes mosquito overexpressed with CYP9M10, CYP6AA7 and / or CYP4H34 (all of them are cytochrome P450 genes);
Aedes aegypti with overexpressed esterase gene;
Aedes aegypti with overexpressed glutathione-S-transferase gene;
Aedes aegypti overexpressed CYP4D24, CYP6BB2, CYP6F3, CYP6M11, CYP6N12, and / or CYP9M6 (all are one of the cytochrome P450 genes);
Aedes aegypti with overexpressed carboxylesterase gene;
Gambiae anopheles overexpressed CYP4P16, CYP4P17, CYP6P3, CYP6Z1, CYP12F1, and / or CYP325A3 (all are one of the cytochrome P450 genes);
Gambier anopheles overexpressed GSTE2 (one of the glutathione-S-transferase genes);
Gambier anopheles overexpressed PX13A and / or PX13B (both of which are peroxidase genes);
Gambier anopheles overexpressed the esterase gene;
Anopheles arabiensis overexpressed by CYP6P4 (a type of cytochrome P450 gene);
Anopheles arabiensis overexpressing the carboxylesterase gene;
Anopheles arabiensis overexpressed beta-esterases gene;
Anopheles funestus overexpressed with CYP6P4 and / or CYP6P9 (both are cytochrome P450 genes);
CYP6BQ9 (a type of cytochrome P450 gene) overexpressed in P. japonicum;
Gluconium spp. overexpressed with glutathione-S-transferase gene;
Epsilon (a species of the glutathione-S-transferase gene) overexpressed E.
German cockroach overexpressing CYP4G19 (a type of cytochrome P450 gene).

  Examples of the harmful insects, harmful arthropods such as harmful mites, harmful molluscs and harmful nematodes whose metabolic enzyme activity is increased by improving the affinity with the drug by amino acid substitution of the metabolic enzyme include the following. .

Brown planthopper with CYP6ER1vA (a variant of CYP6ER1) with amino acid substitutions of T318S, A375Δ and A376G;
Brown planthopper with CYP6ER1vB (a variant of CYP6ER1) having T318S and A377Δ amino acid substitutions;
A housefly having a carboxyesterase having an amino acid substitution of W251L and / or W251S;
Congenitomodoki having dihydrolipoamide dehydrogenase having an amino acid substitution of P45S and / or G131S.

  Pest insects having a plurality of factors for increasing the activity of metabolic enzymes, harmful arthropods such as harmful mites, harmful molluscs and harmful nematodes, for example, in addition to overexpression of CYP6ER1, by having CYP6ER1vA and CYP6ER1vB Brown planthoppers with reduced sensitivity to imidacloprid.

  Examples of harmful arthropods, harmful molluscs, and harmful nematodes, such as harmful insects, harmful mites, etc., whose susceptibility has decreased due to a decrease in skin permeability include the following.

Helicoverpa armigera with reduced sensitivity to pyrethroids (eg, cypermethrin, esfenvalerate, etc.) due to reduced cuticular penetration of the drug in the cuticle;
Bed bugs with reduced sensitivity to pyrethroids (such as beta-cyfluthrin) due to overexpression of C2, C10, and / or C13 (all of one of the putative epidermal protein genes).

  Examples of harmful arthropods, harmful molluscs, and harmful nematodes, such as harmful insects and harmful mites, whose susceptibility has been reduced due to enhancement of the excretory function by the membrane transporter, include the following.

  Bed bugs with ABC transporter genes Abc8, Abc9, Abc10 and / or Abc11 overexpressed.

  The compositions of the present invention can also be used to protect plants from plant diseases caused by insect-borne viruses or bacteria.

  Examples of insect-borne viruses include the following.

  Rice tungro spherical virus, Rice tungro bacilliform virus, Rice grassy stunt virus, Rice ragged stunt virus, Rice stripe virus Rice stripe virus), Rice black streaked dwarf virus, Southern rice black-streaked dwarf virus, Rice gall dwarf virus, Rice hojaw blanca virus), Rice yellow stunt virus, Rice yellow mottle virus, Rice dwarf virus, Rice cereal mosaic virus (Northern cereal mosaic virus), Barley yellow dwarf virus , Barley mild mosaic virus, Barley yellow dwarf virus-PAV, Cereal yellow dwarf virus-RPS , Wheat yellow leaf virus, Oat sterile dwarf virus, Wheat streak mosaic virus, Maize dwarf mosaic virus, Maize stripe virus, Maize chlorotic mottle virus, Maize chlorotic dwarf virus, Maize rayado fino virus , Sugarcane mosaic virus, Fiji disease virus, Sugarcane yellow leaf virus, soybean mild mosaic virus, soybean necrotic stunt virus, soybean dwarf virus (Soybean dwarf) virus), Milk vetch dwarf virus, Soy bean mosaic virus, Alfalfa mosaic virus, Bean yellow mosaic virus, Bean mosaic virus ), Southern bean mosaic vi rus), peanut stunt virus, Broad bean wilt virus 1, Broad bean wilt virus 2, Broad bean necrosis virus , Broad bean yellow vein virus, Clover yellow vein virus, Peanut mottle virus, Tobacco streak virus, Bean pod mottle virus, Cowpea chlorotic mottle virus, Mung bean yellow mosaic virus, Soybean crinkle leaf virus, Tomato chlorosis virus, Tomato spotted wilt virus, Tomato yellow leaf curl virus ), Tomato aspermy virus, tomato infectious chlorosis virus, potato cigar Ruth (Potato leafroll virus), potato Y virus (Potato virus Y), melon yellow spot virus (Melon yellow spot virus), melon necrotic spot virus (Melon necrotic spot virus), watermelon mosaic virus (Watermelon mosaic virus), Cucumber mosaic virus, Zucchini yellow mosaic virus, Turnip mosaic virus, Turnip yellow mosaic virus, Turnip yellow mosaic virus, Cauliflower mosaic virus, Lettuce mosaic virus, Celery mosaic virus, Beet mosaic virus, Cucurbit chlorotic yellows virus, Capsicum chlorosis virus , Beet pseudo yellows virus, Leek yellow Leak yellow stripe virus, Onion yellow dwarf virus, Sweet potato feathery mottle virus, Sweet potato shukuyo mosaic virus, Strawberry mottle virus virus), Strawberry mild yellow edge virus, Strawberry pseudo mild yellow edge virus, Strawberry crinkle virus, Strawberry vein banding virus ), Plum pox virus, chrysanthemum stem necrosis virus, impatiens necrotic spot virus, Iris yellow spot virus, lily microspot virus (Lily mottle virus), Lily latent virus (Lily symptomless virus), -Menu lip mosaic virus (Tulip mosaic virus) and the like.

  Examples of insect-borne bacteria include the following.

  Rice yellow dwarf phytoplasma (Candidatus Phytoplasma oryzae), Candidatus Phytoplasma asteris, Maize bushy stunt phytoplasma, citrus greening fungus Asian type (Candidatus Liberbacter asiaticus), citrus greening disease African type (Candidatus Liberbacter africanus) Type (Candidatus Liberbacter americanus), Pierce's disease (Xylella fastidiosa) and the like.

  The composition of the present invention also has a food-damaging effect, a repellent effect, an egg-laying inhibitory effect, an infertility effect, a next-generation production inhibitory effect, a mating behavior inhibitory effect, a molting inhibitory effect, and an emergence inhibitory effect. As a result, the crop can be protected from damage by harmful arthropods such as harmful insects and harmful mites, harmful molluscs, and harmful nematodes.

  ADVANTAGE OF THE INVENTION According to the composition and the method of the present invention, plant diseases caused by phytopathogenic microorganisms such as fungi, oomycete, Phytomyxea, and bacteria can be controlled. Fungi include, for example, Ascomycota, Basidiomycota, Blasocladiomycota, Chytridiomycota, Mucoromycota, and Olpidiomycota. Specifically, the following are mentioned, for example. The names in parentheses indicate the scientific names of the phytopathogenic microorganisms that cause each disease.

Diseases of rice: blast (Pyricularia oryzae), sesame leaf blight (Cochliobolus miyabeanus), sheath blight (Rhizoctonia solani), stupid seedling (Gibberella fujikuroi), yellow dwarf (Sclerophthora macrospora), blast and blight Ear blight (Epicoccum nigrum), seedling blight (Trichoderma viride, Rhizopus oryzae);
Wheat diseases: powdery mildew (Blumeria graminis), red mold (Fusarium graminearum, Fusarium avenaceum, Fusarium culmorum, Microdochium nivale), yellow rust (Puccinia striiformis), black rust (Puccinia graminis), red rust dita (Puccinia red) ), Red snow rot (Microdochium nivale, Microdochium majus), snow rot sclerotium sclerotium (Typhula incarnata, Typhula ishikariensis), naked smut (Ustilago tritici), stag smut (Tilletia caries, Tilletia controversa), eye spot disease (Pseudocercosporella herpotrichoides), leaf blight (Septoria tritici), blight (Stagonospora nodorum), yellow spot (Pyrenophora tritici-repentis), seedling wilt (Rhizoctonia solani), wilt (Gaeumannomyces graminis) Blast (Pyricularia graminis-tritici);
Barley diseases: Powdery mildew (Blumeria graminis), Fusarium graminearum, Fusarium avenaceum, Fusarium culmorum, Microdochium nivale, Yellow rust (Puccinia striiformis), Black rust (Puccinia graminis), Small rust (Puccinia) hordei), smut (Ustilago nuda), scald (Rhynchosporium secalis), net spot (Pyrenophora teres), spot spot (Cochliobolus sativus), spot leaf spot (Pyrenophora graminea), and lamuraria leaf spot (Ramularia collo-cygni) ), Seedling blight of Rhizoctonia (Rhizoctonia solani);
Corn Diseases: Rust (Puccinia sorghi), Southern Rust (Puccinia polysora), Setophaeria turcica, Tropical Rust (Physopella zeae), Sesame Leaf Blight (Cochliobolus heterostrophus), Anthrax (Colletotrichum graminicola) ), Gray leaf spot disease (Cercospora zeae-maydis), brown spot disease (Kabatiella zeae), Phaeosphaeria leaf spot disease (Phaeosphaeria maydis), Diplodia disease (Stenocarpella maydis, Stenocarpella macrospora), Stokerot disease (Fusarium graminearum, Fusarium verticilioides, Colletotrichum graminicola), smut (Ustilago maydis), huisoderma disease (Physoderma maydis);
Cotton diseases: Anthrax (Colletotrichum gossypii), white mold (Ramularia areola), black spot (Alternaria macrospora, Alternaria gossypii), Black root rot (Thielaviopsis basicola);
Diseases of coffee: rust (Hemileia vastatrix), leaf spot disease (Cercospora coffeicola);
Rapeseed diseases: Sclerotinia sclerotiorum, black spot (Alternaria brassicae), root rot (Phoma lingam), light leaf spot (Pyrenopeziza brassicae);
Sugarcane diseases: rust (Puccinia melanocephela, Puccinia kuehnii), smut (Ustilago scitaminea);
Sunflower diseases: rust (Puccinia helianthi), downy mildew (Plasmopara halstedii);
Citrus diseases: Diaporthe citri, scab (Elsinoe fawcetti), green mold (Penicillium digitatum), blue mold (Penicillium italicum), plague (Phytophthora parasitica, Phytophthora citrophthora), Aspergillus niger (Aspergillus niger) ;
Diseases of apples: Monilinia mali, rot (Valsa ceratosperma), powdery mildew (Podosphaera leucotricha), spot decay (Alternaria alternata apple pathotype), scab (Venturia inaequalis), anthrax (Glomerella triculhumColle) acutatum), brown spot (Diplocarpon mali), ring spot (Botryosphaeria berengeriana), plague (Phytophtora cactorum), scab (Gymnosporangium juniperi-virginianae, Gymnosporangium yamadae);
Diseases of pear: scab (Venturia nashicola, Venturia pirina), black spot (Alternaria alternata Japanese pear pathotype), red scab (Gymnosporangium haraeanum);
Peach diseases: ash disease (Monilinia fructicola), scab (Cladosporium carpophilum), homopsis rot (Phomopsis sp.), Leaf blight (Taphrina deformans);
Grape diseases: Black rot (Elsinoe ampelina), late rot (Glomerella cingulata, Colletotrichum acutatum), powdery mildew (Uncinula necator), rust (Phakopsora ampelopsidis), black rot (Guignardia bidwellii), downy mildew ( Plasmopara viticola);
Oyster diseases: Anthrax (Gloeosporium kaki, Colletotrichum acutatum), deciduous disease (Cercospora kaki, Mycosphaerella nawae);
Diseases of cucumber: Anthrax (Colletotrichum lagenarium), powdery mildew (Sphaerotheca fuliginea), vine blight (Didymella bryoniae), brown spot (Corynespora cassiicola), vine (Fusarium oxysporum), downy mildew (Pseudoperonospora cuben) ), Plague (Phytophthora capsici), seedling blight (Pythium sp.);
Diseases of tomato: ring spot (Alternaria solani), leaf mold (Cladosporium fulvum), scab (Pseudocercospora fuligena), plague (Phytophthora infestans), powdery mildew (Leveillula taurica);
Eggplant diseases: brown spot (Phomopsis vexans), powdery mildew (Erysiphe cichoracearum);
Diseases of cruciferous vegetables: black spot (Alternaria japonica), white spot (Cercosporella brassicae), clubroot (Plasmodiophora brassicae), downy mildew (Peronospora parasitica), white rust (Albugo candida);
Leek diseases: rust (Puccinia allii);
Soybean diseases: purple spot (Cercospora kikuchii), black spot (Elsinoe glycines), black spot (Diaporthe phaseolorum var. Sojae), rust (Phakopsora pachyrhizi), brown ring spot (Corynespora cassiicola), anthracnose (Colletoines glycemic) , Colletotrichum truncatum, Leaf rot (Rhizoctonia solani), Brown spot (Septoria glycines), Leaf spot (Cercospora sojina), Sclerotinia (Sclerotinia sclerotiorum), Powdery mildew (Microsphaera diffusa), Phytophthora sojae , Downy mildew (Peronospora manshurica), sudden death (Fusarium virguliforme), black root rot (Calonectria ilicicola), Diaporthe / Phomopsis complex (Diaporthe longicolla);
Diseases of kidney beans: Sclerotinia sclerotiorum, rust (Uromyces appendiculatus), horn spot (Phaeoisariopsis griseola), anthrax (Colletotrichum lindemuthianum), root rot (Fusarium solani);
Peanut diseases: Black rot (Cercospora personata), brown spot (Cercospora arachidicola), white silk (Sclerotium rolfsii), black root rot (Calonectria ilicicola);
Pea diseases: powdery mildew (Erysiphe pisi), root rot (Fusarium solani);
Potato diseases: summer blight (Alternaria solani), blight (Phytophthora infestans), scarlet rot (Phytophthora erythroseptica), powdery scab (Spongospora subterranea f. Sp. Subterranea), half body wilt (Verticillium albo-atrum, Verticillium) dahliae, Verticillium nigrescens), dry rot (Fusarium solani), carcinomatosis (Synchytrium endobioticum);
Strawberry disease: powdery mildew (Sphaerotheca humuli);
Tea diseases: net blight (Exobasidium reticulatum), white scab (Elsinoe leucospila), ring spot (Pestalotiopsis sp.), Anthrax (Colletotrichum theae-sinensis);
Diseases of tobacco: scab (Alternaria longipes), anthrax (Colletotrichum tabacum), downy mildew (Peronospora tabacina), plague (Phytophthora nicotianae);
Sugar beet diseases: brown spot (Cercospora beticola), leaf rot (Thanatephorus cucumeris), root rot (Thanatephorus cucumeris), black root (Aphanomyces cochlioides), rust (Uromyces betae);
Rose diseases: scab (Diplocarpon rosae), powdery mildew (Sphaerotheca pannosa);
Chrysanthemum diseases: brown spot (Septoria chrysanthemi-indici), white rust (Puccinia horiana);
Diseases of onion: Vitiligo leaf blight (Botrytis cinerea, Botrytis byssoidea, Botrytis squamosa), gray rot (Botrytis allii), microbial rot (Botrytis squamosa);
Diseases of various crops: gray mold (Botrytis cinerea), sclerotia rot (Sclerotinia sclerotiorum), seedling blight (Pythium aphanidermatum, Pythium irregulare, Pythium ultimum);
Radish disease: Black spot (Alternaria brassicicola);
Disease of Shiva: Dollar spot disease (Sclerotinia homoeocarpa), brown patch disease, large patch disease (Rhizoctonia solani), red blight (Pythium aphanidermatum);
Banana diseases: Sigatoka disease (Mycosphaerella fijiensis, Mycosphaerella musicola), Panama disease;
Lentil disease: Ascochyta disease (Ascochyta lentis);
Chickpea disease: Ascochyta disease (Ascochyta rabiei);
Pepper disease: Anthrax (Colletotrichum scovillei);
Mango disease: Anthrax (Colletotrichum acutatum);
Fruit tree diseases: white scab (Rosellinia necatrix), purple scab (Helicobasidium mompa);
Diseases of fruits such as apples and pears after harvesting: Mucor piriformis;
Seed diseases or diseases at the early growth stage caused by Aspergillus, Penicillium, Fusarium, Gibberella, Tricoderma, Thielaviopsis, Rhizopus, Mucor, Corticium, Phoma, Rhizoctonia, Diplodia, and the like;
Viral diseases: Big bain disease of lettuce mediated by Olpidium brassicae, viral diseases of various crops mediated by the genus Polymyxa (eg, Polymyxa betae and Polymyxa graminis);
Diseases caused by bacteria (Bacteria): Seedling blight of rice (Burkholderia plantarii), spot bacterial disease of cucumber (Pseudomonas syringae pv. Lachrymans), bacterial wilt of eggplant (Ralstonia solanacearum), citrus canker (Xanthomonas citri) ), Chinese cabbage soft rot (Erwinia carotovora), potato scab (Streptomyces scabiei), maize Goss's wilt disease (Clavibacter michiganensis), grape, olive, peach and other piercing diseases (Xylella fastidiosa), apple, peach, cherry Agrobacterium tumefaciens of root plants of Rosaceae plants.

  Regarding the above-described phytopathogenic microorganisms, intra-species variation is not particularly limited. That is, those having decreased sensitivity (also referred to as exhibiting resistance) to a specific fungicide are included. The reduction in sensitivity may be due to a mutation at the target site (action point mutation) or may be due to factors other than the action point mutation (non-action point mutation). Regarding the action point mutation, a mutation in the nucleic acid sequence portion (open reading frame) corresponding to the amino acid sequence of the protein results in an amino acid substitution in the target site protein, a deletion of the suppressor sequence in the promoter region, or an enhancer. Includes those where the protein at the target site is overexpressed due to mutations such as amplification of the sequence or increase in the copy number of the gene. Non-action point mutations include, for example, enhancement of the efflux function of excreting the bactericide that has flowed into the cell to the outside by the ABC transporter, MFS transporter, and the like. Detoxification by disinfectant metabolism is also included.

  Examples of the specific bactericide include nucleic acid synthesis inhibitors (for example, phenylamide-based bactericide, acylamino acid-based bactericide, DNA topoisomerase type II bactericide), mitosis and cell division inhibitors (for example, MBC fungicide, N-phenylcarbamate fungicide), respiratory inhibitor (e.g., QoI fungicide, QiI fungicide, SDHI fungicide), inhibitor of amino acid synthesis and protein synthesis (e.g., anilinopyrimidine fungicide), Signal transduction inhibitors (eg, phenylpyrrole fungicides, dicarboximide fungicides), inhibitors of lipid synthesis and cell membrane synthesis (eg, phosphorothiolate fungicides, dithiolane fungicides, aromatic hydrocarbon fungicides, Heteroaromatic fungicides, carbamate fungicides), sterol biosynthesis inhibitors (eg, triazole-based DM Fungicides, hydroxyanilide fungicides, aminopyrazolinone fungicides), cell wall synthesis inhibitors (e.g., polyoxin fungicides, carboxylic amide fungicides), melanin synthesis inhibitors (e.g., MBI-R fungicides) , MBI-D fungicides, MBI-P fungicides, and other fungicides (for example, cyanoacetamide oxime fungicides, phenylacetamide fungicides).

  Examples of the amino acid substitution at the target site include the following.

Cytochrome b: G143A, F129L or G137R;
A311G, A379G, A381G, A410T, A61V, D107V, D134G, D282E, D411N, E297K, F120L, F219S, F449S, F489L, F495I, G138C / R / S, G312A, G412A, G432S, G434C, G460S for Cyp51 protein / Δ, G462A, G464S, G484S, G510C, G54E / K / R / V / W, G54W, H147Y, H303Y, H399P, I145F, I330T, I381V / Δ, I471T, I475T, K142R, K143E, K147Q, K175N, K197N , L50S, L98H, M145L, M220K / I / T / V, M288L, N125I, N178S, N22D, N284H, N513K, P216L, P384S, P394L, Q141H, Q88H, R467K, S188N, S208T, S297T, S405F, S508T, S509T , S524T, S52T, S79T, T289A, T440A, T454P, T469S, V101F, V136A / C / G, V490L, Y121F, Y131F / H, Y132F / H / N, Y134F, Y134F, Y136F, Y137F, Y140F / H, Y145F , Y431C, Y459C / D / N / S / P / Δ, Y461D, Y461D / H / S, Y463D / H / N, Y491H or Y68N;
β-tubulin: H6L / Y, Y50C / N / S, Q134K, A165V, E198A / D / G / K / L / Q / V, F200Y, M257L, F200Y, F167Y, Q73R or L240F;
SdhB: H277R / Y, P225H / F / L / T, N230I, H272L / R / V / Y, H278Y / R, H249L / N / Y, H273Y, N225I / T, T268I / A, I269V, H242R, H257L or T253I;
SdhC: H134R, P80H / L, A85V, S73P, T90I, I86F, N88S, H154Y / R, K49E, R64K, N75S, G79R, S135R, N87S, H153R, H146R, I29V, N33T, N34T, T79I / N, W80S, A84V, N86K / S / A, G90R, R151T / S, H152R, I161S, G169D or H151R;
SdhD: H133R, H132R, S89P, G109V, D124E / N, H134R, G138V, D145G, I50F, M114V or D129E;
OS-1 (Shk1): E753K, G420D, I365N / R / S, V368F, Q369H / P, N373S, T447S, F267L, L290S, T765R, Q777R, T489I, E599K or G736Y;
ERG27: S9G, F26S, P57A, T63I, G170R, V192I, L195F, N196T, A210G, I232M, P238S / Δ, P250S, P269L, P298Δ, V309M, A314V, S336C, V365A, E368D, N369D, E375K, A378T / L400F S, Y408S, F412I / S / V / C, A461S or R496T.

  In addition, the following are examples of phytopathogenic microorganisms whose susceptibility to fungicides has been reduced due to overexpression of the Cyp51 gene and their host plants. Wheat Septoria tritici (Reference: Pest Management Science. 2012. 68 (7) .1034-1040), barley Rhynchosporium secalis (Reference: Molecular Bilogy and Evolution. 2014. 31 (7) .1793-1802) soybean Phakopsora pachyrhizi (reference: Pest Management Science. 2014. 70 (3) .378-388), apple Venturia inaequalis (reference: Phytopathology. 2016. 106 (6) .562-571), citrus Penicillium digitatum (reference) Reference: Applied and Environmental Microbiology. 2000. 66 (8) .3421-3426).

  The phytopathogenic microorganism which can be controlled by the composition of the present invention may have a plurality of the above amino acid substitutions. In this case, the plurality of amino acid substitutions may be the same protein or different proteins. Further, it may have a plurality of non-action point mutations and a plurality of action point mutations. For example, a phytopathogenic microorganism causing an amino acid substitution of G143A, F129L and G137R in cytochrome b; a phytopathogenic microorganism having an amino acid substitution of G143A in cytochrome b and having an amino acid substitution of A311G in Cyp51; G143A and A phytopathogenic microorganism having an amino acid substitution of F129L and having an amino acid substitution of A311G in Cyp51; having an amino acid substitution of G143A and F129L in cytochrome b, and having an amino acid substitution of H6L / Y in β-tubulin. And a phytopathogenic microorganism overexpressing the Cyp51 gene.

  Examples of the phytopathogenic microorganism having an action point mutation include the following.

Alternaria alternata having an amino acid substitution of G143A on cytochrome b;
Alternaria arborescens having an amino acid substitution of G143A in cytochrome b;
Alternaria solani having an amino acid substitution of F129L in cytochrome b;
Alternaria tomato having an amino acid substitution of G143A in cytochrome b;
Botryotinia fuckeliana having an amino acid substitution of G143A in cytochrome b;
Glomerella graminicola having a G143A amino acid substitution in cytochrome b;
Corynespora cassiicola having an amino acid substitution of G143A in cytochrome b;
Cercospora beticola having a G143A amino acid substitution in cytochrome b;
Cercospora sojina having an amino acid substitution of G143A on cytochrome b;
Cladsporium carpophilum having a G143A amino acid substitution in cytochrome b;
Colletotrichum graminicola having an amino acid substitution of G143A in cytochrome b;
Glomerella cingulata having a G143A amino acid substitution in cytochrome b;
Blumeria graminis f. Sp. Hordei having a G143A amino acid substitution in cytochrome b;
Blumeria graminis f. Sp. Tritici having an amino acid substitution of G143A in cytochrome b;
Parastagonospora nodorum having an amino acid substitution of G143A in cytochrome b;
Monographella nivalis having an amino acid substitution of G143A in cytochrome b;
Microdochium majus, nivale having a G143A amino acid substitution in cytochrome b;
Mycosphaerella fijiensis having a G143A amino acid substitution in cytochrome b;
Didymella rabiei having a G143A amino acid substitution in cytochrome b;
Phakopsora pachyrhizi having an amino acid substitution of F129L in cytochrome b;
Plasmopara viticola having an amino acid substitution of F129L or G143A in cytochrome b;
Pleospora allii having a G143A amino acid substitution in cytochrome b;
Podosphaera fusca having a G143A amino acid substitution in cytochrome b;
Podosphaera xanthii having a G143A amino acid substitution in cytochrome b;
Pseudoperonospora cubensis having a G143A amino acid substitution in cytochrome b;
Magnaporthe oryzae having an amino acid substitution of F129L or G143A in cytochrome b;
Pyrenophora teres having an amino acid substitution of F129L in cytochrome b;
Pyrenophora tritici-repentis having an amino acid substitution of F129L, G137R or G143A in cytochrome b;
Pythium aphanidermatum having an amino acid substitution of F129L in cytochrome b;
Thanatephorus cucumeris having an amino acid substitution of F129L or G143A in cytochrome b;
Ramularia collo-cygni having a G143A amino acid substitution in cytochrome b;
Rhynchosporium secalis having a G143A amino acid substitution in cytochrome b;
Rhizoctonia solani having an amino acid substitution of F129L in cytochrome b;
Zymoseptoria tritici having an amino acid substitution of F129L, G137R or G143A in cytochrome b;
Erysiphe necator having an amino acid substitution of G143A in cytochrome b;
Venturia inaequalis having an amino acid substitution of G143A in cytochrome b;
Ajellomyces capsulatus having an amino acid substitution of Y136F on Cyp51;
Aspergillus flavus having an amino acid substitution of Y132N, K197N, D282E, M288L, T469S, H399P, D411N or T454P in Cyp51;
Cyp51 to N22D, S52T, G54E / K / R / V / W, Y68N, Q88H, L98H, V101F, Y121F, N125I, G138C / R / S, Q141H, H147Y, P216L, F219S, M220K / I / T / V, Aspergillus fumigatus having an amino acid substitution of T289A, S297T, P394L, Y431C, G432S, G434C, T440A, G448S, Y491H or F495I;
Aspergillus parasiticus having a G54W amino acid substitution in Cyp51;
Candida albicans having an amino acid substitution of A61V, Y132F / H, K143E, S405F, F449S, G464S, R467K or I471T in Cyp51;
Cercospora beticola having an amino acid substitution of E297K, I330T or P384S on Cyp51;
Blumeria graminis f. Sp. Hordei having an amino acid substitution of Y136F, K147Q or S509T in Cyp51;
Blumeria graminis f. Sp. Tritici having an amino acid substitution of S79T, Y136F, or K175N in Cyp51;
Filobasidiella neoformans having an amino acid substitution of Y145F or G484S in Cyp51;
Monilinia fructicola having an amino acid substitution of Y136F on Cyp51,
Mycosphaerella fijiensis having an amino acid substitution of Y136F, A313G, A381G, Y461D, G462A or Y463D / H / N in Cyp51;
Phakopsora pachyrhizi with F120L, Y131F / H, K142R, I145F or I475T amino acid substitutions on Cyp51;
Puccinia triticina having an amino acid substitution of Y134F on Cyp51;
Pyrenophora teres having an amino acid substitution of F489L in Cyp51;
Pyrenopeziza brassicae having an amino acid substitution of S508T in Cyp51;
Saccharomyces cerevisiae having an amino acid substitution of Y140F / H in Cyp51;
L50S, D107V, D134G, V136A / C / G, Y137F, M145L, N178S, S188N, S208T, N284H, H303Y, A311G, G312A, A379G, I381V / Δ, A410T, G412A, Y459C / D / N / S / Zymoseptoria tritici with an amino acid substitution of P / Δ, G460D / Δ, Y461D / H / S, V490L, G510C, N513K or S524T;
Erysiphe necator having an amino acid substitution of Y136F on Cyp51;
Emericella nidulans having an amino acid substitution of H6L / Y, Y50N / S, Q134K, A165V, E198D / K / Q, F200Y or M257L in β-tubulin;
Botryotinia fuckeliana having an amino acid substitution of E198A / G / K / V or F200Y in β-tubulin;
Cochliobolus heterostrophus having an amino acid substitution of F167Y in β-tubulin;
Cercospora beticola having an amino acid substitution of F167Y or E198A in β-tubulin;
Gibberella fujikuroi having an amino acid substitution of Y50N, E198V or F200Y in β-tubulin;
Gibberella zeae having an amino acid substitution of Y50C, Q73R, F167Y, E198K / L / Q or F200Y in β-tubulin;
Helminthosporium solani having an amino acid substitution of E198A / Q in β-tubulin;
Hypomyces odoratus having an amino acid substitution of Y50C in β-tubulin;
Parastagonospora nodorum having an amino acid substitution of H6Y in β-tubulin;
Monilinia fructicola having an amino acid substitution of H6Y or E198A / K in β-tubulin;
Monilinia laxa having an amino acid substitution of L240F in β-tubulin;
Microdochium majus, nivale having an amino acid substitution of E198A in β-tubulin;
Mycosphaerella fijiensis having an amino acid substitution of E198A in β-tubulin;
Neurospora crassa having an amino acid substitution of F167Y or E198G in β-tubulin;
Penicillium aurantiogriseum having an amino acid substitution of E198A / K or F200Y in β-tubulin;
Penicillium expansum having F167Y or E198A / K / V amino acid substitution in β-tubulin;
Penicillium italicum having an E198K or F200Y amino acid substitution in β-tubulin;
Pyrenopeziza brassicae having an amino acid substitution of L240F in β-tubulin;
Rhynchosporium secalis having an amino acid substitution of E198G / K or F200Y in β-tubulin;
Sclerotinia homoeocarpa having an amino acid substitution of E198A / K in β-tubulin;
Sclerotinia sclerotiorum having an amino acid substitution of E198A in β-tubulin;
Zymoseptoria tritici having an amino acid substitution of E198A / G in β-tubulin;
Venturia inaequalis having an amino acid substitution of E198A / K, F200Y or L240F in β-tubulin;
Alternaria alternata having an amino acid substitution of H277R / Y in SdhB;
Alternaria solani having an amino acid substitution of H277R / Y in SdhB,
Botryotinia fuckeliana having an amino acid substitution of P225H / F / L / T, N230I or H272L / R / V / Y in SdhB;
Corynespora cassiicola having an amino acid substitution of H278Y / R in SdhB;
Stagonosporopsis cucurbitacearum having an amino acid substitution of H277R / Y in SdhB;
Eurotium oryzae having an amino acid substitution of H249L / N / Y in SdhB;
Pyrenophora teres having an amino acid substitution of H277Y in SdhB;
Sclerotinia sclerotiorum having an amino acid substitution of H273Y in SdhB;
Zymoseptoria tritici having an amino acid substitution of N225I / T, H273Y, T268I / A or I269V in SdhB;
Erysiphe necator having an amino acid substitution of H242R in SdhB;
Ustilago maydis having an amino acid substitution of H257L in SdhB;
Venturia inaequalis having a T253I amino acid substitution in SdhB;
Alternaria alternata having an amino acid substitution of H134R in SdhC;
Botryotinia fuckeliana having a P80H / L or A85V amino acid substitution in SdhC;
Corynespora cassiicola having an amino acid substitution of S73P in SdhC;
Eurotium oryzae having a T90I amino acid substitution in SdhC;
Phakopsora pachyrhizi with an amino acid substitution of I86F, N88S or H154Y / R in SdhC;
Pyrenophora teres having K49E, R64K, N75S, G79R, H134R or S135R amino acid substitutions in SdhC;
Ramularia collo-cygni having an N87S, H146R or H153R amino acid substitution in SdhC;
Sclerotinia sclerotiorum having an amino acid substitution of H146R in SdhC;
Zymoseptoria tritici having an amino acid substitution of I29V, N33T, N34T, T79I / N, W80S, A84V, N86K / S / A, G90R, R151T / S, H152R or I161S in SdhC;
Erysiphe necator having a G169D amino acid substitution in SdhC;
Venturia inaequalis having an amino acid substitution of H151R in SdhC;
Alternaria alternata having an amino acid substitution of H133R in SdhD;
Alternaria solani having an amino acid substitution of H133R in SdhD;
Botryotinia fuckeliana having an amino acid substitution of H132R in SdhD;
Corynespora cassiicola having an amino acid substitution of S89P or G109V in SdhD;
Eurotium oryzae having an amino acid substitution of D124E in SdhD;
Pyrenophora teres having an amino acid substitution of D124E / N, H134R, G138V or D145G in SdhD;
Sclerotinia sclerotiorum having an amino acid substitution of H132R in SdhD;
Zymoseptoria tritici having an amino acid substitution of I50F, M114V or D129E in SdhD;
Phytophthora capsici having an amino acid substitution of Q1077K or V1109L / M in CesA3;
Phytophthora drechsleri having a V1109L amino acid substitution in CesA3;
Phytophthora infestans having a G1105A / V or V1109L amino acid substitution in CesA3;
Plasmopara viticola having a G1105S / V amino acid substitution in CesA3;
Pseudoperonospora cubensis having a G1105V / W amino acid substitution in CesA3;
Alternaria brassicicola having an amino acid substitution of E753K in OS-1 (Shk1);
Alternaria longipes having an amino acid substitution of G420D in OS-1 (Shk1);
Botryotinia fuckeliana with an amino acid substitution of I365N / R / S, V368F, Q369H / P, N373S or T447S in OS-1 (Shk1);
Pleospora allii having an amino acid substitution of F267L, L290S, T765R or Q777R in OS-1 (Shk1);
Sclerotinia sclerotiorum having a T489I, E599K or G736Y amino acid substitution in OS-1 (Shk1);
ERG27 has S9G, F26S, P57A, T63I, G170R, V192I, L195F, N196T, A210G, I232M, P238S / Δ, P250S, P269L, P298Δ, V309M, A314V, S336C, V365A, E368D, N369D, E375K, A378T / L400F Botryotinia fuckeliana having an amino acid substitution of S, Y408S, F412I / S / V / C, A461S or R496T.

  Zymoseptoria tritici means the same species as Septoria tritici.

Examples of the combination of the main drug substance and the minor drug substance in the composition of the present invention and the method of the present invention are listed in Table 1 below together with the weight ratio, but are not limited thereto. That is, even if the combination is not specifically disclosed in Table 1, any combination of any two compounds selected from the compound group A is considered to be disclosed. In addition, for a method for controlling any pest weeds in any crop, in a combination of any two compounds selected from the compound group A, an appropriate ratio and application rate can be appropriately set by those skilled in the art. . In particular, a dent corn (field corn), an infinitely extensible soybean, a finite elongation in a combination disclosed in Table 1 or a combination of any two compounds selected from the compound group A not specifically disclosed in Table 1 The treatment of seeds, foliage treatment, or soil treatment (including in-furrow treatment) on sex soybean, spring sowing canola, spring sowing hard wheat, upland cotton, and the like is described in this specification. It is considered to be disclosed at all drug substance ratios and dosages. Further, for the combination disclosed in Table 1 or the combination of any two compounds selected from the compound group A not specifically disclosed in Table 1, one or more different compounds are further added. It is also possible to combine the same amount as that of the main drug substance, to combine them in the range of the weight ratio of the minor drug substance, or to carry out both of them. In addition, Table 1 is described separately from Table 1-1 to Table 1-306. As described above, the caret symbol “＾” is an operator representing a power (for example, 10 ＾ 15 means 10 ¹⁵ ).

  In the cultivation of crops according to the present invention, plant nutritional management in general cultivation of crops can be performed. The fertilizer application system may be a Vriable Rate Application based on Precision Aggregation, or may be a uniform practice. In addition, nitrogen-fixing bacteria or mycorrhizal fungi can be inoculated in combination with seed treatment.

  Hereinafter, the present invention will be described with reference to examples, but the present invention is not limited to these examples.

Formulation Example 1
A preparation is obtained by thoroughly pulverizing and mixing 50 parts of any one of the drug substance combinations shown in Table 1, 3 parts of calcium ligninsulfonate, 2 parts of magnesium lauryl sulfate and 45 parts of wet silica.

Formulation Example 2
20 parts of any one of the active ingredients in Table 1 and 1.5 parts of sorbitan trioleate were mixed with 28.5 parts of an aqueous solution containing 2 parts of polyvinyl alcohol, and finely pulverized by a wet pulverization method. , 40 parts of an aqueous solution containing 0.05 parts of xanthan gum and 0.1 parts of aluminum magnesium silicate are added, and 10 parts of propylene glycol are further added and mixed by stirring to obtain a preparation.

Formulation Example 3
A formulation is obtained by thoroughly pulverizing and mixing 2 parts of any one of the active ingredients shown in Table 1, 88 parts of kaolin clay and 10 parts of talc.

Formulation Example 4
A formulation is obtained by thoroughly mixing 5 parts of any one of the drug substance combinations shown in Table 1, 14 parts of polyoxyethylene styrylphenyl ether, 6 parts of calcium dodecylbenzenesulfonate and 75 parts of xylene.

Formulation Example 5
2 parts of any one of the active ingredients shown in Table 1, 1 part of wet silica, 2 parts of calcium lignin sulfonate, 30 parts of bentonite and 65 parts of kaolin clay are thoroughly pulverized and mixed. The preparation is obtained by drying.

Formulation Example 6
35 parts of a mixture of a polyoxyethylene alkyl ether sulfate ammonium salt and wet silica (weight ratio of 1: 1), 20 parts of any one of the raw material combinations shown in Table 1, and 45 parts of water were thoroughly mixed, and the formulation was prepared. obtain.

  According to the present invention, pests can be efficiently controlled.

Claims (3)

An agricultural chemical compound (a1) selected from the following compound group A and an agricultural chemical compound (a2) selected from the following compound group A, wherein the weight ratio of the agricultural chemical compound (a1) to the agricultural chemical compound (a2) is A pesticide composition wherein the ratio of compound (a2) / pesticide compound (a1) is 1/1000 or less.
[Compound group A:
At least one compound selected from the following compounds, which is a herbicide compound;
2,3,6-TBA (2,3,6-trichlorobenzoic acid), 2,4-D, 2,4-DB, acetochlor (acetochlor), acifluorfen (acifluorfen), acronifen (aclonifen), ACN ( 2-amino-3-chloronaphthalene-1,4-dione), alachlor (alachlor), alidochlor (allidochlor), alloxydim (alloxydim), amethrin (ametryn), amicarbazone (amicarbazone), amidosulfuron, aminocyclo Pyracrol (aminocyclopyrachlor), aminocyclopyrachlor-methyl (aminocyclopyrachlor-methyl), aminopyralid (aminopyralid), amiprophos-methyl (amiprophos-methyl), amitrole (amitrole), anilofos (anilofos), ashram (asulam), atrazine (atrazine) ), Azafenidin, azimsulfuron, beflubutamid, benazolin-ethyl yl), bencarbazone (bencarbazone), benfluralin (benfluralin), benfresate (benfuresate), bensulfuron (bensulfuron), bensulfuron-methyl (bensulfuron-methyl), bensulide (bensulide), bentazon (bentazon), benthiocarb (benthiocarb), benzfen Dizone (benzfendizone), benzobicyclon (benzobicyclon), benzofenap (benzofenap), benzthiazuron (benzthiazuron), bialaphos (bialafosbialaphos), bicyclopyrone (bicyclopyrone), bifenox (bifenox), bispyribac (bixlozone) (bixlozone) , Bromacil, bromobutide, bromofenoxim, bromoxynil, bromoxynil-octanoate, butachlor, butafenasi (Butafenacil), butamifos (butamifos), buturerin (butralin), butroxydim (butroxydim), butyrate (butylate), cafenstrole (cafenstrole), carbetamide (carbetamide), carfentrazone (carfentrazone), carfentrazone ethyl (carfentrazone) -ethyl), chloromethoxyfen, chloramben, chloridazone, chlorimuron, chlorimuron, chlorimuron-ethyl, chlorobromuron, chlorotomuron, chloroxuron chloroxuron), chlorpropham, chlorsulfuron, chlorthal-dimethyl, chlorthiamide, chlorthiamid, sinidone, sinidon-ethyl, cinmethylin (cinmethyli) n), sinosulfuron, clethodim, clodinafop, clodinafop, clodinafop-propargyl, clomazone, clomazone, clomeprop, clopyralid, cloransulam, cloransulam Rhammethyl (cloransulam-methyl), cumyluron, cyanazine, cyclopyranil, cyclopyranil, cycloate, cyclopyrimorate, cyclosulfamuron, cyclosulfamuron, cycloxydim, cyhalofop (Cyhalofop), cyhalofop-butyl, daimuron, dalapon, dazomet, dazomet, desmedipham, desmethrin, desmetryn, di-allate, dicamba , Clovenil (dichlobenil), dicloprop (dichlorprop), dicloprop 2-ethylhexyl (dichlorprop-2-ethylhexyl), dicloprop butyl (dichlorprop-butotyl), dicloprop isooctyl (dichlorprop-isoctyl), dicloprop-methyl (dichlorprop- methyl), dicloprop P (dichlorprop-P), dicloprop P 2-ethylhexyl (dichlorprop-P-2-ethylhexyl), diclohop (diclofop), diclohopmethyl (diclofop-methyl), dicloslam (diclosulam), difenoxuron (difenoxuron) ), Difenzoquat, difenzoquat methyl sulfate (difenzoquat metilsulfate), diflufenican, diflufenzopyr, diflufenzopyr, diflufenzopyr-sodium, dimefuron, dimefuronate (Dimepip erate), dimethachlor, dimethametryn, dimethenamid, dimethenamid P (dimethenamid-P), dimepiperate, dinitramine, dinoseb, dinoterb, dinoterb , Diquat, diquat-dibromide, DSMA (disodium methylarsonate), dithiopyr, diuron, DNOC (2-methyl-4,6-dinitrophenol), esprocarb, esprocarb Fluralin (ethalfluralin), ethametsulfuron (ethametsulfuron), ethametsulfuron-methyl (ethametsulfuron-methyl), ethidimuron (ethidimuron), ethofumesate (ethofumesate), ethoxyfen-ethyl, ethoxysulfuronide, ethoxysulfuronide (Etobenzanid ), Fenoxaprop, fenoxaprop-ethyl, fenoxaprop-P, fenoxaprop-P, fenoxaprop-P-ethyl, fenoxasulfone, fen Quinotrione (fenquinotrione), fentrazamide, fenuron, fenuron M, flamprop-M, flazasulfuron, floraslam, florasulam, florpyrauxifen, florpyrauxifene benzyl (Florpyrauxifen-benzyl), fluazifop (fluazifop), fluazifop-butyl (fluazifop-butyl), fluazifop P (fluazifop-P), fluazifop-P-butyl (fluazifop-P-butyl), fluazolate (fluazolate), flucarbazone (flucarbazone), Flucetosulfuron, full Phenacet (flufenacet), flufenpyr (flufenpyr), flufenpyr-ethyl (flufenpyr-ethyl), flumetetsulam (flumetsulam), flumethoslam (flumetsulam), flumicrolac (flumiclorac), flumiclorac-pentyl, fluometuron ( fluometuron), fluoroglycofen-ethyl, flupoxam, flupropanate, flupropansulfuron, flupyrsulfuron, flupyrsulfuron-methyl-sodium, flurenol, Fluridone (fluridone), flurochloridone (flurochloridone), fluoxypyr (fluroxypyr), fluoxypyrbutomethyl (fluroxypyr-butometyl), fluoxypyreptyl (fluroxypyr-meptyl), flurtamone (flurtamone), fluthiacet (fluthiacet), Fluthiacet-methyl, fomesafen, fomesafen-sodium, foramsulfuron, fosamine, glufosinate, glufosinate-P, glufosinate-P (Glyphosate), halauxifen, halauxifen-methyl, halosafen, halosulfuron, halosulfuron-methyl, haloxyfop, haloxyfop et Tyl (haloxyfop-etotyl), haloxyfop-methyl, haloxyfop-P, haloxyfop-P-ethtyl, haloxyfop-P-methyl, haloxyfop-P-methyl, hexazinone ), Imazamethabenz, imaza Tavenzmethyl (imazamethabenz-methyl), imazamox (imazamox), imazapic (imazapic), imazapyr (imazapyr), imazaquin (imazaquin), imazethapyr (imazethapyr), imazosulfuron (imazosulfuron), indanofan (indanofan), indanofan, indanofando (Iodosulfuron), iodosulfuron-methyl-sodium, iofensulfuron, ioxynil, ioxynil-octanoate, ipfencarbazone, isoproturon (Isoproturon), isouron, isoxaben, isoxachlortole, isoxaflutole, isoxaflutole, lactofen, lenacil, linuron, male Maleic hydrazide, MCPA (2- (4-chloro-2-methylphenoxy) acetic acid), MCPB (4- (4-chloro-2-methylphenoxy) butanoic acid), mecoprop (mecoprop), mecoprop P ( mecoprop-P), mefenacet (mefenacet), meso-sulfuron (mesosulfuron), meso-sulfuron-methyl (mesosulfuron-methyl), mesotrione (mesotrione), metatam (metam), metamihop (metamifop), metamitron (metamitron), metazachlor (metazachlor), Metazosulfuron, methabenzthiazuron, methiozolin, methyzimolin, methyldymron, metobromuron, metolachlor, metosuron, metoxuron, metoxuron, metoxuron , Metsulfuron, metsulfuron methyl (mets ulfuron-methyl), molinate, monolinuron, naproanilide, napropamide, napropamide M, napropamide-M, naptalam, neburon, nicosulfuron, norflurazon (Norflurazon), oleic acid, orbencarb, orthosulfamuron, oryzalin, oryzalin, oxadiargyl, oxadiazon, oxasulfuron, oxaziclomefone , Oxyfluorfen, paraquat, paraquat-dichloride, pebulate, pelargonic acid, pendimethalin, penoxsulam, pen Tanocrol (pentanochlor), pentoxazone (pentoxazone), petoxamide (pethoxamid), phenisopham (phenisopham), phenmedipham (phenmedipham), picloram (picloram), pyrocorinafen (picolinafen), pinoxaden (pinoxaden), piperophos (piperophos) (Pretilachlor), primisulfuron (primisulfuron), primisulfuron-methyl (primisulfuron-methyl), prodiamine (prodiamine), profluazole (profluazol), propoxydim (profoxydim), prometon (prometon), promethrin (prometryn), Propachlor, propanil, propaquizafop, propazine, propham, propham, propisochlor, propoxycarbazone, propirisulfur (Propyrisulfuron), propyzamide, prosulfocarb, prosulfuron, pyraclonil, pyraclonil, pyraflufen-ethyl, pyrasulfotole, pyrazolynate, pyrazosulfuron ), Pyrazosulfuron-ethyl, pyrazoxyfen, pyribenzoxim, pyributicarb, pyributicarb, pyridafol, pyridate, pyridate, pyriftalid, pyriminobac, pyriminobac Methyl (pyriminobac-methyl), pyrimisulfan, pyrithiobac, pyroxasulfone, pyroxyslam, pyroxsulam, quinclorac, quinmerac (Quinmerac), quizalofop-ethyl, quizalofop-ethyl, quizalofop-tefuryl, quizalofop-P, quizalofop-P-ethyl, quizalofop-P-ethyl, quizalofop P-tefuril (quizalofop-P-tefuryl), rimsulfuron, saflufenacil, sethoxydim, sethoxydim, EPTC (S-ethyl N, N-dipropylcarbamothioate), siduron, siduron, simazine, simethrin ( simetryn), S-metolachlor (S-metolachlor), MSMA (sodium hydrogen methylarsonate), sulcotrione (sulcotrione), sulfentrazone (sulfentrazone), sulfometuron (sulfometuron), sulfometuron-methyl (sulfometuron-methyl), TCA Ethazyl (TCA-ethadyl), sulfosulfuron, swep, TCA (2,2,2-trichloroacet) ic acid), tebutam, tebuthiuron, tefuryltrione, tebotrione, tembotrione, tepraloxydim (tepraloxydim), terbacil, terbumeton, terbuthylazine, terbuthylazine terbutryn), tetflupyrolimet (tetflupyrolimet), taxomin A (thaxtomin A), tenylchlor (thenylchlor), thiazopyr (thiazopyr), thidiadimine (thidiazimin), thiencarbazone (thiencarbazone), thiencarbazone-methyl, thiencarbazone-methyl Luflon (thifensulfuron), thifensulfuron-methyl, thiafenacil, thioafazil, tiocarbazil, tolpyralate, topramezone, tralkoxydim, tril Phamon (triafamone), trialate (tri-allate), triasulfuron (triasulfuron), triaziflam (triaziflam), tribenuron (tribenuron), tribenuron-methyl (tribenuron-methyl), triclopyr (triclopyr), triclopyrbutyr ( triclopyr-butotyl, triclopyr-ethyl, triclopyr-triethylammonium, tridiphane, trietazine, trietazine, trifloxysulfuron, trifloxysulfuron sodium salt -sodium), trifludimoxazin, trifluralin, triflusulfuron, triflusulfuron-methyl, tritosulfuron-methyl, tritosulfuron, vernolate, formula (1) ):

X, 4- (4-fluorophenyl) -6-[(2-hydroxy-6-oxo-1-cyclohexen-1-yl) carbonyl] -2-methyl-1,2,4-triazine-3 , 5 (2H, 4H) -dione, 2-chloro-N- (1-methyl-1H-tetrazol-5-yl) -3- (methylthio) -4- (trifluoromethyl) benzamide, 2-methyl-N- ( 5-methyl-1,3,4-oxadiazol-2-yl) -3- (methanesulfonyl) -4- (trifluoromethyl) benzamide, 4-amino-3-chloro-5-fluoro-6- (7-fluoro-1H -indol-6-yl) pyridine-2-carboxylic acid,
At least one compound selected from the following compounds, which is a safener;
Benoxacor, cloquintocet, cloquintocet-mexyl, cyometrinil, cyometrinil, cyprosulfamide, dichlormid, dicyclonone, disulfoton , Daimuron, fenchlorazole, fenchlorazole-ethyl, fenclorim, fluclosol, flurazole, furilazole, furoxoazole, fluxofenim, hexim, isoxadifen isoxadifen), isoxadifen-ethyl, mefenpyr, mefenpyr-ethyl, mefenpyr-diethyl, mefenpyr-diethyl, mefenate, mefamifen, metokimifen Betrinil (oxabetrinil), 1,8-naphthalic anhydride, octane-1,8-diamine, AD-67 (4- (dichloroacetyl) -1 -oxa-4-azaspiro [4.5] decane), CL-304415 (4-carboxy-3,4-dihydro-2H-1-benzopyran-4-acetic acid), CSB (1-bromo-4-[(chloromethyl)) sulfonyl] benzene), DKA-24 (2,2-dichloro-N- [2-oxo-2- (2-propenylamino) ethyl] -N- (2-propenyl) acetamide), MG191 (2- (dichloromethyl)- 2-methyl-1,3-dioxolane), MG-838 (2-propenyl 1-oxa-4-azaspiro [4.5] decane-4-carbodithioate), PPG-1292 (2,2-dichloro-N- (1, 3-dioxan-2-ylmethyl) -N- (2-propenyl) acetamide), R-28725 (3- (dichloroacetyl) -2,2-dimethyl-1,3-oxazolidine), R-29148 (3- (dichloroacetyl ) -2,2,5-trimethyl-1,3-oxazolidine), TI-35 (1- (dichloroacetyl) azepane),
At least one compound selected from the following compounds, which is a fungicide compound;
Acibenzolar-S-methyl, aldimorph, amethoctradin, aminopyrifen, amisulbrom, ammonium salts of phosphorous acid, anilazine ), Azaconazole, azoxystrobin, basic copper sulfate, benalaxyl, benalaxyl M (benalaxyl-M), benodanil, benomyl, benomyl Baricarb (benthiavalicarb), Benthiivalicarb-isopropyl, benzovindiflupyr, binapacryl (binapacryl), biphenyl, biphenyl, bitertanol, bixafen, blasticidin S ( blasticidin-S), Bordeaux solution (Bo rdeaux mixture), boscalid, bromothalonil, bromuconazole, bupirimate, calcium salts of phosphorous acid, captafol, captan ), Carbendazim, carboxin, carpropamide, quinomethionate, chitin, chloroneb, chlorothalonil, chlorozolinate, coletochlorin B , Copper (II) acetate, copper (II) hydroxide, copper (II) hydroxide, basic oxychloride, copper (II) sulfate, Coumoxystrobin, cyazofamid, cyflufenamide, cymoxanil (Cymoxanil), cyproconazole, cyprodinil, cyprodinil, dichlobentiazox, dichlofluanid, dichlofluanid, diclosymet, diclomezine, diclofen, dithofencarb , Difenoconazole (difenoconazole), diflumetorim, dimethachlone, dimethirimol, dimethirimol, dimethomorph, dimoxystrobin, diniconazole, diniconazole M, diniconazole-d ), Dipotassium hydrogenphosphite, dipymetitrone, dithianon, dodecylbenzenesulfonate bisethylenediamine copper (II) complex (dodecylbenzenesulphonic) acid bisethylenediamine copper (II) salt), dodemorph, dodine, edifenphos, enoxastrobin, enoxistrobin, epoxyconazole, epoxiconazole, etaconazole, ethaboxam, etirimol ( ethirimol), etridiazole (etridiazole), famoxadone, fenamide (fenamidone), phenaminestrobin (fenaminstrobin), fenarimol (fenarimol), fenbuconazole (fenbuconazole), fenfuram (fenfuram), fenhexamide (fenhexamid), Fenoxanil, fenpiclonil, fenpicoxamide, fenpropidin, fenpropidmorph, fenpropimorph, fenpyrazamine, triphenyltin acetate acetate), triphenyltin chloride (fentin chloride), triphenyltin hydroxide (fentin hydroxide), ferbam (ferbam), ferimzone (ferimzone), florylpicoxamide (florylpicoxamid), fluazinam (fluazinam), fludioxonil (fludioxonil) , Flufenoxystrobin, fluindapyr, flumorph, flumorphic, fluopicolide, fluopimomide, fluopyram, fluimide, fluoxapiprolin, fluoxapiprolin Robin (fluoxastrobin), fluquinconazole, fluquinazole, flusilazole, flusulfamide, flutianil, flutianil, flutolanil, flutriafol, fluxapiroxad fluxapyroxad), folpet, fosetyl (fosetyl), fosetyl aluminum (fosetyl-aluminium), fveridazole (fuberidazole), furaxyl (furalaxyl), furametpyr (furametpyr), guazatine, hexaconazole (hexaconazole), hymexazole hymexazole), imazalil, imibinconazole, iminoctadine, iminoctadine acetate (iminoctadine triacetate), impilfluxam (inpyrfluxam), iodocarb, iodocarb, ipconazole, ipconazole (Ipfentrifluconazole), ipflufenoquin (ipflufenoquin), iprobenfos (iprobenfos), iprodione (iprodione), iprovalicarb (iprovalicarb), isofetamide (isofetamid), isoflurcipram (isoflucypram), i Prothiolane (isoprothiolane), isopyrazam (isopyrazam), isotianil (isotianil), kasugamycin, kresoxim-methyl (kresoxim-methyl), laminarin (laminarin), mancozeb (mancozeb), mandestrobin (mandipropamide) , Maneb (maneb), mefentrifluconazole (mefentrifluconazole), mepanipyrim (mepanipyrim), mepronil (mepronil), meptyldinocap (meptyldinocap), metalaxyl (metalaxyl), metalaxyl M (metalaxyl-M), metconazole Methasulfocarb, metiram, metinominostrobin, metrafenone, methyltetraprole, metyltetraprole, mineral oils, microbutanil, myclobutanil, nafti Fin (naftifine), nuarimol (nuarimol), octillinone (octhilinone), ofurace, orysastrobin (orysastrobin), oxadixyl (oxadixyl), oxathiapiproline (oxathiapiprolin), oxine copper (oxine-copper), oxolinic acid (oxolinic acid) acid), oxpoconazole (oxpoconazole), oxpoconazole fumarate (oxpoconazole fumarate), oxycarboxin (oxycarboxin), oxytetracycline (oxytetracycline), pefurazoate (pefurazoate), penconazole (penconazole), pencicuron (pencycuron) , Penflufen, penthiopyrad, phenamacril, phosphorous acid, fusalide, phthalide, picarbutrazox, picoxystrobin, piperaline peralin), polyoxins, potassium hydrogen carbonate (potassium hydrogencarbonate), potassium dihydrogen phosphite (potassium dihydrogenphosphite), probenazole (probenazole), prochloraz (prochloraz), procymidone (procymidone), propamidine (propamidine), propamocarb (propamocarb) ), Propiconazole (propiconazole), propineb (propineb), proquinazide (proquinazid), prothiocarb (prothiocarb), prothioconazole (prothioconazole), pidiflumetofen (pydiflumetofen), pyraclostrobin (pyraclostrobin), pyrametostrobin ( pyrametostrobin), pyraoxystrobin, pyrapropoyne, pyradiflumid (pyraziflumid), pyrazophos (pyrazophos), pyribencarb (pyribencarb), pyributicarb (pyributicarb), pyridac Romethyl (pyridachlometyl), pyrifenox (pyrifenox), pyrimethanil (pyrimethanil), pyrimorph (pyrimorph), pyriophenone (pyriofenone), pyrisoxazole (pyrisoxazole), pyroquilon (pyroquilon), quinconazole (quinconazole), quinofumelin (quinofumelin), quinofumelin quinoxyfen, quintozene, quinoa saponins (Saponins of Chenopodium quinoa), sodium hydrogencarbonate (sodium hydrogencarbonate), sedaxane, silthiofam, silthiofam, simeconazole, sodium salts of phosphorous acid of phosphorous acid, spiroxamine, streptomycin, sulfur, tebuconazole, tebufloquin, tebufloquin, teclofthalam, tecnazene Terbinafine (terbinafine), tetraconazole (tetraconazole), thiabendazole (thiabendazole), thifluzamide (thifluzamide), thiophanate (thiophanate), thiophanate methyl (thiophanate-methyl), thiuram (thiram), thymol (thymol), thiazinil (tiadinil), tolclofos Methyl (tolclofos-methyl), tolfenpyrad (tolfenpyrad), tolprocarb (tolprocarb), tolylfluanid (tolylfluanid), triadimefon, triadimefon, triadimenol (triadimenol), triazoxide (triazoxide), triclopyricarb (triclopyriazole) tricyclazole), tridemorph (tridemorph), trifloxystrobin (trifloxystrobin), triflumizole (triflumizole), triforine, triticonazole (triticonazole), validamycin ( validamycin), varifenalate (valifenalate), vinclozolin (vinclozolin), mustard powder (yellow mustard powder), zineb (zineb), zinc thiazole (zinc thiazole), ziram (ziram), zoxamide (zoxamide),
At least one compound selected from the following compounds, which is an insecticide compound;
Abamectin, acephate, acequinocyl, acetamiprid, acetoprole, acetoprole, acrinathrin, acynonapyr, afidopyropene, afopyropener, afoxilaner , Aldicarb, alethrin, alpha-cypermethrin, alpha-endosulfan, aluminum phosphide, aluminum phosphide, amitraz, azadirachtin, azamethiphos , Azinphos-ethyl, azinphos-methyl, azocyclotin, bendiocarb, benfluthrin, benfuracarb , Bensultap, benzoximate, benzpyrimoxan, beta-cyfluthrin, beta-cypermethrin, beta-cypermethrin, bifenazate, bifenthrin, Bioallethrin, bioresmethrin, bistrifluron, borax, boric acid, brofuranilide, bromopropylate, buprofezin, butoxycarboxy (Butocarboxim), butoxycarboxim (butoxycarboxim), cadusafos, calcium cyanide, calcium phosphide, calcium phosphide, carbaryl, carbaryl, carbofuran, carbosulfan, Cartap Hydrochloride (cartap hydrochloride), cartap (cartap), quinomethionate (chinomethionat), chlorantraniliprole (chlorantraniliprole), chlordane (chlordane), chlorethoxyphos (chlorethoxyfos), chlorfenapyr (chlorfenapyr), chlorfenvinphos (chlorfenvinphos), chlor Fluazuron (chlorfluazuron), chlormephos (chlormephos), chlorpicrin (chloropicrin), chlorpyrifos (chlorpyrifos), chlorpyrifos-methyl (chlorpyrifos-methyl), chromafenozide (chromafenozide), clofentezine (clofentezine), conkanamycin A (concanamycin A) Coumaphos, cryolite, cyanophos, cyantraniliprole, cycloniliprole, cycloprothrin, cycloxap Lido (cycloxaprid), cyenopyrafen, cyflumetofen, cyfluthrin, cyfluthrin, cyhalodiamide, cyhalodiamide, cyhalothrin, cyhexatin, cyhexatin, cypermethrin, cyphenrin, cyothrin ), Dazomet, deltamethrin, demeton-S-methyl, diafenthiuron, diazinon, diazinon, dichlorvos, dichlororomezotiaz , Dicophor (dicofol), dicrotophos (dicrotophos), diflobidazine (diflovidazin), diflubenzuron (diflubenzuron), dimefluthrin (dimefluthrin), dimethoate (dimethoate), dimethylvinphos (dimethylvinphos), dimpropyridaz (Dimpro) pyridaz), dinotefuran, disodium octaborate, disulfoton, DNOC (2-methyl-4,6-dinitrophenol), doramectin, doramectin, emamectin-benzoate , Empentthrin, endosulfan, EPN (O-ethyl O- (4-nitrophenyl) phenylphosphonothioate), epsilon-metofluthrin, epsilon-momfluorothrin, esfenvalerate ( esfenvalerate, ethifencarb, ethifen, ethiprole, ethiprole, ethoprophos, ethoprophos, etofenprox, etoxazole, fanthur, fenamiphos, quinazaquin (aza) , Fenbuta tin oxide (fenbuta tin oxide), fenitrothion, fenobucarb, fenoxycarb, fenoxycarb, fenpropathrin, fenpyroximate, fenpyroximate, fenthion, fenvalerate, fipronil, fimetnkin flometoquin), flonicamid (flonicamid), fluacrypyrim (fluacrypyrim), fluazaindolizine (fluazaindolizine), fluazuron (fluazuron), flubendiamide (flubendiamide), flucycloxuron, flucythrinate, flucythrinate fluensulfone), flufenoxuron, flufenoxuron, flufiprole, flumethrin, flumethrin, fluopyram, flupyradifuron yradifurone), flupyrimin, fluralaner, fluvalinate, fluxametamide, formetanate, fosthiazate, furamethrin, furathiocarb, gamma cyhalothrin -cyhalothrin), GS-omega / kappa HXTX-Hv1a peptide (GS-omega / kappa HXTX-Hv1a peptide), halfenprox (halfenprox), halofenozide (halofenozide), heptafluthrin (heptafluthrin), heptenophos (heptenophos), hexa Flumuron (hexaflumuron), hexthithiazox (hexythiazox), potassium salt of hop beta acid (potassium salt), hydramethylnon (hydramethylnon), hydroprene (hydroprene), imicyafos (imicyafos), imidacloprid (imidacloprid), imidacloprid Imizclothiz, imiprothrin, indoxacarb, indoxacarb, isocycloseram, isofenphos, isoprocarb, isoprocarb, isopropyl O- (methoxyaminothiophosphoryl) salicylate (isopropyl-O- ( methoxyaminothiophosphoryl) salicylate), isoxathion, ivermectin, kadesthrin, kappa-tefluthrin, kappa-bifenthrin, kappa-bifenthrin, kinoprene, lambda bhalothin ), Lenoremycin, lepimectin, lime sulfur, lime sulfur, lotilaner, lufenuron, machine oil, malathion, mecarbam, meperfluthrin ( meperflut hrin), metaflumizone (metaflumizone), metatam (metam), methamidophos (methamidophos), methidathion (methidathion), methiocarb (methiocarb), mesomil (methomyl), methoprene (methoprene), methoxychlor (methoxychlor), methoxyphenozide (methoxyfenozide), bromide Methyl (methyl bromide), Metofluthrin (metofluthrin), Metorcarb (metolcarb), Methoxadiazone (metoxadiazone), Mevinphos (mevinphos), Milbemectin (milbemectin), Milbemycin oxime (milbemycin oxime), Monfluorothrin (monofluorosrin), Monocrotophos (monocrotophos) , Moxidectin, nared, neem oil, nicotine, nicotine-sulfate, nicotine-sulfate, nitenpyram, novaluron, noviflumuron (novi) flumuron), omethoate, oxamyl, oxazosulfyl, oxydemeton-methyl, parathion, parathion-methyl, permethrin, phenothrin phenothrin), phenthoate, phorate, phosalone, phosmet, phosmet, phosphamidon, phosphine, phoxim, phoxim, pirimicarb, pirimiphos-methyl, Potassium cyanide, praletrin (prallethrin), profenofos (profenofos), profluthrin (propfluthrin), propargite (propargite), propetamphos (propetamphos), propoxur (propoxur), propylene glycol alginate (propyl) ene glycol alginate, prothiofos, pyflubumide, pymetrozine, pyraclofos, pyrethrins, pyridaben, pyridalyl, pyridafenquinone, pyridafenquinone, pyridaphenquinone Pyrimidifen, pyriminostrobin, pyriprole, pyriproxyfen, quinalphos, quinmethos, resmethrin, rotenone, ryanodine, sarolaner, Selamectin, sigma-cypermethrin, silafluofen, sodium borate, sodium cyanide, sodium metaborate Spinetoram, spinosad, spirodiclofen, spiromesifen, spiromedifen, spiropidion, spirotetramat, sulfluramid, sulfotep, sulfoxaflor , Sulfuryl fluoride, tartar emetic, tau-fluvalinate, tebufenozide, tebufenpyrad, tebupirimfos, teflubenzuron, teflubenzuron , Temephos, terbufos, tetrachlorantraniliprole, tetrachlorvinphos, tetradifon, tetramethrin, tetramethine Lufluthrin (tetramethylfluthrin), tetraniliprole, theta-cypermethrin, thetacloprid, thiacloprid, thiamethoxam, thiocyclam, thiodicarb, thiofanox, thiofanox (Thiometon), thiosultap-disodium salt, thiosultap-monosodium salt, thiosultap-monosodium, thioxazafen, tioxazafen, tolfenpyrad, tralomethrin, transfluthrin, triazamate , Triazophos, trichlorfon, triflumezopyrim, triflumuron, trimethacarb, triclopyrazoflor (tyclopyraz) oflor), vamidothion, XMC (3,5-dimethylphenyl N-methylcarbamate), xylylcarb (xylylcarb), zeta-cypermethrin, zinc phosphide (zinc phosphide), Formula (2):

A compound Y represented by:
At least one compound selected from the following compounds, which is a plant growth regulator compound;
1-methylcyclopropene, 1,3-diphenylurea, 2,3,5-triiodobenzoic acid, IAA ((1H- indol-3-yl) acetic acid), IBA (4- (1H-indol-3-yl) butyric acid), MCPA (2- (4-chloro-2-methylphenoxy) acetic acid), MCPB (4- (4 -chloro-2-methylphenoxy) butyric acid), 4-CPA (4-chlorophenoxyacetic acid), 5-aminolevulinic acid hydrochloride, 6-benzylaminopurine (6-benzylaminopurine), abscisic acid acid), AVG (aminoethoxyvinylglycine), ancimidol (ancymidol), buturealine (butralin), calcium carbonate (calcium carbonate), calcium chloride (calcium chloride), calcium formate (calcium formate), calcium peroxide (calcium peroxide), lime Sulfur (calcium polysulfide), calcium sulfate Chlormequat-chloride, chlorpropham, chlorpropham, choline chloride, cloprop, cyanamide, cyaniamide, cyclanilide, daminozide, decan-1-ol (Decan-1-ol), dicloprop (dichlorprop), dikegulac (dikegulac), dimethipin (dimethipin), diquat (diquat), ethephon (ethephon), ethiclozate (ethychlozate), flumetralin (flumetralin), flurprimidol (flurprimidol) , Forchlorfenuron, formononetin, gibberellin A, gibberellin A3, gimexazol, inabenfide, isoprothiolane, kinetin, isoprothiolane and kinetin. (lipochitooligosaccharides such as lipochitooligosaccharide SP104), maleic hydrazide, mefluidide, mepiquat-chloride, oxidized glutathione, paclobutrazol, pendimethalin (Pendimethalin), prohexandione-calcium, prohydrojasmon, pyraflufen-ethyl, sintofen, sodium 1-naphthaleneacetate, cyanic acid Sodium (sodium cyanate), streptomycin (streptmycin), thidiazuron (thidiazuron), triapenthenol, tribufos (tribufos), trinexapac-ethyl (trinexapac-ethyl), uniconazole P (uniconazole-P), 2- (naphtha) 1-yl) acetamide (2- (naphthalene-1-yl) acetamide), [4-oxo-4- (2-phenylethyl) amino] butyric acid, 5- (trifluoromethyl) benzo [b] thiophene- Methyl 2-carboxylate, 3-[(6-chloro-4-phenylquinazolin-2-yl) amino] propan-1-ol,
And their agriculturally acceptable salts].   The weight ratio of the pesticide compound (a1) to the pesticide compound (a2) is 1/1000 to 1 / 1,000,000,000,000,000,000 for the pesticide compound (a2) / the pesticide compound (a1). 2. The pesticidal composition according to 1.   A step of applying the pesticide compound (a1) selected from the compound group A according to claim 1 and the pesticide compound (a2) selected from the compound group A according to claim 1; A pest control method wherein the weight ratio of the pesticide compound (a2) to the pesticide compound (a2) / the pesticide compound (a1) is 1/1000 or less.